Phospho-4E-BP1 (Thr37/46) Antibody | Cell Signaling Technology 9459L product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Phospho-4E-BP1 (Thr37/46) Antibody

catalog :

9459L

quantity :

300 ul

price :

658 USD

clonality :

polyclonal

host :

rabbit

antigen modification :

phosphorylated

reactivity :

human, mouse, rat, cat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

Cell Signaling Technology product webpage

citations: 17

Published Application/Species/Dilution	Reference
western blot; mouse; fig s4	Ruegsegger C, Stucki D, Steiner S, Angliker N, Radecke J, Keller E, et al. Impaired mTORC1-Dependent Expression of Homer-3 Influences SCA1 Pathophysiology. Neuron. 2016;89:129-46 pubmed publisher
western blot; mouse; fig s5	Gong Q, Hu Z, Zhang F, Cui A, Chen X, Jiang H, et al. Fibroblast growth factor 21 improves hepatic insulin sensitivity by inhibiting mammalian target of rapamycin complex 1 in mice. Hepatology. 2016;: pubmed publisher
western blot; cat; fig 4	Humoud M, Doyle N, Royall E, Willcocks M, Sorgeloos F, van Kuppeveld F, et al. Feline Calicivirus Infection Disrupts Assembly of Cytoplasmic Stress Granules and Induces G3BP1 Cleavage. J Virol. 2016;90:6489-501 pubmed publisher
western blot; human; 1:1000; fig 2c	Deblois G, Smith H, Tam I, Gravel S, Caron M, Savage P, et al. ERRα mediates metabolic adaptations driving lapatinib resistance in breast cancer. Nat Commun. 2016;7:12156 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:200; fig s5	Yamano S, Gi M, Tago Y, Doi K, Okada S, Hirayama Y, et al. Role of deltaNp63(pos) CD44v(pos) cells in the development of N-nitroso-tris-chloroethylurea-induced peripheral-type mouse lung squamous cell carcinomas. Cancer Sci. 2016;107:123-32 pubmed publisher
western blot; human	Roffe M, Lupinacci F, Soares L, Hajj G, Martins V. Two widely used RSK inhibitors, BI-D1870 and SL0101, alter mTORC1 signaling in a RSK-independent manner. Cell Signal. 2015;27:1630-42 pubmed publisher
western blot; mouse; 1:1000; fig 2	Milan G, Romanello V, Pescatore F, Armani A, Paik J, Frasson L, et al. Regulation of autophagy and the ubiquitin-proteasome system by the FoxO transcriptional network during muscle atrophy. Nat Commun. 2015;6:6670 pubmed publisher
western blot; mouse; fig 5 immunohistochemistry; mouse; fig 5	Hu X, Garcia C, Fazli L, Gleave M, Vitek M, Jansen M, et al. Inhibition of Pten deficient Castration Resistant Prostate Cancer by Targeting of the SET - PP2A Signaling axis. Sci Rep. 2015;5:15182 pubmed publisher
western blot; human	Maliqueo M, Sundstrom Poromaa I, Vanky E, Fornes R, Benrick A, Akerud H, et al. Placental STAT3 signaling is activated in women with polycystic ovary syndrome. Hum Reprod. 2015;30:692-700 pubmed publisher
western blot; human; 1:1000	Webber P, Park C, Qui M, Ramalingam S, Khuri F, Fu H, et al. Combination of heat shock protein 90 and focal adhesion kinase inhibitors synergistically inhibits the growth of non-small cell lung cancer cells. Oncoscience. 2015;2:765-76 pubmed
western blot; human; fig 4a	Li X, Cui P, Jiang H, Guo Y, Pishdari B, Hu M, et al. Reversing the reduced level of endometrial GLUT4 expression in polycystic ovary syndrome: a mechanistic study of metformin action. Am J Transl Res. 2015;7:574-86 pubmed
western blot; human	Perera Y, Pedroso S, Borras-Hidalgo O, Vázquez D, Miranda J, Villareal A, et al. Pharmacologic inhibition of the CK2-mediated phosphorylation of B23/NPM in cancer cells selectively modulates genes related to protein synthesis, energetic metabolism, and ribosomal biogenesis. Mol Cell Biochem. 2015;404:103-12 pubmed publisher
western blot; rat; fig 5	Asano S, Arvapalli R, Manne N, Maheshwari M, Ma B, Rice K, et al. Cerium oxide nanoparticle treatment ameliorates peritonitis-induced diaphragm dysfunction. Int J Nanomedicine. 2015;10:6215-25 pubmed publisher
western blot; human; 1:1000; fig 1	Yu P, Laird A, Du X, Wu J, Won K, Yamaguchi K, et al. Characterization of the activity of the PI3K/mTOR inhibitor XL765 (SAR245409) in tumor models with diverse genetic alterations affecting the PI3K pathway. Mol Cancer Ther. 2014;13:1078-91 pubmed publisher
western blot; human; fig 4	Su W, Chao T, Huang Y, Weng S, Jeng K, Lai M. Rab5 and class III phosphoinositide 3-kinase Vps34 are involved in hepatitis C virus NS4B-induced autophagy. J Virol. 2011;85:10561-71 pubmed publisher
	Ma D, Yu H, Lin D, Sun Y, Liu L, Liu Y, et al. S6K1 is involved in polyploidization through its phosphorylation at Thr421/Ser424. J Cell Physiol. 2009;219:31-44 pubmed publisher
	Ohne Y, Takahara T, Hatakeyama R, Matsuzaki T, Noda M, Mizushima N, et al. Isolation of hyperactive mutants of mammalian target of rapamycin. J Biol Chem. 2008;283:31861-70 pubmed publisher

product information

SKU :

9459L

Product-Name :

Phospho-4E-BP1 (Thr37/46) Antibody

Size :

300 ul

Price-(USD) :

658 USD

Species-x-Reactivity :

H, M, R, Mk

Applications :

Western blot

Product-Category :

Translational Control

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Polyclonal Antibody

MW :

15 to 20

Host :

Rabbit

Target :

4E-BP1 (Thr37/Thr46) phosphate

Primary-Protein :

4E-BP1

Alt-Names :

4E-BP1,4EBP1,BP-1,EIF4EBP1,Eukaryotic translation initiation factor 4E-binding protein 1,MGC4316,PHAS-I,Phosphorylated heat- and acid-stable protein regulated by insulin 1,eIF4E-binding protein 1,eukaryotic translation initiation factor 4E binding protein 1

more info or order :

Cell Signaling Technology product webpage