Published Application/Species/Dilution | Reference |
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- western blot; mouse; fig 3
| Kral J, Kuttke M, Schrottmaier W, Birnecker B, Warszawska J, Wernig C, et al. Sustained PI3K Activation exacerbates BLM-induced Lung Fibrosis via activation of pro-inflammatory and pro-fibrotic pathways. Sci Rep. 2016;6:23034 pubmed publisher
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- western blot; human; fig 2
| Katoh I, Fukunishi N, Fujimuro M, Kasai H, Moriishi K, Hata R, et al. Repression of Wnt/β-catenin response elements by p63 (TP63). Cell Cycle. 2016;15:699-710 pubmed publisher
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- immunohistochemistry; human; 1:100; fig 6
- western blot; human; fig 1
| Gao X, Feng J, He Y, Xu F, Fan X, Huang W, et al. hnRNPK inhibits GSK3β Ser9 phosphorylation, thereby stabilizing c-FLIP and contributes to TRAIL resistance in H1299 lung adenocarcinoma cells. Sci Rep. 2016;6:22999 pubmed publisher
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- western blot; mouse; fig s4
| Fagnocchi L, Cherubini A, Hatsuda H, Fasciani A, Mazzoleni S, Poli V, et al. A Myc-driven self-reinforcing regulatory network maintains mouse embryonic stem cell identity. Nat Commun. 2016;7:11903 pubmed publisher
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- western blot; human; fig 5
| Xi Z, Yao M, Li Y, Xie C, Holst J, Liu T, et al. Guttiferone K impedes cell cycle re-entry of quiescent prostate cancer cells via stabilization of FBXW7 and subsequent c-MYC degradation. Cell Death Dis. 2016;7:e2252 pubmed publisher
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- western blot; human; fig 4
| Luey B, May F. Insulin-like growth factors are essential to prevent anoikis in oestrogen-responsive breast cancer cells: importance of the type I IGF receptor and PI3-kinase/Akt pathway. Mol Cancer. 2016;15:8 pubmed publisher
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- western blot; human; 1:1000
| Gassen N, Hartmann J, Zannas A, Kretzschmar A, Zschocke J, Maccarrone G, et al. FKBP51 inhibits GSK3β and augments the effects of distinct psychotropic medications. Mol Psychiatry. 2016;21:277-89 pubmed publisher
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- western blot; human; fig 3
| Hansen N, Hjort L, Broholm C, Gillberg L, Schrölkamp M, Schultz H, et al. Metabolic and Transcriptional Changes in Cultured Muscle Stem Cells from Low Birth Weight Subjects. J Clin Endocrinol Metab. 2016;101:2254-64 pubmed publisher
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- western blot; mouse; 1:1000; fig 2
| Pan Y, Deng Y, Xie S, Wang Z, Wang Y, Ren J, et al. Altered Wnt Signaling Pathway in Cognitive Impairment Caused by Chronic Intermittent Hypoxia: Focus on Glycogen Synthase Kinase-3β and β-catenin. Chin Med J (Engl). 2016;129:838-45 pubmed publisher
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- western blot; human; fig 3
| Guinot A, Oeztuerk-Winder F, Ventura J. miR-17-92/p38α Dysregulation Enhances Wnt Signaling and Selects Lgr6+ Cancer Stem-like Cells during Lung Adenocarcinoma Progression. Cancer Res. 2016;76:4012-22 pubmed publisher
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- western blot; human; fig 4
| Li B, Sun J, Dong Z, Xue P, He X, Liao L, et al. GCN5 modulates osteogenic differentiation of periodontal ligament stem cells through DKK1 acetylation in inflammatory microenvironment. Sci Rep. 2016;6:26542 pubmed publisher
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- western blot; mouse; 1:500; fig s1
| Yin Y, Gao D, Wang Y, Wang Z, Wang X, Ye J, et al. Tau accumulation induces synaptic impairment and memory deficit by calcineurin-mediated inactivation of nuclear CaMKIV/CREB signaling. Proc Natl Acad Sci U S A. 2016;113:E3773-81 pubmed publisher
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- western blot; mouse; fig 3
| Diersch S, Wirth M, Schneeweis C, Jörs S, Geisler F, Siveke J, et al. Kras(G12D) induces EGFR-MYC cross signaling in murine primary pancreatic ductal epithelial cells. Oncogene. 2016;35:3880-6 pubmed publisher
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- western blot; human; 1:1000; tbl 1
| Oudart J, Doué M, Vautrin A, Brassart B, Sellier C, Dupont-Deshorgue A, et al. The anti-tumor NC1 domain of collagen XIX inhibits the FAK/ PI3K/Akt/mTOR signaling pathway through αvβ3 integrin interaction. Oncotarget. 2016;7:1516-28 pubmed publisher
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| Rizvi F, Mathur A, Krishna S, Siddiqi M, Kakkar P. Suppression in PHLPP2 induction by morin promotes Nrf2-regulated cellular defenses against oxidative injury to primary rat hepatocytes. Redox Biol. 2015;6:587-98 pubmed publisher
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- western blot; mouse; 1:1000
| Rodríguez-Seoane C, Ramos A, Korth C, Requena J. DISC1 regulates expression of the neurotrophin VGF through the PI3K/AKT/CREB pathway. J Neurochem. 2015;135:598-605 pubmed publisher
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- western blot; human; fig 1
| Yi Y, Kang H, Bae E, Oh S, Seong Y, Bae I. β-TrCP1 degradation is a novel action mechanism of PI3K/mTOR inhibitors in triple-negative breast cancer cells. Exp Mol Med. 2015;47:e143 pubmed publisher
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- western blot; mouse; fig 2
| Wang Y, Zhang Y, Hu W, Xie S, Gong C, Iqbal K, et al. Rapid alteration of protein phosphorylation during postmortem: implication in the study of protein phosphorylation. Sci Rep. 2015;5:15709 pubmed publisher
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| Fine J, Renner D, Forsberg A, Cameron R, Galick B, Le C, et al. Intranasal deferoxamine engages multiple pathways to decrease memory loss in the APP/PS1 model of amyloid accumulation. Neurosci Lett. 2015;584:362-7 pubmed publisher
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- western blot; human; 1:3000; fig 1c
- western blot; mouse; 1:3000; fig 1b
| Lee M, Jeong M, Lee H, Han H, Ko A, Hewitt S, et al. PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis. Nat Commun. 2015;6:7769 pubmed publisher
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- western blot; mouse
- western blot; rat
| Zeldich E, Chen C, Colvin T, Bove-Fenderson E, Liang J, Tucker Zhou T, et al. The neuroprotective effect of Klotho is mediated via regulation of members of the redox system. J Biol Chem. 2014;289:24700-15 pubmed publisher
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- immunocytochemistry; human; 1:300
- western blot; human
| Bastos L, de Marcondes P, de-Freitas-Junior J, Leve F, Mencalha A, de Souza W, et al. Progeny from irradiated colorectal cancer cells acquire an EMT-like phenotype and activate Wnt/β-catenin pathway. J Cell Biochem. 2014;115:2175-87 pubmed publisher
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| Katkoori V, Basson M, Bond V, Manne U, Bumpers H. Nef-M1, a peptide antagonist of CXCR4, inhibits tumor angiogenesis and epithelial‑to‑mesenchymal transition in colon and breast cancers. Oncotarget. 2015;6:27763-77 pubmed publisher
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| Guertin D, Stevens D, Saitoh M, Kinkel S, Crosby K, Sheen J, et al. mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice. Cancer Cell. 2009;15:148-59 pubmed publisher
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