product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-Tyk2 (Tyr1054/1055) Antibody
catalog :
9321
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 6a
Eletto D, Burns S, Angulo I, Plagnol V, Gilmour K, Henriquez F, et al. Biallelic JAK1 mutations in immunodeficient patient with mycobacterial infection. Nat Commun. 2016;7:13992 pubmed publisher
  • western blot; human; fig 3
Peng H, Cheng Y, Hsu Y, Wu G, Kuo C, Liou J, et al. MPT0B098, a Microtubule Inhibitor, Suppresses JAK2/STAT3 Signaling Pathway through Modulation of SOCS3 Stability in Oral Squamous Cell Carcinoma. PLoS ONE. 2016;11:e0158440 pubmed publisher
  • western blot; mouse; fig 4
Cheng F, Lienlaf M, Wang H, Perez Villarroel P, Lee C, Woan K, et al. A novel role for histone deacetylase 6 in the regulation of the tolerogenic STAT3/IL-10 pathway in APCs. J Immunol. 2014;193:2850-62 pubmed publisher
Hallenborg P, Siersbæk M, Barrio Hernandez I, Nielsen R, Kristiansen K, Mandrup S, et al. MDM2 facilitates adipocyte differentiation through CRTC-mediated activation of STAT3. Cell Death Dis. 2016;7:e2289 pubmed publisher
Canté Barrett K, Spijkers Hagelstein J, Buijs Gladdines J, Uitdehaag J, Smits W, van der Zwet J, et al. MEK and PI3K-AKT inhibitors synergistically block activated IL7 receptor signaling in T-cell acute lymphoblastic leukemia. Leukemia. 2016;30:1832-43 pubmed publisher
Fiedler J, Strauss G, Wannack M, Schwiebert S, Seidel K, Henning K, et al. Two patterns of thrombopoietin signaling suggest no coupling between platelet production and thrombopoietin reactivity in thrombocytopenia-absent radii syndrome. Haematologica. 2012;97:73-81 pubmed publisher
product information
SKU :
9321S
Product-Name :
Phospho-Tyk2 (Tyr1054/1055) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, (M, R)
Applications :
Western blot
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
140
Host :
Rabbit
Target :
Tyk2 (Tyr1054/Tyr1055) phosphate
Primary-Protein :
Tyk2
Alt-Names :
JTK1,Non-receptor tyrosine-protein kinase TYK2,TYK2,tyrosine kinase 2
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.