Phospho-CREB (Ser133) (87G3) Rabbit mAb | Cell Signaling Technology 9198 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Phospho-CREB (Ser133) (87G3) Rabbit mAb

catalog :

9198

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

African green monkey, human, mouse, rat, dogs, domestic sheep

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, EMSA, chromatin immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section, other

more info or order :

Cell Signaling Technology product webpage

citations: 126

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 8d	Tang Y, Li K, Hu B, Cai Z, Li J, Tao H, et al. Fatty acid binding protein 5 promotes the proliferation, migration, and invasion of hepatocellular carcinoma cells by degradation of Krüppel-like factor 9 mediated by miR-889-5p via cAMP-response element binding protein. Cancer Biol Ther. 2022;23:424-438 pubmed publisher
western blot; mouse; 1:1000; fig 5h	Shi H, Wu D, Chen R, Li N, Zhu L. Requirement of hippocampal DG nNOS-CAPON dissociation for the anxiolytic and antidepressant effects of fluoxetine. Theranostics. 2022;12:3656-3675 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 3a	Merino B, Casanueva xc1 lvarez E, Quesada I, Gonz xe1 lez Casimiro C, Fern xe1 ndez D xed az C, Postigo Casado T, et al. Insulin-degrading enzyme ablation in mouse pancreatic alpha cells triggers cell proliferation, hyperplasia and glucagon secretion dysregulation. Diabetologia. 2022;65:1375-1389 pubmed publisher
western blot; human; 1:500; loading ...; fig 4b, 5a immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 7c western blot; mouse; 1:500; loading ...; fig 8b	Shrestha J, Santerre M, Allen C, Arjona S, Merali C, Mukerjee R, et al. HIV-1 gp120 Impairs Spatial Memory Through Cyclic AMP Response Element-Binding Protein. Front Aging Neurosci. 2022;14:811481 pubmed publisher
immunohistochemistry - paraffin section; human; loading ...; fig 1c, 4d western blot; human; loading ...; fig 1b, 2a	Cyra M, Schulte M, Berthold R, Heinst L, Jansen E, Gr xfc newald I, et al. SS18-SSX drives CREB activation in synovial sarcoma. Cell Oncol (Dordr). 2022;45:399-413 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 6a	Liu Y, Hu P, Zhai S, Feng W, Zhang R, Li Q, et al. Aquaporin 4 deficiency eliminates the beneficial effects of voluntary exercise in a mouse model of Alzheimer's disease. Neural Regen Res. 2022;17:2079-2088 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 5a	Wang Y, Han J, Zhu J, Zhang M, Ju M, Du Y, et al. GluN2A/ERK/CREB Signaling Pathway Involved in Electroacupuncture Regulating Hypothalamic-Pituitary-Adrenal Axis Hyperactivity. Front Neurosci. 2021;15:703044 pubmed publisher
immunohistochemistry; mouse; fig 6c	Cheng C, Xue F, Sui W, Meng L, Xie L, Zhang C, et al. Deletion of natriuretic peptide receptor C alleviates adipose tissue inflammation in hypercholesterolemic Apolipoprotein E knockout mice. J Cell Mol Med. 2021;25:9837-9850 pubmed publisher
western blot; mouse; loading ...; fig 6a	Wang Q, Qin F, Wang H, Yang H, Liu Q, Li Z, et al. Effect of Electro-Acupuncture at ST36 and SP6 on the cAMP -CREB Pathway and mRNA Expression Profile in the Brainstem of Morphine Tolerant Mice. Front Neurosci. 2021;15:698967 pubmed publisher
western blot; mouse; loading ...; fig 4	Lim D, Kim M, Yoon M, Lee J, Lee C, Um M. 1,3-Dicaffeoylquinic Acid as an Active Compound of Arctium lappa Root Extract Ameliorates Depressive-Like Behavior by Regulating Hippocampal Nitric Oxide Synthesis in Ovariectomized Mice. Antioxidants (Basel). 2021;10: pubmed publisher
western blot; human; 1:1000; loading ...; fig 5f	Gonzalez Rellan M, Fondevila M, Fernandez U, Rodríguez A, Varela Rey M, Veyrat Durebex C, et al. O-GlcNAcylated p53 in the liver modulates hepatic glucose production. Nat Commun. 2021;12:5068 pubmed publisher
immunohistochemistry - free floating section; mouse; loading ...; fig 6a western blot; mouse; loading ...; fig 4a immunocytochemistry; human; loading ...; fig 4c western blot; human; loading ...; fig 4b	Chen H, Teng Y, Chen X, Liu Z, Geng F, Liu Y, et al. Platelet-derived growth factor (PDGF)-BB protects dopaminergic neurons via activation of Akt/ERK/CREB pathways to upregulate tyrosine hydroxylase. CNS Neurosci Ther. 2021;27:1300-1312 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:200; fig 3s1g western blot; mouse; 1:1000; loading ...; fig 4d	Liu Z, Hussien A, Wang Y, Heckmann T, Gonzalez R, Karner C, et al. An adhesion G protein-coupled receptor is required in cartilaginous and dense connective tissues to maintain spine alignment. elife. 2021;10: pubmed publisher
western blot; rat; 1:1000; loading ...; fig 11a	Xiao J, Cai T, Fang Y, Liu R, Flores J, Wang W, et al. Activation of GPR40 attenuates neuroinflammation and improves neurological function via PAK4/CREB/KDM6B pathway in an experimental GMH rat model. J Neuroinflammation. 2021;18:160 pubmed publisher
western blot; mouse; loading ...; fig 5m	Swarnkar S, Avchalumov Y, Espadas I, Grinman E, Liu X, Raveendra B, et al. Molecular motor protein KIF5C mediates structural plasticity and long-term memory by constraining local translation. Cell Rep. 2021;36:109369 pubmed publisher
immunohistochemistry; rat; loading ...; fig 4a western blot; rat; loading ...; fig 2a	Kim Y, Lee J, Kim H, Jang J, Choung Y. Gap Junction-Mediated Intercellular Communication of cAMP Prevents CDDP-Induced Ototoxicity via cAMP/PKA/CREB Pathway. Int J Mol Sci. 2021;22: pubmed publisher
western blot; rat; 1:2000; loading ...; fig 6d, 6i	Liu L, Xu X, Qu Z, Zhao L, Zhang C, Li Z, et al. Determining 5HT7R's Involvement in Modifying the Antihyperalgesic Effects of Electroacupuncture on Rats With Recurrent Migraine. Front Neurosci. 2021;15:668616 pubmed publisher
western blot; mouse; loading ...; fig 4l	Basse A, Agerholm M, Farup J, Dalbram E, Nielsen J, Ørtenblad N, et al. Nampt controls skeletal muscle development by maintaining Ca2+ homeostasis and mitochondrial integrity. Mol Metab. 2021;53:101271 pubmed publisher
western blot; human; 1:1000; loading ...; fig 7e	Qiao Y, Jin T, Guan S, Cheng S, Wen S, Zeng H, et al. Long non-coding RNA Lnc-408 promotes invasion and metastasis of breast cancer cell by regulating LIMK1. Oncogene. 2021;40:4198-4213 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 10a, 10c	Yan C, Zeng T, Lee K, Nobis M, Loh K, Gou L, et al. Peripheral-specific Y1 receptor antagonism increases thermogenesis and protects against diet-induced obesity. Nat Commun. 2021;12:2622 pubmed publisher
western blot; human; 1:1000; loading ...; fig 1c	Arveseth C, Happ J, Hedeen D, Zhu J, Capener J, Klatt Shaw D, et al. Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunits. PLoS Biol. 2021;19:e3001191 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 8a	Wang J, Liu B, Xu Y, Yang M, Wang C, Song M, et al. Activation of CREB-mediated autophagy by thioperamide ameliorates β-amyloid pathology and cognition in Alzheimer's disease. Aging Cell. 2021;20:e13333 pubmed publisher
immunohistochemistry - paraffin section; mouse; fig 4g chromatin immunoprecipitation; mouse; loading ...; fig 3f immunocytochemistry; mouse; loading ...; fig 2c western blot; mouse; loading ...; fig 2a western blot; human; loading ...	Wan X, Zhou M, Huang F, Zhao N, Chen X, Wu Y, et al. AKT1-CREB stimulation of PDGFRα expression is pivotal for PTEN deficient tumor development. Cell Death Dis. 2021;12:172 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 6g	Deguise M, Pileggi C, De Repentigny Y, Beauvais A, Tierney A, Chehade L, et al. SMN Depleted Mice Offer a Robust and Rapid Onset Model of Nonalcoholic Fatty Liver Disease. Cell Mol Gastroenterol Hepatol. 2021;12:354-377.e3 pubmed publisher
western blot; human; loading ...; fig 6c	Bouhaddou M, Memon D, Meyer B, White K, Rezelj V, Correa Marrero M, et al. The Global Phosphorylation Landscape of SARS-CoV-2 Infection. Cell. 2020;182:685-712.e19 pubmed publisher
immunocytochemistry; rat; 1:100; loading ...; fig 3h western blot; rat; loading ...; fig 3n	Ruiz Velasco A, Zi M, Hille S, Azam T, Kaur N, Jiang J, et al. Targeting mir128-3p alleviates myocardial insulin resistance and prevents ischemia-induced heart failure. elife. 2020;9: pubmed publisher
immunohistochemistry; mouse; loading ...; fig 3f western blot; mouse; loading ...; fig 3e	Ngamsri K, Jans C, Putri R, Schindler K, Gamper Tsigaras J, Eggstein C, et al. Inhibition of CXCR4 and CXCR7 Is Protective in Acute Peritoneal Inflammation. Front Immunol. 2020;11:407 pubmed publisher
western blot; human; 1:1000; loading ...; fig 5a	Qin Y, Chen W, Jiang G, Zhou L, Yang X, Li H, et al. Interfering MSN-NONO complex-activated CREB signaling serves as a therapeutic strategy for triple-negative breast cancer. Sci Adv. 2020;6:eaaw9960 pubmed publisher
western blot; domestic sheep; 1:1000; loading ...; fig s10c	Schiffner R, Bischoff S, Lehmann T, Irintchev A, Nistor M, Lemke C, et al. Altered Cerebral Blood Flow and Potential Neuroprotective Effect of Human Relaxin-2 (Serelaxin) During Hypoxia or Severe Hypovolemia in a Sheep Model. Int J Mol Sci. 2020;21: pubmed publisher
western blot; human; loading ...; fig 6d	Aldonza M, Ku J, Hong J, Kim D, Yu S, Lee M, et al. Prior acquired resistance to paclitaxel relays diverse EGFR-targeted therapy persistence mechanisms. Sci Adv. 2020;6:eaav7416 pubmed publisher
western blot; mouse; 1:1500; loading ...; fig 1k	Xhima K, Markham Coultes K, Nedev H, Heinen S, Saragovi H, Hynynen K, et al. Focused ultrasound delivery of a selective TrkA agonist rescues cholinergic function in a mouse model of Alzheimer's disease. Sci Adv. 2020;6:eaax6646 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:800; loading ...; fig 6s1a	Podyma B, Johnson D, Sipe L, Remcho T, Battin K, Liu Y, et al. The p75 neurotrophin receptor in AgRP neurons is necessary for homeostatic feeding and food anticipation. elife. 2020;9: pubmed publisher
immunohistochemistry; mouse; 1:800; loading ...; fig s4a	Zhang B, Ma S, Rachmin I, He M, Baral P, Choi S, et al. Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells. Nature. 2020;577:676-681 pubmed publisher
western blot; mouse; loading ...; fig 11h western blot; rat; loading ...; fig 10h	Wang X, Deng Y, Gao Y, Dong Y, Wang F, Guan Z, et al. Activation of α7 nAChR by PNU-282987 improves synaptic and cognitive functions through restoring the expression of synaptic-associated proteins and the CaM-CaMKII-CREB signaling pathway. Aging (Albany NY). 2020;12:543-570 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 1m, 5e western blot; rat; 1:1000; loading ...; fig 2c	Ye J, Yin Y, Liu H, Fang L, Tao X, Wei L, et al. Tau inhibits PKA by nuclear proteasome-dependent PKAR2α elevation with suppressed CREB/GluA1 phosphorylation. Aging Cell. 2020;19:e13055 pubmed publisher
western blot; human; 1:1000; loading ...; fig 2d	Sonntag T, Moresco J, Yates J, Montminy M. The KLDpT activation loop motif is critical for MARK kinase activity. PLoS ONE. 2019;14:e0225727 pubmed publisher
western blot; human; 1:1000; loading ...; fig 4f	Eyre R, Alferez D, Santiago Gómez A, Spence K, McConnell J, Hart C, et al. Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling. Nat Commun. 2019;10:5016 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 6s1c	Nam H, Jeon S, An H, Yoo J, Lee H, Lee S, et al. Critical roles of ARHGAP36 as a signal transduction mediator of Shh pathway in lateral motor columnar specification. elife. 2019;8: pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 2k	Sun W, Chi S, Li Y, Ling S, Tan Y, Xu Y, et al. The mechanosensitive Piezo1 channel is required for bone formation. elife. 2019;8: pubmed publisher
western blot; human; loading ...; fig 4c	Jin H, Xue L, Mo L, Zhang D, Guo X, Xu J, et al. Downregulation of miR-200c stabilizes XIAP mRNA and contributes to invasion and lung metastasis of bladder cancer. Cell Adh Migr. 2019;13:236-248 pubmed publisher
western blot; human; loading ...; fig 2e	Sun Y, Liu Z, Cao X, Lu Y, Mi Z, He C, et al. Activation of P-TEFb by cAMP-PKA signaling in autosomal dominant polycystic kidney disease. Sci Adv. 2019;5:eaaw3593 pubmed publisher
western blot; human; 1:1000; loading ...; fig 1b	Jewell J, Fu V, Hong A, Yu F, Meng D, Melick C, et al. GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor. elife. 2019;8: pubmed publisher
western blot; mouse; 1:500; loading ...; fig 5e	Saito H, Gasser A, Bolamperti S, Maeda M, Matthies L, Jahn K, et al. TG-interacting factor 1 (Tgif1)-deficiency attenuates bone remodeling and blunts the anabolic response to parathyroid hormone. Nat Commun. 2019;10:1354 pubmed publisher
western blot; human; loading ...; fig s4f	Du H, LE Y, Sun F, Li K, Xu Y. ILF2 Directly Binds and Stabilizes CREB to Stimulate Malignant Phenotypes of Liver Cancer Cells. Anal Cell Pathol (Amst). 2019;2019:1575031 pubmed publisher
other; mouse; 1:50; loading ...; fig 3b	Joy M, Ben Assayag E, Shabashov Stone D, Liraz Zaltsman S, Mazzitelli J, Arenas M, et al. CCR5 Is a Therapeutic Target for Recovery after Stroke and Traumatic Brain Injury. Cell. 2019;176:1143-1157.e13 pubmed publisher
western blot; human; 1:1000; loading ...; fig 4c	Alam M, Yang D, Trivett A, Meyer T, Oppenheim J. HMGN1 and R848 Synergistically Activate Dendritic Cells Using Multiple Signaling Pathways. Front Immunol. 2018;9:2982 pubmed publisher
immunoprecipitation; mouse; loading ...; fig 7c western blot; mouse; 1:2000; loading ...; fig 1g	Walia M, Taylor S, Ho P, Martin T, Walkley C. Tolerance to sustained activation of the cAMP/Creb pathway activity in osteoblastic cells is enabled by loss of p53. Cell Death Dis. 2018;9:844 pubmed publisher
western blot; mouse; loading ...; fig 3d	Matesanz N, Nikolic I, Leiva M, Pulgarín Alfaro M, Santamans A, Bernardo E, et al. p38α blocks brown adipose tissue thermogenesis through p38δ inhibition. PLoS Biol. 2018;16:e2004455 pubmed publisher
immunohistochemistry - paraffin section; human; 1:50; loading ...; fig 7j western blot; human; 1:1000; fig s7b	Chhipa R, Fan Q, Anderson J, Muraleedharan R, Huang Y, Ciraolo G, et al. AMP kinase promotes glioblastoma bioenergetics and tumour growth. Nat Cell Biol. 2018;20:823-835 pubmed publisher
western blot; mouse; loading ...; fig 2i	Jun H, Yu H, Gong J, Jiang J, Qiao X, Perkey E, et al. An immune-beige adipocyte communication via nicotinic acetylcholine receptor signaling. Nat Med. 2018;24:814-822 pubmed publisher
immunohistochemistry - frozen section; rat; 1:300; fig 7g western blot; rat; 1:1000; fig 5d	Zhang P, Bi R, Gan Y. Glial interleukin-1β upregulates neuronal sodium channel 1.7 in trigeminal ganglion contributing to temporomandibular joint inflammatory hypernociception in rats. J Neuroinflammation. 2018;15:117 pubmed publisher
western blot; mouse; fig 5e	Markussen L, Winther S, Wicksteed B, Hansen J. GSK3 is a negative regulator of the thermogenic program in brown adipocytes. Sci Rep. 2018;8:3469 pubmed publisher
western blot; mouse; loading ...; fig 4a western blot; human; loading ...; fig s2a	Sutavani R, Phair I, Barker R, McFarlane A, Shpiro N, Lang S, et al. Differential control of Toll-like receptor 4-induced interleukin-10 induction in macrophages and B cells reveals a role for p90 ribosomal S6 kinases. J Biol Chem. 2018;293:2302-2317 pubmed publisher
western blot; human; loading ...; fig 3a immunohistochemistry - free floating section; rat; fig 6b	Balan I, Warnock K, Puche A, GONDRE LEWIS M, Aurelian L. Innately activated TLR4 signal in the nucleus accumbens is sustained by CRF amplification loop and regulates impulsivity. Brain Behav Immun. 2018;69:139-153 pubmed publisher
western blot; mouse; 1:500; loading ...; fig 4a	Jana M, Ghosh S, Pahan K. Upregulation of Myelin Gene Expression by a Physically-Modified Saline via Phosphatidylinositol 3-Kinase-Mediated Activation of CREB: Implications for Multiple Sclerosis. Neurochem Res. 2018;43:407-419 pubmed publisher
western blot; mouse; fig 5a	Cai X, Yuan Y, Liao Z, Xing K, Zhu C, Xu Y, et al. α-Ketoglutarate prevents skeletal muscle protein degradation and muscle atrophy through PHD3/ADRB2 pathway. FASEB J. 2018;32:488-499 pubmed publisher
western blot; rat; loading ...; fig 6o	Shi Y, Zhang X, Chen C, Tang M, Wang Z, Liang X, et al. Schisantherin A attenuates ischemia/reperfusion-induced neuronal injury in rats via regulation of TLR4 and C5aR1 signaling pathways. Brain Behav Immun. 2017;66:244-256 pubmed publisher
western blot; mouse; loading ...; fig 3g	Tsuda T, Takefuji M, Wettschureck N, Kotani K, Morimoto R, Okumura T, et al. Corticotropin releasing hormone receptor 2 exacerbates chronic cardiac dysfunction. J Exp Med. 2017;214:1877-1888 pubmed publisher
western blot; human; 1:1000; fig s1c	Frank S, Berger P, Ljungman M, Miranti C. Human prostate luminal cell differentiation requires NOTCH3 induction by p38-MAPK and MYC. J Cell Sci. 2017;130:1952-1964 pubmed publisher
western blot; mouse; fig 4a	Strickson S, Emmerich C, Goh E, Zhang J, Kelsall I, MacArtney T, et al. Roles of the TRAF6 and Pellino E3 ligases in MyD88 and RANKL signaling. Proc Natl Acad Sci U S A. 2017;114:E3481-E3489 pubmed publisher
immunocytochemistry; mouse; 1:300; loading ...; fig 8A	Wang S, Stanika R, Wang X, Hagen J, Kennedy M, Obermair G, et al. Densin-180 Controls the Trafficking and Signaling of L-Type Voltage-Gated Cav1.2 Ca2+ Channels at Excitatory Synapses. J Neurosci. 2017;37:4679-4691 pubmed publisher
immunohistochemistry - frozen section; mouse; loading ...; fig 2b	Dong E, Bachleda A, Xiong Y, Osawa S, Weiss E. Reduced phosphoCREB in MÃ¼ller glia during retinal degeneration in rd10 mice. Mol Vis. 2017;23:90-102 pubmed
immunocytochemistry; human; loading ...; fig s1	Loo L, Bougen Zhukov N, Tan W. Early spatiotemporal-specific changes in intermediate signals are predictive of cytotoxic sensitivity to TNFα and co-treatments. Sci Rep. 2017;7:43541 pubmed publisher
immunocytochemistry; human; loading ...; fig 5a western blot; human; loading ...; fig 4a	Bu Q, Wang A, Hamzah H, Waldman A, Jiang K, Dong Q, et al. CREB Signaling Is Involved in Rett Syndrome Pathogenesis. J Neurosci. 2017;37:3671-3685 pubmed publisher
western blot; mouse; loading ...; fig 3b	Akhmedov D, Mendoza Rodriguez M, Rajendran K, Rossi M, Wess J, Berdeaux R. Gs-DREADD Knock-In Mice for Tissue-Specific, Temporal Stimulation of Cyclic AMP Signaling. Mol Cell Biol. 2017;37: pubmed publisher
western blot; human; loading ...; fig 5a	Li Y, Buijs Gladdines J, Cant Barrett K, Stubbs A, Vroegindeweij E, Smits W, et al. IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study. PLoS Med. 2016;13:e1002200 pubmed publisher
western blot; human; loading ...; fig 7	Quinn S, Graves S, Dains McGahee C, Friedman E, Hassan H, Witkowski P, et al. Adenylyl cyclase 3/adenylyl cyclase-associated protein 1 (CAP1) complex mediates the anti-migratory effect of forskolin in pancreatic cancer cells. Mol Carcinog. 2017;56:1344-1360 pubmed publisher
western blot; human; 1:500; loading ...; fig 2a,s3a	Kim H, Kim M, Park Y, Park I, Kim T, Yang S, et al. Prostaglandin E2 Activates YAP and a Positive-Signaling Loop to Promote Colon Regeneration After Colitis but Also Carcinogenesis in Mice. Gastroenterology. 2017;152:616-630 pubmed publisher
western blot; mouse; loading ...; fig 2d	Park J, Kim S, Yoo J, Jang J, Lee A, Oh J, et al. Novel Neuroprotective Effects of Melanin-Concentrating Hormone in Parkinson's Disease. Mol Neurobiol. 2017;54:7706-7721 pubmed publisher
western blot; dogs; loading ...; tbl 1	Bulldan A, Shihan M, Goericke Pesch S, Scheiner Bobis G. Signaling events associated with gonadotropin releasing hormone-agonist-induced hormonal castration and its reversal in canines. Mol Reprod Dev. 2016;83:1092-1101 pubmed publisher
western blot; human; 1:1000; loading ...; fig 8f immunocytochemistry; dogs; 1:200; loading ...; fig s6a	Eccles R, Czajkowski M, Barth C, Müller P, McShane E, Grunwald S, et al. Bimodal antagonism of PKA signalling by ARHGAP36. Nat Commun. 2016;7:12963 pubmed publisher
western blot; human; 1:1000; fig st1	Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
immunocytochemistry; rat; 1:800; fig 1 western blot; rat; 1:1000; fig 1	Yan X, Liu J, Ye Z, Huang J, He F, Xiao W, et al. CaMKII-Mediated CREB Phosphorylation Is Involved in Ca2+-Induced BDNF mRNA Transcription and Neurite Outgrowth Promoted by Electrical Stimulation. PLoS ONE. 2016;11:e0162784 pubmed publisher
western blot; human; fig s2	Hong X, Liu W, Song R, Shah J, Feng X, Tsang C, et al. SOX9 is targeted for proteasomal degradation by the E3 ligase FBW7 in response to DNA damage. Nucleic Acids Res. 2016;44:8855-8869 pubmed
western blot; mouse; loading ...; fig 4b	Wang J, Zhou J, Kho D, Reiners J, Wu G. Role for DUSP1 (dual-specificity protein phosphatase 1) in the regulation of autophagy. Autophagy. 2016;12:1791-1803 pubmed
western blot; human; fig 2a	François S, Sen N, Mitton B, Xiao X, Sakamoto K, Arvin A. Varicella-Zoster Virus Activates CREB, and Inhibition of the pCREB-p300/CBP Interaction Inhibits Viral Replication In Vitro and Skin Pathogenesis In Vivo. J Virol. 2016;90:8686-97 pubmed publisher
western blot; human; 1:1000; fig 3	Qiao Y, Qian Y, Wang J, Tang X. Melanoma cell adhesion molecule stimulates yes-associated protein transcription by enhancing CREB activity via c-Jun/c-Fos in hepatocellular carcinoma cells. Oncol Lett. 2016;11:3702-3708 pubmed
western blot; mouse; fig 6	Tejada T, Tan L, Torres R, Calvert J, Lambert J, Zaidi M, et al. IGF-1 degradation by mouse mast cell protease 4 promotes cell death and adverse cardiac remodeling days after a myocardial infarction. Proc Natl Acad Sci U S A. 2016;113:6949-54 pubmed publisher
western blot; human; loading ...; fig 4d	Salvi V, Vermi W, Gianello V, Lonardi S, Gagliostro V, Naldini A, et al. Dendritic cell-derived VEGF-A plays a role in inflammatory angiogenesis of human secondary lymphoid organs and is driven by the coordinated activation of multiple transcription factors. Oncotarget. 2016;7:39256-39269 pubmed publisher
western blot; mouse; 1:1000; fig s4	Reinhard J, Kriz A, Galic M, Angliker N, Rajalu M, Vogt K, et al. The calcium sensor Copine-6 regulates spine structural plasticity and learning and memory. Nat Commun. 2016;7:11613 pubmed publisher
immunohistochemistry; rat; loading ...; fig 3a western blot; rat; loading ...; fig 2a	Bulldan A, Dietze R, Shihan M, Scheiner Bobis G. Non-classical testosterone signaling mediated through ZIP9 stimulates claudin expression and tight junction formation in Sertoli cells. Cell Signal. 2016;28:1075-85 pubmed publisher
western blot; human; 1:1000; loading ...; fig 2d	Natale C, Duperret E, Zhang J, Sadeghi R, Dahal A, O Brien K, et al. Sex steroids regulate skin pigmentation through nonclassical membrane-bound receptors. elife. 2016;5: pubmed publisher
western blot; human; 1:2000; fig 3 chromatin immunoprecipitation; mouse western blot; mouse; 1:2000; fig 1	Walia M, Ho P, Taylor S, Ng A, Gupte A, Chalk A, et al. Activation of PTHrP-cAMP-CREB1 signaling following p53 loss is essential for osteosarcoma initiation and maintenance. elife. 2016;5: pubmed publisher
western blot; human; loading ...; fig 2e	Park S, Lee J, Herbst R, Koo J. GSK-3? Is a Novel Target of CREB and CREB-GSK-3? Signaling Participates in Cell Viability in Lung Cancer. PLoS ONE. 2016;11:e0153075 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 10a	Anastasiadou S, KnÃ¶ll B. The multiple sclerosis drug fingolimod (FTY720) stimulates neuronal gene expression, axonal growth and regeneration. Exp Neurol. 2016;279:243-260 pubmed publisher
western blot; mouse; 1:1000; fig 3	Antony A, Paillard M, Moffat C, Juskeviciute E, Correnti J, Bolon B, et al. MICU1 regulation of mitochondrial Ca(2+) uptake dictates survival and tissue regeneration. Nat Commun. 2016;7:10955 pubmed publisher
western blot; mouse; 1:1000; fig 1	Johanns M, Lai Y, Hsu M, Jacobs R, Vertommen D, Van Sande J, et al. AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B. Nat Commun. 2016;7:10856 pubmed publisher
immunocytochemistry; mouse; 1:200; tbl 1 western blot; mouse; tbl 1	Papadopoulos D, Dietze R, Shihan M, Kirch U, Scheiner Bobis G. Dehydroepiandrosterone Sulfate Stimulates Expression of Blood-Testis-Barrier Proteins Claudin-3 and -5 and Tight Junction Formation via a GnÎ±11-Coupled Receptor in Sertoli Cells. PLoS ONE. 2016;11:e0150143 pubmed publisher
western blot; human immunohistochemistry - frozen section; mouse; fig 3 western blot; mouse; fig 3	Singh N, Kotla S, Kumar R, Rao G. Cyclic AMP Response Element Binding Protein Mediates Pathological Retinal Neovascularization via Modulating DLL4-NOTCH1 Signaling. EBioMedicine. 2015;2:1767-84 pubmed publisher
western blot; mouse; 1:1000; fig 6	Bian Y, Yang L, Wang Z, Wang Q, Zeng L, Xu G. Repeated Three-Hour Maternal Separation Induces Depression-Like Behavior and Affects the Expression of Hippocampal Plasticity-Related Proteins in C57BL/6N Mice. Neural Plast. 2015;2015:627837 pubmed publisher
western blot; mouse; 1:500; tbl 1	Bertoldo M, Guibert E, Faure M, Guillou F, RamÃ© C, Nadal Desbarats L, et al. Specific deletion of AMP-activated protein kinase (Î±1AMPK) in mouse Sertoli cells modifies germ cell quality. Mol Cell Endocrinol. 2016;423:96-112 pubmed publisher
western blot; mouse; 1:1000; fig 4a	Lee K, Hsieh Y, Yang Y, Chan C, Huang Y, Lin H. Aliskiren Reduces Hepatic steatosis and Epididymal Fat Mass and Increases Skeletal Muscle Insulin Sensitivity in High-Fat Diet-Fed Mice. Sci Rep. 2016;6:18899 pubmed publisher
western blot; rat; fig 5	Wang J, Cao Y, Li Q, Yang Y, Jin M, Chen D, et al. A pivotal role of FOS-mediated BECN1/Beclin 1 upregulation in dopamine D2 and D3 receptor agonist-induced autophagy activation. Autophagy. 2015;11:2057-2073 pubmed publisher
western blot; mouse; 1:1000; fig 5	Brai E, Marathe S, Astori S, Fredj N, Perry E, Lamy C, et al. Notch1 Regulates Hippocampal Plasticity Through Interaction with the Reelin Pathway, Glutamatergic Transmission and CREB Signaling. Front Cell Neurosci. 2015;9:447 pubmed publisher
chromatin immunoprecipitation; human; fig 4	Duan S, Yuan G, Liu X, Ren R, Li J, Zhang W, et al. PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype. Nat Commun. 2015;6:10068 pubmed publisher
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chromatin immunoprecipitation; mouse; loading ...; fig 5e EMSA; mouse; loading ...; fig 5d immunoprecipitation; mouse; loading ...; fig 5c western blot; mouse; loading ...; fig 4d	Zhang Y, Li W, Zhu M, Li Y, Xu Z, Zuo B. FHL3 differentially regulates the expression of MyHC isoforms through interactions with MyoD and pCREB. Cell Signal. 2016;28:60-73 pubmed publisher
immunohistochemistry - frozen section; mouse; fig 5 western blot; mouse; fig 5	Yang L, McKnight G. Hypothalamic PKA regulates leptin sensitivity and adiposity. Nat Commun. 2015;6:8237 pubmed publisher
western blot; human; fig 6	Lee N, Kwon J, Kim Y, Kim S, Park S, Xu W, et al. Vaccinia-related kinase 1 promotes hepatocellular carcinoma by controlling the levels of cell cycle regulators associated with G1/S transition. Oncotarget. 2015;6:30130-48 pubmed publisher
western blot; mouse; 1:1000; fig 6	Mehrabian M, Brethour D, Wang H, Xi Z, Rogaeva E, Schmitt Ulms G. The Prion Protein Controls Polysialylation of Neural Cell Adhesion Molecule 1 during Cellular Morphogenesis. PLoS ONE. 2015;10:e0133741 pubmed publisher
western blot; rat; fig 5	Kim K, Byeon G, Kim H, Baek S, Shin S, Koo S. Mechanical Antiallodynic Effect of Intrathecal Nefopam in a Rat Neuropathic Pain Model. J Korean Med Sci. 2015;30:1189-96 pubmed publisher
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western blot; mouse; 1:500; fig 5	Iglesias Bartolomé R, Torres D, Marone R, Feng X, Martin D, Simaan M, et al. Inactivation of a GÎ±(s)-PKA tumour suppressor pathway in skin stem cells initiates basal-cell carcinogenesis. Nat Cell Biol. 2015;17:793-803 pubmed publisher
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immunohistochemistry; mouse; 1:100; fig 5 western blot; mouse; 1:1000; fig 5	Wu C, Hung T, Chen C, Ke C, Lee C, Wang P, et al. Post-injury treatment with 7,8-dihydroxyflavone, a TrkB receptor agonist, protects against experimental traumatic brain injury via PI3K/Akt signaling. PLoS ONE. 2014;9:e113397 pubmed publisher
western blot; dogs; fig 3 immunocytochemistry; human; fig 5 western blot; human; fig 3	Noguchi S, Kumazaki M, Mori T, Baba K, Okuda M, Mizuno T, et al. Analysis of microRNA-203 function in CREB/MITF/RAB27a pathway: comparison between canine and human melanoma cells. Vet Comp Oncol. 2016;14:384-394 pubmed publisher
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western blot; mouse; fig s2b	Chu Y, GÃ³mez Rosso L, Huang P, Wang Z, Xu Y, Yao X, et al. Liver Med23 ablation improves glucose and lipid metabolism through modulating FOXO1 activity. Cell Res. 2014;24:1250-65 pubmed publisher
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immunohistochemistry; rat; 1:100; fig 4 western blot; rat; 1:1000; fig 3a	Chen L, Tiong C, Tsai C, Liao W, Yang S, Youn S, et al. Early-life sleep deprivation persistently depresses melatonin production and bio-energetics of the pineal gland: potential implications for the development of metabolic deficiency. Brain Struct Funct. 2015;220:663-76 pubmed publisher
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