product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-p70 S6 Kinase (Thr389) (1A5) Mouse mAb
catalog :
9206L
quantity :
300 ul
price :
658 USD
clonality :
monoclonal
host :
mouse
antigen modification :
phosphorylated
clone name :
1A5
reactivity :
human, mouse, rat, pig, fruit fly
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
Cell Signaling Technology product webpage
citations: 16
Published Application/Species/DilutionReference
  • western blot; human; 1:1000; fig 6
Dirks M, Wall B, Kramer I, Zorenc A, Goessens J, Gijsen A, et al. A single session of neuromuscular electrical stimulation does not augment postprandial muscle protein accretion. Am J Physiol Endocrinol Metab. 2016;311:E278-85 pubmed publisher
  • western blot; mouse; fig 4
Han X, Tai H, Wang X, Wang Z, Zhou J, Wei X, et al. AMPK activation protects cells from oxidative stress-induced senescence via autophagic flux restoration and intracellular NAD(+) elevation. Aging Cell. 2016;15:416-27 pubmed publisher
  • western blot; human; fig 7
Pivonello C, Negri M, De Martino M, Napolitano M, De Angelis C, Provvisiero D, et al. The dual targeting of insulin and insulin-like growth factor 1 receptor enhances the mTOR inhibitor-mediated antitumor efficacy in hepatocellular carcinoma. Oncotarget. 2016;7:9718-31 pubmed publisher
  • western blot; mouse; fig 7
Wang X, Bey A, Katz B, Badea A, Kim N, David L, et al. Altered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism. Nat Commun. 2016;7:11459 pubmed publisher
  • western blot; human; fig 4
Kocher B, White L, Piwnica-Worms D. DAPK3 suppresses acini morphogenesis and is required for mouse development. Mol Cancer Res. 2015;13:358-67 pubmed publisher
  • western blot; human; fig 6
Zhang T, Zhou Q, Ogmundsdottir M, Möller K, Siddaway R, Larue L, et al. Mitf is a master regulator of the v-ATPase, forming a control module for cellular homeostasis with v-ATPase and TORC1. J Cell Sci. 2015;128:2938-50 pubmed publisher
  • immunohistochemistry; human; 1:2000
Jespersen J, Mikkelsen U, Nedergaard A, Thorlund J, Schjerling P, Suetta C, et al. Alterations in molecular muscle mass regulators after 8 days immobilizing Special Forces mission. Scand J Med Sci Sports. 2015;25:175-83 pubmed publisher
  • western blot; fruit fly; fig 1
Takáts S, Varga A, Pircs K, Juhasz G. Loss of Drosophila Vps16A enhances autophagosome formation through reduced Tor activity. Autophagy. 2015;11:1209-15 pubmed publisher
  • western blot; human
Zhang L, Dai F, Cui L, Jing H, Fan P, Tan X, et al. Novel role for TRPC4 in regulation of macroautophagy by a small molecule in vascular endothelial cells. Biochim Biophys Acta. 2015;1853:377-87 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100
Ren H, Wang J, Yang F, Zhang X, Wang A, Sun L, et al. Cytoplasmic TRAF4 contributes to the activation of p70s6k signaling pathway in breast cancer. Oncotarget. 2015;6:4080-96 pubmed
  • western blot; pig; 1:2000
Columbus D, Steinhoff-Wagner J, Suryawan A, Nguyen H, Hernandez-Garcia A, Fiorotto M, et al. Impact of prolonged leucine supplementation on protein synthesis and lean growth in neonatal pigs. Am J Physiol Endocrinol Metab. 2015;309:E601-10 pubmed publisher
  • western blot; human; fig s2
Felzen V, Hiebel C, Koziollek-Drechsler I, Reißig S, Wolfrum U, Kogel D, et al. Estrogen receptor α regulates non-canonical autophagy that provides stress resistance to neuroblastoma and breast cancer cells and involves BAG3 function. Cell Death Dis. 2015;6:e1812 pubmed publisher
  • western blot; human
Subramani R, Lopez-Valdez R, Arumugam A, Nandy S, Boopalan T, Lakshmanaswamy R. Targeting insulin-like growth factor 1 receptor inhibits pancreatic cancer growth and metastasis. PLoS ONE. 2014;9:e97016 pubmed publisher
Guertin D, Stevens D, Saitoh M, Kinkel S, Crosby K, Sheen J, et al. mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice. Cancer Cell. 2009;15:148-59 pubmed publisher
Park J, Arakawa-Takeuchi S, Jinno S, Okayama H. Rho-associated kinase connects a cell cycle-controlling anchorage signal to the mammalian target of rapamycin pathway. J Biol Chem. 2011;286:23132-41 pubmed publisher
Cao R, Lee B, Cho H, Saklayen S, Obrietan K. Photic regulation of the mTOR signaling pathway in the suprachiasmatic circadian clock. Mol Cell Neurosci. 2008;38:312-24 pubmed publisher
product information
SKU :
9206L
Product-Name :
Phospho-p70 S6 Kinase (Thr389) (1A5) Mouse mAb
Size :
300 ul
Price-(USD) :
658 USD
Species-x-Reactivity :
H, M, R, Mk, Dm
Applications :
Western blot
Product-Category :
PI3K / Akt Signaling
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
70, 85
Host :
Mouse
Target :
p70 S6k1 (Thr412) phosphate
Primary-Protein :
p70S6K
Alt-Names :
70 kDa ribosomal protein S6 kinase 1,KS6B1,P70S6K1,PS6K,RPS6KB1,Ribosomal protein S6 kinase I,Ribosomal protein S6 kinase beta-1,S6K,S6K-beta-1,S6K1,STK14A,Serine/threonine-protein kinase 14A,p70 S6 kinase alpha,p70 S6 kinase, alpha 1,p70 S6 kinase, alpha 2,p70 S6K-alpha,p70 S6KA,p70 ribosomal S6 kinase alpha,p70(S6K)-alpha,p70-S6K,p70-S6K 1,p70-alpha,ribosomal protein S6 kinase, 70kDa, polypeptide 1,serine/threonine kinase 14 alpha
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.