product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Rab7 (D95F2) XP® Rabbit mAb
catalog :
9367S
quantity :
100 ul
price :
260 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 24
Published Application/Species/DilutionReference
  • flow cytometry; mouse; fig 1
  • immunocytochemistry (knockout validation); mouse; fig 1
  • western blot (knockout validation); mouse; fig 1
Roy S, Stevens M, So L, Edinger A. Reciprocal effects of rab7 deletion in activated and neglected T cells. Autophagy. 2013;9:1009-23 pubmed publisher
  • western blot (knockdown validation); human; fig 4
Nonnenmacher M, Cintrat J, Gillet D, Weber T. Syntaxin 5-dependent retrograde transport to the trans-Golgi network is required for adeno-associated virus transduction. J Virol. 2015;89:1673-87 pubmed publisher
  • western blot; mouse; fig 2
He J, Johnson J, Monfregola J, Ramadass M, Pestonjamasp K, Napolitano G, et al. Munc13-4 interacts with syntaxin 7 and regulates late endosomal maturation, endosomal signaling, and TLR9-initiated cellular responses. Mol Biol Cell. 2016;27:572-87 pubmed publisher
  • western blot; human; 1:1000; fig 2
Gschweitl M, Ulbricht A, Barnes C, Enchev R, Stoffel-Studer I, Meyer-Schaller N, et al. A SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at endosomes. elife. 2016;5:e13841 pubmed publisher
  • immunocytochemistry; human; fig 4
Kajiho H, Kajiho Y, Frittoli E, Confalonieri S, Bertalot G, Viale G, et al. RAB2A controls MT1-MMP endocytic and E-cadherin polarized Golgi trafficking to promote invasive breast cancer programs. EMBO Rep. 2016;17:1061-80 pubmed publisher
  • immunocytochemistry; human; 1:50
Ketel K, Krauss M, Nicot A, Puchkov D, Wieffer M, Müller R, et al. A phosphoinositide conversion mechanism for exit from endosomes. Nature. 2016;529:408-12 pubmed publisher
  • immunocytochemistry; mouse; 1:100; fig 1
Marquer C, Tian H, Yi J, Bastien J, Dall'Armi C, Yang-Klingler Y, et al. Arf6 controls retromer traffic and intracellular cholesterol distribution via a phosphoinositide-based mechanism. Nat Commun. 2016;7:11919 pubmed publisher
  • immunocytochemistry; mouse; fig 2
Boothe T, Lim G, Cen H, Skovsø S, Piske M, Li S, et al. Inter-domain tagging implicates caveolin-1 in insulin receptor trafficking and Erk signaling bias in pancreatic beta-cells. Mol Metab. 2016;5:366-78 pubmed publisher
  • immunocytochemistry; human; 1:100
Bunse L, Schumacher T, Sahm F, Pusch S, Oezen I, Rauschenbach K, et al. Proximity ligation assay evaluates IDH1R132H presentation in gliomas. J Clin Invest. 2015;125:593-606 pubmed publisher
  • western blot; human; 1:2000; fig 7
  • immunocytochemistry; human; 1:100; fig 7
Zhao Z, Sagare A, Ma Q, Halliday M, Kong P, Kisler K, et al. Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance. Nat Neurosci. 2015;18:978-87 pubmed publisher
  • western blot; rat; 1:1000
Chichger H, Braza J, Duong H, Stark M, Harrington E. Neovascularization in the pulmonary endothelium is regulated by the endosome: Rab4-mediated trafficking and p18-dependent signaling. Am J Physiol Lung Cell Mol Physiol. 2015;309:L700-9 pubmed publisher
  • western blot; mouse; fig 5b
Kizuka Y, Kitazume S, Fujinawa R, Saito T, Iwata N, Saido T, et al. An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease. EMBO Mol Med. 2015;7:175-89 pubmed publisher
  • immunocytochemistry; mouse
Lalioti V, Ilari A, O'Connell D, Poser E, Sandoval I, Colotti G. Sorcin links calcium signaling to vesicle trafficking, regulates Polo-like kinase 1 and is necessary for mitosis. PLoS ONE. 2014;9:e85438 pubmed publisher
  • immunocytochemistry; mouse
Rai S, Tanaka H, Suzuki M, Ogoh H, Taniguchi Y, Morita Y, et al. Clathrin assembly protein CALM plays a critical role in KIT signaling by regulating its cellular transport from early to late endosomes in hematopoietic cells. PLoS ONE. 2014;9:e109441 pubmed publisher
  • immunocytochemistry; human
Lou J, Low-Nam S, Kerkvliet J, Hoppe A. Delivery of CSF-1R to the lumen of macropinosomes promotes its destruction in macrophages. J Cell Sci. 2014;127:5228-39 pubmed publisher
Martin-Antonio B, Najjar A, Robinson S, Chew C, Li S, Yvon E, et al. Transmissible cytotoxicity of multiple myeloma cells by cord blood-derived NK cells is mediated by vesicle trafficking. Cell Death Differ. 2015;22:96-107 pubmed publisher
Hwang S, Disatnik M, Mochly-Rosen D. Impaired GAPDH-induced mitophagy contributes to the pathology of Huntington's disease. EMBO Mol Med. 2015;7:1307-26 pubmed publisher
Nakamura K, Yamanouchi K, Nishihara M. Secreted protein acidic and rich in cysteine internalization and its age-related alterations in skeletal muscle progenitor cells. Aging Cell. 2014;13:175-84 pubmed publisher
Nada S, Mori S, Takahashi Y, Okada M. p18/LAMTOR1: a late endosome/lysosome-specific anchor protein for the mTORC1/MAPK signaling pathway. Methods Enzymol. 2014;535:249-63 pubmed publisher
Lee H, Lee J, Park M, Hong Y, Marti H, Kim H, et al. Pathological roles of the VEGF/SphK pathway in Niemann-Pick type C neurons. Nat Commun. 2014;5:5514 pubmed publisher
Cogli L, Progida C, Thomas C, Spencer-Dene B, Donno C, Schiavo G, et al. Charcot-Marie-Tooth type 2B disease-causing RAB7A mutant proteins show altered interaction with the neuronal intermediate filament peripherin. Acta Neuropathol. 2013;125:257-72 pubmed publisher
Fujita H, Kitawaki T, Sato T, Maeda T, Kamihira S, Takaori-Kondo A, et al. The tyrosine kinase inhibitor dasatinib suppresses cytokine production by plasmacytoid dendritic cells by targeting endosomal transport of CpG DNA. Eur J Immunol. 2013;43:93-103 pubmed publisher
Gupton S, Riquelme D, Hughes-Alford S, Tadros J, Rudina S, Hynes R, et al. Mena binds α5 integrin directly and modulates α5β1 function. J Cell Biol. 2012;198:657-76 pubmed publisher
Swaminathan G, Cartwright C. Rack1 promotes epithelial cell-cell adhesion by regulating E-cadherin endocytosis. Oncogene. 2012;31:376-89 pubmed publisher
product information
SKU :
9367S
Product-Name :
Rab7 (D95F2) XP® Rabbit mAb
Size :
100 ul
Price-(USD) :
260 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Protein Folding and Trafficking
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
23
Host :
Rabbit
Target :
Rab7
Primary-Protein :
Rab7
Alt-Names :
FLJ20819,PRO2706,RAB7,RAB7, member RAS oncogene family,RAB7A,RAB7A, member RAS oncogene family,Ras-associated protein RAB7,Ras-related protein Rab-7a
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.