Phospho-p53 (Ser15) Antibody | Cell Signaling Technology 9284S product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Phospho-p53 (Ser15) Antibody

catalog :

9284S

quantity :

100 ul

price :

274 USD

clonality :

polyclonal

host :

rabbit

antigen modification :

phosphorylated

reactivity :

human, mouse, rat, pig, rabbit

application :

western blot, immunocytochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, other

more info or order :

Cell Signaling Technology product webpage

citations: 92

Published Application/Species/Dilution	Reference
western blot (knockout validation); human; fig 5	Wu C, Huang K, Yang T, Li Y, Wen C, Hsu S, et al. The Topoisomerase 1 Inhibitor Austrobailignan-1 Isolated from Koelreuteria henryi Induces a G2/M-Phase Arrest and Cell Death Independently of p53 in Non-Small Cell Lung Cancer Cells. PLoS ONE. 2015;10:e0132052 pubmed publisher
western blot (knockout validation); mouse; fig 4a	Kawabata T, Yamaguchi S, Buske T, Luebben S, Wallace M, Matise I, et al. A reduction of licensed origins reveals strain-specific replication dynamics in mice. Mamm Genome. 2011;22:506-17 pubmed publisher
western blot; human; fig s5	Cristini A, Park J, Capranico G, Legube G, Favre G, Sordet O. DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions. Nucleic Acids Res. 2016;44:1161-78 pubmed publisher
western blot; human; 1:1000; fig 1	Gupta Y, Pasupuleti V, Du W, Welford S. Macrophage Migration Inhibitory Factor Secretion Is Induced by Ionizing Radiation and Oxidative Stress in Cancer Cells. PLoS ONE. 2016;11:e0146482 pubmed publisher
western blot; mouse; fig s1	Barroso-González J, Auclair S, Luan S, Thomas L, Atkins K, Aslan J, et al. PACS-2 mediates the ATM and NF-κB-dependent induction of anti-apoptotic Bcl-xL in response to DNA damage. Cell Death Differ. 2016;: pubmed publisher
western blot; mouse; fig 3	He D, Xiang J, Li B, Liu H. The dynamic behavior of Ect2 in response to DNA damage. Sci Rep. 2016;6:24504 pubmed publisher
western blot; human; 1:1000; fig 1	Ortega-Atienza S, Wong V, Deloughery Z, Luczak M, Zhitkovich A. ATM and KAT5 safeguard replicating chromatin against formaldehyde damage. Nucleic Acids Res. 2016;44:198-209 pubmed publisher
western blot; rat; fig 3	Delmas E, Jah N, Pirou C, Bouleau S, Le Floch N, Vayssiere J, et al. FGF1 C-terminal domain and phosphorylation regulate intracrine FGF1 signaling for its neurotrophic and anti-apoptotic activities. Cell Death Dis. 2016;7:e2079 pubmed publisher
western blot; human; 1:1000; fig 5	Lee W, Jo S, Lee M, Won C, Lee M, Choi J, et al. The Effect of MCP-1/CCR2 on the Proliferation and Senescence of Epidermal Constituent Cells in Solar Lentigo. Int J Mol Sci. 2016;17: pubmed publisher
western blot; human; fig 1	Hall A, Lu W, Godfrey J, Antonov A, Paicu C, Moxon S, et al. The cytoskeleton adaptor protein ankyrin-1 is upregulated by p53 following DNA damage and alters cell migration. Cell Death Dis. 2016;7:e2184 pubmed publisher
western blot; human; fig 1	Pecháčková S, Burdova K, Benada J, Kleiblova P, Jenikova G, Macurek L. Inhibition of WIP1 phosphatase sensitizes breast cancer cells to genotoxic stress and to MDM2 antagonist nutlin-3. Oncotarget. 2016;7:14458-75 pubmed publisher
western blot; human; fig 2	Kazantseva J, Sadam H, Neuman T, Palm K. Targeted alternative splicing of TAF4: a new strategy for cell reprogramming. Sci Rep. 2016;6:30852 pubmed publisher
western blot; human; fig 1	Pandiri I, Chen Y, Joe Y, Kim H, Park J, Chung H, et al. Tristetraprolin mediates the anti-proliferative effects of metformin in breast cancer cells. Breast Cancer Res Treat. 2016;156:57-64 pubmed publisher
western blot; human	Mortusewicz O, Evers B, Helleday T. PC4 promotes genome stability and DNA repair through binding of ssDNA at DNA damage sites. Oncogene. 2016;35:761-70 pubmed publisher
western blot; human; fig 3a	Petroni M, Sardina F, Heil C, Sahún-Roncero M, Colicchia V, Veschi V, et al. The MRN complex is transcriptionally regulated by MYCN during neural cell proliferation to control replication stress. Cell Death Differ. 2016;23:197-206 pubmed publisher
western blot; human; fig 5j	Capell B, Drake A, Zhu J, Shah P, Dou Z, Dorsey J, et al. MLL1 is essential for the senescence-associated secretory phenotype. Genes Dev. 2016;30:321-36 pubmed publisher
western blot; mouse; 1:1000; fig 6	Koppaka V, Chen Y, Mehta G, Orlicky D, Thompson D, Jester J, et al. ALDH3A1 Plays a Functional Role in Maintenance of Corneal Epithelial Homeostasis. PLoS ONE. 2016;11:e0146433 pubmed publisher
western blot; human; fig 1	Meena J, Cerutti A, Beichler C, Morita Y, Bruhn C, Kumar M, et al. Telomerase abrogates aneuploidy-induced telomere replication stress, senescence and cell depletion. EMBO J. 2015;34:1371-84 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:200; tbl he following antibodies were used for IHC analysis: MCM3 (generated in rabbits immunized with synthetic peptide N-CSQEDTEQKRKRRK-C conjugated to KLH; Sigma-Genosys, UK; serum was used at 1:500 dilution), Ki67 (Master Diagnostica, 0003110QD; 1:500), ??H2AX (Millipore, 05-636; 1:100), pS15-p53 (Cell Signaling, 9284; 1:200), Ter119 (BD, 550565; 1:50), Pax5 (Santa Cruz Biotechnology, sc-1974; 1:50), CD3 (Santa Cruz Biotechnology, sc-1127; 1:50) and FVIII (Dako, A0082; 1:200).	Alvarez S, Diaz M, Flach J, Rodríguez-Acebes S, López-Contreras A, Martinez D, et al. Replication stress caused by low MCM expression limits fetal erythropoiesis and hematopoietic stem cell functionality. Nat Commun. 2015;6:8548 pubmed publisher
western blot; mouse	Xu H, Zhou Y, Coughlan K, Ding Y, Wang S, Wu Y, et al. AMPKα1 deficiency promotes cellular proliferation and DNA damage via p21 reduction in mouse embryonic fibroblasts. Biochim Biophys Acta. 2015;1853:65-73 pubmed publisher
western blot; human; 1:1000; fig 2	Sedic M, Skibinski A, Brown N, Gallardo M, Mulligan P, Martinez P, et al. Haploinsufficiency for BRCA1 leads to cell-type-specific genomic instability and premature senescence. Nat Commun. 2015;6:7505 pubmed publisher
western blot; human western blot; mouse	Vassilopoulos A, Tominaga Y, Kim H, Lahusen T, Li B, Yu H, et al. WEE1 murine deficiency induces hyper-activation of APC/C and results in genomic instability and carcinogenesis. Oncogene. 2015;34:3023-35 pubmed publisher
immunohistochemistry - paraffin section; mouse; fig 6b	Lebrun-Julien F, Suter U. Combined HDAC1 and HDAC2 Depletion Promotes Retinal Ganglion Cell Survival After Injury Through Reduction of p53 Target Gene Expression. ASN Neuro. 2015;7: pubmed publisher
western blot; human; 1:1000	Wei Z, Guo H, Liu Z, Zhang X, Liu Q, Qian Y, et al. CUL4B impedes stress-induced cellular senescence by dampening a p53-reactive oxygen species positive feedback loop. Free Radic Biol Med. 2015;79:1-13 pubmed publisher
western blot; human; 1:1000	Ambrosio S, Amente S, Napolitano G, Di Palo G, Lania L, Majello B. MYC impairs resolution of site-specific DNA double-strand breaks repair. Mutat Res. 2015;774:6-13 pubmed publisher
western blot; human	Kiyonari S, Iimori M, Matsuoka K, Watanabe S, Morikawa-Ichinose T, Miura D, et al. The 1,2-Diaminocyclohexane Carrier Ligand in Oxaliplatin Induces p53-Dependent Transcriptional Repression of Factors Involved in Thymidylate Biosynthesis. Mol Cancer Ther. 2015;14:2332-42 pubmed publisher
western blot; human; fig 6d	Hilton B, Li Z, Musich P, Wang H, Cartwright B, SERRANO M, et al. ATR Plays a Direct Antiapoptotic Role at Mitochondria, which Is Regulated by Prolyl Isomerase Pin1. Mol Cell. 2015;60:35-46 pubmed publisher
western blot; rabbit; 1:1000; fig 3	Varela A, Piperi C, Sigala F, Agrogiannis G, Davos C, Andri M, et al. Elevated expression of mechanosensory polycystins in human carotid atherosclerotic plaques: association with p53 activation and disease severity. Sci Rep. 2015;5:13461 pubmed publisher
western blot; human; 1:1000	Ortega-Atienza S, Green S, Zhitkovich A. Proteasome activity is important for replication recovery, CHK1 phosphorylation and prevention of G2 arrest after low-dose formaldehyde. Toxicol Appl Pharmacol. 2015;286:135-41 pubmed publisher
western blot; human; 1:1000; fig 4	Ohashi A, Ohori M, Iwai K, Nakayama Y, Nambu T, Morishita D, et al. Aneuploidy generates proteotoxic stress and DNA damage concurrently with p53-mediated post-mitotic apoptosis in SAC-impaired cells. Nat Commun. 2015;6:7668 pubmed publisher
western blot; human; 1:500; fig 2.e	Laberge R, Sun Y, Orjalo A, Patil C, Freund A, Zhou L, et al. MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation. Nat Cell Biol. 2015;17:1049-61 pubmed publisher
other; mouse; 1:1000; fig s1	Chiang C, Uzoma I, Lane D, Memisevic V, Alem F, Yao K, et al. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Front Microbiol. 2015;6:683 pubmed publisher
western blot; human; 1:1000; fig 3	Cañeque T, Gomes F, Mai T, Maestri G, Malacria M, Rodriguez R. Synthesis of marmycin A and investigation into its cellular activity. Nat Chem. 2015;7:744-51 pubmed publisher
western blot; human; fig 3	Wang W, Catto J, Meuth M. Differential response of normal and malignant urothelial cells to CHK1 and ATM inhibitors. Oncogene. 2015;34:2887-96 pubmed publisher
western blot; pig; fig 2	Simões M, Martins C, Ferreira F. Early intranuclear replication of African swine fever virus genome modifies the landscape of the host cell nucleus. Virus Res. 2015;210:1-7 pubmed publisher
western blot; mouse; 1:1000; fig 3	Zhao J, Li H, Zhou R, Ma G, Dekker J, Tucker H, et al. Foxp1 Regulates the Proliferation of Hair Follicle Stem Cells in Response to Oxidative Stress during Hair Cycling. PLoS ONE. 2015;10:e0131674 pubmed publisher
western blot; human; 1:500	Tréhoux S, Lahdaoui F, Delpu Y, Renaud F, Leteurtre E, Torrisani J, et al. Micro-RNAs miR-29a and miR-330-5p function as tumor suppressors by targeting the MUC1 mucin in pancreatic cancer cells. Biochim Biophys Acta. 2015;1853:2392-403 pubmed publisher
western blot; mouse; 1:10000; fig 2b	Lindsey-Boltz L, Kemp M, Reardon J, DEROCCO V, Iyer R, Modrich P, et al. Coupling of human DNA excision repair and the DNA damage checkpoint in a defined in vitro system. J Biol Chem. 2014;289:5074-82 pubmed publisher
western blot; mouse; fig 2d	Adeyemi R, Pintel D. Parvovirus-induced depletion of cyclin B1 prevents mitotic entry of infected cells. PLoS Pathog. 2014;10:e1003891 pubmed publisher
western blot; human; 1:1000	Penicud K, Behrens A. DMAP1 is an essential regulator of ATM activity and function. Oncogene. 2014;33:525-31 pubmed publisher
western blot; human	Kemp M, Gaddameedhi S, Choi J, Hu J, Sancar A. DNA repair synthesis and ligation affect the processing of excised oligonucleotides generated by human nucleotide excision repair. J Biol Chem. 2014;289:26574-83 pubmed publisher
western blot; rat; 1:1000	Ureshino R, Hsu Y, do Carmo L, Yokomizo C, Nantes I, Smaili S. Inhibition of cytoplasmic p53 differentially modulates Ca(2+) signaling and cellular viability in young and aged striata. Exp Gerontol. 2014;58:120-7 pubmed publisher
western blot; mouse	Guo M, Cao Y, Wang T, Song X, Liu Z, Zhou E, et al. Baicalin inhibits Staphylococcus aureus-induced apoptosis by regulating TLR2 and TLR2-related apoptotic factors in the mouse mammary glands. Eur J Pharmacol. 2014;723:481-8 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:200	Maserati M, Dai X, Walentuk M, Mager J. Identification of four genes required for mammalian blastocyst formation. Zygote. 2014;22:331-9 pubmed publisher
western blot; human western blot; mouse western blot; rat	Sabirzhanov B, Zhao Z, Stoica B, Loane D, Wu J, Borroto C, et al. Downregulation of miR-23a and miR-27a following experimental traumatic brain injury induces neuronal cell death through activation of proapoptotic Bcl-2 proteins. J Neurosci. 2014;34:10055-71 pubmed publisher
western blot; mouse	Schweikl H, Petzel C, Bolay C, Hiller K, Buchalla W, Krifka S. 2-Hydroxyethyl methacrylate-induced apoptosis through the ATM- and p53-dependent intrinsic mitochondrial pathway. Biomaterials. 2014;35:2890-904 pubmed publisher
western blot; mouse; fig 5	Lin H, Lin S, Chung Y, Vonderfecht S, Camden J, Flodby P, et al. Dynamic involvement of ATG5 in cellular stress responses. Cell Death Dis. 2014;5:e1478 pubmed publisher
western blot; mouse	Meijer D, Sun Y, Liu T, Kane M, Alberta J, Adelmant G, et al. An amino terminal phosphorylation motif regulates intranuclear compartmentalization of Olig2 in neural progenitor cells. J Neurosci. 2014;34:8507-18 pubmed publisher
western blot; human	Giovannini C, Minguzzi M, Baglioni M, Fornari F, Giannone F, Ravaioli M, et al. Suppression of p53 by Notch3 is mediated by Cyclin G1 and sustained by MDM2 and miR-221 axis in hepatocellular carcinoma. Oncotarget. 2014;5:10607-20 pubmed
western blot; human	Tomicic M, Aasland D, Naumann S, Meise R, Barckhausen C, Kaina B, et al. Translesion polymerase η is upregulated by cancer therapeutics and confers anticancer drug resistance. Cancer Res. 2014;74:5585-96 pubmed publisher
western blot; human	Lu H, Fang E, Sykora P, Kulikowicz T, Zhang Y, Becker K, et al. Senescence induced by RECQL4 dysfunction contributes to Rothmund-Thomson syndrome features in mice. Cell Death Dis. 2014;5:e1226 pubmed publisher
western blot; human; fig 1	Klaus C, Kaemmerer E, Reinartz A, Schneider U, Plum P, Jeon M, et al. TP53 status regulates ACSL5-induced expression of mitochondrial mortalin in enterocytes and colorectal adenocarcinomas. Cell Tissue Res. 2014;357:267-78 pubmed publisher
western blot; human	Ji X, Lu H, Zhou Q, Luo K. LARP7 suppresses P-TEFb activity to inhibit breast cancer progression and metastasis. elife. 2014;3:e02907 pubmed publisher
western blot; human; fig 1	Iannetti A, Ledoux A, Tudhope S, Sellier H, Zhao B, Mowla S, et al. Regulation of p53 and Rb links the alternative NF-κB pathway to EZH2 expression and cell senescence. PLoS Genet. 2014;10:e1004642 pubmed publisher
western blot; human	Lin B, Gupta D, Heinen C. Human pluripotent stem cells have a novel mismatch repair-dependent damage response. J Biol Chem. 2014;289:24314-24 pubmed publisher
immunohistochemistry - paraffin section; human western blot; human	Wang C, Wang J, Liu Z, Ma X, Wang X, Jin H, et al. Ubiquitin-specific protease 2a stabilizes MDM4 and facilitates the p53-mediated intrinsic apoptotic pathway in glioblastoma. Carcinogenesis. 2014;35:1500-9 pubmed publisher
western blot; rat; 1:1000	Jebelli J, Hooper C, Pocock J. Microglial p53 activation is detrimental to neuronal synapses during activation-induced inflammation: Implications for neurodegeneration. Neurosci Lett. 2014;583:92-7 pubmed publisher
western blot; rat; 1:1000	Borkham-Kamphorst E, Schaffrath C, Van De Leur E, Haas U, Tihaa L, Meurer S, et al. The anti-fibrotic effects of CCN1/CYR61 in primary portal myofibroblasts are mediated through induction of reactive oxygen species resulting in cellular senescence, apoptosis and attenuated TGF-β signaling. Biochim Biophys Acta. 2014;1843:902-14 pubmed publisher
western blot; human	Kazantseva J, Kivil A, Tints K, Kazantseva A, Neuman T, Palm K. Alternative splicing targeting the hTAF4-TAFH domain of TAF4 represses proliferation and accelerates chondrogenic differentiation of human mesenchymal stem cells. PLoS ONE. 2013;8:e74799 pubmed publisher
western blot; mouse; 1:800	Licandro G, Ling Khor H, Beretta O, Lai J, Derks H, Laudisi F, et al. The NLRP3 inflammasome affects DNA damage responses after oxidative and genotoxic stress in dendritic cells. Eur J Immunol. 2013;43:2126-37 pubmed publisher
immunocytochemistry; mouse western blot; human western blot; mouse	Brochier C, Dennis G, Rivieccio M, McLaughlin K, Coppola G, Ratan R, et al. Specific acetylation of p53 by HDAC inhibition prevents DNA damage-induced apoptosis in neurons. J Neurosci. 2013;33:8621-32 pubmed publisher
western blot; mouse; 1:1000	Rass E, Chandramouly G, Zha S, Alt F, Xie A. Ataxia telangiectasia mutated (ATM) is dispensable for endonuclease I-SceI-induced homologous recombination in mouse embryonic stem cells. J Biol Chem. 2013;288:7086-95 pubmed publisher
western blot; human; 1:500	Kyathanahalli C, Marks J, Nye K, Lao B, Albrecht E, Aberdeen G, et al. Cross-species withdrawal of MCL1 facilitates postpartum uterine involution in both the mouse and baboon. Endocrinology. 2013;154:4873-84 pubmed publisher
western blot; mouse	Schwab K, Smith G, Dressler G. Arrested spermatogenesis and evidence for DNA damage in PTIP mutant testes. Dev Biol. 2013;373:64-71 pubmed publisher
immunohistochemistry - frozen section; mouse western blot; human western blot; mouse	Xiong Y, Yu Y, Montani J, Yang Z, Ming X. Arginase-II induces vascular smooth muscle cell senescence and apoptosis through p66Shc and p53 independently of its l-arginine ureahydrolase activity: implications for atherosclerotic plaque vulnerability. J Am Heart Assoc. 2013;2:e000096 pubmed publisher
western blot; human	Gubanova E, Issaeva N, Gokturk C, Djureinovic T, Helleday T. SMG-1 suppresses CDK2 and tumor growth by regulating both the p53 and Cdc25A signaling pathways. Cell Cycle. 2013;12:3770-80 pubmed publisher
western blot; mouse; 1:1000	Pusapati R, Rounbehler R, Hong S, Powers J, Yan M, Kiguchi K, et al. ATM promotes apoptosis and suppresses tumorigenesis in response to Myc. Proc Natl Acad Sci U S A. 2006;103:1446-51 pubmed
immunocytochemistry; human western blot; human	Crabbe L, Cesare A, Kasuboski J, Fitzpatrick J, Karlseder J. Human telomeres are tethered to the nuclear envelope during postmitotic nuclear assembly. Cell Rep. 2012;2:1521-9 pubmed publisher
western blot; human	Liu C, Chen C, Huang A, Li J. Subamolide A, a component isolated from Cinnamomum subavenium, induces apoptosis mediated by mitochondria-dependent, p53 and ERK1/2 pathways in human urothelial carcinoma cell line NTUB1. J Ethnopharmacol. 2011;137:503-11 pubmed publisher
western blot; mouse; 1:1000	Zhang T, Penicud K, Bruhn C, Loizou J, Kanu N, Wang Z, et al. Competition between NBS1 and ATMIN controls ATM signaling pathway choice. Cell Rep. 2012;2:1498-504 pubmed publisher
western blot; human; 1:2000	Valdez B, Nieto Y, Murray D, Li Y, Wang G, Champlin R, et al. Epigenetic modifiers enhance the synergistic cytotoxicity of combined nucleoside analog-DNA alkylating agents in lymphoma cell lines. Exp Hematol. 2012;40:800-10 pubmed publisher
western blot; human; 1:1000	Benatti P, Dolfini D, Vigano A, Ravo M, Weisz A, Imbriano C. Specific inhibition of NF-Y subunits triggers different cell proliferation defects. Nucleic Acids Res. 2011;39:5356-68 pubmed publisher
western blot; human	Chen J, Ozanne S. Deep senescent human fibroblasts show diminished DNA damage foci but retain checkpoint capacity to oxidative stress. FEBS Lett. 2006;580:6669-73 pubmed
western blot; mouse	Walls K, Ghosh A, Franklin A, Klocke B, Ballestas M, Shacka J, et al. Lysosome dysfunction triggers Atg7-dependent neural apoptosis. J Biol Chem. 2010;285:10497-507 pubmed publisher
western blot; human	Dolezalova D, Mraz M, Bárta T, Plevova K, Vinarsky V, Holubcová Z, et al. MicroRNAs regulate p21(Waf1/Cip1) protein expression and the DNA damage response in human embryonic stem cells. Stem Cells. 2012;30:1362-72 pubmed publisher
western blot; human	Lau R, Niu M, Pratt M. cIAP2 represses IKKα/β-mediated activation of MDM2 to prevent p53 degradation. Cell Cycle. 2012;11:4009-19 pubmed publisher
western blot; mouse; 1:200	Zhang S, Liu X, BAWA-KHALFE T, Lu L, Lyu Y, Liu L, et al. Identification of the molecular basis of doxorubicin-induced cardiotoxicity. Nat Med. 2012;18:1639-42 pubmed publisher
	Desmarais J, Unger C, Damjanov I, Meuth M, Andrews P. Apoptosis and failure of checkpoint kinase 1 activation in human induced pluripotent stem cells under replication stress. Stem Cell Res Ther. 2016;7:17 pubmed publisher
	Kang J, Lee J, Hong D, Lee S, Kim N, Lee W, et al. Renal cell carcinoma escapes death by p53 depletion through transglutaminase 2-chaperoned autophagy. Cell Death Dis. 2016;7:e2163 pubmed publisher
	Younger S, Kenzelmann-Broz D, Jung H, Attardi L, Rinn J. Integrative genomic analysis reveals widespread enhancer regulation by p53 in response to DNA damage. Nucleic Acids Res. 2015;43:4447-62 pubmed publisher
	Lee C, Castle K, Moding E, Blum J, Williams N, Luo L, et al. Acute DNA damage activates the tumour suppressor p53 to promote radiation-induced lymphoma. Nat Commun. 2015;6:8477 pubmed publisher
	Guo W, Yan L, Yang L, Liu X, E Q, Gao P, et al. Targeting GRP75 improves HSP90 inhibitor efficacy by enhancing p53-mediated apoptosis in hepatocellular carcinoma. PLoS ONE. 2014;9:e85766 pubmed publisher
	Bussy C, Paineau E, Cambedouzou J, Brun N, Mory C, Fayard B, et al. Intracellular fate of carbon nanotubes inside murine macrophages: pH-dependent detachment of iron catalyst nanoparticles. Part Fibre Toxicol. 2013;10:24 pubmed publisher
	Pruitt S, Freeland A, Rusiniak M, Kunnev D, Cady G. Cdkn1b overexpression in adult mice alters the balance between genome and tissue ageing. Nat Commun. 2013;4:2626 pubmed publisher
	Watanabe K, Shibuya S, Koyama H, Ozawa Y, Toda T, Yokote K, et al. Sod1 loss induces intrinsic superoxide accumulation leading to p53-mediated growth arrest and apoptosis. Int J Mol Sci. 2013;14:10998-1010 pubmed publisher
	Lucas D, Scheiermann C, Chow A, Kunisaki Y, Bruns I, Barrick C, et al. Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration. Nat Med. 2013;19:695-703 pubmed publisher
	Efeyan A, Murga M, Martinez-Pastor B, Ortega-Molina A, Soria R, Collado M, et al. Limited role of murine ATM in oncogene-induced senescence and p53-dependent tumor suppression. PLoS ONE. 2009;4:e5475 pubmed publisher
	Li B, Reddy S, Comai L. Depletion of Ku70/80 reduces the levels of extrachromosomal telomeric circles and inhibits proliferation of ALT cells. Aging (Albany NY). 2011;3:395-406 pubmed
	Raab M, Kappel S, Kramer A, Sanhaji M, Matthess Y, Kurunci-Csacsko E, et al. Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells. Nat Commun. 2011;2:395 pubmed publisher
	Bosco E, Knudsen E. Differential role of RB in response to UV and IR damage. Nucleic Acids Res. 2005;33:1581-92 pubmed
	Kunnev D, Rusiniak M, Kudla A, Freeland A, Cady G, Pruitt S. DNA damage response and tumorigenesis in Mcm2-deficient mice. Oncogene. 2010;29:3630-8 pubmed publisher
	Lim S, Hung A, Porter A. Focused PCR screen reveals p53 dependence of nitric oxide-induced apoptosis and up-regulation of maspin and plasminogen activator inhibitor-1 in tumor cells. Mol Cancer Res. 2009;7:55-66 pubmed publisher

product information

SKU :

9284S

Product-Name :

Phospho-p53 (Ser15) Antibody

Size :

100 ul

Price-(USD) :

274 USD

Species-x-Reactivity :

H, M, R, Mk

Applications :

Chromatin Immunoprecipitation

Product-Category :

Cell Cycle / Checkpoint Control

Shipping-Temp :

COLD

Storage-Temp :

-20°C

Product-Type :

Polyclonal Antibody

MW :

Host :

Rabbit

Target :

p53 (Ser15) phosphate

Primary-Protein :

p53

Alt-Names :

Antigen NY-CO-13,Cellular tumor antigen p53,FLJ92943,LFS1,P53,Phosphoprotein p53,TP53,TRP53,Tumor suppressor p53,p53 antigen,p53 transformation suppressor,p53 tumor suppressor,transformation-related protein 53,tumor protein p53

more info or order :

Cell Signaling Technology product webpage