| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; loading ...; fig 7b
| Zhao Y, Sun J, Li Y, Zhou X, Zhai W, Wu Y, et al. Tryptophan 2,3-dioxygenase 2 controls M2 macrophages polarization to promote esophageal squamous cell carcinoma progression via AKT/GSK3β/IL-8 signaling pathway. Acta Pharm Sin B. 2021;11:2835-2849 pubmed publisher |
- western blot; mouse; loading ...; fig 5b
| Liu Y, Li Y, Huang S, Li Y, Xia J, Jia J, et al. Liver-specific over-expression of Cripto-1 in transgenic mice promotes hepatocyte proliferation and deregulated expression of hepatocarcinogenesis-related genes and signaling pathways. Aging (Albany NY). 2021;13:21155-21190 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 6d
| Xu X, Lei Y, Chen L, Zhou H, Liu H, Jiang J, et al. Phosphorylation of NF-κBp65 drives inflammation-mediated hepatocellular carcinogenesis and is a novel therapeutic target. J Exp Clin Cancer Res. 2021;40:253 pubmed publisher |
- western blot; human; loading ...; fig s4a
| Mygland L, Brinch S, Strand M, Olsen P, Aizenshtadt A, Lund K, et al. Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines. iScience. 2021;24:102807 pubmed publisher |
- western blot; human; loading ...; fig 4b
| Gan G, Shi Z, Liu D, Zhang S, Zhu H, Wang Y, et al. 3-hydroxyanthranic acid increases the sensitivity of hepatocellular carcinoma to sorafenib by decreasing tumor cell stemness. Cell Death Discov. 2021;7:173 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 3b
| Sakai H, Kawakami H, Teramura T, Onodera Y, Somers E, Furuuchi K, et al. Folate receptor α increases chemotherapy resistance through stabilizing MDM2 in cooperation with PHB2 that is overcome by MORAb-202 in gastric cancer. Clin Transl Med. 2021;11:e454 pubmed publisher |
- western blot; mouse; loading ...; fig s2a
| Mou S, Zhou Z, Feng H, Zhang N, Lin Z, Aiyasiding X, et al. Liquiritin Attenuates Lipopolysaccharides-Induced Cardiomyocyte Injury via an AMP-Activated Protein Kinase-Dependent Signaling Pathway. Front Pharmacol. 2021;12:648688 pubmed publisher |
- western blot; rat; 1:200; loading ...; fig 5a
| Luo L, Wu J, Lin T, Lian G, Wang H, Gao G, et al. Influence of atorvastatin on metabolic pattern of rats with pulmonary hypertension. Aging (Albany NY). 2021;13:11954-11968 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 6b
| Gao S, Gao L, Wang S, Shi X, Yue C, Wei S, et al. ATF3 Suppresses Growth and Metastasis of Clear Cell Renal Cell Carcinoma by Deactivating EGFR/AKT/GSK3β/β-Catenin Signaling Pathway. Front Cell Dev Biol. 2021;9:618987 pubmed publisher |
- western blot; human; loading ...; fig 4c
| Yu W, Hua Y, Qiu H, Hao J, Zou K, Li Z, et al. PD-L1 promotes tumor growth and progression by activating WIP and β-catenin signaling pathways and predicts poor prognosis in lung cancer. Cell Death Dis. 2020;11:506 pubmed publisher |
- western blot; mouse; 1:500; loading ...; fig s2b
| Waaler J, Mygland L, Tveita A, Strand M, Solberg N, Olsen P, et al. Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models. Commun Biol. 2020;3:196 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 7c
- western blot; rat; 1:1000; loading ...; fig 8a
| Zhou L, Shao C, Xie Y, Wang N, Xu S, Luo B, et al. Gab1 mediates PDGF signaling and is essential to oligodendrocyte differentiation and CNS myelination. elife. 2020;9: pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 8b
| Liu P, Yao R, Shi H, Liu Y, Lian S, Yang Y, et al. Effects of Cold-inducible RNA-binding Protein (CIRP) on Liver Glycolysis during Acute Cold Exposure in C57BL/6 Mice. Int J Mol Sci. 2019;20: pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 5a
| Shi H, Yao R, Lian S, Liu P, Liu Y, Yang Y, et al. Regulating glycolysis, the TLR4 signal pathway and expression of RBM3 in mouse liver in response to acute cold exposure. Stress. 2019;22:366-376 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 2a
| Peng J, Liang S, Li L. sFRP1 exerts effects on gastric cancer cells through GSK3β/Rac1‑mediated restraint of TGFβ/Smad3 signaling. Oncol Rep. 2019;41:224-234 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 5c
| Ding Y, Li N, Dong B, Guo W, Wei H, Chen Q, et al. Chromatin remodeling ATPase BRG1 and PTEN are synthetic lethal in prostate cancer. J Clin Invest. 2019;129:759-773 pubmed publisher |
- western blot; human; loading ...; fig 7e
| Lionnard L, Duc P, Brennan M, Kueh A, Pal M, Guardia F, et al. TRIM17 and TRIM28 antagonistically regulate the ubiquitination and anti-apoptotic activity of BCL2A1. Cell Death Differ. 2019;26:902-917 pubmed publisher |
- western blot; mouse; loading ...; fig s7b
| Patra D, DeLassus E, Mueller J, Abou Ezzi G, Sandell L. Site-1 protease regulates skeletal stem cell population and osteogenic differentiation in mice. Biol Open. 2018;7: pubmed publisher |
- western blot; human; loading ...; fig 7b
| Zhao Z, Jia Q, Wu M, Xie X, Wang Y, Song G, et al. Degalactotigonin, a Natural Compound from Solanum nigrum L., Inhibits Growth and Metastasis of Osteosarcoma through GSK3β Inactivation-Mediated Repression of the Hedgehog/Gli1 Pathway. Clin Cancer Res. 2018;24:130-144 pubmed publisher |
- western blot; human; loading ...; fig 8a
| Wu X, Kosaraju J, Tam K. SLM, a novel carbazole-based fluorophore attenuates okadaic acid-induced tau hyperphosphorylation via down-regulating GSK-3? activity in SH-SY5Y cells. Eur J Pharm Sci. 2017;110:101-108 pubmed publisher |
- western blot; human; loading ...; fig 1b
| Sahu U, Choudhury A, Parvez S, Biswas S, Kar S. Induction of intestinal stemness and tumorigenicity by aberrant internalization of commensal non-pathogenic E. coli. Cell Death Dis. 2017;8:e2667 pubmed publisher |
- western blot; human; fig 2c
| Grabinski T, Kanaan N. Novel Non-phosphorylated Serine 9/21 GSK3?/? Antibodies: Expanding the Tools for Studying GSK3 Regulation. Front Mol Neurosci. 2016;9:123 pubmed |
- western blot; mouse; loading ...; fig 3a
| Gómez Salinero J, López Olañeta M, Ortiz Sánchez P, Larrasa Alonso J, Gatto A, Felkin L, et al. The Calcineurin Variant CnA?1 Controls Mouse Embryonic Stem Cell Differentiation by Directing mTORC2 Membrane Localization and Activation. Cell Chem Biol. 2016;23:1372-1382 pubmed publisher |
- immunohistochemistry; human; 1:200; loading ...; fig s8c
| Li C, Lim S, Xia W, Lee H, Chan L, Kuo C, et al. Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity. Nat Commun. 2016;7:12632 pubmed publisher |
- western blot; human; loading ...; fig 7a
| Cao L, Zhang L, Zhao X, Zhang Y. A Hybrid Chalcone Combining the Trimethoxyphenyl and Isatinyl Groups Targets Multiple Oncogenic Proteins and Pathways in Hepatocellular Carcinoma Cells. PLoS ONE. 2016;11:e0161025 pubmed publisher |
- western blot; mouse; 1:1000; fig 1d
| Hammers D, Sleeper M, Forbes S, Shima A, Walter G, Sweeney H. Tadalafil Treatment Delays the Onset of Cardiomyopathy in Dystrophin-Deficient Hearts. J Am Heart Assoc. 2016;5: pubmed publisher |
- western blot; human; loading ...; fig 1c
| Liu J, Wan L, Liu J, Yuan Z, Zhang J, Guo J, et al. Cdh1 inhibits WWP2-mediated ubiquitination of PTEN to suppress tumorigenesis in an APC-independent manner. Cell Discov. 2016;2:15044 pubmed publisher |
- western blot; mouse; fig s4
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- western blot; mouse; 1:500; fig s1
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- western blot; human; fig 5
| Xi Z, Yao M, Li Y, Xie C, Holst J, Liu T, et al. Guttiferone K impedes cell cycle re-entry of quiescent prostate cancer cells via stabilization of FBXW7 and subsequent c-MYC degradation. Cell Death Dis. 2016;7:e2252 pubmed publisher |
- western blot; human; fig 4
| Li B, Sun J, Dong Z, Xue P, He X, Liao L, et al. GCN5 modulates osteogenic differentiation of periodontal ligament stem cells through DKK1 acetylation in inflammatory microenvironment. Sci Rep. 2016;6:26542 pubmed publisher |
- western blot; human; fig 3
| Guinot A, Oeztuerk Winder F, Ventura J. miR-17-92/p38? Dysregulation Enhances Wnt Signaling and Selects Lgr6+ Cancer Stem-like Cells during Lung Adenocarcinoma Progression. Cancer Res. 2016;76:4012-22 pubmed publisher |
- western blot; rat; loading ...; fig 1a
| Ge N, Liu C, Li G, Xie L, Zhang Q, Li L, et al. Hydrosulfide attenuates acute myocardial ischemic injury through the glycogen synthase kinase-3?/?-catenin signaling pathway. Int J Mol Med. 2016;37:1281-9 pubmed publisher |
- western blot; human; fig 3
| Hansen N, Hjort L, Broholm C, Gillberg L, Schrölkamp M, Schultz H, et al. Metabolic and Transcriptional Changes in Cultured Muscle Stem Cells from Low Birth Weight Subjects. J Clin Endocrinol Metab. 2016;101:2254-64 pubmed publisher |
- western blot; mouse; 1:1000; fig 2
| Pan Y, Deng Y, Xie S, Wang Z, Wang Y, Ren J, et al. Altered Wnt Signaling Pathway in Cognitive Impairment Caused by Chronic Intermittent Hypoxia: Focus on Glycogen Synthase Kinase-3? and ?-catenin. Chin Med J (Engl). 2016;129:838-45 pubmed publisher |
- immunohistochemistry; human; 1:100; fig 6
- western blot; human; fig 1
| Gao X, Feng J, He Y, Xu F, Fan X, Huang W, et al. hnRNPK inhibits GSK3β Ser9 phosphorylation, thereby stabilizing c-FLIP and contributes to TRAIL resistance in H1299 lung adenocarcinoma cells. Sci Rep. 2016;6:22999 pubmed publisher |
- western blot; mouse; fig 3
| Kral J, Kuttke M, Schrottmaier W, Birnecker B, Warszawska J, Wernig C, et al. Sustained PI3K Activation exacerbates BLM-induced Lung Fibrosis via activation of pro-inflammatory and pro-fibrotic pathways. Sci Rep. 2016;6:23034 pubmed publisher |
- western blot; human; fig 2
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| Liu T, Fang Z, Wang G, Shi M, Wang X, Jiang K, et al. Anti-tumor activity of the TRPM8 inhibitor BCTC in prostate cancer DU145 cells. Oncol Lett. 2016;11:182-188 pubmed |
- western blot; mouse; fig 1
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- western blot; human; fig 4
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- western blot; mouse; 1:1000; fig 6
| Bian Y, Yang L, Wang Z, Wang Q, Zeng L, Xu G. Repeated Three-Hour Maternal Separation Induces Depression-Like Behavior and Affects the Expression of Hippocampal Plasticity-Related Proteins in C57BL/6N Mice. Neural Plast. 2015;2015:627837 pubmed publisher |
- western blot; human; 1:1000; tbl 1
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- western blot; mouse; fig 3
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- western blot; mouse; fig 2
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- western blot; human; 1:3000; fig 1c
- western blot; mouse; 1:3000; fig 1b
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- western blot; mouse; 1:1000; fig 5
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- western blot; human; 1:1000
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- western blot; human; fig 5
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- flow cytometry; human; loading ...; fig 6
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- immunocytochemistry; human; 1:300
- western blot; human
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- western blot; rat
- western blot; mouse
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- western blot; mouse; 1:500
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