product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-p38 MAPK (Thr180/Tyr182) (28B10) Mouse mAb
catalog :
9216
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
antigen modification :
phosphorylated
clone name :
28B10
reactivity :
human, mouse, rat, dogs, pigs
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 98
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 4a
Hering L, Katkeviciute E, Schwarzfischer M, Niechcial A, Riggs J, Wawrzyniak M, et al. Macrophages Compensate for Loss of Protein Tyrosine Phosphatase N2 in Dendritic Cells to Protect from Elevated Colitis. Int J Mol Sci. 2021;22: pubmed publisher
  • western blot; mouse; 1:200; loading ...; fig s3
Emre C, Do K, Jun B, Hjorth E, Alcalde S, Kautzmann M, et al. Age-related changes in brain phospholipids and bioactive lipids in the APP knock-in mouse model of Alzheimer's disease. Acta Neuropathol Commun. 2021;9:116 pubmed publisher
  • western blot; human; 1:700; loading ...; fig 6
Lee J, Hsu Y, Li Y, Cheng S. Galectin-3 Inhibitors Suppress Anoikis Resistance and Invasive Capacity in Thyroid Cancer Cells. Int J Endocrinol. 2021;2021:5583491 pubmed publisher
  • flow cytometry; human; loading ...; fig 6b
Sun R, Hedl M, Abraham C. TNFSF15 Promotes Antimicrobial Pathways in Human Macrophages and These Are Modulated by TNFSF15 Disease-Risk Variants. Cell Mol Gastroenterol Hepatol. 2021;11:249-272 pubmed publisher
  • western blot; mouse; loading ...; fig s4a
Li X, Zhang M, Huang X, Liang W, Li G, Lu X, et al. Ubiquitination of RIPK1 regulates its activation mediated by TNFR1 and TLRs signaling in distinct manners. Nat Commun. 2020;11:6364 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 4d
  • western blot; mouse; loading ...; fig 4b
Xiang S, Chen K, Xu L, Wang T, Guo C. Bergenin Exerts Hepatoprotective Effects by Inhibiting the Release of Inflammatory Factors, Apoptosis and Autophagy via the PPAR-γ Pathway. Drug Des Devel Ther. 2020;14:129-143 pubmed publisher
  • western blot; rat; 1:500; loading ...; fig 4f
Wang H, Wei Y, Pu Y, Jiang D, Jiang X, Zhang Y, et al. Brain-derived neurotrophic factor stimulation of T-type Ca2+ channels in sensory neurons contributes to increased peripheral pain sensitivity. Sci Signal. 2019;12: pubmed publisher
  • western blot; mouse; 1:2500; loading ...; fig 3a, 3c, s3d
Liu Z, Wu C, Pan Y, Liu H, Wang X, Yang Y, et al. NDR2 promotes the antiviral immune response via facilitating TRIM25-mediated RIG-I activation in macrophages. Sci Adv. 2019;5:eaav0163 pubmed publisher
  • western blot; mouse; loading ...; fig s4b
Grohmann M, Wiede F, Dodd G, Gurzov E, Ooi G, Butt T, et al. Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC. Cell. 2018;175:1289-1306.e20 pubmed publisher
  • western blot; mouse; 1:2500; loading ...; fig s4a
Liu Z, Qin Q, Wu C, Li H, Shou J, Yang Y, et al. Downregulated NDR1 protein kinase inhibits innate immune response by initiating an miR146a-STAT1 feedback loop. Nat Commun. 2018;9:2789 pubmed publisher
  • western blot; mouse; 1:1000; loading ...
Gautam J, Nirwane A, Yao Y. Laminin differentially regulates the stemness of type I and type II pericytes. Stem Cell Res Ther. 2017;8:28 pubmed publisher
  • western blot; mouse; 1:2000; loading ...; fig s3
Lim E, Nakanishi S, Hoghooghi V, Eaton S, Palmer A, Frederick A, et al. AlphaB-crystallin regulates remyelination after peripheral nerve injury. Proc Natl Acad Sci U S A. 2017;114:E1707-E1716 pubmed publisher
  • western blot; mouse; loading ...; fig 4c
Schwarz F, Landig C, Siddiqui S, Secundino I, Olson J, Varki N, et al. Paired Siglec receptors generate opposite inflammatory responses to a human-specific pathogen. EMBO J. 2017;36:751-760 pubmed publisher
  • western blot; human; loading ...; fig 2c
Wamsley J, Issaeva N, An H, Lu X, Donehower L, Yarbrough W. LZAP is a novel Wip1 binding partner and positive regulator of its phosphatase activity in vitro. Cell Cycle. 2017;16:213-223 pubmed publisher
  • western blot; mouse; loading ...; fig 8b
Lee H, Khan S, Khaliqdina S, Altintas M, Grahammer F, Zhao J, et al. Absence of miR-146a in Podocytes Increases Risk of Diabetic Glomerulopathy via Up-regulation of ErbB4 and Notch-1. J Biol Chem. 2017;292:732-747 pubmed publisher
  • western blot; mouse; fig s7b
Han J, Bae J, Choi C, Choi S, Kang H, Jo E, et al. Autophagy induced by AXL receptor tyrosine kinase alleviates acute liver injury via inhibition of NLRP3 inflammasome activation in mice. Autophagy. 2016;12:2326-2343 pubmed
  • immunohistochemistry; mouse; loading ...; fig s10b
Thamodaran V, Bruce A. p38 (Mapk14/11) occupies a regulatory node governing entry into primitive endoderm differentiation during preimplantation mouse embryo development. Open Biol. 2016;6: pubmed publisher
  • flow cytometry; human; loading ...; fig s18a
Kagoya Y, Nakatsugawa M, Yamashita Y, Ochi T, Guo T, Anczurowski M, et al. BET bromodomain inhibition enhances T cell persistence and function in adoptive immunotherapy models. J Clin Invest. 2016;126:3479-94 pubmed publisher
  • western blot; rat; fig 4
Kawamoto E, Koshinaka K, Yoshimura T, Masuda H, Kawanaka K. Immobilization rapidly induces muscle insulin resistance together with the activation of MAPKs (JNK and p38) and impairment of AS160 phosphorylation. Physiol Rep. 2016;4: pubmed publisher
  • western blot; human; loading ...; fig 4a
Ciaraldi T, Ryan A, Mudaliar S, Henry R. Altered Myokine Secretion Is an Intrinsic Property of Skeletal Muscle in Type 2 Diabetes. PLoS ONE. 2016;11:e0158209 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 3c
Abdelbaset Ismail A, Borkowska Rzeszotek S, Kubis E, Bujko K, Brzeźniakiewicz Janus K, Bolkun L, et al. Activation of the complement cascade enhances motility of leukemic cells by downregulating expression of HO-1. Leukemia. 2017;31:446-458 pubmed publisher
  • immunocytochemistry; mouse; 1:50; fig 3g
Rozo M, Li L, Fan C. Targeting ?1-integrin signaling enhances regeneration in aged and dystrophic muscle in mice. Nat Med. 2016;22:889-96 pubmed publisher
  • western blot; human; 1:250; loading ...; fig 6a
Heckler M, Zeleke T, Divekar S, Fernandez A, Tiek D, Woodrick J, et al. Antimitotic activity of DY131 and the estrogen-related receptor beta 2 (ERRβ2) splice variant in breast cancer. Oncotarget. 2016;7:47201-47220 pubmed publisher
  • western blot; mouse; fig 1
Tortola L, Nitsch R, Bertrand M, Kogler M, Redouane Y, Kozieradzki I, et al. The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate. Cell Rep. 2016;15:1481-1492 pubmed publisher
  • immunohistochemistry; rat; 1:100; fig 6
Foxton R, Osborne A, Martin K, Ng Y, Shima D. Distal retinal ganglion cell axon transport loss and activation of p38 MAPK stress pathway following VEGF-A antagonism. Cell Death Dis. 2016;7:e2212 pubmed publisher
  • western blot; human; fig 5
Pecháčková S, Burdova K, Benada J, Kleiblova P, Jenikova G, Macurek L. Inhibition of WIP1 phosphatase sensitizes breast cancer cells to genotoxic stress and to MDM2 antagonist nutlin-3. Oncotarget. 2016;7:14458-75 pubmed publisher
  • western blot; rat; fig 3
Hong M, Nam K, Kim K, Kim S, Kim I. The small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha. Cell Stress Chaperones. 2016;21:485-97 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig s10f
Demetriades C, Plescher M, Teleman A. Lysosomal recruitment of TSC2 is a universal response to cellular stress. Nat Commun. 2016;7:10662 pubmed publisher
  • western blot; mouse; loading ...; fig 7d
Chen Y, Zheng Y, You X, Yu M, Fu G, Su X, et al. Kras Is Critical for B Cell Lymphopoiesis. J Immunol. 2016;196:1678-85 pubmed publisher
  • western blot; human; fig 2
Waye S, Naeem A, Choudhry M, Parasido E, Tricoli L, Sivakumar A, et al. The p53 tumor suppressor protein protects against chemotherapeutic stress and apoptosis in human medulloblastoma cells. Aging (Albany NY). 2015;7:854-68 pubmed
  • western blot; rat; 1:1000; fig 5a
Li W, Wei S, Liu C, Song M, Wu H, Yang Y. Regulation of the osteogenic and adipogenic differentiation of bone marrow-derived stromal cells by extracellular uridine triphosphate: The role of P2Y2 receptor and ERK1/2 signaling. Int J Mol Med. 2016;37:63-73 pubmed publisher
  • western blot; rat; fig 7
Zhu X, Wang K, Zhang K, Tan X, Wu Z, Sun S, et al. Tetramethylpyrazine Protects Retinal Capillary Endothelial Cells (TR-iBRB2) against IL-1β-Induced Nitrative/Oxidative Stress. Int J Mol Sci. 2015;16:21775-90 pubmed publisher
  • western blot; mouse; 1:1000; fig 4
Plescher M, Teleman A, Demetriades C. TSC2 mediates hyperosmotic stress-induced inactivation of mTORC1. Sci Rep. 2015;5:13828 pubmed publisher
  • western blot; human
Bunaciu R, Jensen H, Macdonald R, Latocha D, Varner J, Yen A. 6-Formylindolo(3,2-b)Carbazole (FICZ) Modulates the Signalsome Responsible for RA-Induced Differentiation of HL-60 Myeloblastic Leukemia Cells. PLoS ONE. 2015;10:e0135668 pubmed publisher
  • western blot; mouse; fig s5
Zhang Q, Zhao K, Shen Q, Han Y, Gu Y, Li X, et al. Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6. Nature. 2015;525:389-393 pubmed publisher
  • western blot; human
Picot N, Guerrette R, Beauregard A, Jean S, Michaud P, Harquail J, et al. Mammaglobin 1 promotes breast cancer malignancy and confers sensitivity to anticancer drugs. Mol Carcinog. 2016;55:1150-62 pubmed publisher
  • western blot; mouse; fig 6
Ito A, Hong C, Rong X, Zhu X, Tarling E, Hedde P, et al. LXRs link metabolism to inflammation through Abca1-dependent regulation of membrane composition and TLR signaling. elife. 2015;4:e08009 pubmed publisher
  • western blot; mouse; 1:1000; fig 5
Wu C, Jiao H, Lai Y, Zheng W, Chen K, Qu H, et al. Kindlin-2 controls TGF-β signalling and Sox9 expression to regulate chondrogenesis. Nat Commun. 2015;6:7531 pubmed publisher
  • western blot; human; fig 5
Zhao L, Liu S, Che X, Hou K, Ma Y, Li C, et al. Bufalin inhibits TGF-β-induced epithelial-to-mesenchymal transition and migration in human lung cancer A549 cells by downregulating TGF-β receptors. Int J Mol Med. 2015;36:645-52 pubmed publisher
  • western blot; human; fig s8
Luan Q, Jin L, Jiang C, Tay K, Lai F, Liu X, et al. RIPK1 regulates survival of human melanoma cells upon endoplasmic reticulum stress through autophagy. Autophagy. 2015;11:975-94 pubmed publisher
  • western blot; human; loading ...; fig 4
Sun L, Xu C, Chen G, Yu M, Yang S, Qiu Y, et al. A Novel Role of OS-9 in the Maintenance of Intestinal Barrier Function from Hypoxia-induced Injury via p38-dependent Pathway. Int J Biol Sci. 2015;11:664-71 pubmed publisher
  • western blot; mouse; fig 1
Lee E, Park E, Mun H, Chang E, Ko J, Kim D, et al. Soluble receptor for advanced glycation end products inhibits disease progression in autosomal dominant polycystic kidney disease by down-regulating cell proliferation. FASEB J. 2015;29:3506-14 pubmed publisher
  • western blot; mouse; 1:1000; fig s2
Wilson C, Jurk D, Fullard N, Banks P, Page A, Luli S, et al. NFκB1 is a suppressor of neutrophil-driven hepatocellular carcinoma. Nat Commun. 2015;6:6818 pubmed publisher
  • western blot; mouse; 1:1000; fig s4
Chen W, Wu J, Li L, Zhang Z, Ren J, Liang Y, et al. Ppm1b negatively regulates necroptosis through dephosphorylating Rip3. Nat Cell Biol. 2015;17:434-44 pubmed publisher
  • western blot; human
Kurz D, Payeli S, Greutert H, Briand Schumacher S, Luscher T, Tanner F. Epigenetic regulation of tissue factor inducibility in endothelial cell senescence. Mech Ageing Dev. 2014;140:1-9 pubmed publisher
  • western blot; human; 1:200
Chondrogiannis G, Kastamoulas M, Kanavaros P, Vartholomatos G, Bai M, Baltogiannis D, et al. Cytokine effects on cell viability and death of prostate carcinoma cells. Biomed Res Int. 2014;2014:536049 pubmed publisher
  • western blot; dogs
Enjoji S, Ohama T, Sato K. Regulation of epithelial cell tight junctions by protease-activated receptor 2. J Vet Med Sci. 2014;76:1225-9 pubmed
  • western blot; human
Wang Q, Shen B, Chen L, Zheng P, Feng H, Hao Q, et al. Extracellular calumenin suppresses ERK1/2 signaling and cell migration by protecting fibulin-1 from MMP-13-mediated proteolysis. Oncogene. 2015;34:1006-18 pubmed publisher
  • flow cytometry; mouse
  • immunocytochemistry; mouse; 1:50
Bernet J, Doles J, Hall J, Kelly Tanaka K, Carter T, Olwin B. p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice. Nat Med. 2014;20:265-71 pubmed publisher
  • western blot; mouse
Park E, Kim B, Lee E, Chang E, Kim D, Choi S, et al. Targeting of receptor for advanced glycation end products suppresses cyst growth in polycystic kidney disease. J Biol Chem. 2014;289:9254-62 pubmed publisher
  • western blot; mouse; fig 1e
Shin Y, Huh Y, Kim K, Kim S, Park K, Koh J, et al. Low-density lipoprotein receptor-related protein 5 governs Wnt-mediated osteoarthritic cartilage destruction. Arthritis Res Ther. 2014;16:R37 pubmed publisher
  • western blot; mouse; 1:200
Bittner S, Ruck T, Schuhmann M, Herrmann A, Moha Ou Maati H, Bobak N, et al. Endothelial TWIK-related potassium channel-1 (TREK1) regulates immune-cell trafficking into the CNS. Nat Med. 2013;19:1161-5 pubmed publisher
  • western blot; pigs
Moberly S, Mather K, Berwick Z, Owen M, Goodwill A, Casalini E, et al. Impaired cardiometabolic responses to glucagon-like peptide 1 in obesity and type 2 diabetes mellitus. Basic Res Cardiol. 2013;108:365 pubmed publisher
  • western blot; human
Zhou X, Wang H, Burg M, Ferraris J. High NaCl-induced inhibition of PTG contributes to activation of NFAT5 through attenuation of the negative effect of SHP-1. Am J Physiol Renal Physiol. 2013;305:F362-9 pubmed publisher
Ranjan K, Hedl M, Sinha S, Zhang X, Abraham C. Ubiquitination of ATF6 by disease-associated RNF186 promotes the innate receptor-induced unfolded protein response. J Clin Invest. 2021;131: pubmed publisher
Ethaeb A, Mohammad M, Madkhali Y, Featherby S, Maraveyas A, Greenman J, et al. Accumulation of tissue factor in endothelial cells promotes cellular apoptosis through over-activation of Src1 and involves β1-integrin signalling. Apoptosis. 2020;25:29-41 pubmed publisher
He Y, Yuan X, Li Y, Zhong C, Liu Y, Qian H, et al. Loss of Gαq impairs regulatory B-cell function. Arthritis Res Ther. 2018;20:186 pubmed publisher
Zanotto Filho A, Rajamanickam S, Loranc E, Masamsetti V, Gorthi A, Romero J, et al. Sorafenib improves alkylating therapy by blocking induced inflammation, invasion and angiogenesis in breast cancer cells. Cancer Lett. 2018;425:101-115 pubmed publisher
Phoomvuthisarn P, Cross A, Glennon Alty L, Wright H, Edwards S. The CDK inhibitor purvalanol A induces neutrophil apoptosis and increases the turnover rate of Mcl-1: potential role of p38-MAPK in regulation of Mcl-1 turnover. Clin Exp Immunol. 2018;192:171-180 pubmed publisher
Rattanasinchai C, Llewellyn B, Conrad S, Gallo K. MLK3 regulates FRA-1 and MMPs to drive invasion and transendothelial migration in triple-negative breast cancer cells. Oncogenesis. 2017;6:e345 pubmed publisher
Yan J, Hedl M, Abraham C. An inflammatory bowel disease-risk variant in INAVA decreases pattern recognition receptor-induced outcomes. J Clin Invest. 2017;127:2192-2205 pubmed publisher
Huang H, Lin H, Huang M. The lactoferricin B-derived peptide, LfB17-34, induces melanogenesis in B16F10 cells. Int J Mol Med. 2017;39:595-602 pubmed publisher
Zhi L, Yu Y, Li X, Wang D, Wang D. Molecular Control of Innate Immune Response to Pseudomonas aeruginosa Infection by Intestinal let-7 in Caenorhabditis elegans. PLoS Pathog. 2017;13:e1006152 pubmed publisher
Li C, Liu S, Yan R, Han N, WONG K, Li L. CD54-NOTCH1 axis controls tumor initiation and cancer stem cell functions in human prostate cancer. Theranostics. 2017;7:67-80 pubmed publisher
Weijer R, Clavier S, Zaal E, Pijls M, van Kooten R, Vermaas K, et al. Multi-OMIC profiling of survival and metabolic signaling networks in cells subjected to photodynamic therapy. Cell Mol Life Sci. 2017;74:1133-1151 pubmed publisher
Taniguchi T, Maruyama N, Ogata T, Kasahara T, Nakanishi N, Miyagawa K, et al. PTRF/Cavin-1 Deficiency Causes Cardiac Dysfunction Accompanied by Cardiomyocyte Hypertrophy and Cardiac Fibrosis. PLoS ONE. 2016;11:e0162513 pubmed publisher
Geng F, Cheng X, Wu X, Yoo J, Cheng C, Guo J, et al. Inhibition of SOAT1 Suppresses Glioblastoma Growth via Blocking SREBP-1-Mediated Lipogenesis. Clin Cancer Res. 2016;22:5337-5348 pubmed
Jackson J, Singh M, Singh V, Jones L, Davidson G, Ture S, et al. Novel Antiplatelet Activity of Minocycline Involves Inhibition of MLK3-p38 Mitogen Activated Protein Kinase Axis. PLoS ONE. 2016;11:e0157115 pubmed publisher
Tollenaere M, Villumsen B, Blasius M, Nielsen J, Wagner S, Bartek J, et al. p38- and MK2-dependent signalling promotes stress-induced centriolar satellite remodelling via 14-3-3-dependent sequestration of CEP131/AZI1. Nat Commun. 2015;6:10075 pubmed publisher
Joel M, Mughal A, Grieg Z, Murrell W, Palmero S, Mikkelsen B, et al. Targeting PBK/TOPK decreases growth and survival of glioma initiating cells in vitro and attenuates tumor growth in vivo. Mol Cancer. 2015;14:121 pubmed publisher
Taniuchi K, Furihata M, Hanazaki K, Iwasaki S, Tanaka K, Shimizu T, et al. Peroxiredoxin 1 promotes pancreatic cancer cell invasion by modulating p38 MAPK activity. Pancreas. 2015;44:331-40 pubmed publisher
Rodriguez Perez A, Borrajo A, Rodriguez Pallares J, Guerra M, Labandeira Garcia J. Interaction between NADPH-oxidase and Rho-kinase in angiotensin II-induced microglial activation. Glia. 2015;63:466-82 pubmed publisher
Almeida A, Fonseca Pereira D, Arroz Madeira S, Ribeiro H, Labão Almeida C, Veiga Fernandes H. The neurotrophic factor receptor RET regulates IL-10 production by in vitro polarised T helper 2 cells. Eur J Immunol. 2014;44:3605-13 pubmed publisher
Herrero de Dios C, Alonso Monge R, Pla J. The lack of upstream elements of the Cek1 and Hog1 mediated pathways leads to a synthetic lethal phenotype upon osmotic stress in Candida albicans. Fungal Genet Biol. 2014;69:31-42 pubmed publisher
Hammaker D, Boyle D, Topolewski K, Firestein G. Differential regulation of anti-inflammatory genes by p38 MAP kinase and MAP kinase kinase 6. J Inflamm (Lond). 2014;11:14 pubmed publisher
Kosla J, Dvorakova M, Dvorak M, Cermák V. Effective myofibroblast dedifferentiation by concomitant inhibition of TGF-? signaling and perturbation of MAPK signaling. Eur J Cell Biol. 2013;92:363-73 pubmed publisher
Wang C, Weerapana E, Blewett M, Cravatt B. A chemoproteomic platform to quantitatively map targets of lipid-derived electrophiles. Nat Methods. 2014;11:79-85 pubmed publisher
Liu X, Cai T, Zhu H, Cao J, Su Y, Hu Y, et al. Q6, a novel hypoxia-targeted drug, regulates hypoxia-inducible factor signaling via an autophagy-dependent mechanism in hepatocellular carcinoma. Autophagy. 2014;10:111-22 pubmed publisher
George M, Wine R, Lackford B, Kissling G, Akiyama S, Olden K, et al. p38 mitogen-activated protein kinase interacts with vinculin at focal adhesions during fatty acid-stimulated cell adhesion. Biochem Cell Biol. 2013;91:404-18 pubmed publisher
Gillory L, Megison M, Stewart J, Mroczek Musulman E, Nabers H, Waters A, et al. Preclinical evaluation of engineered oncolytic herpes simplex virus for the treatment of neuroblastoma. PLoS ONE. 2013;8:e77753 pubmed publisher
Thomas E, Roman E, Claypool S, Manzoor N, Pla J, Panwar S. Mitochondria influence CDR1 efflux pump activity, Hog1-mediated oxidative stress pathway, iron homeostasis, and ergosterol levels in Candida albicans. Antimicrob Agents Chemother. 2013;57:5580-99 pubmed publisher
Rao S, Liu X, Freedman B, Behrens E. Spleen tyrosine kinase (Syk)-dependent calcium signals mediate efficient CpG-induced exocytosis of tumor necrosis factor ? (TNF?) in innate immune cells. J Biol Chem. 2013;288:12448-58 pubmed publisher
Mamik M, Ghorpade A. Src homology-2 domain-containing protein tyrosine phosphatase (SHP) 2 and p38 regulate the expression of chemokine CXCL8 in human astrocytes. PLoS ONE. 2012;7:e45596 pubmed publisher
Rodríguez Martín S, Kropp K, Wilhelmi V, Lisnic V, Hsieh W, Blanc M, et al. Ablation of the regulatory IE1 protein of murine cytomegalovirus alters in vivo pro-inflammatory TNF-alpha production during acute infection. PLoS Pathog. 2012;8:e1002901 pubmed publisher
Bill M, Nicholas C, Mace T, Etter J, Li C, Schwartz E, et al. Structurally modified curcumin analogs inhibit STAT3 phosphorylation and promote apoptosis of human renal cell carcinoma and melanoma cell lines. PLoS ONE. 2012;7:e40724 pubmed publisher
Gambino Y, Pérez Pérez A, Dueñas J, Calvo J, Sanchez Margalet V, Varone C. Regulation of leptin expression by 17beta-estradiol in human placental cells involves membrane associated estrogen receptor alpha. Biochim Biophys Acta. 2012;1823:900-10 pubmed publisher
Lamb T, Goldsmith C, Bennett L, Finch K, Bell Pedersen D. Direct transcriptional control of a p38 MAPK pathway by the circadian clock in Neurospora crassa. PLoS ONE. 2011;6:e27149 pubmed publisher
Cooper D, Pechkovsky D, Hackett T, Knight D, Granville D. Granzyme K activates protease-activated receptor-1. PLoS ONE. 2011;6:e21484 pubmed publisher
Gehani S, Agrawal Singh S, Dietrich N, Christophersen N, Helin K, Hansen K. Polycomb group protein displacement and gene activation through MSK-dependent H3K27me3S28 phosphorylation. Mol Cell. 2010;39:886-900 pubmed publisher
Marshall A, Barrett O, Cullingford T, Shanmugasundram A, Sugden P, Clerk A. ERK1/2 signaling dominates over RhoA signaling in regulating early changes in RNA expression induced by endothelin-1 in neonatal rat cardiomyocytes. PLoS ONE. 2010;5:e10027 pubmed publisher
McHugh D, Hu S, Rimmerman N, Juknat A, Vogel Z, Walker J, et al. N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor. BMC Neurosci. 2010;11:44 pubmed publisher
Xu P, Derynck R. Direct activation of TACE-mediated ectodomain shedding by p38 MAP kinase regulates EGF receptor-dependent cell proliferation. Mol Cell. 2010;37:551-66 pubmed publisher
Erridge C, Duncan S, Bereswill S, Heimesaat M. The induction of colitis and ileitis in mice is associated with marked increases in intestinal concentrations of stimulants of TLRs 2, 4, and 5. PLoS ONE. 2010;5:e9125 pubmed publisher
Pogozelski A, Geng T, Li P, Yin X, Lira V, Zhang M, et al. p38gamma mitogen-activated protein kinase is a key regulator in skeletal muscle metabolic adaptation in mice. PLoS ONE. 2009;4:e7934 pubmed publisher
Arias C, Walsh D, Harbell J, Wilson A, Mohr I. Activation of host translational control pathways by a viral developmental switch. PLoS Pathog. 2009;5:e1000334 pubmed publisher
Wu M, Desai D, Kakarla S, Katta A, Paturi S, Gutta A, et al. Acetaminophen prevents aging-associated hyperglycemia in aged rats: effect of aging-associated hyperactivation of p38-MAPK and ERK1/2. Diabetes Metab Res Rev. 2009;25:279-86 pubmed publisher
Basak C, Pathak S, Bhattacharyya A, Mandal D, Pathak S, Kundu M. NF-kappaB- and C/EBPbeta-driven interleukin-1beta gene expression and PAK1-mediated caspase-1 activation play essential roles in interleukin-1beta release from Helicobacter pylori lipopolysaccharide-stimulated macrophages. J Biol Chem. 2005;280:4279-88 pubmed
Boncristiano M, Paccani S, Barone S, Ulivieri C, Patrussi L, Ilver D, et al. The Helicobacter pylori vacuolating toxin inhibits T cell activation by two independent mechanisms. J Exp Med. 2003;198:1887-97 pubmed
product information
SKU :
9216S
Product-Name :
Phospho-p38 MAPK (Thr180/Tyr182) (28B10) Mouse mAb
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R, Mk, Sc, (Z)
Applications :
Flow cytometry
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
43
Host :
Mouse
Target :
p38-alpha MAPK (Thr180/Tyr182) phosphate/p38-beta MAPK (Thr188/Tyr190) phosphate/p38-delta MAPK (Thr180/Tyr182) phosphate/p38-gamma MAPK (Thr183/Tyr185) phosphate
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.