product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-SAPK/JNK (Thr183/Tyr185) (G9) Mouse mAb
catalog :
9255S
quantity :
200 ul
price :
274 USD
clonality :
monoclonal
host :
mouse
antigen modification :
phosphorylated
clone name :
G9
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - free floating section
citations: 32
Published Application/Species/DilutionReference
  • western blot; mouse; 1:1000; fig 6
Wang K, Cao P, Wang H, Tang Z, Wang N, Wang J, et al. Chronic administration of Angelica sinensis polysaccharide effectively improves fatty liver and glucose homeostasis in high-fat diet-fed mice. Sci Rep. 2016;6:26229 pubmed publisher
  • western blot; human; fig s5
Ang Z, Er J, Tan N, Lu J, Liou Y, Grosse J, et al. Human and mouse monocytes display distinct signalling and cytokine profiles upon stimulation with FFAR2/FFAR3 short-chain fatty acid receptor agonists. Sci Rep. 2016;6:34145 pubmed publisher
  • western blot; mouse; fig 4C
Ni Y, Nagashimada M, Zhuge F, Zhan L, Nagata N, Tsutsui A, et al. Astaxanthin prevents and reverses diet-induced insulin resistance and steatohepatitis in mice: A comparison with vitamin E. Sci Rep. 2015;5:17192 pubmed publisher
  • western blot; mouse; 1:2000; fig 10
Porquet D, Andres-Benito P, Griñan-Ferré C, Camins A, Ferrer I, Canudas A, et al. Amyloid and tau pathology of familial Alzheimer's disease APP/PS1 mouse model in a senescence phenotype background (SAMP8). Age (Dordr). 2015;37:9747 pubmed publisher
  • western blot; mouse; fig 2A
Wang Z, Liu N, Liu K, Zhou G, Gan J, Wang Z, et al. Autophagy mediated CoCrMo particle-induced peri-implant osteolysis by promoting osteoblast apoptosis. Autophagy. 2015;11:2358-69 pubmed publisher
  • western blot; mouse; 1:2000; fig 6
Sun S, Shi G, Sha H, Ji Y, Han X, Shu X, et al. IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation. Nat Cell Biol. 2015;17:1546-55 pubmed publisher
  • western blot; mouse; fig 4b
Lebrun-Julien F, Suter U. Combined HDAC1 and HDAC2 Depletion Promotes Retinal Ganglion Cell Survival After Injury Through Reduction of p53 Target Gene Expression. ASN Neuro. 2015;7: pubmed publisher
  • western blot; human; 1:1000; fig  3
Tanaka T, Iino M. Sec8 regulates cytokeratin8 phosphorylation and cell migration by controlling the ERK and p38 MAPK signalling pathways. Cell Signal. 2015;27:1110-9 pubmed publisher
  • western blot; human
Ma Y, Han W, Li J, Hu L, Zhou Y. Physalin B not only inhibits the ubiquitin-proteasome pathway but also induces incomplete autophagic response in human colon cancer cells in vitro. Acta Pharmacol Sin. 2015;36:517-27 pubmed publisher
  • western blot; mouse; 1:200
Lauretti E, di Meco A, Chu J, Pratico D. Modulation of AD neuropathology and memory impairments by the isoprostane F2α is mediated by the thromboxane receptor. Neurobiol Aging. 2015;36:812-20 pubmed publisher
  • western blot; mouse
Shaw A, Pickup M, Chytil A, Aakre M, Owens P, Moses H, et al. TGFβ signaling in myeloid cells regulates mammary carcinoma cell invasion through fibroblast interactions. PLoS ONE. 2015;10:e0117908 pubmed publisher
  • western blot; rat; 1:2000
Gong G, Xiang L, Yuan L, Hu L, Wu W, Cai L, et al. Protective effect of glycyrrhizin, a direct HMGB1 inhibitor, on focal cerebral ischemia/reperfusion-induced inflammation, oxidative stress, and apoptosis in rats. PLoS ONE. 2014;9:e89450 pubmed publisher
  • western blot; human
Zhan Z, Xie X, Cao H, Zhou X, Zhang X, Fan H, et al. Autophagy facilitates TLR4- and TLR3-triggered migration and invasion of lung cancer cells through the promotion of TRAF6 ubiquitination. Autophagy. 2014;10:257-68 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Gu S, Wu W, Liu C, Yang L, Sun C, Ye W, et al. BMPRIA mediated signaling is essential for temporomandibular joint development in mice. PLoS ONE. 2014;9:e101000 pubmed publisher
  • western blot; mouse; 1:1000
Dou W, Zhang J, Ren G, Ding L, Sun A, Deng C, et al. Mangiferin attenuates the symptoms of dextran sulfate sodium-induced colitis in mice via NF-κB and MAPK signaling inactivation. Int Immunopharmacol. 2014;23:170-8 pubmed publisher
  • western blot; human
Jamal S, Cheriyan V, Muthu M, Munie S, Levi E, Ashour A, et al. CARP-1 functional mimetics are a novel class of small molecule inhibitors of malignant pleural mesothelioma cells. PLoS ONE. 2014;9:e89146 pubmed publisher
  • western blot; mouse
Komulainen E, Zdrojewska J, Freemantle E, Mohammad H, Kulesskaya N, Deshpande P, et al. JNK1 controls dendritic field size in L2/3 and L5 of the motor cortex, constrains soma size, and influences fine motor coordination. Front Cell Neurosci. 2014;8:272 pubmed publisher
  • western blot; mouse
Huang Y, Liu H, Li S, Tang Y, Wei B, Yu H, et al. MAVS-MKK7-JNK2 defines a novel apoptotic signaling pathway during viral infection. PLoS Pathog. 2014;10:e1004020 pubmed publisher
  • western blot; human
Kurz D, Payeli S, Greutert H, Briand Schumacher S, Luscher T, Tanner F. Epigenetic regulation of tissue factor inducibility in endothelial cell senescence. Mech Ageing Dev. 2014;140:1-9 pubmed publisher
  • immunohistochemistry - free floating section; rat; 1:1000
Taylor D, Moser R, Regulier E, Breuillaud L, Dixon M, Beesen A, et al. MAP kinase phosphatase 1 (MKP-1/DUSP1) is neuroprotective in Huntington's disease via additive effects of JNK and p38 inhibition. J Neurosci. 2013;33:2313-25 pubmed publisher
Cheung C, Bendris N, Paul C, Hamieh A, Anouar Y, Hahne M, et al. Cyclin A2 modulates EMT via β-catenin and phospholipase C pathways. Carcinogenesis. 2015;36:914-24 pubmed publisher
Wang Y, Wang Y, Luo M, Wu H, Kong L, Xin Y, et al. Novel curcumin analog C66 prevents diabetic nephropathy via JNK pathway with the involvement of p300/CBP-mediated histone acetylation. Biochim Biophys Acta. 2015;1852:34-46 pubmed publisher
Clarke J, Lyra e Silva N, Figueiredo C, Frozza R, Ledo J, Beckman D, et al. Alzheimer-associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation. EMBO Mol Med. 2015;7:190-210 pubmed publisher
Fraser B, Maranchuk R, Foley E. A High-Content RNAi Screen Identifies Ubiquitin Modifiers That Regulate TNF-Dependent Nuclear Accumulation of NF-κB. Front Immunol. 2014;5:322 pubmed publisher
Sun P, Zhou K, Wang S, Li P, Chen S, Lin G, et al. Involvement of MAPK/NF-κB signaling in the activation of the cholinergic anti-inflammatory pathway in experimental colitis by chronic vagus nerve stimulation. PLoS ONE. 2013;8:e69424 pubmed publisher
Kinoshita S, Krutzik P, Nolan G. COP9 signalosome component JAB1/CSN5 is necessary for T cell signaling through LFA-1 and HIV-1 replication. PLoS ONE. 2012;7:e41725 pubmed publisher
Francis S, Kramarenko I, Brandon C, Lee F, Baker T, Cunningham L. Celastrol inhibits aminoglycoside-induced ototoxicity via heat shock protein 32. Cell Death Dis. 2011;2:e195 pubmed publisher
Turner N, Das A, Warburton P, O'Regan D, Ball S, Porter K. Interleukin-1alpha stimulates proinflammatory cytokine expression in human cardiac myofibroblasts. Am J Physiol Heart Circ Physiol. 2009;297:H1117-27 pubmed publisher
Gupta S, Deepti A, Deegan S, Lisbona F, Hetz C, Samali A. HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interaction. PLoS Biol. 2010;8:e1000410 pubmed publisher
Chen J, Guo Y, Cheng W, Chen R, Liu T, Chen Z, et al. High glucose induces apoptosis and suppresses proliferation of adult rat neural stem cells following in vitro ischemia. BMC Neurosci. 2013;14:24 pubmed publisher
Bauerle K, Schweppe R, Haugen B. Inhibition of nuclear factor-kappa B differentially affects thyroid cancer cell growth, apoptosis, and invasion. Mol Cancer. 2010;9:117 pubmed publisher
McPherson V, Sharma N, Everingham S, Smith J, Zhu H, Feng G, et al. SH2 domain-containing phosphatase-2 protein-tyrosine phosphatase promotes Fc epsilon RI-induced activation of Fyn and Erk pathways leading to TNF alpha release from bone marrow-derived mast cells. J Immunol. 2009;183:4940-7 pubmed publisher
product information
SKU :
9255S
Product-Name :
Phospho-SAPK/JNK (Thr183/Tyr185) (G9) Mouse mAb
Size :
200 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R, Hm, Sc
Applications :
Flow cytometry
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
46, 54
Host :
Mouse
Target :
SAPK/JNK1 (Thr183/Tyr185) phosphate
Primary-Protein :
JNK1
Alt-Names :
JNK,JNK-46,JNK1,JNK1 alpha protein kinase,JNK1 beta protein kinase,JNK1A2,JNK21B1/2,JUN N-terminal kinase,MAP kinase 8,MAPK 8,MAPK8,MK08,Mitogen-activated protein kinase 8,PRKM8,SAPK1,Stress-activated protein kinase 1,Stress-activated protein kinase JNK1,c-Jun N-terminal kinase 1,mitogen-activated protein kinase 8 isoform JNK1 alpha1,mitogen-activated protein kinase 8 isoform JNK1 beta2,protein kinase JNK1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.