| Published Application/Species/Dilution | Reference |
|---|
- western blot; rat; fig S3
| Simard E, Söllradl T, Maltais J, Boucher J, D'Orléans-Juste P, Grandbois M. Receptor for Advanced Glycation End-Products Signaling Interferes with the Vascular Smooth Muscle Cell Contractile Phenotype and Function. PLoS ONE. 2015;10:e0128881 pubmed publisher |
| Wang Y, Xiao X, Li N, Yang D, Xing Y, Huo R, et al. Oestrogen inhibits BMP4-induced BMP4 expression in cardiomyocytes: a potential mechanism of oestrogen-mediated protection against cardiac hypertrophy. Br J Pharmacol. 2015;172:5586-95 pubmed publisher |
| Richter E, Harms M, Ventz K, Gierok P, Chilukoti R, Hildebrandt J, et al. A multi-omics approach identifies key hubs associated with cell type-specific responses of airway epithelial cells to staphylococcal alpha-toxin. PLoS ONE. 2015;10:e0122089 pubmed publisher |
- western blot; human; 1:1000
| Graziani G, Artuso S, De Luca A, Muzi A, Rotili D, Scimeca M, et al. A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib. Biochem Pharmacol. 2015;95:16-27 pubmed publisher |
- western blot; mouse; 1:1000
| Kim H, Kim I, Dong Y, Lee I, Kim J, Kim J, et al. Melanogenesis-inducing effect of cirsimaritin through increases in microphthalmia-associated transcription factor and tyrosinase expression. Int J Mol Sci. 2015;16:8772-88 pubmed publisher |
| Kim S, Kim W, Yoon J, Ji J, Morgan M, Cho H, et al. Upregulated RIP3 Expression Potentiates MLKL Phosphorylation-Mediated Programmed Necrosis in Toxic Epidermal Necrolysis. J Invest Dermatol. 2015;135:2021-30 pubmed publisher |
| Xu T, Pan Z, Dong M, Yu C, Niu Y. Ferulic acid suppresses activation of hepatic stellate cells through ERK1/2 and Smad signaling pathways in vitro. Biochem Pharmacol. 2015;93:49-58 pubmed publisher |
- western blot; mouse; 1:1000; fig 10
| Seaberg B, Henslee G, Wang S, Paez-Colasante X, Landreth G, Rimer M. Muscle-derived extracellular signal-regulated kinases 1 and 2 are required for the maintenance of adult myofibers and their neuromuscular junctions. Mol Cell Biol. 2015;35:1238-53 pubmed publisher |
- western blot; mouse; fig 2
| Wang S, Amato K, Song W, Youngblood V, Lee K, Boothby M, et al. Regulation of endothelial cell proliferation and vascular assembly through distinct mTORC2 signaling pathways. Mol Cell Biol. 2015;35:1299-313 pubmed publisher |
- western blot; mouse; 1:2000
| Dahlhoff M, Schafer M, Muzumdar S, Rose C, Schneider M. ERBB3 is required for tumor promotion in a mouse model of skin carcinogenesis. Mol Oncol. 2015;9:1825-33 pubmed publisher |
| Nakahara T, Tanaka K, Ohno S, Egawa N, Yugawa T, Kiyono T. Activation of NF-κB by human papillomavirus 16 E1 limits E1-dependent viral replication through degradation of E1. J Virol. 2015;89:5040-59 pubmed publisher |
- western blot; human; 1:1000
| Carvallo L, Lopez L, Che F, Lim J, Eugenin E, Williams D, et al. Buprenorphine decreases the CCL2-mediated chemotactic response of monocytes. J Immunol. 2015;194:3246-58 pubmed publisher |
| Krokowski D, Jobava R, Guan B, Farabaugh K, Wu J, Majumder M, et al. Coordinated Regulation of the Neutral Amino Acid Transporter SNAT2 and the Protein Phosphatase Subunit GADD34 Promotes Adaptation to Increased Extracellular Osmolarity. J Biol Chem. 2015;290:17822-37 pubmed publisher |
- immunocytochemistry; human
- western blot; rat
| Zhang L, Wang H, Ding K, Xu J. FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells. Toxicol Lett. 2015;236:43-59 pubmed publisher |
| Picot N, Guerrette R, Beauregard A, Jean S, Michaud P, Harquail J, et al. Mammaglobin 1 promotes breast cancer malignancy and confers sensitivity to anticancer drugs. Mol Carcinog. 2015;: pubmed publisher |
| Greenfeld H, Takasaki K, Walsh M, Ersing I, Bernhardt K, Ma Y, et al. TRAF1 Coordinates Polyubiquitin Signaling to Enhance Epstein-Barr Virus LMP1-Mediated Growth and Survival Pathway Activation. PLoS Pathog. 2015;11:e1004890 pubmed publisher |
| Azimzadeh O, Sievert W, Sarioglu H, Merl-Pham J, Yentrapalli R, Bakshi M, et al. Integrative proteomics and targeted transcriptomics analyses in cardiac endothelial cells unravel mechanisms of long-term radiation-induced vascular dysfunction. J Proteome Res. 2015;14:1203-19 pubmed publisher |
- western blot; human; 1:1000
| Wang S, Awad K, Elinoff J, Dougherty E, Ferreyra G, Wang J, et al. G Protein-coupled Receptor 40 (GPR40) and Peroxisome Proliferator-activated Receptor γ (PPARγ): AN INTEGRATED TWO-RECEPTOR SIGNALING PATHWAY. J Biol Chem. 2015;290:19544-57 pubmed publisher |
- western blot; human; 1:1000; fig 3
| Tanaka T, Iino M. Sec8 regulates cytokeratin8 phosphorylation and cell migration by controlling the ERK and p38 MAPK signalling pathways. Cell Signal. 2015;27:1110-9 pubmed publisher |
- western blot; mouse; fig 1, 2
| Ashraf M, Ebner M, Wallner C, Haller M, Khalid S, Schwelberger H, et al. A p38MAPK/MK2 signaling pathway leading to redox stress, cell death and ischemia/reperfusion injury. Cell Commun Signal. 2014;12:6 pubmed publisher |
| Grünberg J, Hammarstedt A, Hedjazifar S, Smith U. The Novel Secreted Adipokine WNT1-inducible Signaling Pathway Protein 2 (WISP2) Is a Mesenchymal Cell Activator of Canonical WNT. J Biol Chem. 2014;289:6899-907 pubmed publisher |
| Shin J, Le Dour C, Sera F, Iwata S, Homma S, Joseph L, et al. Depletion of lamina-associated polypeptide 1 from cardiomyocytes causes cardiac dysfunction in mice. Nucleus. 2014;5:260-459 pubmed publisher |
- western blot; mouse; fig 5
| Chen J, Lazarenko O, Zhang J, Blackburn M, Ronis M, Badger T. Diet-derived phenolic acids regulate osteoblast and adipocyte lineage commitment and differentiation in young mice. J Bone Miner Res. 2014;29:1043-53 pubmed publisher |
| Ashlin T, Buckley M, Salter R, Johnson J, Kwan A, Ramji D. The anti-atherogenic cytokine interleukin-33 inhibits the expression of a disintegrin and metalloproteinase with thrombospondin motifs-1, -4 and -5 in human macrophages: Requirement of extracellular signal-regulated kinase, c-Jun N-terminal kinase and pho. Int J Biochem Cell Biol. 2014;46:113-23 pubmed publisher |
| Park E, Kim B, Lee E, Chang E, Kim D, Choi S, et al. Targeting of receptor for advanced glycation end products suppresses cyst growth in polycystic kidney disease. J Biol Chem. 2014;289:9254-62 pubmed publisher |
- western blot; mouse; fig 5
| Lin H, Lin S, Chung Y, Vonderfecht S, Camden J, Flodby P, et al. Dynamic involvement of ATG5 in cellular stress responses. Cell Death Dis. 2014;5:e1478 pubmed publisher |
| Baek J, Kim J, Cheon Y, Park S, Ahn S, Yoon K, et al. Aconitum pseudo-laeve var. erectum inhibits receptor activator of nuclear factor kappa-B ligand-induced osteoclastogenesis via the c-Fos/nuclear factor of activated T-cells, cytoplasmic 1 signaling pathway and prevents lipopolysaccharide-induced bone loss. Molecules. 2014;19:11628-44 pubmed publisher |
| Cazanave S, Wang X, Zhou H, Rahmani M, Grant S, Durrant D, et al. Degradation of Keap1 activates BH3-only proteins Bim and PUMA during hepatocyte lipoapoptosis. Cell Death Differ. 2014;21:1303-12 pubmed publisher |
| Prickett T, Zerlanko B, Hill V, Gartner J, Qutob N, Jiang J, et al. Somatic mutation of GRIN2A in malignant melanoma results in loss of tumor suppressor activity via aberrant NMDAR complex formation. J Invest Dermatol. 2014;134:2390-8 pubmed publisher |
| Hu J, Cheng Y, Li Y, Jin Z, Pan Y, Liu G, et al. microRNA-128 plays a critical role in human non-small cell lung cancer tumourigenesis, angiogenesis and lymphangiogenesis by directly targeting vascular endothelial growth factor-C. Eur J Cancer. 2014;50:2336-50 pubmed publisher |
- western blot; human; 1:1000
| Zhong X, Wang H, Huang S. Endothelin-1 induces interleukin-18 expression in human osteoblasts. Arch Oral Biol. 2014;59:289-96 pubmed publisher |
- western blot; mouse; fig s2
| Takahashi N, Vereecke L, Bertrand M, Duprez L, Berger S, Divert T, et al. RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis. Nature. 2014;513:95-9 pubmed publisher |
- western blot; mouse; 1:10000
| Lee S, Xu G, Jay T, Bhatta S, Kim K, Jung S, et al. Opposing effects of membrane-anchored CX3CL1 on amyloid and tau pathologies via the p38 MAPK pathway. J Neurosci. 2014;34:12538-46 pubmed publisher |
| Hamada K, Osaka M, Yoshida M. Cell density impacts epigenetic regulation of cytokine-induced E-selectin gene expression in vascular endothelium. PLoS ONE. 2014;9:e90502 pubmed publisher |
| Czaplinska D, Turczyk L, Grudowska A, Mieszkowska M, Lipinska A, Skladanowski A, et al. Phosphorylation of RSK2 at Tyr529 by FGFR2-p38 enhances human mammary epithelial cells migration. Biochim Biophys Acta. 2014;1843:2461-70 pubmed publisher |
| Zhao X, Zhu L, Chang Q, Jiang C, You Y, Luo T, et al. C-type lectin receptor dectin-3 mediates trehalose 6,6'-dimycolate (TDM)-induced Mincle expression through CARD9/Bcl10/MALT1-dependent nuclear factor (NF)-κB activation. J Biol Chem. 2014;289:30052-62 pubmed publisher |
- western blot; mouse; 1:1000
| Zhang Y, Zhang X, Gao L, Liu Y, Jiang D, Chen K, et al. Growth/differentiation factor 1 alleviates pressure overload-induced cardiac hypertrophy and dysfunction. Biochim Biophys Acta. 2014;1842:232-44 pubmed publisher |
| Lemire B, Debigare R, Dubé A, Thériault M, Cote C, Maltais F. MAPK signaling in the quadriceps of patients with chronic obstructive pulmonary disease. J Appl Physiol (1985). 2012;113:159-66 pubmed publisher |
| Garcia D, de Castro-Faria-Neto H, da Silva C, de Souza e Souza K, Gonçalves-de-Albuquerque C, Silva A, et al. Na/K-ATPase as a target for anticancer drugs: studies with perillyl alcohol. Mol Cancer. 2015;14:105 pubmed publisher |
| Byun K, Bayarsaikhan D, Bayarsaikhan E, Son M, Oh S, Lee J, et al. Microglial AGE-albumin is critical in promoting alcohol-induced neurodegeneration in rats and humans. PLoS ONE. 2014;9:e104699 pubmed publisher |
| Fan Y, Cheng J, Vasudevan S, Patel R, Liang L, Xu X, et al. TAK1 inhibitor 5Z-7-oxozeaenol sensitizes neuroblastoma to chemotherapy. Apoptosis. 2013;18:1224-34 pubmed publisher |
| Lee W, Lee H, Vo M, Kim H, Ko M, Im Y, et al. Casein kinase 2 regulates the mRNA-destabilizing activity of tristetraprolin. J Biol Chem. 2011;286:21577-87 pubmed publisher |
| Miyaji M, Kortum R, Surana R, Li W, Woolard K, Simpson R, et al. Genetic evidence for the role of Erk activation in a lymphoproliferative disease of mice. Proc Natl Acad Sci U S A. 2009;106:14502-7 pubmed publisher |
| Rohani M, DiJulio D, An J, Hacker B, Dale B, Chung W. PAR1- and PAR2-induced innate immune markers are negatively regulated by PI3K/Akt signaling pathway in oral keratinocytes. BMC Immunol. 2010;11:53 pubmed publisher |
| Gehani S, Agrawal-Singh S, Dietrich N, Christophersen N, Helin K, Hansen K. Polycomb group protein displacement and gene activation through MSK-dependent H3K27me3S28 phosphorylation. Mol Cell. 2010;39:886-900 pubmed publisher |
| Hsu J, Hsieh Y, Kan W, Chen J, Choudhry M, Schwacha M, et al. Role of p38 mitogen-activated protein kinase pathway in estrogen-mediated cardioprotection following trauma-hemorrhage. Am J Physiol Heart Circ Physiol. 2007;292:H2982-7 pubmed |
