| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; mouse; 1:1000; loading ...; fig 5g
| Olcum M, Tufekci K, Durur D, Tastan B, Gokbayrak I, Genc K, et al. Ethyl Pyruvate Attenuates Microglial NLRP3 Inflammasome Activation via Inhibition of HMGB1/NF-κB/miR-223 Signaling. Antioxidants (Basel). 2021;10: pubmed publisher |
- western blot; mouse; loading ...; fig s2
| Brea R, Valdecantos P, Rada P, Alen R, García Monzón C, Bosca L, et al. Chronic treatment with acetaminophen protects against liver aging by targeting inflammation and oxidative stress. Aging (Albany NY). 2021;13:7800-7827 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 5g
| Sharifipour E, Shams S, Esmkhani M, Khodadadi J, Fotouhi Ardakani R, Koohpaei A, et al. Evaluation of bacterial co-infections of the respiratory tract in COVID-19 patients admitted to ICU. BMC Infect Dis. 2020;20:646 pubmed publisher |
- western blot; human; loading ...; fig s5h
| Koundouros N, Karali E, Tripp A, Valle A, Inglese P, Perry N, et al. Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids. Cell. 2020;181:1596-1611.e27 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 7a
| Kim K, Kim J, Kim I, Seong S, Kim N. Rev-erbα Negatively Regulates Osteoclast and Osteoblast Differentiation through p38 MAPK Signaling Pathway. Mol Cells. 2020;43:34-47 pubmed publisher |
- western blot; human; loading ...; fig ev4b
| Weiterer S, Meier Soelch J, Georgomanolis T, Mizi A, Beyerlein A, Weiser H, et al. Distinct IL-1α-responsive enhancers promote acute and coordinated changes in chromatin topology in a hierarchical manner. EMBO J. 2019;:e101533 pubmed publisher |
- western blot; mouse; fig 8a
- western blot; Pseudomonas aeruginosa; loading ...; fig 8a
| Pang Z, Raudonis R, McCormick C, Cheng Z. Early Growth Response 1 Deficiency Protects the Host against Pseudomonas aeruginosa Lung Infection. Infect Immun. 2019;88: pubmed publisher |
- western blot; human; loading ...; fig s2g
| Zierhut C, Yamaguchi N, Paredes M, Luo J, Carroll T, Funabiki H. The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death. Cell. 2019;178:302-315.e23 pubmed publisher |
- western blot; mouse; loading ...; fig s8a
| Guo M, Hartlova A, Gierlinski M, Prescott A, Castellvi J, Losa J, et al. Triggering MSR1 promotes JNK-mediated inflammation in IL-4-activated macrophages. EMBO J. 2019;38: pubmed publisher |
- western blot; human; 1:1000; loading ...; fig s1
| Kanmani P, Ansari A, Villena J, Kim H. Immunobiotics Beneficially Modulate TLR4 Signaling Triggered by Lipopolysaccharide and Reduce Hepatic Steatosis In Vitro. J Immunol Res. 2019;2019:3876896 pubmed publisher |
- western blot; mouse; 1 ug/ml; loading ...; fig s9a
| Sweere J, Van Belleghem J, Ishak H, Bach M, Popescu M, Sunkari V, et al. Bacteriophage trigger antiviral immunity and prevent clearance of bacterial infection. Science. 2019;363: pubmed publisher |
- western blot; mouse; loading ...; fig 4b, 6e
| Chen L, Kong L, Wei X, Wang Y, Wang B, Zhang X, et al. β-arrestin 2 negatively regulates NOD2 signalling pathway through association with TRAF6 in microglia after cerebral ischaemia/reperfusion injury. J Cell Mol Med. 2019;23:3325-3335 pubmed publisher |
- western blot; human; loading ...; fig 6d
| Lee S, North K, Kim E, Jang E, Obeng E, Lu S, et al. Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations. Cancer Cell. 2018;34:225-241.e8 pubmed publisher |
- western blot; mouse; loading ...; fig 1h
| Li F, Li Y, Liang H, Xu T, Kong Y, Huang M, et al. HECTD3 mediates TRAF3 polyubiquitination and type I interferon induction during bacterial infection. J Clin Invest. 2018;128:4148-4162 pubmed publisher |
- western blot; mouse; loading ...
| Peltzer N, Darding M, Montinaro A, Dráber P, Draberova H, Kupka S, et al. LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis. Nature. 2018;557:112-117 pubmed publisher |
- western blot; rat; loading ...; fig 7a
| Miyasato Y, Yoshizawa T, Sato Y, Nakagawa T, Miyasato Y, Kakizoe Y, et al. Sirtuin 7 Deficiency Ameliorates Cisplatin-induced Acute Kidney Injury Through Regulation of the Inflammatory Response. Sci Rep. 2018;8:5927 pubmed publisher |
- western blot; mouse; 1:1000; fig 3e
| Giampazolias E, Zunino B, Dhayade S, Bock F, Cloix C, Cao K, et al. Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency. Nat Cell Biol. 2017;19:1116-1129 pubmed publisher |
- western blot; mouse; fig s5b
| Bae S, Lee M, Mun S, Giannopoulou E, Yong Gonzalez V, Cross J, et al. MYC-dependent oxidative metabolism regulates osteoclastogenesis via nuclear receptor ERR?. J Clin Invest. 2017;127:2555-2568 pubmed publisher |
- western blot; human; loading ...; fig 7a
- western blot; mouse; loading ...; fig EV3d
| Lafont E, Kantari Mimoun C, Dráber P, De Miguel D, Hartwig T, Reichert M, et al. The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death. EMBO J. 2017;36:1147-1166 pubmed publisher |
- western blot; mouse; loading ...; fig 2a
- western blot; human; loading ...; fig 1a
| Shibata Y, Tokunaga F, Goto E, Komatsu G, Gohda J, Saeki Y, et al. HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains. PLoS Pathog. 2017;13:e1006162 pubmed publisher |
- western blot; mouse; 1:500; fig 3a
| Luo L, Bokil N, Wall A, Kapetanovic R, Lansdaal N, Marceline F, et al. SCIMP is a transmembrane non-TIR TLR adaptor that promotes proinflammatory cytokine production from macrophages. Nat Commun. 2017;8:14133 pubmed publisher |
- western blot; mouse; loading ...; fig s3h, s4a
| Newton K, Wickliffe K, Maltzman A, Dugger D, Strasser A, Pham V, et al. RIPK1 inhibits ZBP1-driven necroptosis during development. Nature. 2016;540:129-133 pubmed publisher |
- western blot; human; loading ...; fig 5
| Guan S, Zhao Y, Lu J, Yu Y, Sun W, Mao X, et al. Second-generation proteasome inhibitor carfilzomib sensitizes neuroblastoma cells to doxorubicin-induced apoptosis. Oncotarget. 2016;7:75914-75925 pubmed publisher |
- western blot; human; loading ...; fig 3a
| Ding S, Mooney N, Li B, Kelly M, Feng N, Loktev A, et al. Comparative Proteomics Reveals Strain-Specific β-TrCP Degradation via Rotavirus NSP1 Hijacking a Host Cullin-3-Rbx1 Complex. PLoS Pathog. 2016;12:e1005929 pubmed publisher |
- western blot; human; 1:200; fig st1
| Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher |
- western blot; human; loading ...; fig 6a
| Shi Y, Yu Y, Wang Z, Wang H, Bieerkehazhi S, Zhao Y, et al. Second-generation proteasome inhibitor carfilzomib enhances doxorubicin-induced cytotoxicity and apoptosis in breast cancer cells. Oncotarget. 2016;7:73697-73710 pubmed publisher |
- western blot; human; loading ...; fig 7c
| Zhang X, Zheng Z, Liu X, Shu B, Mao P, Bai B, et al. Tick-borne encephalitis virus induces chemokine RANTES expression via activation of IRF-3 pathway. J Neuroinflammation. 2016;13:209 pubmed publisher |
- western blot; human; fig 1
| Zhou Q, Yu X, Demirkaya E, Deuitch N, Stone D, Tsai W, et al. Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease. Proc Natl Acad Sci U S A. 2016;113:10127-32 pubmed publisher |
- western blot; human; fig 5
| Kupka S, De Miguel D, Dráber P, Martino L, Surinova S, Rittinger K, et al. SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes. Cell Rep. 2016;16:2271-80 pubmed publisher |
- western blot; human; 1:5000; fig 5
- western blot; mouse; 1:5000; fig 5
| Pourcelot M, Zemirli N, Silva da Costa L, Loyant R, Garcin D, Vitour D, et al. The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing. BMC Biol. 2016;14:69 pubmed publisher |
- western blot; mouse; fig 6
| Damgaard R, Walker J, Marco Casanova P, Morgan N, Titheradge H, Elliott P, et al. The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity. Cell. 2016;166:1215-1230.e20 pubmed publisher |
- western blot; human; fig 6
| Huang L, Stuart C, Takeda K, D Agnillo F, Golding B. Poly(I:C) Induces Human Lung Endothelial Barrier Dysfunction by Disrupting Tight Junction Expression of Claudin-5. PLoS ONE. 2016;11:e0160875 pubmed publisher |
| Kawamoto E, Koshinaka K, Yoshimura T, Masuda H, Kawanaka K. Immobilization rapidly induces muscle insulin resistance together with the activation of MAPKs (JNK and p38) and impairment of AS160 phosphorylation. Physiol Rep. 2016;4: pubmed publisher |
- western blot; human; loading ...; fig 4a
| Ciaraldi T, Ryan A, Mudaliar S, Henry R. Altered Myokine Secretion Is an Intrinsic Property of Skeletal Muscle in Type 2 Diabetes. PLoS ONE. 2016;11:e0158209 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 7c
- western blot; mouse; 1:1000; loading ...; fig 4a
| Kreger B, Dougherty A, Greene K, Cerione R, Antonyak M. Microvesicle Cargo and Function Changes upon Induction of Cellular Transformation. J Biol Chem. 2016;291:19774-85 pubmed publisher |
- western blot; mouse; loading ...; fig s9
| Rackov G, Hernandez Jimenez E, Shokri R, Carmona Rodríguez L, Manes S, Alvarez Mon M, et al. p21 mediates macrophage reprogramming through regulation of p50-p50 NF-?B and IFN-?. J Clin Invest. 2016;126:3089-103 pubmed publisher |
- western blot; rat; 1:1000; fig 5
| Li X, Chen Y, Wang L, Shang G, Zhang C, Zhao Z, et al. Quercetin alleviates pulmonary angiogenesis in a rat model of hepatopulmonary syndrome. Braz J Med Biol Res. 2016;49: pubmed publisher |
- western blot; mouse; fig 4
| Ahmad F, Chung Y, Tang Y, Hockman S, Liu S, Khan Y, et al. Phosphodiesterase 3B (PDE3B) regulates NLRP3 inflammasome in adipose tissue. Sci Rep. 2016;6:28056 pubmed publisher |
- western blot; human; tbl 1
| Wagner S, Satpathy S, Beli P, Choudhary C. SPATA2 links CYLD to the TNF-? receptor signaling complex and modulates the receptor signaling outcomes. EMBO J. 2016;35:1868-84 pubmed publisher |
- western blot; mouse; 1:500; loading ...; fig 3d
| Kinsella S, König H, Prehn J. Bid Promotes K63-Linked Polyubiquitination of Tumor Necrosis Factor Receptor Associated Factor 6 (TRAF6) and Sensitizes to Mutant SOD1-Induced Proinflammatory Signaling in Microglia. Eneuro. 2016;3: pubmed publisher |
- western blot; human; fig 5
| Hein A, Post C, Sheinin Y, Lakshmanan I, Natarajan A, Enke C, et al. RAC1 GTPase promotes the survival of breast cancer cells in response to hyper-fractionated radiation treatment. Oncogene. 2016;35:6319-6329 pubmed publisher |
- western blot; human; 1:1000; fig 2
| Douanne T, Gavard J, Bidère N. The paracaspase MALT1 cleaves the LUBAC subunit HOIL1 during antigen receptor signaling. J Cell Sci. 2016;129:1775-80 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 3d
| Kawano M, Tanaka K, Itonaga I, Iwasaki T, Miyazaki M, Ikeda S, et al. Dendritic cells combined with doxorubicin induces immunogenic cell death and exhibits antitumor effects for osteosarcoma. Oncol Lett. 2016;11:2169-2175 pubmed |
- western blot; mouse; fig 3
| Barroso González J, Auclair S, Luan S, Thomas L, Atkins K, Aslan J, et al. PACS-2 mediates the ATM and NF-κB-dependent induction of anti-apoptotic Bcl-xL in response to DNA damage. Cell Death Differ. 2016;23:1448-57 pubmed publisher |
- western blot; mouse; loading ...; fig 5a
| Naik E, Dixit V. Usp9X Is Required for Lymphocyte Activation and Homeostasis through Its Control of ZAP70 Ubiquitination and PKCβ Kinase Activity. J Immunol. 2016;196:3438-51 pubmed publisher |
- western blot; mouse; fig 8
| Jean Charles P, Zhang L, Wu J, Han S, Brian L, Freedman N, et al. Ubiquitin-specific Protease 20 Regulates the Reciprocal Functions of β-Arrestin2 in Toll-like Receptor 4-promoted Nuclear Factor κB (NFκB) Activation. J Biol Chem. 2016;291:7450-64 pubmed publisher |
- western blot; human; fig 2
| Schirmer M, Trentin L, Queudeville M, Seyfried F, Demir S, Tausch E, et al. Intrinsic and chemo-sensitizing activity of SMAC-mimetics on high-risk childhood acute lymphoblastic leukemia. Cell Death Dis. 2016;7:e2052 pubmed publisher |
- western blot; mouse; loading ...; fig 7d
| Chen Y, Zheng Y, You X, Yu M, Fu G, Su X, et al. Kras Is Critical for B Cell Lymphopoiesis. J Immunol. 2016;196:1678-85 pubmed publisher |
- western blot; mouse; fig 5
| Kaizuka T, Mizushima N. Atg13 Is Essential for Autophagy and Cardiac Development in Mice. Mol Cell Biol. 2016;36:585-95 pubmed publisher |
- western blot; human; loading ...; fig 2b
| Alquézar C, de la Encarnación A, Moreno F, López de Munain A, MartÃn Requero Ã. Progranulin deficiency induces overactivation of WNT5A expression via TNF-α/NF-κB pathway in peripheral cells from frontotemporal dementia-linked granulin mutation carriers. J Psychiatry Neurosci. 2016;41:225-39 pubmed |
- western blot; human; fig 2
| Wu W, Chen Q, Geng F, Tong L, Yang R, Yang J, et al. Calcineurin B stimulates cytokine production through a CD14-independent Toll-like receptor 4 pathway. Immunol Cell Biol. 2016;94:285-92 pubmed publisher |
| Caballero I, Boyd J, Almiñana C, Sánchez López J, Basatvat S, Montazeri M, et al. Understanding the dynamics of Toll-like Receptor 5 response to flagellin and its regulation by estradiol. Sci Rep. 2017;7:40981 pubmed publisher |
| Ihn H, Lee T, Kim J, Lee D, Kim N, Shin H, et al. OCLI-023, a Novel Pyrimidine Compound, Suppresses Osteoclastogenesis In Vitro and Alveolar Bone Resorption In Vivo. PLoS ONE. 2017;12:e0170159 pubmed publisher |
| Lewis A, Dunleavy K, Senkow T, Her C, Horn B, Jersett M, et al. Oxidation increases the strength of the methionine-aromatic interaction. Nat Chem Biol. 2016;12:860-6 pubmed publisher |
| Shen X, Wu Z, Chen S, Chen Y, Xia J, Lv Y, et al. Induction of G2/M phase arrest and apoptosis by ZGDHU-1 in A549 and RERF-LC-MA lung cancer cells. Oncol Lett. 2016;12:989-994 pubmed |
| Ankers J, Awais R, Jones N, Boyd J, Ryan S, Adamson A, et al. Dynamic NF-κB and E2F interactions control the priority and timing of inflammatory signalling and cell proliferation. elife. 2016;5: pubmed publisher |
| Verhoeven R, Tong S, Zhang G, Zong J, Chen Y, Jin D, et al. NF-κB Signaling Regulates Expression of Epstein-Barr Virus BART MicroRNAs and Long Noncoding RNAs in Nasopharyngeal Carcinoma. J Virol. 2016;90:6475-88 pubmed publisher |
| Takagi H, Arimura K, Uto T, Fukaya T, Nakamura T, Choijookhuu N, et al. Plasmacytoid dendritic cells orchestrate TLR7-mediated innate and adaptive immunity for the initiation of autoimmune inflammation. Sci Rep. 2016;6:24477 pubmed publisher |
| Du Q, Wang Y, Liu C, Wang H, Fan H, Li Y, et al. Chemopreventive activity of GEN-27, a genistein derivative, in colitis-associated cancer is mediated by p65-CDX2-β-catenin axis. Oncotarget. 2016;7:17870-84 pubmed publisher |
| Zhou Q, Wang H, Schwartz D, Stoffels M, Park Y, Zhang Y, et al. Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease. Nat Genet. 2016;48:67-73 pubmed publisher |
