product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-Stat1 (Tyr701) (58D6) Rabbit mAb
catalog :
9167S
quantity :
100 ul
price :
274 USD
clonality :
monoclonal
host :
rabbit
antigen modification :
phosphorylated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation, immunohistochemistry - paraffin section
citations: 34
Published Application/Species/DilutionReference
  • western blot (knockout validation); human; fig 1
Ah-Koon L, Lesage D, Lemadre E, Souissi I, Fagard R, Varin-Blank N, et al. Cellular response to alkylating agent MNNG is impaired in STAT1-deficients cells. J Cell Mol Med. 2016;20:1956-65 pubmed publisher
  • immunohistochemistry - paraffin section; human
Southworth T, Plumb J, Gupta V, Pearson J, Ramis I, Lehner M, et al. Anti-inflammatory potential of PI3Kδ and JAK inhibitors in asthma patients. Respir Res. 2016;17:124 pubmed
  • immunohistochemistry; mouse; 1:1000; fig 1
Senzacqua M, Severi I, Perugini J, Acciarini S, Cinti S, Giordano A. Action of Administered Ciliary Neurotrophic Factor on the Mouse Dorsal Vagal Complex. Front Neurosci. 2016;10:289 pubmed publisher
  • western blot; mouse; fig 4c
Kim J, Weeratunga P, Kim M, Nikapitiya C, Lee B, Uddin M, et al. Inhibitory effects of an aqueous extract from Cortex Phellodendri on the growth and replication of broad-spectrum of viruses in vitro and in vivo. BMC Complement Altern Med. 2016;16:265 pubmed publisher
  • immunoprecipitation; human; fig 2
  • western blot; human; 1:1000; fig 2
Ren Y, Zhao P, Liu J, Yuan Y, Cheng Q, Zuo Y, et al. Deubiquitinase USP2a Sustains Interferons Antiviral Activity by Restricting Ubiquitination of Activated STAT1 in the Nucleus. PLoS Pathog. 2016;12:e1005764 pubmed publisher
  • western blot; human; 1:200; fig st1
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  • immunohistochemistry; human; 1:50; tbl 2
Menter T, Dickenmann M, Juskevicius D, Steiger J, Dirnhofer S, Tzankov A. Comprehensive phenotypic characterization of PTLD reveals potential reliance on EBV or NF-κB signalling instead of B-cell receptor signalling. Hematol Oncol. 2016;: pubmed publisher
  • western blot; human; 1:1000; fig 5
Sharma N, Kumawat K, Rastogi M, Basu A, Singh S. Japanese Encephalitis Virus exploits the microRNA-432 to regulate the expression of Suppressor of Cytokine Signaling (SOCS) 5. Sci Rep. 2016;6:27685 pubmed publisher
  • western blot; mouse; fig 1a
Anghelina D, Lam E, Falck-Pedersen E. Diminished Innate Antiviral Response to Adenovirus Vectors in cGAS/STING-Deficient Mice Minimally Impacts Adaptive Immunity. J Virol. 2016;90:5915-27 pubmed publisher
  • western blot; human; fig s1c
Wang Z, Ji J, Peng D, Ma F, Cheng G, Qin F. Complex Regulation Pattern of IRF3 Activation Revealed by a Novel Dimerization Reporter System. J Immunol. 2016;196:4322-30 pubmed publisher
  • western blot; mouse; fig 4
Radhakrishnan V, Kojs P, Ramalingam R, Midura-Kiela M, Angeli P, Kiela P, et al. Experimental colitis is associated with transcriptional inhibition of Na+/Ca2+ exchanger isoform 1 (NCX1) expression by interferon γ in the renal distal convoluted tubules. J Biol Chem. 2015;290:8964-74 pubmed publisher
  • western blot; human
Bao Y, Cao X, Luo D, Sun R, Peng L, Wang L, et al. Urokinase-type plasminogen activator receptor signaling is critical in nasopharyngeal carcinoma cell growth and metastasis. Cell Cycle. 2014;13:1958-69 pubmed publisher
  • western blot; human
Liu Y, Zhang Z, Zhao X, Yu R, Zhang X, Wu S, et al. Enterovirus 71 Inhibits Cellular Type I Interferon Signaling by Downregulating JAK1 Protein Expression. Viral Immunol. 2014;27:267-76 pubmed
  • flow cytometry; mouse
McGuire D, Rowse A, Li H, Peng B, Sestero C, Cashman K, et al. CD5 enhances Th17-cell differentiation by regulating IFN-γ response and RORγt localization. Eur J Immunol. 2014;44:1137-42 pubmed publisher
  • western blot; mouse; 1:3000
Lam E, Stein S, Falck-Pedersen E. Adenovirus detection by the cGAS/STING/TBK1 DNA sensing cascade. J Virol. 2014;88:974-81 pubmed publisher
  • western blot; mouse
Kearney S, Delgado C, Eshleman E, Hill K, O'CONNOR B, Lenz L. Type I IFNs downregulate myeloid cell IFN-γ receptor by inducing recruitment of an early growth response 3/NGFI-A binding protein 1 complex that silences ifngr1 transcription. J Immunol. 2013;191:3384-92 pubmed publisher
  • immunohistochemistry; mouse
Syu L, El-Zaatari M, Eaton K, Liu Z, Tetarbe M, Keeley T, et al. Transgenic expression of interferon-γ in mouse stomach leads to inflammation, metaplasia, and dysplasia. Am J Pathol. 2012;181:2114-25 pubmed publisher
  • western blot; human; 1:2000
Chen Y, Wu K, Chen C. Methamphetamine reduces human influenza A virus replication. PLoS ONE. 2012;7:e48335 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:400
  • western blot; human
Li Y, Deuring J, Peppelenbosch M, Kuipers E, de Haar C, van der Woude C. STAT1, STAT6 and adenosine 3',5'-cyclic monophosphate (cAMP) signaling drive SOCS3 expression in inactive ulcerative colitis. Mol Med. 2012;18:1412-9 pubmed publisher
Nishizawa K, Oguma A, Kawata M, Sakasegawa Y, Teruya K, Doh-ura K. Efficacy and mechanism of a glycoside compound inhibiting abnormal prion protein formation in prion-infected cells: implications of interferon and phosphodiesterase 4D-interacting protein. J Virol. 2014;88:4083-99 pubmed publisher
Cheng Z, Li-Sha G, Jing-Lin Z, Wen-Wu Z, Xue-Si C, Xing-Xing C, et al. Protective role of the cholinergic anti-inflammatory pathway in a mouse model of viral myocarditis. PLoS ONE. 2014;9:e112719 pubmed publisher
Datta S, Parajuli N, Tymoszuk P, Ottina E, Parson W, Sgonc R, et al. Replenishment of the B cell compartment after doxorubicin-induced hematopoietic toxicity is facilitated by STAT1. J Leukoc Biol. 2014;95:853-66 pubmed publisher
Lange C, Gouttenoire J, Duong F, Morikawa K, Heim M, Moradpour D. Vitamin D receptor and Jak-STAT signaling crosstalk results in calcitriol-mediated increase of hepatocellular response to IFN-α. J Immunol. 2014;192:6037-44 pubmed publisher
Vlková V, Stepanek I, Hruskova V, Senigl F, Mayerova V, Srámek M, et al. Epigenetic regulations in the IFNγ signalling pathway: IFNγ-mediated MHC class I upregulation on tumour cells is associated with DNA demethylation of antigen-presenting machinery genes. Oncotarget. 2014;5:6923-35 pubmed
Schulz A, Dürr C, Zenz T, Dohner H, Stilgenbauer S, Lichter P, et al. Lenalidomide reduces survival of chronic lymphocytic leukemia cells in primary cocultures by altering the myeloid microenvironment. Blood. 2013;121:2503-11 pubmed publisher
Lupberger J, Duong F, Fofana I, Zona L, Xiao F, Thumann C, et al. Epidermal growth factor receptor signaling impairs the antiviral activity of interferon-alpha. Hepatology. 2013;58:1225-35 pubmed publisher
Liu G, Hu X, Sun B, Yang T, Shi J, Zhang L, et al. Phosphatase Wip1 negatively regulates neutrophil development through p38 MAPK-STAT1. Blood. 2013;121:519-29 pubmed publisher
Schlatterer S, Suh H, Conejero-Goldberg C, Chen S, Acker C, Lee S, et al. Neuronal c-Abl activation leads to induction of cell cycle and interferon signaling pathways. J Neuroinflammation. 2012;9:208 pubmed publisher
Hebel K, Rudolph M, Kosak B, Chang H, Butzmann J, Brunner-Weinzierl M. IL-1β and TGF-β act antagonistically in induction and differentially in propagation of human proinflammatory precursor CD4+ T cells. J Immunol. 2011;187:5627-35 pubmed publisher
Weigert O, Lane A, Bird L, Kopp N, Chapuy B, Van Bodegom D, et al. Genetic resistance to JAK2 enzymatic inhibitors is overcome by HSP90 inhibition. J Exp Med. 2012;209:259-73 pubmed publisher
Boaru S, Borkham-Kamphorst E, Tihaa L, Haas U, Weiskirchen R. Expression analysis of inflammasomes in experimental models of inflammatory and fibrotic liver disease. J Inflamm (Lond). 2012;9:49 pubmed publisher
Durrieu L, Gregoire-Gauthier J, Dieng M, Fontaine F, Le Deist F, Haddad E. Human interferon-alpha increases the cytotoxic effect of CD56(+) cord blood-derived cytokine-induced killer cells on human B-acute lymphoblastic leukemia cell lines. Cytotherapy. 2012;14:1245-57 pubmed publisher
Morandi F, Prigione I, Airoldi I. Human TCRγδ+ T cells represent a novel target for IL-27 activity. Eur J Immunol. 2012;42:1547-52 pubmed publisher
Zorzoli A, Di Carlo E, Cocco C, Ognio E, Ribatti D, Ferretti E, et al. Interleukin-27 inhibits the growth of pediatric acute myeloid leukemia in NOD/SCID/Il2rg-/- mice. Clin Cancer Res. 2012;18:1630-40 pubmed publisher
product information
SKU :
9167S
Product-Name :
Phospho-Stat1 (Tyr701) (58D6) Rabbit mAb
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M
Applications :
Chromatin Immunoprecipitation
Product-Category :
Immunology and Inflammation
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
84, 91
Host :
Rabbit
Target :
Stat1 (Tyr701) phosphate
Primary-Protein :
STAT1
Alt-Names :
DKFZp686B04100,ISGF-3,STAT1,STAT91,Signal transducer and activator of transcription 1-alpha/beta,Transcription factor ISGF-3 components p91/p84,signal transducer and activator of transcription 1, 91kDa,signal transducer and activator of transcription-1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.