product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Stat1 (42H3) Rabbit mAb
catalog :
9175
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
42H3
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section, proximity ligation assay
citations: 17
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:200; loading ...; fig 3a
Basu R, Wu S, Kopchick J. Targeting growth hormone receptor in human melanoma cells attenuates tumor progression and epithelial mesenchymal transition via suppression of multiple oncogenic pathways. Oncotarget. 2017;8:21579-21598 pubmed publisher
  • western blot; human; loading ...; fig 5d
Cayrol F, Praditsuktavorn P, Fernando T, Kwiatkowski N, Marullo R, Calvo Vidal M, et al. THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors. Nat Commun. 2017;8:14290 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; fig 1g
Gujam F, McMillan D, Edwards J. The relationship between total and phosphorylated STAT1 and STAT3 tumour cell expression, components of tumour microenvironment and survival in patients with invasive ductal breast cancer. Oncotarget. 2016;7:77607-77621 pubmed publisher
  • western blot; human; 1:200; fig st1
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  • western blot; mouse; fig 4c
Kim J, Weeratunga P, Kim M, Nikapitiya C, Lee B, Uddin M, et al. Inhibitory effects of an aqueous extract from Cortex Phellodendri on the growth and replication of broad-spectrum of viruses in vitro and in vivo. BMC Complement Altern Med. 2016;16:265 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig S6b
  • proximity ligation assay; mouse; 1:100; loading ...; fig 6i
Salvucci O, Ohnuki H, Maric D, Hou X, Li X, Yoon S, et al. EphrinB2 controls vessel pruning through STAT1-JNK3 signalling. Nat Commun. 2015;6:6576 pubmed publisher
  • western blot; mouse; fig s1i
Van Den Ham K, Shio M, Rainone A, Fournier S, Krawczyk C, Olivier M. Iron prevents the development of experimental cerebral malaria by attenuating CXCR3-mediated T cell chemotaxis. PLoS ONE. 2015;10:e0118451 pubmed publisher
  • western blot; mouse
Vegran F, Berger H, Boidot R, Mignot G, Bruchard M, Dosset M, et al. The transcription factor IRF1 dictates the IL-21-dependent anticancer functions of TH9 cells. Nat Immunol. 2014;15:758-66 pubmed publisher
  • western blot; human
Bao Y, Cao X, Luo D, Sun R, Peng L, Wang L, et al. Urokinase-type plasminogen activator receptor signaling is critical in nasopharyngeal carcinoma cell growth and metastasis. Cell Cycle. 2014;13:1958-69 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:250
Tymoszuk P, Charoentong P, Hackl H, Spilka R, Muller Holzner E, Trajanoski Z, et al. High STAT1 mRNA levels but not its tyrosine phosphorylation are associated with macrophage infiltration and bad prognosis in breast cancer. BMC Cancer. 2014;14:257 pubmed publisher
Su C, Tseng C, Yu C, Lai M. SUMO Modification Stabilizes Dengue Virus Nonstructural Protein 5 To Support Virus Replication. J Virol. 2016;90:4308-4319 pubmed publisher
Chakraborty S, Li L, Puliyappadamba V, Guo G, Hatanpaa K, Mickey B, et al. Constitutive and ligand-induced EGFR signalling triggers distinct and mutually exclusive downstream signalling networks. Nat Commun. 2014;5:5811 pubmed publisher
Huang W, Lin C. EBV-encoded miR-BART20-5p and miR-BART8 inhibit the IFN-?-STAT1 pathway associated with disease progression in nasal NK-cell lymphoma. Am J Pathol. 2014;184:1185-97 pubmed publisher
Durrieu L, Gregoire Gauthier J, Dieng M, Fontaine F, Le Deist F, Haddad E. Human interferon-alpha increases the cytotoxic effect of CD56(+) cord blood-derived cytokine-induced killer cells on human B-acute lymphoblastic leukemia cell lines. Cytotherapy. 2012;14:1245-57 pubmed publisher
D Agostino J, Ding X, Zhang P, Jia K, Fang C, Zhu Y, et al. Potential biological functions of cytochrome P450 reductase-dependent enzymes in small intestine: novel link to expression of major histocompatibility complex class II genes. J Biol Chem. 2012;287:17777-88 pubmed publisher
Leang R, Wu T, Hwang S, Liang L, Tong L, Truong J, et al. The anti-interferon activity of conserved viral dUTPase ORF54 is essential for an effective MHV-68 infection. PLoS Pathog. 2011;7:e1002292 pubmed publisher
Shachaf C, Elchuri S, Koh A, Zhu J, Nguyen L, Mitchell D, et al. A novel method for detection of phosphorylation in single cells by surface enhanced Raman scattering (SERS) using composite organic-inorganic nanoparticles (COINs). PLoS ONE. 2009;4:e5206 pubmed publisher
product information
SKU :
9175S
Product-Name :
Stat1 (42H3) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, Mk
Applications :
Immunohistochemistry (Paraffin)
Product-Category :
Immunology and Inflammation
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
84, 91
Host :
Rabbit
Target :
Stat1
Primary-Protein :
STAT1
Alt-Names :
DKFZp686B04100,ISGF-3,STAT1,STAT91,Signal transducer and activator of transcription 1-alpha/beta,Transcription factor ISGF-3 components p91/p84,signal transducer and activator of transcription 1, 91kDa,signal transducer and activator of transcription-1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.