Published Application/Species/Dilution | Reference |
- western blot (knockout validation); human; fig 1
| Ah-Koon L, Lesage D, Lemadre E, Souissi I, Fagard R, Varin-Blank N, et al. Cellular response to alkylating agent MNNG is impaired in STAT1-deficients cells. J Cell Mol Med. 2016;20:1956-65 pubmed publisher
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- immunohistochemistry - paraffin section; human
| Southworth T, Plumb J, Gupta V, Pearson J, Ramis I, Lehner M, et al. Anti-inflammatory potential of PI3Kδ and JAK inhibitors in asthma patients. Respir Res. 2016;17:124 pubmed
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- immunohistochemistry; mouse; 1:1000; fig 1
| Senzacqua M, Severi I, Perugini J, Acciarini S, Cinti S, Giordano A. Action of Administered Ciliary Neurotrophic Factor on the Mouse Dorsal Vagal Complex. Front Neurosci. 2016;10:289 pubmed publisher
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- western blot; mouse; fig 4c
| Kim J, Weeratunga P, Kim M, Nikapitiya C, Lee B, Uddin M, et al. Inhibitory effects of an aqueous extract from Cortex Phellodendri on the growth and replication of broad-spectrum of viruses in vitro and in vivo. BMC Complement Altern Med. 2016;16:265 pubmed publisher
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- immunoprecipitation; human; fig 2
- western blot; human; 1:1000; fig 2
| Ren Y, Zhao P, Liu J, Yuan Y, Cheng Q, Zuo Y, et al. Deubiquitinase USP2a Sustains Interferons Antiviral Activity by Restricting Ubiquitination of Activated STAT1 in the Nucleus. PLoS Pathog. 2016;12:e1005764 pubmed publisher
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- western blot; human; 1:200; fig st1
| Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
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- immunohistochemistry; human; 1:50; tbl 2
| Menter T, Dickenmann M, Juskevicius D, Steiger J, Dirnhofer S, Tzankov A. Comprehensive phenotypic characterization of PTLD reveals potential reliance on EBV or NF-κB signalling instead of B-cell receptor signalling. Hematol Oncol. 2016;: pubmed publisher
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- western blot; human; 1:1000; fig 5
| Sharma N, Kumawat K, Rastogi M, Basu A, Singh S. Japanese Encephalitis Virus exploits the microRNA-432 to regulate the expression of Suppressor of Cytokine Signaling (SOCS) 5. Sci Rep. 2016;6:27685 pubmed publisher
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- western blot; mouse; fig 1a
| Anghelina D, Lam E, Falck-Pedersen E. Diminished Innate Antiviral Response to Adenovirus Vectors in cGAS/STING-Deficient Mice Minimally Impacts Adaptive Immunity. J Virol. 2016;90:5915-27 pubmed publisher
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- western blot; human; fig s1c
| Wang Z, Ji J, Peng D, Ma F, Cheng G, Qin F. Complex Regulation Pattern of IRF3 Activation Revealed by a Novel Dimerization Reporter System. J Immunol. 2016;196:4322-30 pubmed publisher
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- western blot; mouse; fig 4
| Radhakrishnan V, Kojs P, Ramalingam R, Midura-Kiela M, Angeli P, Kiela P, et al. Experimental colitis is associated with transcriptional inhibition of Na+/Ca2+ exchanger isoform 1 (NCX1) expression by interferon γ in the renal distal convoluted tubules. J Biol Chem. 2015;290:8964-74 pubmed publisher
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| Bao Y, Cao X, Luo D, Sun R, Peng L, Wang L, et al. Urokinase-type plasminogen activator receptor signaling is critical in nasopharyngeal carcinoma cell growth and metastasis. Cell Cycle. 2014;13:1958-69 pubmed publisher
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| Liu Y, Zhang Z, Zhao X, Yu R, Zhang X, Wu S, et al. Enterovirus 71 Inhibits Cellular Type I Interferon Signaling by Downregulating JAK1 Protein Expression. Viral Immunol. 2014;27:267-76 pubmed
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| McGuire D, Rowse A, Li H, Peng B, Sestero C, Cashman K, et al. CD5 enhances Th17-cell differentiation by regulating IFN-γ response and RORγt localization. Eur J Immunol. 2014;44:1137-42 pubmed publisher
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- western blot; mouse; 1:3000
| Lam E, Stein S, Falck-Pedersen E. Adenovirus detection by the cGAS/STING/TBK1 DNA sensing cascade. J Virol. 2014;88:974-81 pubmed publisher
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| Kearney S, Delgado C, Eshleman E, Hill K, O'CONNOR B, Lenz L. Type I IFNs downregulate myeloid cell IFN-γ receptor by inducing recruitment of an early growth response 3/NGFI-A binding protein 1 complex that silences ifngr1 transcription. J Immunol. 2013;191:3384-92 pubmed publisher
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- immunohistochemistry; mouse
| Syu L, El-Zaatari M, Eaton K, Liu Z, Tetarbe M, Keeley T, et al. Transgenic expression of interferon-γ in mouse stomach leads to inflammation, metaplasia, and dysplasia. Am J Pathol. 2012;181:2114-25 pubmed publisher
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- western blot; human; 1:2000
| Chen Y, Wu K, Chen C. Methamphetamine reduces human influenza A virus replication. PLoS ONE. 2012;7:e48335 pubmed publisher
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- immunohistochemistry - paraffin section; human; 1:400
- western blot; human
| Li Y, Deuring J, Peppelenbosch M, Kuipers E, de Haar C, van der Woude C. STAT1, STAT6 and adenosine 3',5'-cyclic monophosphate (cAMP) signaling drive SOCS3 expression in inactive ulcerative colitis. Mol Med. 2012;18:1412-9 pubmed publisher
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| Nishizawa K, Oguma A, Kawata M, Sakasegawa Y, Teruya K, Doh-ura K. Efficacy and mechanism of a glycoside compound inhibiting abnormal prion protein formation in prion-infected cells: implications of interferon and phosphodiesterase 4D-interacting protein. J Virol. 2014;88:4083-99 pubmed publisher
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| Cheng Z, Li-Sha G, Jing-Lin Z, Wen-Wu Z, Xue-Si C, Xing-Xing C, et al. Protective role of the cholinergic anti-inflammatory pathway in a mouse model of viral myocarditis. PLoS ONE. 2014;9:e112719 pubmed publisher
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| Datta S, Parajuli N, Tymoszuk P, Ottina E, Parson W, Sgonc R, et al. Replenishment of the B cell compartment after doxorubicin-induced hematopoietic toxicity is facilitated by STAT1. J Leukoc Biol. 2014;95:853-66 pubmed publisher
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| Lange C, Gouttenoire J, Duong F, Morikawa K, Heim M, Moradpour D. Vitamin D receptor and Jak-STAT signaling crosstalk results in calcitriol-mediated increase of hepatocellular response to IFN-α. J Immunol. 2014;192:6037-44 pubmed publisher
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| Vlková V, Stepanek I, Hruskova V, Senigl F, Mayerova V, Srámek M, et al. Epigenetic regulations in the IFNγ signalling pathway: IFNγ-mediated MHC class I upregulation on tumour cells is associated with DNA demethylation of antigen-presenting machinery genes. Oncotarget. 2014;5:6923-35 pubmed
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| Schulz A, Dürr C, Zenz T, Dohner H, Stilgenbauer S, Lichter P, et al. Lenalidomide reduces survival of chronic lymphocytic leukemia cells in primary cocultures by altering the myeloid microenvironment. Blood. 2013;121:2503-11 pubmed publisher
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| Lupberger J, Duong F, Fofana I, Zona L, Xiao F, Thumann C, et al. Epidermal growth factor receptor signaling impairs the antiviral activity of interferon-alpha. Hepatology. 2013;58:1225-35 pubmed publisher
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| Liu G, Hu X, Sun B, Yang T, Shi J, Zhang L, et al. Phosphatase Wip1 negatively regulates neutrophil development through p38 MAPK-STAT1. Blood. 2013;121:519-29 pubmed publisher
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| Schlatterer S, Suh H, Conejero-Goldberg C, Chen S, Acker C, Lee S, et al. Neuronal c-Abl activation leads to induction of cell cycle and interferon signaling pathways. J Neuroinflammation. 2012;9:208 pubmed publisher
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| Hebel K, Rudolph M, Kosak B, Chang H, Butzmann J, Brunner-Weinzierl M. IL-1β and TGF-β act antagonistically in induction and differentially in propagation of human proinflammatory precursor CD4+ T cells. J Immunol. 2011;187:5627-35 pubmed publisher
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| Weigert O, Lane A, Bird L, Kopp N, Chapuy B, Van Bodegom D, et al. Genetic resistance to JAK2 enzymatic inhibitors is overcome by HSP90 inhibition. J Exp Med. 2012;209:259-73 pubmed publisher
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| Boaru S, Borkham-Kamphorst E, Tihaa L, Haas U, Weiskirchen R. Expression analysis of inflammasomes in experimental models of inflammatory and fibrotic liver disease. J Inflamm (Lond). 2012;9:49 pubmed publisher
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| Durrieu L, Gregoire-Gauthier J, Dieng M, Fontaine F, Le Deist F, Haddad E. Human interferon-alpha increases the cytotoxic effect of CD56(+) cord blood-derived cytokine-induced killer cells on human B-acute lymphoblastic leukemia cell lines. Cytotherapy. 2012;14:1245-57 pubmed publisher
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| Morandi F, Prigione I, Airoldi I. Human TCRγδ+ T cells represent a novel target for IL-27 activity. Eur J Immunol. 2012;42:1547-52 pubmed publisher
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| Zorzoli A, Di Carlo E, Cocco C, Ognio E, Ribatti D, Ferretti E, et al. Interleukin-27 inhibits the growth of pediatric acute myeloid leukemia in NOD/SCID/Il2rg-/- mice. Clin Cancer Res. 2012;18:1630-40 pubmed publisher
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