Phospho-p90RSK (Thr359/Ser363) Antibody | Cell Signaling Technology 9344 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Phospho-p90RSK (Thr359/Ser363) Antibody

catalog :

9344

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, reverse phase protein lysate microarray

more info or order :

Cell Signaling Technology product webpage

citations: 17

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:1000; loading ...	Hamilton W, Mosesson Y, Monteiro R, Emdal K, Knudsen T, Francavilla C, et al. Dynamic lineage priming is driven via direct enhancer regulation by ERK. Nature. 2019;: pubmed publisher
western blot; human; loading ...; fig s2f	Lee C, Moon S, Jeong J, Lee S, Lee M, Yoo S, et al. Kaempferol targeting on the fibroblast growth factor receptor 3-ribosomal S6 kinase 2 signaling axis prevents the development of rheumatoid arthritis. Cell Death Dis. 2018;9:401 pubmed publisher
western blot; mouse; loading ...; fig 4a	Sutavani R, Phair I, Barker R, McFarlane A, Shpiro N, Lang S, et al. Differential control of Toll-like receptor 4-induced interleukin-10 induction in macrophages and B cells reveals a role for p90 ribosomal S6 kinases. J Biol Chem. 2018;293:2302-2317 pubmed publisher
reverse phase protein lysate microarray; human; loading ...; fig st6	Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
western blot; mouse; loading ...; fig 2a	Kidger A, Rushworth L, Stellzig J, Davidson J, Bryant C, Bayley C, et al. Dual-specificity phosphatase 5 controls the localized inhibition, propagation, and transforming potential of ERK signaling. Proc Natl Acad Sci U S A. 2017;114:E317-E326 pubmed publisher
western blot; human; loading ...; fig S8	Piasecka D, Kitowska K, Czaplinska D, Mieczkowski K, Mieszkowska M, Turczyk L, et al. Fibroblast growth factor signalling induces loss of progesterone receptor in breast cancer cells. Oncotarget. 2016;7:86011-86025 pubmed publisher
western blot; human; 1:1000; loading ...; fig 1d	Krepler C, Xiao M, Samanta M, Vultur A, Chen H, Brafford P, et al. Targeting Notch enhances the efficacy of ERK inhibitors in BRAF-V600E melanoma. Oncotarget. 2016;7:71211-71222 pubmed publisher
western blot; human; loading ...; fig 8c	Zhou B, Ritt D, Morrison D, Der C, Cox A. Protein Kinase CK2? Maintains Extracellular Signal-regulated Kinase (ERK) Activity in a CK2? Kinase-independent Manner to Promote Resistance to Inhibitors of RAF and MEK but Not ERK in BRAF Mutant Melanoma. J Biol Chem. 2016;291:17804-15 pubmed publisher
western blot; mouse; fig 3	de Jong P, Taniguchi K, Harris A, Bertin S, Takahashi N, Duong J, et al. ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogation. Nat Commun. 2016;7:11551 pubmed publisher
western blot; human	Czaplinska D, Turczyk L, Grudowska A, Mieszkowska M, Lipinska A, Skladanowski A, et al. Phosphorylation of RSK2 at Tyr529 by FGFR2-p38 enhances human mammary epithelial cells migration. Biochim Biophys Acta. 2014;1843:2461-70 pubmed publisher
western blot; human	Chang P, Hung C, Wang S, Tsai P, Shih Y, Chen L, et al. Identification and characterization of two novel spliced genes located in the orf47-orf46-orf45 gene locus of Kaposi's sarcoma-associated herpesvirus. J Virol. 2014;88:10092-109 pubmed publisher
immunohistochemistry - frozen section; rat; 1:250 western blot; rat; 1:1000	Cheng C, Lin J, Su S, Tang N, Kao S, Hsieh C. Electroacupuncture-like stimulation at Baihui and Dazhui acupoints exerts neuroprotective effects through activation of the brain-derived neurotrophic factor-mediated MEK1/2/ERK1/2/p90RSK/bad signaling pathway in mild transient focal cerebral ischemi. BMC Complement Altern Med. 2014;14:92 pubmed publisher
western blot; human	Garcia Murillas I, Sharpe R, Pearson A, Campbell J, Natrajan R, Ashworth A, et al. An siRNA screen identifies the GNAS locus as a driver in 20q amplified breast cancer. Oncogene. 2014;33:2478-86 pubmed publisher
immunohistochemistry - paraffin section; mouse	Maeda Y, Fukushima K, Omichi R, Kariya S, Nishizaki K. Time courses of changes in phospho- and total- MAP kinases in the cochlea after intense noise exposure. PLoS ONE. 2013;8:e58775 pubmed publisher
	Lagares Tena L, GarcÃa MonclÃºs S, LÃ³pez Alemany R, Almacellas Rabaiget O, Huertas MartÃnez J, SÃ¡inz Jaspeado M, et al. Caveolin-1 promotes Ewing sarcoma metastasis regulating MMP-9 expression through MAPK/ERK pathway. Oncotarget. 2016;7:56889-56903 pubmed publisher
	Polak A, Kiliszek P, Sewastianik T, Szydłowski M, Jabłońska E, Białopiotrowicz E, et al. MEK Inhibition Sensitizes Precursor B-Cell Acute Lymphoblastic Leukemia (B-ALL) Cells to Dexamethasone through Modulation of mTOR Activity and Stimulation of Autophagy. PLoS ONE. 2016;11:e0155893 pubmed publisher
	Franks H, Wang Q, Lax S, Collins M, Escors D, Patel P, et al. Novel function for the p38-MK2 signaling pathway in circulating CD1c+ (BDCA-1+) myeloid dendritic cells from healthy donors and advanced cancer patients; inhibition of p38 enhances IL-12 whilst suppressing IL-10. Int J Cancer. 2014;134:575-86 pubmed publisher

product information

SKU :

9344S

Product-Name :

Phospho-p90RSK (Thr359/Ser363) Antibody

Size :

100 ul

Price-(USD) :

274 USD

Species-x-Reactivity :

H, M, R, Mk

Applications :

Immunoprecipitation

Product-Category :

MAP Kinase Signaling

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Polyclonal Antibody

MW :

Host :

Rabbit

Target :

RSK1 (Thr359/Ser363) phosphate/RSK3 (Thr356/Ser360) phosphate

more info or order :

Cell Signaling Technology product webpage