product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-FoxO3a (Ser253) Antibody
catalog :
9466S
quantity :
100 ul
price :
274 USD
clonality :
polyclonal
host :
rabbit
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation
citations: 9
Published Application/Species/DilutionReference
  • western blot (knockdown validation); human; fig 3
Ahn J, Li J, Chen E, Kent D, Park H, Green A. JAK2V617F mediates resistance to DNA damage-induced apoptosis by modulating FOXO3A localization and Bcl-xL deamidation. Oncogene. 2016;35:2235-46 pubmed publisher
  • western blot; human; 1:400
Stefanetti R, Lamon S, Wallace M, Vendelbo M, Russell A, Vissing K. Regulation of ubiquitin proteasome pathway molecular markers in response to endurance and resistance exercise and training. Pflugers Arch. 2015;467:1523-37 pubmed publisher
  • western blot; human; 1:400
Stefanetti R, Zacharewicz E, Della Gatta P, Garnham A, Russell A, Lamon S. Ageing has no effect on the regulation of the ubiquitin proteasome-related genes and proteins following resistance exercise. Front Physiol. 2014;5:30 pubmed publisher
  • western blot; mouse
Ni H, Du K, You M, Ding W. Critical role of FoxO3a in alcohol-induced autophagy and hepatotoxicity. Am J Pathol. 2013;183:1815-25 pubmed publisher
  • western blot; human
Dessalle K, Euthine V, Chanon S, Delarichaudy J, Fujii I, Rome S, et al. SREBP-1 transcription factors regulate skeletal muscle cell size by controlling protein synthesis through myogenic regulatory factors. PLoS ONE. 2012;7:e50878 pubmed publisher
Ochi E, Hirose T, Hiranuma K, Min S, Ishii N, Nakazato K. Elevation of myostatin and FOXOs in prolonged muscular impairment induced by eccentric contractions in rat medial gastrocnemius muscle. J Appl Physiol (1985). 2010;108:306-13 pubmed publisher
Sykes S, Lane S, Bullinger L, Kalaitzidis D, Yusuf R, Saez B, et al. AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias. Cell. 2011;146:697-708 pubmed publisher
Chung Y, Kim H, Kim I, Yim M, Chock P. Dual function of protein kinase C (PKC) in 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced manganese superoxide dismutase (MnSOD) expression: activation of CREB and FOXO3a by PKC-alpha phosphorylation and by PKC-mediated inactivation of Akt, respective. J Biol Chem. 2011;286:29681-90 pubmed publisher
Furuya F, Lu C, Willingham M, Cheng S. Inhibition of phosphatidylinositol 3-kinase delays tumor progression and blocks metastatic spread in a mouse model of thyroid cancer. Carcinogenesis. 2007;28:2451-8 pubmed
product information
SKU :
9466S
Product-Name :
Phospho-FoxO3a (Ser253) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R, (C)
Applications :
Immunoprecipitation
Product-Category :
PI3K / Akt Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
97
Host :
Rabbit
Target :
FoxO3a (Ser253) phosphate
Primary-Protein :
FOXO3A
Alt-Names :
AF6q21,AF6q21 protein,DKFZp781A0677,FKHRL1,FKHRL1P2,FOXO2,FOXO3,FOXO3A,Forkhead box protein O3,Forkhead in rhabdomyosarcoma-like 1,MGC12739,MGC31925,forkhead box O3,forkhead box O3A,forkhead homolog (rhabdomyosarcoma) like 1,forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.