product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-4E-BP1 (Ser65) (174A9) Rabbit mAb
catalog :
9456S
quantity :
100 ul
price :
274 USD
clonality :
monoclonal
host :
rabbit
antigen modification :
phosphorylated
reactivity :
human, mouse
application :
western blot, immunoprecipitation
citations: 8
Published Application/Species/DilutionReference
  • western blot; human; 1:1000; fig 1
Gandin V, Masvidal L, Cargnello M, Gyenis L, McLaughlan S, Cai Y, et al. mTORC1 and CK2 coordinate ternary and eIF4F complex assembly. Nat Commun. 2016;7:11127 pubmed publisher
  • western blot; human; fig 5
Rasmussen M, Lyskjær I, Jersie-Christensen R, Tarpgaard L, Primdal-Bengtson B, Nielsen M, et al. miR-625-3p regulates oxaliplatin resistance by targeting MAP2K6-p38 signalling in human colorectal adenocarcinoma cells. Nat Commun. 2016;7:12436 pubmed publisher
  • western blot; human
Zhang L, Dai F, Cui L, Jing H, Fan P, Tan X, et al. Novel role for TRPC4 in regulation of macroautophagy by a small molecule in vascular endothelial cells. Biochim Biophys Acta. 2015;1853:377-87 pubmed publisher
  • western blot; mouse; 1:5000; fig 3
Li S, TANG J, Chen J, Zhang P, Wang T, Chen T, et al. Regulation of bone formation by baicalein via the mTORC1 pathway. Drug Des Devel Ther. 2015;9:5169-83 pubmed publisher
  • western blot; human
Wang S, Chen X, Hu J, Jiang J, Li Y, Chan-Salis K, et al. ATF4 Gene Network Mediates Cellular Response to the Anticancer PAD Inhibitor YW3-56 in Triple-Negative Breast Cancer Cells. Mol Cancer Ther. 2015;14:877-88 pubmed publisher
Groenendijk F, Mellema W, van der Burg E, Schut E, Hauptmann M, Horlings H, et al. Sorafenib synergizes with metformin in NSCLC through AMPK pathway activation. Int J Cancer. 2015;136:1434-44 pubmed publisher
Gomez-Abad C, Pisonero H, Blanco-Aparicio C, Roncador G, Gonzalez-Menchen A, Martinez-Climent J, et al. PIM2 inhibition as a rational therapeutic approach in B-cell lymphoma. Blood. 2011;118:5517-27 pubmed publisher
Matsuo J, Tsukumo Y, Saito S, Tsukahara S, Sakurai J, Sato S, et al. Hyperactivation of 4E-binding protein 1 as a mediator of biguanide-induced cytotoxicity during glucose deprivation. Mol Cancer Ther. 2012;11:1082-91 pubmed publisher
product information
SKU :
9456S
Product-Name :
Phospho-4E-BP1 (Ser65) (174A9) Rabbit mAb
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, Mk, (C)
Applications :
Immunoprecipitation
Product-Category :
Translational Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
15-20
Host :
Rabbit
Target :
4E-BP1 (Ser65) phosphate
Primary-Protein :
4E-BP1
Alt-Names :
4E-BP1,4EBP1,BP-1,EIF4EBP1,Eukaryotic translation initiation factor 4E-binding protein 1,MGC4316,PHAS-I,Phosphorylated heat- and acid-stable protein regulated by insulin 1,eIF4E-binding protein 1,eukaryotic translation initiation factor 4E binding protein 1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.