product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
LAT Antibody
catalog :
9166
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 17
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; 1:25; loading ...; fig 3g
  • western blot; mouse; loading ...; fig 3e
Naik E, Dixit V. Usp9X Is Required for Lymphocyte Activation and Homeostasis through Its Control of ZAP70 Ubiquitination and PKCβ Kinase Activity. J Immunol. 2016;196:3438-51 pubmed publisher
  • western blot; human
Ebsen H, Lettau M, Kabelitz D, Janssen O. Subcellular localization and activation of ADAM proteases in the context of FasL shedding in T lymphocytes. Mol Immunol. 2015;65:416-28 pubmed publisher
Kapoor Kaushik N, Hinde E, Compeer E, Yamamoto Y, Kraus F, Yang Z, et al. Distinct Mechanisms Regulate Lck Spatial Organization in Activated T Cells. Front Immunol. 2016;7:83 pubmed publisher
Kailainathan S, Piers T, Yi J, Choi S, Fahey M, Borger E, et al. Activation of a synapse weakening pathway by human Val66 but not Met66 pro-brain-derived neurotrophic factor (proBDNF). Pharmacol Res. 2016;104:97-107 pubmed publisher
Vétillard A, Jonchère B, Moreau M, Toutain B, Henry C, Fontanel S, et al. Akt inhibition improves irinotecan treatment and prevents cell emergence by switching the senescence response to apoptosis. Oncotarget. 2015;6:43342-62 pubmed publisher
Conde Perez A, Gros G, Longvert C, Pedersen M, Petit V, Aktary Z, et al. A caveolin-dependent and PI3K/AKT-independent role of PTEN in β-catenin transcriptional activity. Nat Commun. 2015;6:8093 pubmed publisher
Devi L, Ohno M. TrkB reduction exacerbates Alzheimer's disease-like signaling aberrations and memory deficits without affecting β-amyloidosis in 5XFAD mice. Transl Psychiatry. 2015;5:e562 pubmed publisher
Zhang B, Zhang T, Wang G, Wang G, Chi W, Jiang Q, et al. GSK3β-Dzip1-Rab8 cascade regulates ciliogenesis after mitosis. PLoS Biol. 2015;13:e1002129 pubmed publisher
Markwart R, Condotta S, Requardt R, Borken F, Schubert K, Weigel C, et al. Immunosuppression after sepsis: systemic inflammation and sepsis induce a loss of naïve T-cells but no enduring cell-autonomous defects in T-cell function. PLoS ONE. 2014;9:e115094 pubmed publisher
Forsdahl S, Kiselev Y, Hogseth R, Mjelle J, Mikkola I. Pax6 regulates the expression of Dkk3 in murine and human cell lines, and altered responses to Wnt signaling are shown in FlpIn-3T3 cells stably expressing either the Pax6 or the Pax6(5a) isoform. PLoS ONE. 2014;9:e102559 pubmed publisher
Okada T, Nitta T, Kaji K, Takashima A, Oda H, Tamehiro N, et al. Differential function of Themis CABIT domains during T cell development. PLoS ONE. 2014;9:e89115 pubmed publisher
Tan Y, Manz B, Freedman T, Zhang C, Shokat K, Weiss A. Inhibition of the kinase Csk in thymocytes reveals a requirement for actin remodeling in the initiation of full TCR signaling. Nat Immunol. 2014;15:186-94 pubmed publisher
Ito N, Ruegg U, Kudo A, Miyagoe Suzuki Y, Takeda S. Capsaicin mimics mechanical load-induced intracellular signaling events: involvement of TRPV1-mediated calcium signaling in induction of skeletal muscle hypertrophy. Channels (Austin). 2013;7:221-4 pubmed publisher
Lee J, Jiffar T, Kupferman M. A novel role for BDNF-TrkB in the regulation of chemotherapy resistance in head and neck squamous cell carcinoma. PLoS ONE. 2012;7:e30246 pubmed publisher
Liu J, Ding X, Tang J, Cao Y, Hu P, Zhou F, et al. Enhancement of canonical Wnt/?-catenin signaling activity by HCV core protein promotes cell growth of hepatocellular carcinoma cells. PLoS ONE. 2011;6:e27496 pubmed publisher
Verhagen A, de Graaf C, Baldwin T, Goradia A, Collinge J, Kile B, et al. Reduced lymphocyte longevity and homeostatic proliferation in lamin B receptor-deficient mice results in profound and progressive lymphopenia. J Immunol. 2012;188:122-34 pubmed publisher
Harr M, Caimi P, McColl K, Zhong F, Patel S, Barr P, et al. Inhibition of Lck enhances glucocorticoid sensitivity and apoptosis in lymphoid cell lines and in chronic lymphocytic leukemia. Cell Death Differ. 2010;17:1381-91 pubmed publisher
product information
SKU :
9166P
Product-Name :
LAT Antibody
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H, M, (R)
Applications :
Flow cytometry
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
36, 38
Host :
Rabbit
Target :
LAT
Primary-Protein :
LAT
Alt-Names :
36 kDa phospho-tyrosine adapter protein,36 kDa phospho-tyrosine adaptor protein,LAT,LAT1,Linker for activation of T-cells family member 1,linker for activation of T cells,p36-38,pp36
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.