product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-p38 MAPK (Thr180/Tyr182) (3D7) Rabbit mAb
catalog :
9215S
quantity :
200 ul
price :
274 USD
clonality :
monoclonal
host :
rabbit
antigen modification :
phosphorylated
clone name :
3D7
reactivity :
human, mouse, rat, dog, cow, pig, rabbit
application :
western blot, immunocytochemistry, flow cytometry, immunohistochemistry - free floating section
citations: 34
Published Application/Species/DilutionReference
  • western blot; mouse; 1:1000; fig 8
Sabogal-Guáqueta A, Osorio E, Cardona-Gomez G. Linalool reverses neuropathological and behavioral impairments in old triple transgenic Alzheimer's mice. Neuropharmacology. 2016;102:111-20 pubmed publisher
  • western blot; human
Kozlova N, Samoylenko A, Drobot L, Kietzmann T. Urokinase is a negative modulator of Egf-dependent proliferation and motility in the two breast cancer cell lines MCF-7 and MDA-MB-231. Mol Carcinog. 2016;55:170-81 pubmed publisher
  • western blot; mouse; 1:1000; fig 2C
Chen L, DeWispelaere A, Dastvan F, Osborne W, Blechner C, Windhorst S, et al. Smooth Muscle-Alpha Actin Inhibits Vascular Smooth Muscle Cell Proliferation and Migration by Inhibiting Rac1 Activity. PLoS ONE. 2016;11:e0155726 pubmed publisher
  • immunocytochemistry; dog; 1:50; fig 4
Wagstaff L, Goschorska M, Kozyrska K, Duclos G, Kucinski I, Chessel A, et al. Mechanical cell competition kills cells via induction of lethal p53 levels. Nat Commun. 2016;7:11373 pubmed publisher
  • western blot; human; 1:1000; fig 5
Ribeiro J, Schorl C, Yano N, Romano N, Kim K, Singh R, et al. HE4 promotes collateral resistance to cisplatin and paclitaxel in ovarian cancer cells. J Ovarian Res. 2016;9:28 pubmed publisher
  • western blot; human; 1:1000; fig 3
Bao H, Liu P, Jiang K, Zhang X, Xie L, Wang Z, et al. Huaier polysaccharide induces apoptosis in hepatocellular carcinoma cells through p38 MAPK. Oncol Lett. 2016;12:1058-1066 pubmed
  • western blot; pig; 1:1000; fig 2A
Springler A, Hessenberger S, Schatzmayr G, Mayer E. Early Activation of MAPK p44/42 Is Partially Involved in DON-Induced Disruption of the Intestinal Barrier Function and Tight Junction Network. Toxins (Basel). 2016;8: pubmed publisher
  • western blot; mouse; fig 3
Møller C, Kjøbsted R, Enriori P, Jensen T, Garcia-Rudaz C, Litwak S, et al. α-MSH Stimulates Glucose Uptake in Mouse Muscle and Phosphorylates Rab-GTPase-Activating Protein TBC1D1 Independently of AMPK. PLoS ONE. 2016;11:e0157027 pubmed publisher
  • western blot; mouse; 1:2000
Dahlhoff M, Schafer M, Muzumdar S, Rose C, Schneider M. ERBB3 is required for tumor promotion in a mouse model of skin carcinogenesis. Mol Oncol. 2015;9:1825-33 pubmed publisher
  • western blot; rat
  • immunocytochemistry; human
Zhang L, Wang H, Ding K, Xu J. FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells. Toxicol Lett. 2015;236:43-59 pubmed publisher
  • western blot; rabbit; 1:1000; fig 3
Varela A, Piperi C, Sigala F, Agrogiannis G, Davos C, Andri M, et al. Elevated expression of mechanosensory polycystins in human carotid atherosclerotic plaques: association with p53 activation and disease severity. Sci Rep. 2015;5:13461 pubmed publisher
  • western blot; human; 1:1000
Zanotto-Filho A, Braganhol E, Klafke K, Figueiró F, Terra S, Paludo F, et al. Autophagy inhibition improves the efficacy of curcumin/temozolomide combination therapy in glioblastomas. Cancer Lett. 2015;358:220-31 pubmed publisher
  • western blot; human; fig 7
Garcia-Cano J, Ambroise G, Pascual-Serra R, Carrión M, Serrano-Oviedo L, Ortega-Muelas M, et al. Exploiting the potential of autophagy in cisplatin therapy: A new strategy to overcome resistance. Oncotarget. 2015;6:15551-65 pubmed
  • western blot; human; fig 1
Dumas A, Lê-Bury G, Marie-Anaïs F, Herit F, Mazzolini J, Guilbert T, et al. The HIV-1 protein Vpr impairs phagosome maturation by controlling microtubule-dependent trafficking. J Cell Biol. 2015;211:359-72 pubmed publisher
  • western blot; mouse; 1:1000
Kim H, Kim I, Dong Y, Lee I, Kim J, Kim J, et al. Melanogenesis-inducing effect of cirsimaritin through increases in microphthalmia-associated transcription factor and tyrosinase expression. Int J Mol Sci. 2015;16:8772-88 pubmed publisher
  • western blot; mouse; 1:500; fig 4
Boncompagni S, Arthurton L, Akujuru E, Pearson T, Steverding D, Protasi F, et al. Membrane glucocorticoid receptors are localised in the extracellular matrix and signal through the MAPK pathway in mammalian skeletal muscle fibres. J Physiol. 2015;593:2679-92 pubmed publisher
  • western blot; rat; 1:1000
Chichger H, Braza J, Duong H, Stark M, Harrington E. Neovascularization in the pulmonary endothelium is regulated by the endosome: Rab4-mediated trafficking and p18-dependent signaling. Am J Physiol Lung Cell Mol Physiol. 2015;309:L700-9 pubmed publisher
  • western blot; human; fig 5
Zhang X, Wang X, Wu T, Li B, Liu T, Wang R, et al. Isoliensinine induces apoptosis in triple-negative human breast cancer cells through ROS generation and p38 MAPK/JNK activation. Sci Rep. 2015;5:12579 pubmed publisher
  • western blot; human
Martin V, Corso S, Comoglio P, Giordano S. Increase of MET gene copy number confers resistance to a monovalent MET antibody and establishes drug dependence. Mol Oncol. 2014;8:1561-74 pubmed publisher
  • western blot; human
Ihunnah C, Wada T, Philips B, Ravuri S, Gibbs R, Kirisci L, et al. Estrogen sulfotransferase/SULT1E1 promotes human adipogenesis. Mol Cell Biol. 2014;34:1682-94 pubmed publisher
  • western blot; pig; 1:500
Zhang S, Ren M, Zeng X, He P, Ma X, Qiao S. Leucine stimulates ASCT2 amino acid transporter expression in porcine jejunal epithelial cell line (IPEC-J2) through PI3K/Akt/mTOR and ERK signaling pathways. Amino Acids. 2014;46:2633-42 pubmed publisher
  • western blot; human
Willemen H, Campos P, Lucas E, Morreale A, Gil-Redondo R, Agut J, et al. A novel p38 MAPK docking-groove-targeted compound is a potent inhibitor of inflammatory hyperalgesia. Biochem J. 2014;459:427-39 pubmed publisher
  • western blot; mouse
Huang S, Lee C, Wang H, Chang Y, Lin C, Chen C, et al. 6-Dehydrogingerdione restrains lipopolysaccharide-induced inflammatory responses in RAW 264.7 macrophages. J Agric Food Chem. 2014;62:9171-9 pubmed publisher
  • western blot; rat
Smith I, Godinez G, Singh B, McCaughey K, Alcantara R, Gururaja T, et al. Inhibition of Janus kinase signaling during controlled mechanical ventilation prevents ventilation-induced diaphragm dysfunction. FASEB J. 2014;28:2790-803 pubmed publisher
  • western blot; mouse; 1:1000
Dou W, Zhang J, Ren G, Ding L, Sun A, Deng C, et al. Mangiferin attenuates the symptoms of dextran sulfate sodium-induced colitis in mice via NF-κB and MAPK signaling inactivation. Int Immunopharmacol. 2014;23:170-8 pubmed publisher
  • western blot; mouse; fig 6
Tang S, Chen T, Yu Z, Zhu X, Yang M, Xie B, et al. RasGRP3 limits Toll-like receptor-triggered inflammatory response in macrophages by activating Rap1 small GTPase. Nat Commun. 2014;5:4657 pubmed publisher
  • western blot; mouse; 1:1000
Yu B, Chang J, Liu Y, Li J, Kevork K, Al-Hezaimi K, et al. Wnt4 signaling prevents skeletal aging and inflammation by inhibiting nuclear factor-κB. Nat Med. 2014;20:1009-17 pubmed publisher
  • immunohistochemistry - free floating section; rat; 1:100
  • western blot; rat; 1:1000
Taylor D, Moser R, Regulier E, Breuillaud L, Dixon M, Beesen A, et al. MAP kinase phosphatase 1 (MKP-1/DUSP1) is neuroprotective in Huntington's disease via additive effects of JNK and p38 inhibition. J Neurosci. 2013;33:2313-25 pubmed publisher
Kollar P, Bárta T, Keltosova S, Trnová P, Müller Závalová V, Smejkal K, et al. Flavonoid 4'-O-Methylkuwanon E from Morus alba Induces the Differentiation of THP-1 Human Leukemia Cells. Evid Based Complement Alternat Med. 2015;2015:251895 pubmed publisher
Ponichtera H, Shainheit M, Liu B, Raychowdhury R, Larkin B, Russo J, et al. CD209a expression on dendritic cells is critical for the development of pathogenic Th17 cell responses in murine schistosomiasis. J Immunol. 2014;192:4655-65 pubmed publisher
Wang Q, Chu C, Qian L, Chen S, Wilson B, Oyarzabal E, et al. Substance P exacerbates dopaminergic neurodegeneration through neurokinin-1 receptor-independent activation of microglial NADPH oxidase. J Neurosci. 2014;34:12490-503 pubmed publisher
Yang P, An H, Liu X, Wen M, Zheng Y, Rui Y, et al. The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway. Nat Immunol. 2010;11:487-94 pubmed publisher
Owaki T, Asakawa M, Fukai F, Mizuguchi J, Yoshimoto T. IL-27 induces Th1 differentiation via p38 MAPK/T-bet- and intercellular adhesion molecule-1/LFA-1/ERK1/2-dependent pathways. J Immunol. 2006;177:7579-87 pubmed
Hayakawa E, Yoshimoto T, Sekizawa N, Sugiyama T, Hirata Y. Overexpression of receptor for advanced glycation end products induces monocyte chemoattractant protein-1 expression in rat vascular smooth muscle cell line. J Atheroscler Thromb. 2012;19:13-22 pubmed
product information
SKU :
9215S
Product-Name :
Phospho-p38 MAPK (Thr180/Tyr182) (3D7) Rabbit mAb
Size :
200 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R, Mk, Dm, Pg, Sc, (Hm, B)
Applications :
Flow cytometry
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
43
Host :
Rabbit
Target :
p38-alpha MAPK (Thr180/Tyr182) phosphate/p38-beta MAPK (Thr188/Tyr190) phosphate/p38-delta MAPK (Thr180/Tyr182) phosphate/p38-gamma MAPK (Thr183/Tyr185) phosphate
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.