product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-FoxO3a (Ser253) Antibody
catalog :
9466
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 1e
Ali A, Kuo W, Kuo C, Lo J, Chen M, Daddam J, et al. E3 ligase activity of Carboxyl terminus of Hsc70 interacting protein (CHIP) in Wharton's jelly derived mesenchymal stem cells improves their persistence under hyperglycemic stress and promotes the prophylactic effects against diabetic cardiac damages. Bioeng Transl Med. 2021;6:e10234 pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 7b
Barbé C, Loumaye A, Lause P, Ritvos O, Thissen J. p21-Activated Kinase 1 Is Permissive for the Skeletal Muscle Hypertrophy Induced by Myostatin Inhibition. Front Physiol. 2021;12:677746 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 1a
Luo L, Zhang Z, Qiu N, Ling L, Jia X, Song Y, et al. Disruption of FOXO3a-miRNA feedback inhibition of IGF2/IGF-1R/IRS1 signaling confers Herceptin resistance in HER2-positive breast cancer. Nat Commun. 2021;12:2699 pubmed publisher
  • western blot; human; loading ...; fig 9b
Zhao W, Zhang W, Ma H, Yang M. NIPA2 regulates osteoblast function by modulating mitophagy in type 2 diabetes osteoporosis. Sci Rep. 2020;10:3078 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3d
Yue D, Sun X. Idelalisib promotes Bim-dependent apoptosis through AKT/FoxO3a in hepatocellular carcinoma. Cell Death Dis. 2018;9:935 pubmed publisher
  • western blot; human; fig 2b
Barrow A, Edeling M, Trifonov V, Luo J, Goyal P, Bohl B, et al. Natural Killer Cells Control Tumor Growth by Sensing a Growth Factor. Cell. 2018;172:534-548.e19 pubmed publisher
  • western blot; human; loading ...; fig s3a
Gupta A, Anjomani Virmouni S, Koundouros N, Dimitriadi M, Choo Wing R, Valle A, et al. PARK2 Depletion Connects Energy and Oxidative Stress to PI3K/Akt Activation via PTEN S-Nitrosylation. Mol Cell. 2017;65:999-1013.e7 pubmed publisher
  • western blot; human; fig 3
Kline C, van den Heuvel A, Allen J, Prabhu V, Dicker D, El Deiry W. ONC201 kills solid tumor cells by triggering an integrated stress response dependent on ATF4 activation by specific eIF2α kinases. Sci Signal. 2016;9:ra18 pubmed publisher
  • western blot; human; fig 3
Ahn J, Li J, Chen E, Kent D, Park H, Green A. JAK2V617F mediates resistance to DNA damage-induced apoptosis by modulating FOXO3A localization and Bcl-xL deamidation. Oncogene. 2016;35:2235-46 pubmed publisher
Chen Y, Lv L, Pi H, Qin W, Chen J, Guo D, et al. Dihydromyricetin protects against liver ischemia/reperfusion induced apoptosis via activation of FOXO3a-mediated autophagy. Oncotarget. 2016;7:76508-76522 pubmed publisher
product information
SKU :
9466S
Product-Name :
Phospho-FoxO3a (Ser253) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R, (C)
Applications :
Immunoprecipitation
Product-Category :
PI3K / Akt Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
97
Host :
Rabbit
Target :
FoxO3a (Ser253) phosphate
Primary-Protein :
FOXO3A
Alt-Names :
AF6q21,AF6q21 protein,DKFZp781A0677,FKHRL1,FKHRL1P2,FOXO2,FOXO3,FOXO3A,Forkhead box protein O3,Forkhead in rhabdomyosarcoma-like 1,MGC12739,MGC31925,forkhead box O3,forkhead box O3A,forkhead homolog (rhabdomyosarcoma) like 1,forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.