Published Application/Species/Sample/Dilution | Reference |
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- western blot; human; loading ...; fig 3f
| Hu F, Song D, Yan Y, Huang C, Shen C, Lan J, et al. IL-6 regulates autophagy and chemotherapy resistance by promoting BECN1 phosphorylation. Nat Commun. 2021;12:3651 pubmed publisher
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- western blot; human; loading ...; fig s5c
| Zhou J, Cui S, He Q, Guo Y, Pan X, Zhang P, et al. SUMOylation inhibitors synergize with FXR agonists in combating liver fibrosis. Nat Commun. 2020;11:240 pubmed publisher
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- western blot; human; loading ...; fig 6e
| Gao X, Zhao L, Liu S, Li Y, Xia S, Chen D, et al. γ-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A. Mol Cell. 2019;76:857-871.e9 pubmed publisher
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- western blot; mouse; 1:1000; loading ...; fig 6e
| Zhang H, Sathyamurthy A, Liu F, Li L, Zhang L, Dong Z, et al. Agrin-Lrp4-Ror2 signaling regulates adult hippocampal neurogenesis in mice. elife. 2019;8: pubmed publisher
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- western blot; human; loading ...; fig s3a
| Kennedy S, Han J, Portman N, Nobis M, Hastings J, Murphy K, et al. Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer. Breast Cancer Res. 2019;21:43 pubmed publisher
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- western blot; human; loading ...; fig 5b
| Hou L, Zhao J, Gao S, Ji T, Song T, Li Y, et al. Restriction of hepatitis B virus replication by c-Abl-induced proteasomal degradation of the viral polymerase. Sci Adv. 2019;5:eaau7130 pubmed publisher
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- immunohistochemistry - paraffin section; human
- immunohistochemistry; human
| Lin J, Izar B, Wang S, Yapp C, Mei S, Shah P, et al. Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes. elife. 2018;7: pubmed publisher
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- immunocytochemistry; human; 1:100; loading ...; fig 2e
- western blot; human; loading ...; fig 1c
- immunocytochemistry; mouse; 1:100; loading ...; fig 3c
| Carpenter V, Chen Y, Dolat L, Valdivia R. The Effector TepP Mediates Recruitment and Activation of Phosphoinositide 3-Kinase on Early Chlamydia trachomatis Vacuoles. mSphere. 2017;2: pubmed publisher
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- immunoprecipitation; mouse; fig 2a
| Matsumoto Y, La Rose J, Kent O, Wagner M, Narimatsu M, Levy A, et al. Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2. J Clin Invest. 2016;126:4482-4496 pubmed publisher
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- western blot; mouse; 1:2000; fig 6
| Sun X, Li L, Liu F, Huang Z, Bean J, Jiao H, et al. Lrp4 in astrocytes modulates glutamatergic transmission. Nat Neurosci. 2016;19:1010-8 pubmed publisher
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- western blot; human; loading ...; fig s7a
| Francavilla C, Papetti M, Rigbolt K, Pedersen A, Sigurdsson J, Cazzamali G, et al. Multilayered proteomics reveals molecular switches dictating ligand-dependent EGFR trafficking. Nat Struct Mol Biol. 2016;23:608-18 pubmed publisher
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- immunocytochemistry; human; 1:400; fig 6
| Horton E, Humphries J, Stutchbury B, Jacquemet G, Ballestrem C, Barry S, et al. Modulation of FAK and Src adhesion signaling occurs independently of adhesion complex composition. J Cell Biol. 2016;212:349-64 pubmed publisher
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- western blot; human; fig 6
| DÃaz Barreiro A, Bernal Quirós M, Georg I, Marañón C, Alarcón Riquelme M, Castillejo López C. The SLE variant Ala71Thr of BLK severely decreases protein abundance and binding to BANK1 through impairment of the SH3 domain function. Genes Immun. 2016;17:128-38 pubmed publisher
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- western blot; human; 1:1000
| Lee S, Frattini V, Bansal M, Castano A, Sherman D, Hutchinson K, et al. An ID2-dependent mechanism for VHL inactivation in cancer. Nature. 2016;529:172-7 pubmed publisher
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- immunoprecipitation; human; fig 1c
| Wu X, Zahari M, Renuse S, Nirujogi R, Kim M, Manda S, et al. Phosphoproteomic Analysis Identifies Focal Adhesion Kinase 2 (FAK2) as a Potential Therapeutic Target for Tamoxifen Resistance in Breast Cancer. Mol Cell Proteomics. 2015;14:2887-900 pubmed publisher
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- other; mouse; 1:2000; fig s1
| Chiang C, Uzoma I, Lane D, Memišević V, Alem F, Yao K, et al. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Front Microbiol. 2015;6:683 pubmed publisher
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- western blot; human; 1:2000; fig 3
| Bugaj L, Spelke D, Mesuda C, Varedi M, Kane R, Schaffer D. Regulation of endogenous transmembrane receptors through optogenetic Cry2 clustering. Nat Commun. 2015;6:6898 pubmed publisher
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- western blot; mouse; fig 2
| Naik E, Webster J, DeVoss J, Liu J, Suriben R, Dixit V. Regulation of proximal T cell receptor signaling and tolerance induction by deubiquitinase Usp9X. J Exp Med. 2014;211:1947-55 pubmed publisher
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- immunoprecipitation; mouse; 1:100; fig 4
| Moorwood C, Philippou A, Spinazzola J, Keyser B, Macarak E, Barton E. Absence of ?-sarcoglycan alters the response of p70S6 kinase to mechanical perturbation in murine skeletal muscle. Skelet Muscle. 2014;4:13 pubmed publisher
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| Orfi Z, Wáczek F, Baska F, Szabadkai I, Torka R, Hartmann J, et al. Novel members of quinoline compound family enhance insulin secretion in RIN-5AH beta cells and in rat pancreatic islet microtissue. Sci Rep. 2017;7:44073 pubmed publisher
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| Gao S, Geng C, Song T, Lin X, Liu J, Cai Z, et al. Activation of c-Abl Kinase Potentiates the Anti-myeloma Drug Lenalidomide by Promoting DDA1 Protein Recruitment to the CRL4 Ubiquitin Ligase. J Biol Chem. 2017;292:3683-3691 pubmed publisher
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| Zhang J, Wang S, Jiang B, Huang L, Ji Z, Li X, et al. c-Src phosphorylation and activation of hexokinase promotes tumorigenesis and metastasis. Nat Commun. 2017;8:13732 pubmed publisher
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| Lin C, Lin W, Cho R, Wang C, Hsiao L, Yang C. TNF-?-Induced cPLA2 Expression via NADPH Oxidase/Reactive Oxygen Species-Dependent NF-?B Cascade on Human Pulmonary Alveolar Epithelial Cells. Front Pharmacol. 2016;7:447 pubmed
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| Cheng H, Burroughs Garcia J, Birkness J, Trinidad J, Deans M. Disparate Regulatory Mechanisms Control Fat3 and P75NTR Protein Transport through a Conserved Kif5-Interaction Domain. PLoS ONE. 2016;11:e0165519 pubmed publisher
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| Theriault P, ElAli A, Rivest S. High fat diet exacerbates Alzheimer's disease-related pathology in APPswe/PS1 mice. Oncotarget. 2016;7:67808-67827 pubmed publisher
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| Justa Schuch D, Silva Garcia M, Pilla E, Engelke M, Kilisch M, Lenz C, et al. DPP9 is a novel component of the N-end rule pathway targeting the tyrosine kinase Syk. elife. 2016;5: pubmed publisher
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| Jadwin J, Oh D, Curran T, Ogiue Ikeda M, Jia L, White F, et al. Time-resolved multimodal analysis of Src Homology 2 (SH2) domain binding in signaling by receptor tyrosine kinases. elife. 2016;5:e11835 pubmed publisher
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| Altuntas S, Rossin F, Marsella C, D Eletto M, Diaz Hidalgo L, Farrace M, et al. The transglutaminase type 2 and pyruvate kinase isoenzyme M2 interplay in autophagy regulation. Oncotarget. 2015;6:44941-54 pubmed publisher
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| Friedman A, Amzallag A, Pruteanu Malinici I, Baniya S, Cooper Z, Piris A, et al. Landscape of Targeted Anti-Cancer Drug Synergies in Melanoma Identifies a Novel BRAF-VEGFR/PDGFR Combination Treatment. PLoS ONE. 2015;10:e0140310 pubmed publisher
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| Cao X, Kaneko T, Li J, Liu A, Voss C, Li S. A phosphorylation switch controls the spatiotemporal activation of Rho GTPases in directional cell migration. Nat Commun. 2015;6:7721 pubmed publisher
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| Koos B, Cane G, Grannas K, Löf L, Arngården L, Heldin J, et al. Proximity-dependent initiation of hybridization chain reaction. Nat Commun. 2015;6:7294 pubmed publisher
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| Tampella G, Kerns H, Niu D, Singh S, Khim S, Bosch K, et al. The Tec Kinase-Regulated Phosphoproteome Reveals a Mechanism for the Regulation of Inhibitory Signals in Murine Macrophages. J Immunol. 2015;195:246-56 pubmed publisher
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| Lou S, Diz Muñoz A, Weiner O, Fletcher D, Theriot J. Myosin light chain kinase regulates cell polarization independently of membrane tension or Rho kinase. J Cell Biol. 2015;209:275-88 pubmed publisher
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| Iorio V, Festa M, Rosati A, Hahne M, Tiberti C, Capunzo M, et al. BAG3 regulates formation of the SNARE complex and insulin secretion. Cell Death Dis. 2015;6:e1684 pubmed publisher
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| Mills R, Mita M, Nakagawa J, Shoji M, Sutherland C, Walsh M. A role for the tyrosine kinase Pyk2 in depolarization-induced contraction of vascular smooth muscle. J Biol Chem. 2015;290:8677-92 pubmed publisher
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| Tulake K, Wang X, Chen Y, Yu C, Jing B, Li H. Protein tyrosine phosphorylation during capacitation in sperm of a rare red deer, Tarim wapiti (Cervus elaphus yarkandensis). Anim Reprod Sci. 2015;154:68-78 pubmed publisher
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| Suraneni P, Fogelson B, Rubinstein B, Noguera P, Volkmann N, Hanein D, et al. A mechanism of leading-edge protrusion in the absence of Arp2/3 complex. Mol Biol Cell. 2015;26:901-12 pubmed publisher
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| Wiens O, Xia D, von Schubert C, Wastling J, Dobbelaere D, Heussler V, et al. Cell cycle-dependent phosphorylation of Theileria annulata schizont surface proteins. PLoS ONE. 2014;9:e103821 pubmed publisher
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| Lind J, Backert S, Pfleiderer K, Berg D, Yamaoka Y, Sticht H, et al. Systematic analysis of phosphotyrosine antibodies recognizing single phosphorylated EPIYA-motifs in CagA of Western-type Helicobacter pylori strains. PLoS ONE. 2014;9:e96488 pubmed publisher
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| Guilgur L, Prudêncio P, Sobral D, Liszeková D, Rosa A, Martinho R. Requirement for highly efficient pre-mRNA splicing during Drosophila early embryonic development. elife. 2014;3:e02181 pubmed publisher
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| Tobin G, Zhang J, Goodwin D, Stewart S, Xu L, Knapton A, et al. The role of eNOS phosphorylation in causing drug-induced vascular injury. Toxicol Pathol. 2014;42:709-24 pubmed publisher
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| Chesarino N, McMichael T, Hach J, Yount J. Phosphorylation of the antiviral protein interferon-inducible transmembrane protein 3 (IFITM3) dually regulates its endocytosis and ubiquitination. J Biol Chem. 2014;289:11986-92 pubmed publisher
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| Chen Y, Bastidas R, Saka H, Carpenter V, Richards K, Plano G, et al. The Chlamydia trachomatis type III secretion chaperone Slc1 engages multiple early effectors, including TepP, a tyrosine-phosphorylated protein required for the recruitment of CrkI-II to nascent inclusions and innate immune signaling. PLoS Pathog. 2014;10:e1003954 pubmed publisher
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| Ma M, Baumgartner M. Filopodia and membrane blebs drive efficient matrix invasion of macrophages transformed by the intracellular parasite Theileria annulata. PLoS ONE. 2013;8:e75577 pubmed publisher
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| Sima N, Cheng X, Ye F, Ma D, Xie X, Lu W. The overexpression of scaffolding protein NEDD9 promotes migration and invasion in cervical cancer via tyrosine phosphorylated FAK and SRC. PLoS ONE. 2013;8:e74594 pubmed publisher
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| Wiradjaja F, Cottle D, Jones L, Smyth I. Regulation of PDGFC signalling and extracellular matrix composition by FREM1 in mice. Dis Model Mech. 2013;6:1426-33 pubmed publisher
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| Saldana S, Lee H, Lowery F, Khotskaya Y, Xia W, Zhang C, et al. Inhibition of type I insulin-like growth factor receptor signaling attenuates the development of breast cancer brain metastasis. PLoS ONE. 2013;8:e73406 pubmed publisher
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| Pease B, Huttlin E, Jedrychowski M, Talevich E, Harmon J, Dillman T, et al. Global analysis of protein expression and phosphorylation of three stages of Plasmodium falciparum intraerythrocytic development. J Proteome Res. 2013;12:4028-45 pubmed publisher
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| Taipale M, Krykbaeva I, Whitesell L, Santagata S, Zhang J, Liu Q, et al. Chaperones as thermodynamic sensors of drug-target interactions reveal kinase inhibitor specificities in living cells. Nat Biotechnol. 2013;31:630-7 pubmed publisher
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| Sigurdsson V, Ingthorsson S, Hilmarsdottir B, Gustafsdottir S, Franzdóttir S, Arason A, et al. Expression and functional role of sprouty-2 in breast morphogenesis. PLoS ONE. 2013;8:e60798 pubmed publisher
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| Bernal Quirós M, Wu Y, Alarcon Riquelme M, Castillejo Lopez C. BANK1 and BLK act through phospholipase C gamma 2 in B-cell signaling. PLoS ONE. 2013;8:e59842 pubmed publisher
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| Slanina H, Hebling S, Hauck C, Schubert Unkmeir A. Cell invasion by Neisseria meningitidis requires a functional interplay between the focal adhesion kinase, Src and cortactin. PLoS ONE. 2012;7:e39613 pubmed publisher
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| Ji L, Jayachandran G, Roth J. High throughput profiling of serum phosphoproteins/peptides using the SELDI-TOF-MS platform. Methods Mol Biol. 2012;818:199-216 pubmed publisher
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| Chong T, Stary J, Wang Y, Newmark P. Molecular markers to characterize the hermaphroditic reproductive system of the planarian Schmidtea mediterranea. BMC Dev Biol. 2011;11:69 pubmed publisher
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| Hereng T, Elgstøen K, Cederkvist F, Eide L, Jahnsen T, Skalhegg B, et al. Exogenous pyruvate accelerates glycolysis and promotes capacitation in human spermatozoa. Hum Reprod. 2011;26:3249-63 pubmed publisher
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| Weibrecht I, Grundberg I, Nilsson M, Söderberg O. Simultaneous visualization of both signaling cascade activity and end-point gene expression in single cells. PLoS ONE. 2011;6:e20148 pubmed publisher
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| Khusial P, Vadla B, Krishnan H, Ramlall T, Shen Y, Ichikawa H, et al. Src activates Abl to augment Robo1 expression in order to promote tumor cell migration. Oncotarget. 2010;1:198-209 pubmed
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| Rubert J, Qian Z, Andraos R, Guthy D, Radimerski T. Bim and Mcl-1 exert key roles in regulating JAK2V617F cell survival. BMC Cancer. 2011;11:24 pubmed publisher
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| Jackman J, Chen Y, Huang A, Moffat B, Scheer J, Leong S, et al. Development of a two-part strategy to identify a therapeutic human bispecific antibody that inhibits IgE receptor signaling. J Biol Chem. 2010;285:20850-9 pubmed publisher
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| Ye Z, Kluger Y, Lian Z, Weissman S. Two types of precursor cells in a multipotential hematopoietic cell line. Proc Natl Acad Sci U S A. 2005;102:18461-6 pubmed
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| Smith J, Poteet Smith C, Xu Y, Errington T, Hecht S, Lannigan D. Identification of the first specific inhibitor of p90 ribosomal S6 kinase (RSK) reveals an unexpected role for RSK in cancer cell proliferation. Cancer Res. 2005;65:1027-34 pubmed
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