product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Rb (4H1) Mouse mAb
catalog :
9309S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
mouse
clone name :
4H1
reactivity :
human, cow
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation
citations: 9
Published Application/Species/DilutionReference
  • western blot; human; fig 3
Chen Z, Wang Z, Pang J, Yu Y, Bieerkehazhi S, Lu J, et al. Multiple CDK inhibitor dinaciclib suppresses neuroblastoma growth via inhibiting CDK2 and CDK9 activity. Sci Rep. 2016;6:29090 pubmed publisher
  • western blot; human; 1:2000
McFarlane M, MacDonald A, Stevenson A, Graham S. Human Papillomavirus 16 Oncoprotein Expression Is Controlled by the Cellular Splicing Factor SRSF2 (SC35). J Virol. 2015;89:5276-87 pubmed publisher
  • western blot; human; fig 4f
Myklebust L, Van Damme P, Støve S, Dörfel M, Abboud A, Kalvik T, et al. Biochemical and cellular analysis of Ogden syndrome reveals downstream Nt-acetylation defects. Hum Mol Genet. 2015;24:1956-76 pubmed publisher
  • western blot; human; 1:1000
Gao D, Vela I, Sboner A, Iaquinta P, Karthaus W, Gopalan A, et al. Organoid cultures derived from patients with advanced prostate cancer. Cell. 2014;159:176-87 pubmed publisher
  • western blot; human; fig 2d
Chipumuro E, Marco E, Christensen C, Kwiatkowski N, Zhang T, Hatheway C, et al. CDK7 inhibition suppresses super-enhancer-linked oncogenic transcription in MYCN-driven cancer. Cell. 2014;159:1126-39 pubmed publisher
  • western blot; human
Negishi M, Wongpalee S, Sarkar S, Park J, Lee K, Shibata Y, et al. A new lncRNA, APTR, associates with and represses the CDKN1A/p21 promoter by recruiting polycomb proteins. PLoS ONE. 2014;9:e95216 pubmed publisher
  • western blot; human
Burkhardt L, Fuchs S, Krohn A, Masser S, Mader M, Kluth M, et al. CHD1 is a 5q21 tumor suppressor required for ERG rearrangement in prostate cancer. Cancer Res. 2013;73:2795-805 pubmed publisher
  • western blot; human; fig 5
Sappino A, Buser R, Seguin Q, Fernet M, Lesne L, Gumy-Pause F, et al. The CEACAM1 tumor suppressor is an ATM and p53-regulated gene required for the induction of cellular senescence by DNA damage. Oncogenesis. 2012;1:e7 pubmed publisher
Anders L, Ke N, Hydbring P, Choi Y, Widlund H, Chick J, et al. A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells. Cancer Cell. 2011;20:620-34 pubmed publisher
product information
SKU :
9309S
Product-Name :
Rb (4H1) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, Mk, B, Pg
Applications :
Chromatin Immunoprecipitation
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
110
Host :
Mouse
Target :
Rb
Primary-Protein :
Rb
Alt-Names :
OSRC,RB1,Rb,Retinoblastoma-associated protein,p105-Rb,pRb,pp110,retinoblastoma 1,retinoblastoma suspectibility protein
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.