| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; mouse; loading ...; fig 4e
| Li J, Chiu J, Ramanjulu M, Blass B, Pratico D. A pharmacological chaperone improves memory by reducing Aβ and tau neuropathology in a mouse model with plaques and tangles. Mol Neurodegener. 2020;15:1 pubmed publisher |
- western blot; mouse; loading ...; fig 3b
| Uddin G, Zhang L, Shah S, Fukushima A, Wagg C, Gopal K, et al. Impaired branched chain amino acid oxidation contributes to cardiac insulin resistance in heart failure. Cardiovasc Diabetol. 2019;18:86 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 3i
| Martins V, Dent J, Svensson K, Tahvilian S, Begur M, Lakkaraju S, et al. Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity. Am J Physiol Endocrinol Metab. 2019;: pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 2d
- western blot; mouse; 1:1000; loading ...; fig 2d, 4g
| Shen B, Vardy K, Hughes P, Tasdogan A, Zhao Z, Yue R, et al. Integrin alpha11 is an Osteolectin receptor and is required for the maintenance of adult skeletal bone mass. elife. 2019;8: pubmed publisher |
- western blot; rat; 1:1000; loading ...; fig 3b
| Zhou X, Zhang R, Zou Z, Shen X, Xie T, Xu C, et al. Hypoglycaemic effects of glimepiride in sulfonylurea receptor 1 deficient rat. Br J Pharmacol. 2019;176:478-490 pubmed publisher |
- other; human; loading ...; fig 4c
| Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher |
- western blot; human; loading ...; fig s2a
| Sutavani R, Phair I, Barker R, McFarlane A, Shpiro N, Lang S, et al. Differential control of Toll-like receptor 4-induced interleukin-10 induction in macrophages and B cells reveals a role for p90 ribosomal S6 kinases. J Biol Chem. 2018;293:2302-2317 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 5c
| Krag T, Ruiz Ruiz C, Vissing J. Glycogen Synthesis in Glycogenin 1-Deficient Patients: A Role for Glycogenin 2 in Muscle. J Clin Endocrinol Metab. 2017;102:2690-2700 pubmed publisher |
- reverse phase protein lysate microarray; human; loading ...; fig st6
| Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher |
- western blot; mouse; loading ...; fig 7a
| Dong Q, Li J, Wu Q, Zhao N, Qian C, Ding D, et al. Blockage of transient receptor potential vanilloid 4 alleviates myocardial ischemia/reperfusion injury in mice. Sci Rep. 2017;7:42678 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 4o
| Wu M, Chen W, Lu Y, Zhu G, Hao L, Li Y. Gα13 negatively controls osteoclastogenesis through inhibition of the Akt-GSK3β-NFATc1 signalling pathway. Nat Commun. 2017;8:13700 pubmed publisher |
- western blot; human; 1:100; loading ...; fig 3b
| Granato M, Rizzello C, Gilardini Montani M, Cuomo L, Vitillo M, Santarelli R, et al. Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways. J Nutr Biochem. 2017;41:124-136 pubmed publisher |
- western blot; human; 1:1000; loading ...
| Merckx E, Albertini G, Paterka M, Jensen C, Albrecht P, Dietrich M, et al. Absence of system xc- on immune cells invading the central nervous system alleviates experimental autoimmune encephalitis. J Neuroinflammation. 2017;14:9 pubmed publisher |
- western blot; human; loading ...
| Hill S, Nesser N, Johnson Camacho K, Jeffress M, Johnson A, Boniface C, et al. Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling. Cell Syst. 2017;4:73-83.e10 pubmed publisher |
- western blot; human; loading ...; fig 5a
| Li Y, Buijs Gladdines J, Canté Barrett K, Stubbs A, Vroegindeweij E, Smits W, et al. IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study. PLoS Med. 2016;13:e1002200 pubmed publisher |
- western blot; human; loading ...; fig s1
| Tai Y, Tung L, Lin Y, Lu P, Chu P, Wang M, et al. Grb7 Protein Stability Modulated by Pin1 in Association with Cell Cycle Progression. PLoS ONE. 2016;11:e0163617 pubmed publisher |
- western blot; mouse; loading ...; fig 1d
| Diez H, Benitez M, Fernandez S, Torres Aleman I, Garrido J, Wandosell F. Class I PI3-kinase or Akt inhibition do not impair axonal polarization, but slow down axonal elongation. Biochim Biophys Acta. 2016;1863:2574-2583 pubmed publisher |
- western blot; mouse; fig 1
| Hey F, Giblett S, Forrest S, Herbert C, Pritchard C. Phosphorylations of Serines 21/9 in Glycogen Synthase Kinase 3α/β Are Not Required for Cell Lineage Commitment or WNT Signaling in the Normal Mouse Intestine. PLoS ONE. 2016;11:e0156877 pubmed publisher |
- western blot; mouse; loading ...; fig 1a
| Krag T, Pinós T, Nielsen T, Duran J, GarcÃa Rocha M, Andreu A, et al. Differential glucose metabolism in mice and humans affected by McArdle disease. Am J Physiol Regul Integr Comp Physiol. 2016;311:R307-14 pubmed publisher |
- immunohistochemistry; mouse; 1:200; fig 5d
| Itoh Y, Higuchi M, Oishi K, Kishi Y, Okazaki T, Sakai H, et al. PDK1-Akt pathway regulates radial neuronal migration and microtubules in the developing mouse neocortex. Proc Natl Acad Sci U S A. 2016;113:E2955-64 pubmed publisher |
- western blot; mouse; 1:1000; fig 4
| Plucińska K, Dekeryte R, Koss D, Shearer K, Mody N, Whitfield P, et al. Neuronal human BACE1 knockin induces systemic diabetes in mice. Diabetologia. 2016;59:1513-1523 pubmed publisher |
- western blot; human; fig 4
| Kurbatskaya K, Phillips E, Croft C, Dentoni G, Hughes M, Wade M, et al. Upregulation of calpain activity precedes tau phosphorylation and loss of synaptic proteins in Alzheimer's disease brain. Acta Neuropathol Commun. 2016;4:34 pubmed publisher |
- western blot; human; fig 6
| Lee J, Kim H, Rho S, Lee S. eIF3f reduces tumor growth by directly interrupting clusterin with anti-apoptotic property in cancer cells. Oncotarget. 2016;7:18541-57 pubmed publisher |
- western blot; human; 1:3000; loading ...; tbl s2
| Santio N, Salmela M, Arola H, Eerola S, Heino J, Rainio E, et al. The PIM1 kinase promotes prostate cancer cell migration and adhesion via multiple signalling pathways. Exp Cell Res. 2016;342:113-24 pubmed publisher |
- western blot; mouse; fig 3
| Gong Q, Hu Z, Zhang F, Cui A, Chen X, Jiang H, et al. Fibroblast growth factor 21 improves hepatic insulin sensitivity by inhibiting mammalian target of rapamycin complex 1 in mice. Hepatology. 2016;64:425-38 pubmed publisher |
- western blot; mouse; fig 5
| Hu H, Wang H, Xiao Y, Jin J, Chang J, Zou Q, et al. Otud7b facilitates T cell activation and inflammatory responses by regulating Zap70 ubiquitination. J Exp Med. 2016;213:399-414 pubmed publisher |
- western blot; mouse; loading ...; fig 7e
| Lakshmipathi J, Alvarez Perez J, Rosselot C, Casinelli G, Stamateris R, Rausell Palamos F, et al. PKCζ Is Essential for Pancreatic β-Cell Replication During Insulin Resistance by Regulating mTOR and Cyclin-D2. Diabetes. 2016;65:1283-96 pubmed publisher |
- western blot; mouse; fig 2
| Malanga D, Belmonte S, Colelli F, Scarfò M, De Marco C, Oliveira D, et al. AKT1E¹⁷K Is Oncogenic in Mouse Lung and Cooperates with Chemical Carcinogens in Inducing Lung Cancer. PLoS ONE. 2016;11:e0147334 pubmed publisher |
- western blot; human; fig 4
| Sakurikar N, Thompson R, Montano R, Eastman A. A subset of cancer cell lines is acutely sensitive to the Chk1 inhibitor MK-8776 as monotherapy due to CDK2 activation in S phase. Oncotarget. 2016;7:1380-94 pubmed publisher |
- western blot; mouse; fig 1
| Kenney J, Genheden M, Moon K, Wang X, Foster L, Proud C. Eukaryotic elongation factor 2 kinase regulates the synthesis of microtubule-related proteins in neurons. J Neurochem. 2016;136:276-84 pubmed publisher |
- western blot; mouse; fig 5
| Sabirzhanov B, Stoica B, Zhao Z, Loane D, Wu J, Dorsey S, et al. miR-711 upregulation induces neuronal cell death after traumatic brain injury. Cell Death Differ. 2016;23:654-68 pubmed publisher |
- western blot; human; loading ...; fig 4b
| Reuther C, Heinzle V, Spampatti M, Vlotides G, de Toni E, Spöttl G, et al. Cabozantinib and Tivantinib, but Not INC280, Induce Antiproliferative and Antimigratory Effects in Human Neuroendocrine Tumor Cells in vitro: Evidence for 'Off-Target' Effects Not Mediated by c-Met Inhibition. Neuroendocrinology. 2016;103:383-401 pubmed publisher |
- western blot; human; fig 4
| Urban B, Collard T, Eagle C, Southern S, Greenhough A, Hamdollah Zadeh M, et al. BCL-3 expression promotes colorectal tumorigenesis through activation of AKT signalling. Gut. 2016;65:1151-64 pubmed publisher |
| Moniz L, Surinova S, Ghazaly E, Velasco L, Haider S, Rodríguez Prados J, et al. Phosphoproteomic comparison of Pik3ca and Pten signalling identifies the nucleotidase NT5C as a novel AKT substrate. Sci Rep. 2017;7:39985 pubmed publisher |
| Zhang W, Wu M, Kim T, Jariwala R, Garvey W, Luo N, et al. Skeletal Muscle TRIB3 Mediates Glucose Toxicity in Diabetes and High- Fat Diet-Induced Insulin Resistance. Diabetes. 2016;65:2380-91 pubmed publisher |
