product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Bad (D24A9) Rabbit mAb
catalog :
9239
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
D24A9
reactivity :
human, mouse, rat
application :
western blot
citations: 22
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig s3i
He M, Chaurushiya M, Webster J, Kummerfeld S, Reja R, Chaudhuri S, et al. Intrinsic apoptosis shapes the tumor spectrum linked to inactivation of the deubiquitinase BAP1. Science. 2019;364:283-285 pubmed publisher
  • western blot; mouse; 1:1000; fig 7
Swamy M, Pathak S, Grzes K, Damerow S, Sinclair L, van Aalten D, et al. Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy. Nat Immunol. 2016;17:712-20 pubmed publisher
  • western blot; mouse; 1:1000; tbl 1
Guillot F, Kemppainen S, Lavasseur G, Miettinen P, Laroche S, Tanila H, et al. Brain-Specific Basal and Novelty-Induced Alternations in PI3K-Akt and MAPK/ERK Signaling in a Middle-Aged AβPP/PS1 Mouse Model of Alzheimer's Disease. J Alzheimers Dis. 2016;51:1157-73 pubmed publisher
  • western blot; human; 1:1000; fig 1
Yu L, Wu W, Gu C, Zhong D, Zhao X, Kong Y, et al. Obatoclax impairs lysosomal function to block autophagy in cisplatin-sensitive and -resistant esophageal cancer cells. Oncotarget. 2016;7:14693-707 pubmed publisher
  • western blot; human; 1:1000; fig s1
Qiu Z, Sun R, Mo X, Li W. The p70S6K Specific Inhibitor PF-4708671 Impedes Non-Small Cell Lung Cancer Growth. PLoS ONE. 2016;11:e0147185 pubmed publisher
  • western blot; human; fig 5
Wang F, Feng Y, Li P, Wang K, Feng L, Liu Y, et al. RASSF10 is an epigenetically inactivated tumor suppressor and independent prognostic factor in hepatocellular carcinoma. Oncotarget. 2016;7:4279-97 pubmed publisher
  • western blot; mouse; fig 4
Hukelmann J, Anderson K, Sinclair L, Grzes K, Murillo A, Hawkins P, et al. The cytotoxic T cell proteome and its shaping by the kinase mTOR. Nat Immunol. 2016;17:104-12 pubmed publisher
  • western blot; human; 1:1000; fig 1
Kreuz S, Holmes K, Tooze R, Lefevre P. Loss of PIM2 enhances the anti-proliferative effect of the pan-PIM kinase inhibitor AZD1208 in non-Hodgkin lymphomas. Mol Cancer. 2015;14:205 pubmed publisher
  • western blot; human
Rayavarapu R, Heiden B, Pagani N, Shaw M, Shuff S, Zhang S, et al. The role of multicellular aggregation in the survival of ErbB2-positive breast cancer cells during extracellular matrix detachment. J Biol Chem. 2015;290:8722-33 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 1A
Xia J, Chen S, Lv Y, Lu L, Hu W, Zhou Y. ZGDHu-1 induces Gâ‚‚/M phase arrest and apoptosis in Kasumi-1 cells. Mol Med Rep. 2015;11:3398-404 pubmed publisher
  • western blot; human; fig 5
Valianou M, Cox A, Pichette B, Hartley S, Paladhi U, Astrinidis A. Pharmacological inhibition of Polo-like kinase 1 (PLK1) by BI-2536 decreases the viability and survival of hamartin and tuberin deficient cells via induction of apoptosis and attenuation of autophagy. Cell Cycle. 2015;14:399-407 pubmed publisher
  • western blot; mouse
Liu E, Zalutskaya A, Chae B, Zhu E, Gori F, Demay M. Phosphate interacts with PTHrP to regulate endochondral bone formation. Endocrinology. 2014;155:3750-6 pubmed publisher
  • western blot; human
Pavet V, Shlyakhtina Y, He T, Ceschin D, Kohonen P, Perala M, et al. Plasminogen activator urokinase expression reveals TRAIL responsiveness and supports fractional survival of cancer cells. Cell Death Dis. 2014;5:e1043 pubmed publisher
  • western blot; mouse
Crowther A, Gama V, Bevilacqua A, Chang S, Yuan H, Deshmukh M, et al. Tonic activation of Bax primes neural progenitors for rapid apoptosis through a mechanism preserved in medulloblastoma. J Neurosci. 2013;33:18098-108 pubmed publisher
  • western blot; human; 1:1000
Geissler A, Haun F, Frank D, Wieland K, Simon M, Idzko M, et al. Apoptosis induced by the fungal pathogen gliotoxin requires a triple phosphorylation of Bim by JNK. Cell Death Differ. 2013;20:1317-29 pubmed publisher
  • western blot; human
Lu J, Zavorotinskaya T, Dai Y, Niu X, Castillo J, Sim J, et al. Pim2 is required for maintaining multiple myeloma cell growth through modulating TSC2 phosphorylation. Blood. 2013;122:1610-20 pubmed publisher
Rajesh Y, Biswas A, Kumar U, Das S, Banerjee I, Banik P, et al. Targeting NFE2L2, a transcription factor upstream of MMP-2: A potential therapeutic strategy for temozolomide resistant glioblastoma. Biochem Pharmacol. 2019;164:1-16 pubmed publisher
Yang W, Cho H, Shin H, Chung J, Kang E, Lee E, et al. Accumulation of cytoplasmic Cdk1 is associated with cancer growth and survival rate in epithelial ovarian cancer. Oncotarget. 2016;7:49481-49497 pubmed publisher
Zhang Q, Ma S, Liu B, Liu J, Zhu R, Li M. Chrysin induces cell apoptosis via activation of the p53/Bcl-2/caspase-9 pathway in hepatocellular carcinoma cells. Exp Ther Med. 2016;12:469-474 pubmed
Lindhurst M, Yourick M, Yu Y, Savage R, Ferrari D, Biesecker L. Repression of AKT signaling by ARQ 092 in cells and tissues from patients with Proteus syndrome. Sci Rep. 2015;5:17162 pubmed publisher
Li T, Zhang Q, Zhang J, Yang G, Shao Z, Luo J, et al. Fenofibrate induces apoptosis of triple-negative breast cancer cells via activation of NF-?B pathway. BMC Cancer. 2014;14:96 pubmed publisher
Gao Z, Liu F, Yin P, Wan C, He S, Liu X, et al. Inhibition of heat-induced apoptosis in rat small intestine and IEC-6 cells through the AKT signaling pathway. BMC Vet Res. 2013;9:241 pubmed publisher
product information
SKU :
9239S
Product-Name :
Bad (D24A9) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Western blot
Product-Category :
Apoptosis
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
23
Host :
Rabbit
Target :
Bad
Primary-Protein :
BAD
Alt-Names :
BAD,BBC2,BBC6,BCL-X/BCL-2 binding protein,BCL2-antagonist of cell death protein,BCL2-associated agonist of cell death,BCL2-binding component 6,BCL2-binding protein,BCL2L8,Bcl-2-binding component 6,Bcl-2-like protein 8,Bcl-XL/Bcl-2-associated death promoter,Bcl2 antagonist of cell death,Bcl2-L-8
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.