Phospho-p38 MAPK (Thr180/Tyr182) (3D7) Rabbit mAb | Cell Signaling Technology 9215 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Phospho-p38 MAPK (Thr180/Tyr182) (3D7) Rabbit mAb

catalog :

9215

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

clone name :

3D7

reactivity :

human, mouse, rat, dogs, bovine, pigs , zebrafish , fruit fly , domestic rabbit

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - free floating section

more info or order :

Cell Signaling Technology product webpage

citations: 122

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:1000; fig 3f	Hoste E, Lecomte K, Annusver K, Vandamme N, Roels J, Maschalidi S, et al. OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity. Nat Commun. 2021;12:5913 pubmed publisher
western blot; mouse; loading ...; fig 7a	Rajendran R, Rajendran V, Giraldo Velasquez M, Megalofonou F, Gurski F, Stadelmann C, et al. Oligodendrocyte-Specific Deletion of FGFR1 Reduces Cerebellar Inflammation and Neurodegeneration in MOG35-55-Induced EAE. Int J Mol Sci. 2021;22: pubmed publisher
western blot; mouse; loading ...; fig 5a	Yang S, Qu Y, Chen J, Chen S, Sun L, Zhou Y, et al. Bee Pollen Polysaccharide From Rosa rugosa Thunb. (Rosaceae) Promotes Pancreatic β-Cell Proliferation and Insulin Secretion. Front Pharmacol. 2021;12:688073 pubmed publisher
western blot; mouse; loading ...; fig 7e	Kim C, Park S, Lee S, Kim Y, Jang S, Woo S, et al. NSrp70 is a lymphocyte-essential splicing factor that controls thymocyte development. Nucleic Acids Res. 2021;49:5760-5778 pubmed publisher
western blot; human; 1:1000; loading ...; fig 6d	Low H, Wong Z, Wu B, Kong L, Png C, Cho Y, et al. DUSP16 promotes cancer chemoresistance through regulation of mitochondria-mediated cell death. Nat Commun. 2021;12:2284 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 6c	Kushioka J, Kaito T, Okada R, Ishiguro H, Bal Z, Kodama J, et al. A novel negative regulatory mechanism of Smurf2 in BMP/Smad signaling in bone. Bone Res. 2020;8:41 pubmed publisher
immunohistochemistry; fruit fly ; 1:100; loading ...; fig 5f western blot; fruit fly ; 1:1000; fig s5b	Seong K, Ly N, Katou Y, Yokota N, Nakato R, Murakami S, et al. Paternal restraint stress affects offspring metabolism via ATF-2 dependent mechanisms in Drosophila melanogaster germ cells. Commun Biol. 2020;3:208 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 1a	Gee M, Son S, Jeon S, Do J, Kim N, Ju Y, et al. A selective p38α/β MAPK inhibitor alleviates neuropathology and cognitive impairment, and modulates microglia function in 5XFAD mouse. Alzheimers Res Ther. 2020;12:45 pubmed publisher
western blot; human; 1:500; loading ...; fig 2g, 2s1a, 2s3d	Bogucka K, Pompaiah M, Marini F, Binder H, Harms G, Kaulich M, et al. ERK3/MAPK6 controls IL-8 production and chemotaxis. elife. 2020;9: pubmed publisher
western blot; human; loading ...; fig 6b	Xu F, Liu Z, Liu R, Lu C, Wang L, Mao W, et al. Epigenetic induction of tumor stemness via the lipopolysaccharide-TET3-HOXB2 signaling axis in esophageal squamous cell carcinoma. Cell Commun Signal. 2020;18:17 pubmed publisher
western blot; human; 1:1000; loading ...; fig 3b	Zewinger S, Reiser J, Jankowski V, Alansary D, Hahm E, Triem S, et al. Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation. Nat Immunol. 2020;21:30-41 pubmed publisher
immunocytochemistry; human; 1:100; loading ...; fig 2a	Bailey K, Moreno E, Haj F, Simon S, Passerini A. Mechanoregulation of p38 activity enhances endoplasmic reticulum stress-mediated inflammation by arterial endothelium. FASEB J. 2019;33:12888-12899 pubmed publisher
western blot; human; loading ...; fig 4a	Gu C, Wang L, Zurawski S, Oh S. Signaling Cascade through DC-ASGPR Induces Transcriptionally Active CREB for IL-10 Induction and Immune Regulation. J Immunol. 2019;: pubmed publisher
western blot; human; loading ...; fig 4a	Sabol R, Bowles A, Côté A, Wise R, O Donnell B, Matossian M, et al. Leptin produced by obesity-altered adipose stem cells promotes metastasis but not tumorigenesis of triple-negative breast cancer in orthotopic xenograft and patient-derived xenograft models. Breast Cancer Res. 2019;21:67 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 4d	Udden S, Kwak Y, Godfrey V, Khan M, Khan S, Loof N, et al. NLRP12 suppresses hepatocellular carcinoma via downregulation of cJun N-terminal kinase activation in the hepatocyte. elife. 2019;8: pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 5b	Araiz C, Yan A, Bettedi L, Samuelson I, Virtue S, McGavigan A, et al. Enhanced β-adrenergic signalling underlies an age-dependent beneficial metabolic effect of PI3K p110α inactivation in adipose tissue. Nat Commun. 2019;10:1546 pubmed publisher
western blot; human; loading ...; fig 6f western blot; mouse; loading ...; fig 6a	Mentrup T, Theodorou K, Cabrera Cabrera F, Helbig A, Happ K, Gijbels M, et al. Atherogenic LOX-1 signaling is controlled by SPPL2-mediated intramembrane proteolysis. J Exp Med. 2019;: pubmed publisher
western blot; human; loading ...; fig s2	Zhang Z, Chen J, Huang W, Ning D, Liu Q, Wang C, et al. FAM134B induces tumorigenesis and epithelial-to-mesenchymal transition via Akt signaling in hepatocellular carcinoma. Mol Oncol. 2019;13:792-810 pubmed publisher
western blot; mouse; loading ...; fig 4b	Hou M, Wang W, Hu F, Zhang Y, Yang D, Liu Q. Phosphothreonine Lyase Promotes p65 Degradation in a Mitogen-Activated Protein Kinase/Mitogen- and Stress-Activated Protein Kinase 1-Dependent Manner. Infect Immun. 2019;87: pubmed publisher
western blot; human; fig 7c	Fauster A, Rebsamen M, Willmann K, César Razquin A, Girardi E, Bigenzahn J, et al. Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking. Cell Death Differ. 2019;26:1138-1155 pubmed publisher
western blot; mouse; loading ...; fig 2i	Jun H, Yu H, Gong J, Jiang J, Qiao X, Perkey E, et al. An immune-beige adipocyte communication via nicotinic acetylcholine receptor signaling. Nat Med. 2018;24:814-822 pubmed publisher
western blot; human; loading ...; fig 6f	Han Y, Liu Q, Hou J, Gu Y, Zhang Y, Chen Z, et al. Tumor-Induced Generation of Splenic Erythroblast-like Ter-Cells Promotes Tumor Progression. Cell. 2018;173:634-648.e12 pubmed publisher
western blot; mouse; loading ...; fig 1f	Magilnick N, Reyes E, Wang W, Vonderfecht S, Gohda J, Inoue J, et al. miR-146a-Traf6 regulatory axis controls autoimmunity and myelopoiesis, but is dispensable for hematopoietic stem cell homeostasis and tumor suppression. Proc Natl Acad Sci U S A. 2017;114:E7140-E7149 pubmed publisher
western blot; mouse; fig s5b	Bae S, Lee M, Mun S, Giannopoulou E, Yong Gonzalez V, Cross J, et al. MYC-dependent oxidative metabolism regulates osteoclastogenesis via nuclear receptor ERR?. J Clin Invest. 2017;127:2555-2568 pubmed publisher
western blot; mouse; 1:200; loading ...; fig 3d	Nishimura S, Mishra Gorur K, Park J, Surovtseva Y, Sebti S, Levchenko A, et al. Combined HMG-COA reductase and prenylation inhibition in treatment of CCM. Proc Natl Acad Sci U S A. 2017;114:5503-5508 pubmed publisher
western blot; human; loading ...; fig s7f western blot; mouse; fig s7e	Yang Y, Liu B, Xu J, Wang J, Wu J, Shi C, et al. Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency. Cell. 2017;169:243-257.e25 pubmed publisher
western blot; mouse; 1:3000; loading ...; fig 3a	Song Y, Lai L, Chong Z, He J, Zhang Y, Xue Y, et al. E3 ligase FBXW7 is critical for RIG-I stabilization during antiviral responses. Nat Commun. 2017;8:14654 pubmed publisher
western blot; human; loading ...; fig 1g	Li L, Baxter S, Gu N, Ji M, Zhan X. Missing-in-metastasis protein downregulates CXCR4 by promoting ubiquitylation and interaction with small Rab GTPases. J Cell Sci. 2017;130:1475-1485 pubmed publisher
western blot; mouse; loading ...; fig EV3d western blot; human; loading ...; fig 7a	Lafont E, Kantari Mimoun C, Dráber P, De Miguel D, Hartwig T, Reichert M, et al. The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death. EMBO J. 2017;36:1147-1166 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig S17A	Li C, Bi Y, Li Y, Yang H, Yu Q, Wang J, et al. Dendritic cell MST1 inhibits Th17 differentiation. Nat Commun. 2017;8:14275 pubmed publisher
western blot; human; 1:2000; loading ...; fig 5E	Pyle C, Akhter S, Bao S, Dodd C, Schlesinger L, Knoell D. Zinc Modulates Endotoxin-Induced Human Macrophage Inflammation through ZIP8 Induction and C/EBP? Inhibition. PLoS ONE. 2017;12:e0169531 pubmed publisher
western blot; human; 1:1000; loading ...; fig 5a	Marmisolle I, MartÃnez J, Liu J, Mastrogiovanni M, Fergusson M, Rovira I, et al. Reciprocal regulation of acetyl-CoA carboxylase 1 and senescence in human fibroblasts involves oxidant mediated p38 MAPK activation. Arch Biochem Biophys. 2017;613:12-22 pubmed publisher
western blot; human; loading ...; fig 2a	Yue G, Xie S, Lee J, Kwok H, Gao S, Nian Y, et al. New potential beneficial effects of actein, a triterpene glycoside isolated from Cimicifuga species, in breast cancer treatment. Sci Rep. 2016;6:35263 pubmed publisher
western blot; pigs ; 1:1000; fig 2A	Springler A, Hessenberger S, Schatzmayr G, Mayer E. Early Activation of MAPK p44/42 Is Partially Involved in DON-Induced Disruption of the Intestinal Barrier Function and Tight Junction Network. Toxins (Basel). 2016;8: pubmed publisher
immunohistochemistry; zebrafish ; 1:500; loading ...; fig 5a	Kasica N, Podlasz P, Sundvik M, Tamas A, Reglodi D, Kaleczyc J. Protective Effects of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Against Oxidative Stress in Zebrafish Hair Cells. Neurotox Res. 2016;30:633-647 pubmed
flow cytometry; human; loading ...; fig 5b	Hedl M, Yan J, Abraham C. IRF5 and IRF5 Disease-Risk Variants Increase Glycolysis and Human M1 Macrophage Polarization by Regulating Proximal Signaling and Akt2 Activation. Cell Rep. 2016;16:2442-55 pubmed publisher
western blot; mouse; fig 3	Møller C, Kjøbsted R, Enriori P, Jensen T, Garcia Rudaz C, Litwak S, et al. ?-MSH Stimulates Glucose Uptake in Mouse Muscle and Phosphorylates Rab-GTPase-Activating Protein TBC1D1 Independently of AMPK. PLoS ONE. 2016;11:e0157027 pubmed publisher
western blot; human; 1:1000; fig 3	Bao H, Liu P, Jiang K, Zhang X, Xie L, Wang Z, et al. Huaier polysaccharide induces apoptosis in hepatocellular carcinoma cells through p38 MAPK. Oncol Lett. 2016;12:1058-1066 pubmed
western blot; mouse; 1:1000; loading ...; fig s3e	Xiang N, Liu J, Liao Y, Huang Y, Wu Z, Bai Z, et al. Abrogating ClC-3 Inhibits LPS-induced Inflammation via Blocking the TLR4/NF-ÎºB Pathway. Sci Rep. 2016;6:27583 pubmed publisher
western blot; human; 1:1000; fig 5	Ribeiro J, Schorl C, Yano N, Romano N, Kim K, Singh R, et al. HE4 promotes collateral resistance to cisplatin and paclitaxel in ovarian cancer cells. J Ovarian Res. 2016;9:28 pubmed publisher
western blot; mouse; 1:1000; fig 2C	Chen L, DeWispelaere A, Dastvan F, Osborne W, Blechner C, Windhorst S, et al. Smooth Muscle-Alpha Actin Inhibits Vascular Smooth Muscle Cell Proliferation and Migration by Inhibiting Rac1 Activity. PLoS ONE. 2016;11:e0155726 pubmed publisher
western blot; human; fig 9e western blot; bovine; loading ...; fig 9f	Ishizuka S, Askew E, Ishizuka N, Knudson C, Knudson W. 4-Methylumbelliferone Diminishes Catabolically Activated Articular Chondrocytes and Cartilage Explants via a Mechanism Independent of Hyaluronan Inhibition. J Biol Chem. 2016;291:12087-104 pubmed publisher
western blot; human; loading ...; fig 1c	Afonina I, Van Nuffel E, Baudelet G, Driege Y, Kreike M, Staal J, et al. The paracaspase MALT1 mediates CARD14-induced signaling in keratinocytes. EMBO Rep. 2016;17:914-27 pubmed publisher
immunocytochemistry; dogs; 1:50; fig 4	Wagstaff L, Goschorska M, Kozyrska K, Duclos G, Kucinski I, Chessel A, et al. Mechanical cell competition kills cells via induction of lethal p53 levels. Nat Commun. 2016;7:11373 pubmed publisher
western blot; human; fig 4	Chusri P, Kumthip K, Hong J, Zhu C, Duan X, Jilg N, et al. HCV induces transforming growth factor Î²1 through activation of endoplasmic reticulum stress and the unfolded protein response. Sci Rep. 2016;6:22487 pubmed publisher
western blot; mouse; fig 1	Thornton T, Delgado P, Chen L, Salas B, Krementsov D, Fernández M, et al. Inactivation of nuclear GSK3β by Ser(389) phosphorylation promotes lymphocyte fitness during DNA double-strand break response. Nat Commun. 2016;7:10553 pubmed publisher
western blot; mouse; 1:1000; fig s7	Franco Villanueva A, Wandosell F, AntÃ³n I. Neuritic complexity of hippocampal neurons depends on WIP-mediated mTORC1 and Abl family kinases activities. Brain Behav. 2015;5:e00359 pubmed publisher
western blot; mouse; 1:1000; fig 8	Sabogal GuÃ¡queta A, Osorio E, Cardona GÃ³mez G. Linalool reverses neuropathological and behavioral impairments in old triple transgenic Alzheimer's mice. Neuropharmacology. 2016;102:111-20 pubmed publisher
western blot; human; fig 1	Dumas A, LÃª Bury G, Marie AnaÃ¯s F, Herit F, Mazzolini J, Guilbert T, et al. The HIV-1 protein Vpr impairs phagosome maturation by controlling microtubule-dependent trafficking. J Cell Biol. 2015;211:359-72 pubmed publisher
western blot; domestic rabbit; 1:1000; fig 3	Varela A, Piperi C, Sigala F, Agrogiannis G, Davos C, Andri M, et al. Elevated expression of mechanosensory polycystins in human carotid atherosclerotic plaques: association with p53 activation and disease severity. Sci Rep. 2015;5:13461 pubmed publisher
western blot; rat; 1:1000	Chichger H, Braza J, Duong H, Stark M, Harrington E. Neovascularization in the pulmonary endothelium is regulated by the endosome: Rab4-mediated trafficking and p18-dependent signaling. Am J Physiol Lung Cell Mol Physiol. 2015;309:L700-9 pubmed publisher
western blot; human; fig 5	Zhang X, Wang X, Wu T, Li B, Liu T, Wang R, et al. Isoliensinine induces apoptosis in triple-negative human breast cancer cells through ROS generation and p38 MAPK/JNK activation. Sci Rep. 2015;5:12579 pubmed publisher
western blot; mouse; 1:2000	Dahlhoff M, SchÃ¤fer M, Muzumdar S, Rose C, Schneider M. ERBB3 is required for tumor promotion in a mouse model of skin carcinogenesis. Mol Oncol. 2015;9:1825-33 pubmed publisher
western blot; human; fig 2	Su X, Yu Y, Zhong Y, Giannopoulou E, Hu X, Liu H, et al. Interferon-Î³ regulates cellular metabolism and mRNA translation to potentiate macrophage activation. Nat Immunol. 2015;16:838-849 pubmed publisher
western blot; rat; 1:1000; fig 6	Wu P, Yen J, Kou M, Wu M. Luteolin and Apigenin Attenuate 4-Hydroxy-2-Nonenal-Mediated Cell Death through Modulation of UPR, Nrf2-ARE and MAPK Pathways in PC12 Cells. PLoS ONE. 2015;10:e0130599 pubmed publisher
western blot; human; fig 7	GarcÃa Cano J, Ambroise G, Pascual Serra R, CarriÃ³n M, Serrano Oviedo L, Ortega Muelas M, et al. Exploiting the potential of autophagy in cisplatin therapy: A new strategy to overcome resistance. Oncotarget. 2015;6:15551-65 pubmed
western blot; rat immunocytochemistry; human	Zhang L, Wang H, Ding K, Xu J. FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells. Toxicol Lett. 2015;236:43-59 pubmed publisher
western blot; mouse; 1:1000	Kim H, Kim I, Dong Y, Lee I, Kim J, Kim J, et al. Melanogenesis-inducing effect of cirsimaritin through increases in microphthalmia-associated transcription factor and tyrosinase expression. Int J Mol Sci. 2015;16:8772-88 pubmed publisher
western blot; mouse; 1:500; fig 4	Boncompagni S, Arthurton L, Akujuru E, Pearson T, Steverding D, Protasi F, et al. Membrane glucocorticoid receptors are localised in the extracellular matrix and signal through the MAPK pathway in mammalian skeletal muscle fibres. J Physiol. 2015;593:2679-92 pubmed publisher
western blot; mouse; 1:1000; fig 2	Ko R, Park J, Ha H, Choi Y, Lee S. Glycogen synthase kinase 3Î² ubiquitination by TRAF6 regulates TLR3-mediated pro-inflammatory cytokine production. Nat Commun. 2015;6:6765 pubmed publisher
western blot; human; fig 5	Kollar P, BÃ¡rta T, KeltoÅ¡ovÃ¡ S, TrnovÃ¡ P, MÃ¼ller ZÃ¡valovÃ¡ V, Å mejkal K, et al. Flavonoid 4'-O-Methylkuwanon E from Morus alba Induces the Differentiation of THP-1 Human Leukemia Cells. Evid Based Complement Alternat Med. 2015;2015:251895 pubmed publisher
western blot; human	Kozlova N, Samoylenko A, Drobot L, Kietzmann T. Urokinase is a negative modulator of Egf-dependent proliferation and motility in the two breast cancer cell lines MCF-7 and MDA-MB-231. Mol Carcinog. 2016;55:170-81 pubmed publisher
western blot; human; 1:1000	Zanotto Filho A, Braganhol E, Klafke K, FigueirÃ³ F, Terra S, Paludo F, et al. Autophagy inhibition improves the efficacy of curcumin/temozolomide combination therapy in glioblastomas. Cancer Lett. 2015;358:220-31 pubmed publisher
western blot; human; loading ...; fig 3a	Li Y, Kim B, Cho S, Bang M, Kim S, Park D. 6,7-di-O-acetylsinococuline (FK-3000) induces G2/M phase arrest in breast carcinomas through p38 MAPK phosphorylation and CDC25B dephosphorylation. Int J Oncol. 2015;46:578-86 pubmed publisher
western blot; mouse; 1:1000	Dou W, Zhang J, Ren G, Ding L, Sun A, Deng C, et al. Mangiferin attenuates the symptoms of dextran sulfate sodium-induced colitis in mice via NF-ÎºB and MAPK signaling inactivation. Int Immunopharmacol. 2014;23:170-8 pubmed publisher
western blot; mouse	Huang S, Lee C, Wang H, Chang Y, Lin C, Chen C, et al. 6-Dehydrogingerdione restrains lipopolysaccharide-induced inflammatory responses in RAW 264.7 macrophages. J Agric Food Chem. 2014;62:9171-9 pubmed publisher
western blot; mouse; fig 6	Tang S, Chen T, Yu Z, Zhu X, Yang M, Xie B, et al. RasGRP3 limits Toll-like receptor-triggered inflammatory response in macrophages by activating Rap1 small GTPase. Nat Commun. 2014;5:4657 pubmed publisher
western blot; mouse; 1:1000	Yu B, Chang J, Liu Y, Li J, Kevork K, Al Hezaimi K, et al. Wnt4 signaling prevents skeletal aging and inflammation by inhibiting nuclear factor-?B. Nat Med. 2014;20:1009-17 pubmed publisher
western blot; pigs ; 1:500	Zhang S, Ren M, Zeng X, He P, Ma X, Qiao S. Leucine stimulates ASCT2 amino acid transporter expression in porcine jejunal epithelial cell line (IPEC-J2) through PI3K/Akt/mTOR and ERK signaling pathways. Amino Acids. 2014;46:2633-42 pubmed publisher
western blot; human	Martin V, Corso S, Comoglio P, Giordano S. Increase of MET gene copy number confers resistance to a monovalent MET antibody and establishes drug dependence. Mol Oncol. 2014;8:1561-74 pubmed publisher
western blot; rat	Smith I, Godinez G, Singh B, McCaughey K, Alcantara R, Gururaja T, et al. Inhibition of Janus kinase signaling during controlled mechanical ventilation prevents ventilation-induced diaphragm dysfunction. FASEB J. 2014;28:2790-803 pubmed publisher
western blot; human	Ihunnah C, Wada T, Philips B, Ravuri S, Gibbs R, Kirisci L, et al. Estrogen sulfotransferase/SULT1E1 promotes human adipogenesis. Mol Cell Biol. 2014;34:1682-94 pubmed publisher
western blot; human; fig 5	Willemen H, Campos P, Lucas E, Morreale A, Gil Redondo R, Agut J, et al. A novel p38 MAPK docking-groove-targeted compound is a potent inhibitor of inflammatory hyperalgesia. Biochem J. 2014;459:427-39 pubmed publisher
immunohistochemistry - free floating section; rat; 1:100 western blot; rat; 1:1000	Taylor D, Moser R, Regulier E, Breuillaud L, Dixon M, Beesen A, et al. MAP kinase phosphatase 1 (MKP-1/DUSP1) is neuroprotective in Huntington's disease via additive effects of JNK and p38 inhibition. J Neurosci. 2013;33:2313-25 pubmed publisher
western blot; human; fig 7d	Joaquin M, Gubern A, Gonzalez Nunez D, Josué Ruiz E, Ferreiro I, de Nadal E, et al. The p57 CDKi integrates stress signals into cell-cycle progression to promote cell survival upon stress. EMBO J. 2012;31:2952-64 pubmed publisher
	Cheng X, Peuckert C, Wolfl S. Essential role of mitochondrial Stat3 in p38MAPK mediated apoptosis under oxidative stress. Sci Rep. 2017;7:15388 pubmed publisher
	Yan J, Hedl M, Abraham C. An inflammatory bowel disease-risk variant in INAVA decreases pattern recognition receptor-induced outcomes. J Clin Invest. 2017;127:2192-2205 pubmed publisher
	Sama R, Fallini C, Gatto R, McKeon J, Song Y, Rotunno M, et al. ALS-linked FUS exerts a gain of toxic function involving aberrant p38 MAPK activation. Sci Rep. 2017;7:115 pubmed publisher
	Houslay K, Christian F, MacLeod R, Adams D, Houslay M, Baillie G. Identification of a multifunctional docking site on the catalytic unit of phosphodiesterase-4 (PDE4) that is utilised by multiple interaction partners. Biochem J. 2017;474:597-609 pubmed publisher
	Tu D, Chang W, Jan M, Tu C, Lu Y, Tai C. Promotion of metastasis of thyroid cancer cells via NRP-2-mediated induction. Oncol Lett. 2016;12:4224-4230 pubmed
	Berth S, Mesnard Hoaglin N, Wang B, Kim H, Song Y, Sapar M, et al. HIV Glycoprotein Gp120 Impairs Fast Axonal Transport by Activating Tak1 Signaling Pathways. ASN Neuro. 2016;8: pubmed
	Raguz Nakic Z, Seisenbacher G, Posas F, Sauer U. Untargeted metabolomics unravels functionalities of phosphorylation sites in Saccharomyces cerevisiae. BMC Syst Biol. 2016;10:104 pubmed
	Wu X, Cao D, Zhang X, Jiang B, Zhao L, Qian B, et al. CXCL13/CXCR5 enhances sodium channel Nav1.8 current density via p38 MAP kinase in primary sensory neurons following inflammatory pain. Sci Rep. 2016;6:34836 pubmed publisher
	Ding H, Wu P, Wu M. Cleome rutidosperma and Euphorbia thymifolia Suppress Inflammatory Response via Upregulation of Phase II Enzymes and Modulation of NF-?B and JNK Activation in LPS-Stimulated BV2 Microglia. Int J Mol Sci. 2016;17: pubmed publisher
	Chatterjee B, Wolff D, Jothi M, Mal M, Mal A. p38? MAPK disables KMT1A-mediated repression of myogenic differentiation program. Skelet Muscle. 2016;6:28 pubmed publisher
	Konishi H, Fujiya M, Tanaka H, Ueno N, Moriichi K, Sasajima J, et al. Probiotic-derived ferrichrome inhibits colon cancer progression via JNK-mediated apoptosis. Nat Commun. 2016;7:12365 pubmed publisher
	Li M, Wang J, Fang Y, Gong S, Li M, Wu M, et al. microRNA-146a promotes mycobacterial survival in macrophages through suppressing nitric oxide production. Sci Rep. 2016;6:23351 pubmed publisher
	Espe M, Holen E, He J, Provan F, Chen L, Øysæd K, et al. Hydrolyzed fish proteins reduced activation of caspase-3 in H2O2 induced oxidative stressed liver cells isolated from Atlantic salmon (Salmo salar). Springerplus. 2015;4:658 pubmed publisher
	Kratochvill F, Gratz N, Qualls J, Van De Velde L, Chi H, Kovarik P, et al. Tristetraprolin Limits Inflammatory Cytokine Production in Tumor-Associated Macrophages in an mRNA Decay-Independent Manner. Cancer Res. 2015;75:3054-64 pubmed publisher
	Dexter J, Xu P, Gunawardena J, McClean M. Robust network structure of the Sln1-Ypd1-Ssk1 three-component phospho-relay prevents unintended activation of the HOG MAPK pathway in Saccharomyces cerevisiae. BMC Syst Biol. 2015;9:17 pubmed publisher
	Lewis K, Wason E, Edrey Y, Kristan D, Nevo E, Buffenstein R. Regulation of Nrf2 signaling and longevity in naturally long-lived rodents. Proc Natl Acad Sci U S A. 2015;112:3722-7 pubmed publisher
	Park Min K, Lim E, Lee M, Park S, Giannopoulou E, Yarilina A, et al. Inhibition of osteoclastogenesis and inflammatory bone resorption by targeting BET proteins and epigenetic regulation. Nat Commun. 2014;5:5418 pubmed publisher
	Wang Q, Chu C, Qian L, Chen S, Wilson B, Oyarzabal E, et al. Substance P exacerbates dopaminergic neurodegeneration through neurokinin-1 receptor-independent activation of microglial NADPH oxidase. J Neurosci. 2014;34:12490-503 pubmed publisher
	Wang L, Chiou S, Shen Y, Yen F, Ding H, Wu M. Anti-inflammatory effect and mechanism of the green fruit extract of Solanum integrifolium Poir. Biomed Res Int. 2014;2014:953873 pubmed publisher
	Dang S, Xu H, Xu C, Cai W, Li Q, Cheng Y, et al. Autophagy regulates the therapeutic potential of mesenchymal stem cells in experimental autoimmune encephalomyelitis. Autophagy. 2014;10:1301-15 pubmed publisher
	Chi W, Dao D, Lau T, Henriksbo B, Cavallari J, Foley K, et al. Bacterial peptidoglycan stimulates adipocyte lipolysis via NOD1. PLoS ONE. 2014;9:e97675 pubmed publisher
	Bartell S, Kim H, Ambrogini E, Han L, Iyer S, Serra Ucer S, et al. FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H2O2 accumulation. Nat Commun. 2014;5:3773 pubmed publisher
	Ponichtera H, Shainheit M, Liu B, Raychowdhury R, Larkin B, Russo J, et al. CD209a expression on dendritic cells is critical for the development of pathogenic Th17 cell responses in murine schistosomiasis. J Immunol. 2014;192:4655-65 pubmed publisher
	Ruiz E, Oeztuerk Winder F, Ventura J. A paracrine network regulates the cross-talk between human lung stem cells and the stroma. Nat Commun. 2014;5:3175 pubmed publisher
	Park Y, Yoon S, Suh H, Kim D, Park J, Jung H, et al. TXNIP deficiency exacerbates endotoxic shock via the induction of excessive nitric oxide synthesis. PLoS Pathog. 2013;9:e1003646 pubmed publisher
	Morfini G, Bosco D, Brown H, Gatto R, Kaminska A, Song Y, et al. Inhibition of fast axonal transport by pathogenic SOD1 involves activation of p38 MAP kinase. PLoS ONE. 2013;8:e65235 pubmed publisher
	Abadi A, Crane J, Ogborn D, Hettinga B, Akhtar M, Stokl A, et al. Supplementation with ?-lipoic acid, CoQ10, and vitamin E augments running performance and mitochondrial function in female mice. PLoS ONE. 2013;8:e60722 pubmed publisher
	Monick M, Baltrusaitis J, Powers L, Borcherding J, Caraballo J, Mudunkotuwa I, et al. Effects of Eyjafjallajökull volcanic ash on innate immune system responses and bacterial growth in vitro. Environ Health Perspect. 2013;121:691-8 pubmed publisher
	Garcia Garcia F, Mullol J, Perez Gonzalez M, Pujols L, Alobid I, Roca Ferrer J, et al. Signal transduction pathways (MAPKs, NF-?B, and C/EBP) regulating COX-2 expression in nasal fibroblasts from asthma patients with aspirin intolerance. PLoS ONE. 2012;7:e51281 pubmed publisher
	Humphries L, Shaffer M, Sacirbegovic F, Tomassian T, McMahon K, Humbert P, et al. Characterization of in vivo Dlg1 deletion on T cell development and function. PLoS ONE. 2012;7:e45276 pubmed publisher
	Moriyama M, Moriyama H, Ueda A, Nishibata Y, Okura H, Ichinose A, et al. Human adipose tissue-derived multilineage progenitor cells exposed to oxidative stress induce neurite outgrowth in PC12 cells through p38 MAPK signaling. BMC Cell Biol. 2012;13:21 pubmed publisher
	Ma Y, Zhang X, Bao H, Mi S, Cai W, Yan H, et al. Toll-like receptor (TLR) 2 and TLR4 differentially regulate doxorubicin induced cardiomyopathy in mice. PLoS ONE. 2012;7:e40763 pubmed publisher
	Daroqui M, Vazquez P, Bal de Kier Joffe E, Bakin A, Puricelli L. TGF-? autocrine pathway and MAPK signaling promote cell invasiveness and in vivo mammary adenocarcinoma tumor progression. Oncol Rep. 2012;28:567-75 pubmed publisher
	Liu X, Ma B, Malik A, Tang H, Yang T, Sun B, et al. Bidirectional regulation of neutrophil migration by mitogen-activated protein kinases. Nat Immunol. 2012;13:457-64 pubmed publisher
	Kummer S, Jeruschke S, Wegerich L, Peters A, Lehmann P, Seibt A, et al. Estrogen receptor alpha expression in podocytes mediates protection against apoptosis in-vitro and in-vivo. PLoS ONE. 2011;6:e27457 pubmed publisher
	Hayakawa E, Yoshimoto T, Sekizawa N, Sugiyama T, Hirata Y. Overexpression of receptor for advanced glycation end products induces monocyte chemoattractant protein-1 expression in rat vascular smooth muscle cell line. J Atheroscler Thromb. 2012;19:13-22 pubmed
	Li C, Fan S, Owonikoko T, Khuri F, Sun S, Li R. Oncogenic role of EAPII in lung cancer development and its activation of the MAPK-ERK pathway. Oncogene. 2011;30:3802-12 pubmed publisher
	Bulua A, Simon A, Maddipati R, Pelletier M, Park H, Kim K, et al. Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS). J Exp Med. 2011;208:519-33 pubmed publisher
	Hsieh C, Kuro O M, Rosenblatt K, Brobey R, Papaconstantinou J. The ASK1-Signalosome regulates p38 MAPK activity in response to levels of endogenous oxidative stress in the Klotho mouse models of aging. Aging (Albany NY). 2010;2:597-611 pubmed
	MacNeil L, Melov S, Hubbard A, Baker S, Tarnopolsky M. Eccentric exercise activates novel transcriptional regulation of hypertrophic signaling pathways not affected by hormone changes. PLoS ONE. 2010;5:e10695 pubmed publisher
	Yang P, An H, Liu X, Wen M, Zheng Y, Rui Y, et al. The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway. Nat Immunol. 2010;11:487-94 pubmed publisher
	Leitao B, Jones M, Fusi L, Higham J, Lee Y, Takano M, et al. Silencing of the JNK pathway maintains progesterone receptor activity in decidualizing human endometrial stromal cells exposed to oxidative stress signals. FASEB J. 2010;24:1541-51 pubmed publisher
	Sun F, Chen Q, Yang S, Pan Q, Ma J, Wan Y, et al. Remodeling of chromatin structure within the promoter is important for bmp-2-induced fgfr3 expression. Nucleic Acids Res. 2009;37:3897-911 pubmed publisher
	Bischof L, Kao C, Los F, Gonzalez M, Shen Z, Briggs S, et al. Activation of the unfolded protein response is required for defenses against bacterial pore-forming toxin in vivo. PLoS Pathog. 2008;4:e1000176 pubmed publisher
	Owaki T, Asakawa M, Fukai F, Mizuguchi J, Yoshimoto T. IL-27 induces Th1 differentiation via p38 MAPK/T-bet- and intercellular adhesion molecule-1/LFA-1/ERK1/2-dependent pathways. J Immunol. 2006;177:7579-87 pubmed
	Osmanagic Myers S, Gregor M, Walko G, Burgstaller G, Reipert S, Wiche G. Plectin-controlled keratin cytoarchitecture affects MAP kinases involved in cellular stress response and migration. J Cell Biol. 2006;174:557-68 pubmed
	Porcellini S, Traggiai E, Schenk U, Ferrera D, Matteoli M, Lanzavecchia A, et al. Regulation of peripheral T cell activation by calreticulin. J Exp Med. 2006;203:461-71 pubmed

product information

SKU :

9215S

Product-Name :

Phospho-p38 MAPK (Thr180/Tyr182) (3D7) Rabbit mAb

Size :

200 ul

Price-(USD) :

274 USD

Species-x-Reactivity :

H, M, R, Mk, Dm, Pg, Sc, (Hm, B)

Applications :

Flow cytometry

Product-Category :

MAP Kinase Signaling

Shipping-Temp :

COLD

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

Host :

Rabbit

Target :

p38-alpha MAPK (Thr180/Tyr182) phosphate/p38-beta MAPK (Thr188/Tyr190) phosphate/p38-delta MAPK (Thr180/Tyr182) phosphate/p38-gamma MAPK (Thr183/Tyr185) phosphate

more info or order :

Cell Signaling Technology product webpage