product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
GSK-3α Antibody
catalog :
9338
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, western blot knockout validation
more info or order :
Cell Signaling Technology product webpage
citations: 11
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; fig 1
Khan K, Dô F, Marineau A, Doyon P, Clément J, Woodgett J, et al. Fine-Tuning of the RIG-I-Like Receptor/Interferon Regulatory Factor 3-Dependent Antiviral Innate Immune Response by the Glycogen Synthase Kinase 3/β-Catenin Pathway. Mol Cell Biol. 2015;35:3029-43 pubmed publisher
  • western blot knockout validation; mouse; 1:1000; fig s1
Zhou J, Freeman T, Ahmad F, Shang X, Mangano E, Gao E, et al. GSK-3? is a central regulator of age-related pathologies in mice. J Clin Invest. 2013;123:1821-32 pubmed publisher
  • western blot; human; loading ...; fig s2
Shuang W, Hou L, Zhu Y, Li Q, Hu W. Mcl-1 stabilization confers resistance to taxol in human gastric cancer. Oncotarget. 2017;8:82981-82990 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig s1c
Zhou A, Lin K, Zhang S, Chen Y, Zhang N, Xue J, et al. Nuclear GSK3? promotes tumorigenesis by phosphorylating KDM1A and inducing its deubiquitylation by USP22. Nat Cell Biol. 2016;18:954-966 pubmed publisher
  • western blot; mouse; fig 2
Malanga D, Belmonte S, Colelli F, Scarfò M, De Marco C, Oliveira D, et al. AKT1E¹⁷K Is Oncogenic in Mouse Lung and Cooperates with Chemical Carcinogens in Inducing Lung Cancer. PLoS ONE. 2016;11:e0147334 pubmed publisher
  • western blot; mouse; 1:1000
Angliker N, Burri M, Zaichuk M, Fritschy J, Rüegg M. mTORC1 and mTORC2 have largely distinct functions in Purkinje cells. Eur J Neurosci. 2015;42:2595-612 pubmed publisher
Maurin H, Lechat B, Dewachter I, Ris L, Louis J, Borghgraef P, et al. Neurological characterization of mice deficient in GSK3? highlight pleiotropic physiological functions in cognition and pathological activity as Tau kinase. Mol Brain. 2013;6:27 pubmed publisher
Biensø R, Ringholm S, Kiilerich K, Aachmann Andersen N, Krogh Madsen R, Guerra B, et al. GLUT4 and glycogen synthase are key players in bed rest-induced insulin resistance. Diabetes. 2012;61:1090-9 pubmed publisher
Perez Costas E, Gandy J, Melendez Ferro M, Roberts R, Bijur G. Light and electron microscopy study of glycogen synthase kinase-3beta in the mouse brain. PLoS ONE. 2010;5:e8911 pubmed publisher
Wu M, Katta A, Gadde M, Liu H, Kakarla S, Fannin J, et al. Aging-associated dysfunction of Akt/protein kinase B: S-nitrosylation and acetaminophen intervention. PLoS ONE. 2009;4:e6430 pubmed publisher
An J, Yang D, Xu Q, Zhang S, Huo Y, Shang Z, et al. DNA-dependent protein kinase catalytic subunit modulates the stability of c-Myc oncoprotein. Mol Cancer. 2008;7:32 pubmed publisher
product information
SKU :
9338S
Product-Name :
GSK-3α Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Western blot
Product-Category :
PI3K / Akt Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
51
Host :
Rabbit
Target :
GSK3-alpha
Primary-Protein :
GSK3A
Alt-Names :
DKFZp686D0638,GSK-3 alpha,GSK3A,Glycogen synthase kinase-3 alpha,glycogen synthase kinase 3 alpha
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.