product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-Stat5 (Tyr694) (C71E5) Rabbit mAb
catalog :
9314
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
clone name :
C71E5
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 23
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:500; loading ...; fig 4e
Jia Y, Qi Y, Wang Y, Ma X, Xu Y, Wang J, et al. Overexpression of CD59 inhibits apoptosis of T-acute lymphoblastic leukemia via AKT/Notch1 signaling pathway. Cancer Cell Int. 2019;19:9 pubmed publisher
  • western blot; mouse; loading ...; fig s5c
Izumi T, Imai J, Yamamoto J, Kawana Y, Endo A, Sugawara H, et al. Vagus-macrophage-hepatocyte link promotes post-injury liver regeneration and whole-body survival through hepatic FoxM1 activation. Nat Commun. 2018;9:5300 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4a
Yang Y, Hu S, Liu J, Cui Y, Fan Y, Lv T, et al. CD8+ T cells promote proliferation of benign prostatic hyperplasia epithelial cells under low androgen level via modulation of CCL5/STAT5/CCND1 signaling pathway. Sci Rep. 2017;7:42893 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 5b
Willi M, Yoo K, Wang C, Trajanoski Z, Hennighausen L. Differential cytokine sensitivities of STAT5-dependent enhancers rely on Stat5 autoregulation. Nucleic Acids Res. 2016;44:10277-10291 pubmed
  • flow cytometry; mouse; loading ...; fig 2i
Chopra M, Biehl M, Steinfatt T, Brandl A, Kums J, Amich J, et al. Exogenous TNFR2 activation protects from acute GvHD via host T reg cell expansion. J Exp Med. 2016;213:1881-900 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; fig 1
Senzacqua M, Severi I, Perugini J, Acciarini S, Cinti S, Giordano A. Action of Administered Ciliary Neurotrophic Factor on the Mouse Dorsal Vagal Complex. Front Neurosci. 2016;10:289 pubmed publisher
  • flow cytometry; mouse
  • western blot; mouse; fig 5g
Cao G, Wang Q, Li G, Meng Z, Liu H, Tong J, et al. mTOR inhibition potentiates cytotoxicity of V?4 ?? T cells via up-regulating NKG2D and TNF-?. J Leukoc Biol. 2016;100:1181-1189 pubmed
  • western blot; human; tbl 1
Lombardo G, Dentelli P, Togliatto G, Rosso A, Gili M, Gallo S, et al. Activated Stat5 trafficking Via Endothelial Cell-derived Extracellular Vesicles Controls IL-3 Pro-angiogenic Paracrine Action. Sci Rep. 2016;6:25689 pubmed publisher
  • western blot; human; fig 8d
Heir P, Srikumar T, Bikopoulos G, Bunda S, Poon B, Lee J, et al. Oxygen-dependent Regulation of Erythropoietin Receptor Turnover and Signaling. J Biol Chem. 2016;291:7357-72 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 2a
Mignacca L, Saint Germain E, Benoit A, Bourdeau V, Moro A, Ferbeyre G. Sponges against miR-19 and miR-155 reactivate the p53-Socs1 axis in hematopoietic cancers. Cytokine. 2016;82:80-6 pubmed publisher
  • immunocytochemistry; mouse; fig 1
  • western blot; mouse; fig 2
  • western blot; human; fig 1
Park H, Li J, Hannah R, Biddie S, Leal Cervantes A, Kirschner K, et al. Cytokine-induced megakaryocytic differentiation is regulated by genome-wide loss of a uSTAT transcriptional program. EMBO J. 2016;35:580-94 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2a
Ma S, Yang L, Niu T, Cheng C, Zhong L, Zheng M, et al. SKLB-677, an FLT3 and Wnt/β-catenin signaling inhibitor, displays potent activity in models of FLT3-driven AML. Sci Rep. 2015;5:15646 pubmed publisher
  • immunocytochemistry; human; 1:100
Chatain N, Ziegler P, Fahrenkamp D, Jost E, Moriggl R, Schmitz Van de Leur H, et al. Src family kinases mediate cytoplasmic retention of activated STAT5 in BCR-ABL-positive cells. Oncogene. 2013;32:3587-97 pubmed publisher
Liao Y, Du W. An Rb family-independent E2F3 transcription factor variant impairs STAT5 signaling and mammary gland remodeling during pregnancy in mice. J Biol Chem. 2018;293:3156-3167 pubmed publisher
Bagci H, Laurin M, Huber J, Muller W, Côté J. Impaired cell death and mammary gland involution in the absence of Dock1 and Rac1 signaling. Cell Death Dis. 2014;5:e1375 pubmed publisher
Sharma N, Everingham S, Zeng L, Zhang Z, Kapur R, Craig A. Oncogenic KIT-induced aggressive systemic mastocytosis requires SHP2/PTPN11 phosphatase for disease progression in mice. Oncotarget. 2014;5:6130-41 pubmed
Alnaeeli M, Raaka B, Gavrilova O, Teng R, Chanturiya T, Noguchi C. Erythropoietin signaling: a novel regulator of white adipose tissue inflammation during diet-induced obesity. Diabetes. 2014;63:2415-31 pubmed publisher
Huang Z, Gao M, Li Q, Tao K, Xiao Q, Cao W, et al. Induction of apoptosis by directing oncogenic Bcr-Abl into the nucleus. Oncotarget. 2013;4:2249-60 pubmed
Theodorou M, Speletas M, Mamara A, Papachristopoulou G, Lazou V, Scorilas A, et al. Identification of a STAT5 target gene, Dpf3, provides novel insights in chronic lymphocytic leukemia. PLoS ONE. 2013;8:e76155 pubmed publisher
Jensen K, Hu K, Whitmarsh R, Hassan M, Julien L, Lu D, et al. Toxoplasma gondii rhoptry 16 kinase promotes host resistance to oral infection and intestinal inflammation only in the context of the dense granule protein GRA15. Infect Immun. 2013;81:2156-67 pubmed publisher
Nabinger S, Li X, Ramdas B, He Y, Zhang X, Zeng L, et al. The protein tyrosine phosphatase, Shp2, positively contributes to FLT3-ITD-induced hematopoietic progenitor hyperproliferation and malignant disease in vivo. Leukemia. 2013;27:398-408 pubmed publisher
Morandi F, Prigione I, Airoldi I. Human TCR??+ T cells represent a novel target for IL-27 activity. Eur J Immunol. 2012;42:1547-52 pubmed publisher
Zorzoli A, Di Carlo E, Cocco C, Ognio E, Ribatti D, Ferretti E, et al. Interleukin-27 inhibits the growth of pediatric acute myeloid leukemia in NOD/SCID/Il2rg-/- mice. Clin Cancer Res. 2012;18:1630-40 pubmed publisher
product information
SKU :
9314S
Product-Name :
Phospho-Stat5 (Tyr694) (C71E5) Rabbit mAb
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, (R, Mk, B)
Applications :
Flow cytometry
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
90
Host :
Rabbit
Target :
STAT5A (Tyr694) phosphate/STAT5B (Tyr699) phosphate
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.