product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
SAPK/JNK (56G8) Rabbit mAb
catalog :
9258S
quantity :
200 ul
price :
235 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse, rat, cow, pig
application :
western blot
citations: 37
Published Application/Species/DilutionReference
  • western blot; rat; 1:1000; fig 3
Liu L, Lv G, Ning C, Yang Y, Zhu J. Therapeutic effects of 1,25-dihydroxyvitamin D3 on diabetes-induced liver complications in a rat model. Exp Ther Med. 2016;11:2284-2292 pubmed
  • western blot; rat; fig S3
Simard E, Söllradl T, Maltais J, Boucher J, D'Orléans-Juste P, Grandbois M. Receptor for Advanced Glycation End-Products Signaling Interferes with the Vascular Smooth Muscle Cell Contractile Phenotype and Function. PLoS ONE. 2015;10:e0128881 pubmed publisher
  • western blot; human
Yoo J, Kim T, Kong S, Lee J, Choi W, Kim K, et al. Role of Mig-6 in hepatic glucose metabolism. J Diabetes. 2015;: pubmed publisher
  • western blot; human
Lee J, Chung L, Chen Y, Feng T, Chen W, Juang H. Upregulation of B-cell translocation gene 2 by epigallocatechin-3-gallate via p38 and ERK signaling blocks cell proliferation in human oral squamous cell carcinoma cells. Cancer Lett. 2015;360:310-8 pubmed publisher
  • western blot; mouse; fig 2
Wang Y, Zhang Y, Hu W, Xie S, Gong C, Iqbal K, et al. Rapid alteration of protein phosphorylation during postmortem: implication in the study of protein phosphorylation. Sci Rep. 2015;5:15709 pubmed publisher
  • western blot; cow; 1:1000; fig 4b
Ma M, Baumgartner M. Intracellular Theileria annulata promote invasive cell motility through kinase regulation of the host actin cytoskeleton. PLoS Pathog. 2014;10:e1004003 pubmed publisher
  • western blot; human
Lee J, Park J, Kwon O, Kim H, Fornace A, Cha H. Off-target response of a Wip1 chemical inhibitor in skin keratinocytes. J Dermatol Sci. 2014;73:125-34 pubmed publisher
  • western blot; human
Jamal S, Cheriyan V, Muthu M, Munie S, Levi E, Ashour A, et al. CARP-1 functional mimetics are a novel class of small molecule inhibitors of malignant pleural mesothelioma cells. PLoS ONE. 2014;9:e89146 pubmed publisher
  • western blot; pig; 1:500
Zhang S, Ren M, Zeng X, He P, Ma X, Qiao S. Leucine stimulates ASCT2 amino acid transporter expression in porcine jejunal epithelial cell line (IPEC-J2) through PI3K/Akt/mTOR and ERK signaling pathways. Amino Acids. 2014;46:2633-42 pubmed publisher
  • western blot; mouse; 1:1000
Yu B, Chang J, Liu Y, Li J, Kevork K, Al-Hezaimi K, et al. Wnt4 signaling prevents skeletal aging and inflammation by inhibiting nuclear factor-κB. Nat Med. 2014;20:1009-17 pubmed publisher
  • western blot; human
Singel S, Batten K, Cornelius C, Jia G, Fasciani G, Barron S, et al. Receptor-interacting protein kinase 2 promotes triple-negative breast cancer cell migration and invasion via activation of nuclear factor-kappaB and c-Jun N-terminal kinase pathways. Breast Cancer Res. 2014;16:R28 pubmed publisher
  • western blot; mouse; 1:1000
Zhang Y, Zhang X, Gao L, Liu Y, Jiang D, Chen K, et al. Growth/differentiation factor 1 alleviates pressure overload-induced cardiac hypertrophy and dysfunction. Biochim Biophys Acta. 2014;1842:232-44 pubmed publisher
  • western blot; mouse
Huang S, Lee C, Wang H, Chang Y, Lin C, Chen C, et al. 6-Dehydrogingerdione restrains lipopolysaccharide-induced inflammatory responses in RAW 264.7 macrophages. J Agric Food Chem. 2014;62:9171-9 pubmed publisher
  • western blot; human
Lemire B, Debigare R, Dubé A, Thériault M, Cote C, Maltais F. MAPK signaling in the quadriceps of patients with chronic obstructive pulmonary disease. J Appl Physiol (1985). 2012;113:159-66 pubmed publisher
Garcia D, de Castro-Faria-Neto H, da Silva C, de Souza e Souza K, Gonçalves-de-Albuquerque C, Silva A, et al. Na/K-ATPase as a target for anticancer drugs: studies with perillyl alcohol. Mol Cancer. 2015;14:105 pubmed publisher
Li C, Lun W, Zhao X, Lei S, Guo Y, Ma J, et al. Allicin alleviates inflammation of trinitrobenzenesulfonic acid-induced rats and suppresses P38 and JNK pathways in Caco-2 cells. Mediators Inflamm. 2015;2015:434692 pubmed publisher
Yu G, Lee Y, Cheng C, Wu C, Song J, Gallick G, et al. RSK promotes prostate cancer progression in bone through ING3, CKAP2, and PTK6-mediated cell survival. Mol Cancer Res. 2015;13:348-57 pubmed publisher
Ting C, Huang H, Huang T, Wu C, Chen J. The mechanisms by which pardaxin, a natural cationic antimicrobial peptide, targets the endoplasmic reticulum and induces c-FOS. Biomaterials. 2014;35:3627-40 pubmed publisher
Liu J, Lin X, Yang X, Zhou L, He S, Zhuang S, et al. A novel AP-1/miR-101 regulatory feedback loop and its implication in the migration and invasion of hepatoma cells. Nucleic Acids Res. 2014;42:12041-51 pubmed publisher
Zhang J, Clark K, Lawrence T, Peggie M, Cohen P. An unexpected twist to the activation of IKKβ: TAK1 primes IKKβ for activation by autophosphorylation. Biochem J. 2014;461:531-7 pubmed publisher
Zhou H, Guo W, Zhao Y, Wang Y, Zha R, Ding J, et al. MicroRNA-135a acts as a putative tumor suppressor by directly targeting very low density lipoprotein receptor in human gallbladder cancer. Cancer Sci. 2014;105:956-65 pubmed publisher
Denoyelle C, Lambert B, Meryet-Figuiere M, Vigneron N, Brotin E, Lecerf C, et al. miR-491-5p-induced apoptosis in ovarian carcinoma depends on the direct inhibition of both BCL-XL and EGFR leading to BIM activation. Cell Death Dis. 2014;5:e1445 pubmed publisher
Li T, Song T, Ni L, Yang G, Song X, Wu L, et al. The p-ERK-p-c-Jun-cyclinD1 pathway is involved in proliferation of smooth muscle cells after exposure to cigarette smoke extract. Biochem Biophys Res Commun. 2014;453:316-20 pubmed publisher
Zeng L, Yao Y, Wang D, Chen X. Effect of microcavitary alginate hydrogel with different pore sizes on chondrocyte culture for cartilage tissue engineering. Mater Sci Eng C Mater Biol Appl. 2014;34:168-75 pubmed publisher
Trucco L, Andreoli V, Núñez N, Maccioni M, Bocco J. Krüppel-like factor 6 interferes with cellular transformation induced by the H-ras oncogene. FASEB J. 2014;28:5262-76 pubmed publisher
Sun P, Zhou K, Wang S, Li P, Chen S, Lin G, et al. Involvement of MAPK/NF-κB signaling in the activation of the cholinergic anti-inflammatory pathway in experimental colitis by chronic vagus nerve stimulation. PLoS ONE. 2013;8:e69424 pubmed publisher
Orejana L, Barros-Miñones L, Aguirre N, Puerta E. Implication of JNK pathway on tau pathology and cognitive decline in a senescence-accelerated mouse model. Exp Gerontol. 2013;48:565-71 pubmed publisher
Skrypek N, Duchene B, Hebbar M, Leteurtre E, Van Seuningen I, Jonckheere N. The MUC4 mucin mediates gemcitabine resistance of human pancreatic cancer cells via the Concentrative Nucleoside Transporter family. Oncogene. 2013;32:1714-23 pubmed publisher
Cao Y, Xia D, Qi S, Du J, Ma P, Wang S, et al. Epiregulin can promote proliferation of stem cells from the dental apical papilla via MEK/Erk and JNK signalling pathways. Cell Prolif. 2013;46:447-56 pubmed publisher
Barros-Miñones L, Orejana L, Goni-Allo B, Suquía V, Hervias I, Aguirre N, et al. Modulation of the ASK1-MKK3/6-p38/MAPK signalling pathway mediates sildenafil protection against chemical hypoxia caused by malonate. Br J Pharmacol. 2013;168:1820-34 pubmed publisher
Kosla J, Dvorakova M, Dvorak M, Cermák V. Effective myofibroblast dedifferentiation by concomitant inhibition of TGF-β signaling and perturbation of MAPK signaling. Eur J Cell Biol. 2013;92:363-73 pubmed publisher
Su J, Yen J, Li S, Weng C, Lin M, Ho C, et al. 3',4'-didemethylnobiletin induces phase II detoxification gene expression and modulates PI3K/Akt signaling in PC12 cells. Free Radic Biol Med. 2012;52:126-41 pubmed publisher
Mufson E, He B, Nadeem M, Perez S, Counts S, Leurgans S, et al. Hippocampal proNGF signaling pathways and β-amyloid levels in mild cognitive impairment and Alzheimer disease. J Neuropathol Exp Neurol. 2012;71:1018-29 pubmed publisher
Wang L, Kou M, Weng C, Hu L, Wang Y, Wu M. Arsenic modulates heme oxygenase-1, interleukin-6, and vascular endothelial growth factor expression in endothelial cells: roles of ROS, NF-κB, and MAPK pathways. Arch Toxicol. 2012;86:879-96 pubmed publisher
Sun L, Zhao R, Zhang L, Zhang T, Xin W, Lan X, et al. Salvianolic acid A inhibits PDGF-BB induced vascular smooth muscle cell migration and proliferation while does not constrain endothelial cell proliferation and nitric oxide biosynthesis. Molecules. 2012;17:3333-47 pubmed publisher
Schindler M, Fabre C, de Weille J, Carreau S, Mersel M, Bakalara N. Disruption of nongenomic testosterone signaling in a model of spinal and bulbar muscular atrophy. Mol Endocrinol. 2012;26:1102-16 pubmed publisher
Li J, Deng J, Sheng W, Zuo Z. Metformin attenuates Alzheimer's disease-like neuropathology in obese, leptin-resistant mice. Pharmacol Biochem Behav. 2012;101:564-74 pubmed publisher
product information
SKU :
9258S
Product-Name :
SAPK/JNK (56G8) Rabbit mAb
Size :
200 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Hm, Mk, Mi
Applications :
Western blot
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
46, 54
Host :
Rabbit
Target :
SAPK/JNK1
Primary-Protein :
JNK1
Alt-Names :
JNK,JNK-46,JNK1,JNK1 alpha protein kinase,JNK1 beta protein kinase,JNK1A2,JNK21B1/2,JUN N-terminal kinase,MAP kinase 8,MAPK 8,MAPK8,MK08,Mitogen-activated protein kinase 8,PRKM8,SAPK1,Stress-activated protein kinase 1,Stress-activated protein kinase JNK1,c-Jun N-terminal kinase 1,mitogen-activated protein kinase 8 isoform JNK1 alpha1,mitogen-activated protein kinase 8 isoform JNK1 beta2,protein kinase JNK1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.