product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
c-Myc Antibody
catalog :
9402
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section, ChIP-Seq, reverse phase protein lysate microarray
citations: 33
Published Application/Species/Sample/DilutionReference
  • chromatin immunoprecipitation; human; 1:50; loading ...; fig 5a
Wu S, Xiao Y, Wei J, Xu X, Jin X, Hu X, et al. MYC suppresses STING-dependent innate immunity by transcriptionally upregulating DNMT1 in triple-negative breast cancer. J Immunother Cancer. 2021;9: pubmed publisher
  • chromatin immunoprecipitation; human; loading ...; fig 7b
Chen D, Zhao Z, Chen L, Li Q, Zou J, Liu S. PPM1G promotes the progression of hepatocellular carcinoma via phosphorylation regulation of alternative splicing protein SRSF3. Cell Death Dis. 2021;12:722 pubmed publisher
  • western blot; human; loading ...; fig s3e
Luo C, Xu X, Liu C, He S, Chen J, Feng Y, et al. RBFOX2/GOLIM4 Splicing Axis Activates Vesicular Transport Pathway to Promote Nasopharyngeal Carcinogenesis. Adv Sci (Weinh). 2021;8:e2004852 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5j
Laine A, Nagelli S, Farrington C, Butt U, Cvrljevic A, Vainonen J, et al. CIP2A Interacts with TopBP1 and Drives Basal-Like Breast Cancer Tumorigenesis. Cancer Res. 2021;81:4319-4331 pubmed publisher
  • western blot; human; loading ...; fig 4e
Daks A, Petukhov A, Fedorova O, Shuvalov O, Kizenko A, Tananykina E, et al. The RNA-binding protein HuR is a novel target of Pirh2 E3 ubiquitin ligase. Cell Death Dis. 2021;12:581 pubmed publisher
  • chromatin immunoprecipitation; human; loading ...; fig 5g
Zhang J, Yang P, Liu D, Gao M, Wang J, Wang X, et al. c-Myc Upregulated by High Glucose Inhibits HaCaT Differentiation by S100A6 Transcriptional Activation. Front Endocrinol (Lausanne). 2021;12:676403 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5a
Lu M, Qin X, Zhou Y, Li G, Liu Z, Geng X, et al. Long non-coding RNA LINC00665 promotes gemcitabine resistance of Cholangiocarcinoma cells via regulating EMT and stemness properties through miR-424-5p/BCL9L axis. Cell Death Dis. 2021;12:72 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3s2b
Zhang H, Zhang Y, Zhou X, Wright S, Hyle J, Zhao L, et al. Functional interrogation of HOXA9 regulome in MLLr leukemia via reporter-based CRISPR/Cas9 screen. elife. 2020;9: pubmed publisher
  • western blot; mouse; loading ...; fig 6i
Cui J, Duan J, Chu J, Guo C, Xi M, Li Y, et al. Chikusetsu saponin IVa protects pancreatic β cell against intermittent high glucose-induced injury by activating Wnt/β-catenin/TCF7L2 pathway. Aging (Albany NY). 2020;12:1591-1609 pubmed publisher
  • ChIP-Seq; human; loading ...; fig 2b
  • chromatin immunoprecipitation; human; loading ...; fig 1d
Weissmiller A, Wang J, Lorey S, Howard G, Martinez E, Liu Q, et al. Inhibition of MYC by the SMARCB1 tumor suppressor. Nat Commun. 2019;10:2014 pubmed publisher
  • western blot; human; loading ...; fig 4b
Dufour F, Silina L, Neyret Kahn H, Moreno Vega A, Krucker C, Karboul N, et al. TYRO3 as a molecular target for growth inhibition and apoptosis induction in bladder cancer. Br J Cancer. 2019;120:555-564 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig s8a
  • western blot; mouse; loading ...; fig s8b
  • western blot; human; fig s8c, s8d
Wang Y, Du L, Liang X, Meng P, Bi L, Wang Y, et al. Sirtuin 4 Depletion Promotes Hepatocellular Carcinoma Tumorigenesis Through Regulating Adenosine-Monophosphate-Activated Protein Kinase Alpha/Mammalian Target of Rapamycin Axis in Mice. Hepatology. 2018;: pubmed publisher
  • western blot; human; fig 5g
  • western blot; mouse; loading ...; fig 5h
Kim S, Knight D, Jones L, Vervoort S, Ng A, Seymour J, et al. JAK2 is dispensable for maintenance of JAK2 mutant B-cell acute lymphoblastic leukemias. Genes Dev. 2018;32:849-864 pubmed publisher
  • western blot; mouse; loading ...; fig e8j
Du X, Wen J, Wang Y, Karmaus P, Khatamian A, Tan H, et al. Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells. Nature. 2018;558:141-145 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3b
Sevin M, Kubovcakova L, Pernet N, Causse S, Vitte F, Villeval J, et al. HSP27 is a partner of JAK2-STAT5 and a potential therapeutic target in myelofibrosis. Nat Commun. 2018;9:1431 pubmed publisher
  • western blot; rat; loading ...; fig 5b
Ogasawara R, Fujita S, Hornberger T, Kitaoka Y, Makanae Y, Nakazato K, et al. The role of mTOR signalling in the regulation of skeletal muscle mass in a rodent model of resistance exercise. Sci Rep. 2016;6:31142 pubmed publisher
Yu P, Wilhelm K, Dubrac A, Tung J, Alves T, Fang J, et al. FGF-dependent metabolic control of vascular development. Nature. 2017;545:224-228 pubmed publisher
Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
Dey K, Bharti R, Dey G, Pal I, Rajesh Y, Chavan S, et al. S100A7 has an oncogenic role in oral squamous cell carcinoma by activating p38/MAPK and RAB2A signaling pathway. Cancer Gene Ther. 2016;23:382-391 pubmed publisher
Lombardi O, Varshney D, Phillips N, Cowling V. c-Myc deregulation induces mRNA capping enzyme dependency. Oncotarget. 2016;7:82273-82288 pubmed publisher
King B, Boccalatte F, Moran Crusio K, Wolf E, Wang J, Kayembe C, et al. The ubiquitin ligase Huwe1 regulates the maintenance and lymphoid commitment of hematopoietic stem cells. Nat Immunol. 2016;17:1312-1321 pubmed publisher
Myasnikov A, Kundhavai Natchiar S, Nebout M, Hazemann I, Imbert V, Khatter H, et al. Structure-function insights reveal the human ribosome as a cancer target for antibiotics. Nat Commun. 2016;7:12856 pubmed publisher
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
Haider S, McIntyre A, van Stiphout R, Winchester L, Wigfield S, Harris A, et al. Genomic alterations underlie a pan-cancer metabolic shift associated with tumour hypoxia. Genome Biol. 2016;17:140 pubmed publisher
Li H, Mai R, Huang H, Chou C, Chang Y, Chang Y, et al. DDX3 Represses Stemness by Epigenetically Modulating Tumor-suppressive miRNAs in Hepatocellular Carcinoma. Sci Rep. 2016;6:28637 pubmed publisher
Verbist K, Guy C, Milasta S, Liedmann S, Kaminski M, Wang R, et al. Metabolic maintenance of cell asymmetry following division in activated T lymphocytes. Nature. 2016;532:389-93 pubmed publisher
Palanichamy J, Tran T, Howard J, Contreras J, Fernando T, Sterne Weiler T, et al. RNA-binding protein IGF2BP3 targeting of oncogenic transcripts promotes hematopoietic progenitor proliferation. J Clin Invest. 2016;126:1495-511 pubmed publisher
Perumal D, Kuo P, Leshchenko V, Jiang Z, Divakar S, Cho H, et al. Dual Targeting of CDK4 and ARK5 Using a Novel Kinase Inhibitor ON123300 Exerts Potent Anticancer Activity against Multiple Myeloma. Cancer Res. 2016;76:1225-36 pubmed publisher
Haque M, Song J, Fino K, Wang Y, Sandhu P, Song X, et al. C-Myc regulation by costimulatory signals modulates the generation of CD8+ memory T cells during viral infection. Open Biol. 2016;6:150208 pubmed publisher
Wilhelm K, Happel K, Eelen G, Schoors S, Oellerich M, Lim R, et al. FOXO1 couples metabolic activity and growth state in the vascular endothelium. Nature. 2016;529:216-20 pubmed publisher
Diersch S, Wirth M, Schneeweis C, Jörs S, Geisler F, Siveke J, et al. Kras(G12D) induces EGFR-MYC cross signaling in murine primary pancreatic ductal epithelial cells. Oncogene. 2016;35:3880-6 pubmed publisher
Fan L, Peng G, Sahgal N, Fazli L, Gleave M, Zhang Y, et al. Regulation of c-Myc expression by the histone demethylase JMJD1A is essential for prostate cancer cell growth and survival. Oncogene. 2016;35:2441-52 pubmed publisher
Hermanova I, Arruabarrena Aristorena A, Valis K, Nůsková H, Alberich Jorda M, Fiser K, et al. Pharmacological inhibition of fatty-acid oxidation synergistically enhances the effect of l-asparaginase in childhood ALL cells. Leukemia. 2016;30:209-18 pubmed publisher
product information
SKU :
9402S
Product-Name :
c-Myc Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Pg
Applications :
Chromatin Immunoprecipitation
Product-Category :
Apoptosis
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
57 to 70
Host :
Rabbit
Target :
Myc
Primary-Protein :
Myc
Alt-Names :
BHLHE39,Class E basic helix-loop-helix protein 39,MRTL,MYC,Myc proto-oncogene protein,Proto-oncogene c-Myc,Transcription factor p64,avian myelocytomatosis viral oncogene homolog,c-Myc,myc-related translation/localization regulatory factor,v-myc avian myelocytomatosis viral oncogene homolog,v-myc myelocytomatosis viral oncogene homolog (avian)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.