| Published Application/Species/Dilution | Reference |
|---|
- western blot; mouse; fig s2
| Kim S, Choi K, Cho S, Yun S, Jeon J, Koh Y, et al. Fisetin stimulates autophagic degradation of phosphorylated tau via the activation of TFEB and Nrf2 transcription factors. Sci Rep. 2016;6:24933 pubmed publisher |
- western blot; mouse; 1:1000; fig 6
| Dinger K, Kasper P, Hucklenbruch-Rother E, Vohlen C, Jobst E, Janoschek R, et al. Early-onset obesity dysregulates pulmonary adipocytokine/insulin signaling and induces asthma-like disease in mice. Sci Rep. 2016;6:24168 pubmed publisher |
- western blot; mouse; 1:1000; tbl 1
| Guillot F, Kemppainen S, Lavasseur G, Miettinen P, Laroche S, Tanila H, et al. Brain-Specific Basal and Novelty-Induced Alternations in PI3K-Akt and MAPK/ERK Signaling in a Middle-Aged AβPP/PS1 Mouse Model of Alzheimer's Disease. J Alzheimers Dis. 2016;51:1157-73 pubmed publisher |
- western blot; human; fig 6
| Huang Y, Lin C, Liao H, Liu C, Chen Y, Chiu W, et al. Cholesterol overload induces apoptosis in SH-SY5Y human neuroblastoma cells through the up regulation of flotillin-2 in the lipid raft and the activation of BDNF/Trkb signaling. Neuroscience. 2016;328:201-9 pubmed publisher |
- western blot; human; 1:1000; fig 4
| Hu W, Xiao L, Cao C, Hua S, Wu D. UBE2T promotes nasopharyngeal carcinoma cell proliferation, invasion, and metastasis by activating the AKT/GSK3β/β-catenin pathway. Oncotarget. 2016;7:15161-72 pubmed publisher |
- western blot; human; fig 3
| Kuang J, Li L, Guo L, Su Y, Wang Y, Xu Y, et al. RNF8 promotes epithelial-mesenchymal transition of breast cancer cells. J Exp Clin Cancer Res. 2016;35:88 pubmed publisher |
- western blot; mouse; 1:1000
| Kim K, Qiang L, Hayden M, Sparling D, Purcell N, Pajvani U. mTORC1-independent Raptor prevents hepatic steatosis by stabilizing PHLPP2. Nat Commun. 2016;7:10255 pubmed publisher |
- western blot; human; 1:200; fig st1
| Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher |
- western blot; mouse; fig 6
| Hsu Y, Chang P, Ho C, Huang Y, Shih Y, Wang C, et al. Protective effects of miR-29a on diabetic glomerular dysfunction by modulation of DKK1/Wnt/β-catenin signaling. Sci Rep. 2016;6:30575 pubmed publisher |
- western blot; mouse; 1:1000; fig 6
| Herring A, Münster Y, Akkaya T, Moghaddam S, Deinsberger K, Meyer J, et al. Kallikrein-8 inhibition attenuates Alzheimer's pathology in mice. Alzheimers Dement. 2016;: pubmed publisher |
- western blot; human; 1:750; fig 2
| Vétillard A, Jonchère B, Moreau M, Toutain B, Henry C, Fontanel S, et al. Akt inhibition improves irinotecan treatment and prevents cell emergence by switching the senescence response to apoptosis. Oncotarget. 2015;6:43342-62 pubmed publisher |
- immunohistochemistry; mouse
- western blot; mouse
| Tan X, Xue Y, Ma T, Wang X, Li J, Lan L, et al. Partial eNOS deficiency causes spontaneous thrombotic cerebral infarction, amyloid angiopathy and cognitive impairment. Mol Neurodegener. 2015;10:24 pubmed publisher |
| Nakazawa H, Yamada M, Tanaka T, Kramer J, Yu Y, Fischman A, et al. Role of protein farnesylation in burn-induced metabolic derangements and insulin resistance in mouse skeletal muscle. PLoS ONE. 2015;10:e0116633 pubmed publisher |
- western blot; mouse; 1:1000
| Seo M, Lee C, Cho H, You Y, Lee B, Lee J, et al. Effects of antipsychotic drugs on the expression of synapse-associated proteins in the frontal cortex of rats subjected to immobilization stress. Psychiatry Res. 2015;229:968-74 pubmed publisher |
- western blot; mouse; fig s9
| Hu X, Garcia C, Fazli L, Gleave M, Vitek M, Jansen M, et al. Inhibition of Pten deficient Castration Resistant Prostate Cancer by Targeting of the SET - PP2A Signaling axis. Sci Rep. 2015;5:15182 pubmed publisher |
- other; mouse; 1:1000; fig s1
| Chiang C, Uzoma I, Lane D, Memisevic V, Alem F, Yao K, et al. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Front Microbiol. 2015;6:683 pubmed publisher |
- western blot; human; 1:1000
| Li F, Song N, Tombran-Tink J, Niyibizi C. Pigment epithelium derived factor suppresses expression of Sost/Sclerostin by osteocytes: implication for its role in bone matrix mineralization. J Cell Physiol. 2015;230:1243-9 pubmed publisher |
- western blot; mouse; fig 5
| Jackson B, Ivanova I, Dagnino L. An ELMO2-RhoG-ILK network modulates microtubule dynamics. Mol Biol Cell. 2015;26:2712-25 pubmed publisher |
- western blot; mouse; 1:2000
| Gallo D, Gesmundo I, Trovato L, Pera G, Gargantini E, Minetto M, et al. GH-Releasing Hormone Promotes Survival and Prevents TNF-α-Induced Apoptosis and Atrophy in C2C12 Myotubes. Endocrinology. 2015;156:3239-52 pubmed publisher |
- western blot; human; fig 1
| Hausmann S, Brandt E, Köchel C, Einsele H, Bargou R, Seggewiss-Bernhardt R, et al. Loss of serum and glucocorticoid-regulated kinase 3 (SGK3) does not affect proliferation and survival of multiple myeloma cell lines. PLoS ONE. 2015;10:e0122689 pubmed publisher |
- western blot; rat; 1:1000; fig 5
| Nagaoka K, Matoba T, Mao Y, Nakano Y, Ikeda G, Egusa S, et al. A New Therapeutic Modality for Acute Myocardial Infarction: Nanoparticle-Mediated Delivery of Pitavastatin Induces Cardioprotection from Ischemia-Reperfusion Injury via Activation of PI3K/Akt Pathway and Anti-Inflammation in a Rat Model. PLoS ONE. 2015;10:e0132451 pubmed publisher |
- western blot; human; 1:1000; fig 6
| Martínez-Revollar G, Garay E, Martín-Tapia D, Nava P, Huerta M, Lopez-Bayghen E, et al. Heterogeneity between triple negative breast cancer cells due to differential activation of Wnt and PI3K/AKT pathways. Exp Cell Res. 2015;339:67-80 pubmed publisher |
| Kauko O, Laajala T, Jumppanen M, Hintsanen P, Suni V, Haapaniemi P, et al. Label-free quantitative phosphoproteomics with novel pairwise abundance normalization reveals synergistic RAS and CIP2A signaling. Sci Rep. 2015;5:13099 pubmed publisher |
- western blot; human; fig 6
| Hotokezaka Y, Katayama I, van Leyen K, Nakamura T. GSK-3β-dependent downregulation of γ-taxilin and αNAC merge to regulate ER stress responses. Cell Death Dis. 2015;6:e1719 pubmed publisher |
- western blot; human; 1:1000; fig s5
| Leve F, Peres-Moreira R, Binato R, Abdelhay E, Morgado-Diaz J. LPA Induces Colon Cancer Cell Proliferation through a Cooperation between the ROCK and STAT-3 Pathways. PLoS ONE. 2015;10:e0139094 pubmed publisher |
- western blot; human; fig s2b
| Gasser J, Inuzuka H, Lau A, Wei W, Beroukhim R, Toker A. SGK3 mediates INPP4B-dependent PI3K signaling in breast cancer. Mol Cell. 2014;56:595-607 pubmed publisher |
- western blot; human; 1:1000; fig 1
| Yu P, Laird A, Du X, Wu J, Won K, Yamaguchi K, et al. Characterization of the activity of the PI3K/mTOR inhibitor XL765 (SAR245409) in tumor models with diverse genetic alterations affecting the PI3K pathway. Mol Cancer Ther. 2014;13:1078-91 pubmed publisher |
| Jin G, Liu B, You Z, Bambakidis T, Dekker S, Maxwell J, et al. Development of a novel neuroprotective strategy: combined treatment with hypothermia and valproic acid improves survival in hypoxic hippocampal cells. Surgery. 2014;156:221-8 pubmed publisher |
| Ito Y, Hart J, Ueno L, Vogt P. Oncogenic activity of the regulatory subunit p85β of phosphatidylinositol 3-kinase (PI3K). Proc Natl Acad Sci U S A. 2014;111:16826-9 pubmed publisher |
| Kubota H, Noguchi R, Toyoshima Y, Ozaki Y, Uda S, Watanabe K, et al. Temporal coding of insulin action through multiplexing of the AKT pathway. Mol Cell. 2012;46:820-32 pubmed publisher |
| Fujita H, Utsumi T, Muranaka S, Ogino T, Yano H, Akiyama J, et al. Involvement of Ras/extracellular signal-regulated kinase, but not Akt pathway in risedronate-induced apoptosis of U937 cells and its suppression by cytochalasin B. Biochem Pharmacol. 2005;69:1773-84 pubmed |
| Hirai S, Cui D, Miyata T, Ogawa M, Kiyonari H, Suda Y, et al. The c-Jun N-terminal kinase activator dual leucine zipper kinase regulates axon growth and neuronal migration in the developing cerebral cortex. J Neurosci. 2006;26:11992-2002 pubmed |
| Guertin D, Stevens D, Saitoh M, Kinkel S, Crosby K, Sheen J, et al. mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice. Cancer Cell. 2009;15:148-59 pubmed publisher |
