product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-p70 S6 Kinase (Ser371) Antibody
catalog :
9208
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, other
citations: 22
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 5a
Zhang X, Fan J, Wang S, Li Y, Wang Y, Li S, et al. Targeting CD47 and Autophagy Elicited Enhanced Antitumor Effects in Non-Small Cell Lung Cancer. Cancer Immunol Res. 2017;5:363-375 pubmed publisher
  • western blot; human; fig 2
Jung J, Kang K, Kim J, Hong S, Park Y, Kim B. CXCR2 Inhibition in Human Pluripotent Stem Cells Induces Predominant Differentiation to Mesoderm and Endoderm Through Repression of mTOR, ?-Catenin, and hTERT Activities. Stem Cells Dev. 2016;25:1006-19 pubmed publisher
  • western blot; human; loading ...; fig 5a
Ma X, Guo P, Qiu Y, Mu K, Zhu L, Zhao W, et al. Loss of AIM2 expression promotes hepatocarcinoma progression through activation of mTOR-S6K1 pathway. Oncotarget. 2016;7:36185-36197 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 7a
Xu Z, Mei F, Liu H, Sun C, Zheng Z. C-C Motif Chemokine Receptor 9 Exacerbates Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction. J Am Heart Assoc. 2016;5: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4b
Pawar K, Hanisch C, Palma Vera S, Einspanier R, Sharbati S. Down regulated lncRNA MEG3 eliminates mycobacteria in macrophages via autophagy. Sci Rep. 2016;6:19416 pubmed publisher
  • western blot; rat; fig s3
Wang J, Cao Y, Li Q, Yang Y, Jin M, Chen D, et al. A pivotal role of FOS-mediated BECN1/Beclin 1 upregulation in dopamine D2 and D3 receptor agonist-induced autophagy activation. Autophagy. 2015;11:2057-2073 pubmed publisher
  • western blot; human; 1:1000; fig 4
Rabinovich S, Adler L, Yizhak K, Sarver A, Silberman A, Agron S, et al. Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis. Nature. 2015;527:379-383 pubmed publisher
  • western blot; mouse; 1:1000; fig 2
Marchi S, Corricelli M, Trapani E, Bravi L, Pittaro A, Delle Monache S, et al. Defective autophagy is a key feature of cerebral cavernous malformations. EMBO Mol Med. 2015;7:1403-17 pubmed publisher
  • western blot; rat; 1:500; loading ...; fig 5a
Xie R, He W, Shen M, Shou X, Wang Y, Bao W, et al. Specific inhibition of mTOR pathway induces anti-proliferative effect and decreases the hormone secretion in cultured pituitary adenoma cells. J Neurooncol. 2015;125:79-89 pubmed publisher
  • other; mouse; 1:1000; fig s1
Chiang C, Uzoma I, Lane D, Memišević V, Alem F, Yao K, et al. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Front Microbiol. 2015;6:683 pubmed publisher
  • western blot; rat
  • immunocytochemistry; human
Zhang L, Wang H, Ding K, Xu J. FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells. Toxicol Lett. 2015;236:43-59 pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 6c
Li X, Gu S, Ling Y, Shen C, Cao X, Xie R. p53 inhibition provides a pivotal protective effect against ischemia-reperfusion injury in vitro via mTOR signaling. Brain Res. 2015;1605:31-8 pubmed publisher
  • western blot; mouse; 1:2000; loading ...; fig 4a
Umberger N, Caspary T. Ciliary transport regulates PDGF-AA/αα signaling via elevated mammalian target of rapamycin signaling and diminished PP2A activity. Mol Biol Cell. 2015;26:350-8 pubmed publisher
  • western blot; mouse; 1:1000; fig 4
Morris S, Carter K, Baek J, Koszarek A, Yeh M, Knoblaugh S, et al. TGF-? signaling alters the pattern of liver tumorigenesis induced by Pten inactivation. Oncogene. 2015;34:3273-82 pubmed publisher
  • western blot; human; 1:1000
  • western blot; rat; 1:1000
Tian H, Wang L, Cai R, Zheng L, Guo L. Identification of protein network alterations upon retinal ischemia-reperfusion injury by quantitative proteomics using a Rattus norvegicus model. PLoS ONE. 2014;9:e116453 pubmed publisher
  • western blot; mouse; 1:100; fig 3
Betschinger J, Nichols J, Dietmann S, Corrin P, Paddison P, Smith A. Exit from pluripotency is gated by intracellular redistribution of the bHLH transcription factor Tfe3. Cell. 2013;153:335-47 pubmed publisher
Zheng K, Jiang Y, Liao C, Hu X, Li Y, Zeng Y, et al. NOX2-Mediated TFEB Activation and Vacuolization Regulate Lysosome-Associated Cell Death Induced by Gypenoside L, a Saponin Isolated from Gynostemma pentaphyllum. J Agric Food Chem. 2017;65:6625-6637 pubmed publisher
Zhou L, He X, Gao B, Xiong S. Inhibition of Histone Deacetylase Activity Aggravates Coxsackievirus B3-Induced Myocarditis by Promoting Viral Replication and Myocardial Apoptosis. J Virol. 2015;89:10512-23 pubmed publisher
Seok S, Fu T, Choi S, Li Y, Zhu R, Kumar S, et al. Transcriptional regulation of autophagy by an FXR-CREB axis. Nature. 2014;516:108-11 pubmed publisher
Castillo K, Valenzuela V, Matus S, Nassif M, Onate M, Fuentealba Y, et al. Measurement of autophagy flux in the nervous system in vivo. Cell Death Dis. 2013;4:e917 pubmed publisher
Fong J, Jacobs R, Moravec D, Uppada S, Botting G, Nlend M, et al. Alternative signaling pathways as potential therapeutic targets for overcoming EGFR and c-Met inhibitor resistance in non-small cell lung cancer. PLoS ONE. 2013;8:e78398 pubmed publisher
Kim D, Akcakanat A, Singh G, Sharma C, Meric Bernstam F. Regulation and localization of ribosomal protein S6 kinase 1 isoforms. Growth Factors. 2009;27:12-21 pubmed publisher
product information
SKU :
9208S
Product-Name :
Phospho-p70 S6 Kinase (Ser371) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Western blot
Product-Category :
PI3K / Akt Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
70, 85
Host :
Rabbit
Target :
p70 S6k1 (Ser394) phosphate
Primary-Protein :
p70S6K
Alt-Names :
70 kDa ribosomal protein S6 kinase 1,KS6B1,P70S6K1,PS6K,RPS6KB1,Ribosomal protein S6 kinase I,Ribosomal protein S6 kinase beta-1,S6K,S6K-beta-1,S6K1,STK14A,Serine/threonine-protein kinase 14A,p70 S6 kinase alpha,p70 S6 kinase, alpha 1,p70 S6 kinase, alpha 2,p70 S6K-alpha,p70 S6KA,p70 ribosomal S6 kinase alpha,p70(S6K)-alpha,p70-S6K,p70-S6K 1,p70-alpha,ribosomal protein S6 kinase, 70kDa, polypeptide 1,serine/threonine kinase 14 alpha
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.