product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
c-Jun (60A8) Rabbit mAb
catalog :
9165L
quantity :
300 ul
price :
574 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 28
Published Application/Species/DilutionReference
  • western blot; mouse; 1:1000; fig 5
  • immunocytochemistry; mouse; 1:100; fig 5
Liu J, Han Q, Peng T, Peng M, Wei B, Li D, et al. The oncogene c-Jun impedes somatic cell reprogramming. Nat Cell Biol. 2015;17:856-67 pubmed publisher
  • western blot; mouse
Krokowski D, Jobava R, Guan B, Farabaugh K, Wu J, Majumder M, et al. Coordinated Regulation of the Neutral Amino Acid Transporter SNAT2 and the Protein Phosphatase Subunit GADD34 Promotes Adaptation to Increased Extracellular Osmolarity. J Biol Chem. 2015;290:17822-37 pubmed publisher
  • western blot; mouse; 1:500
He J, Quintana M, Sullivan J, L Parry T, J Grevengoed T, Schisler J, et al. MuRF2 regulates PPARγ1 activity to protect against diabetic cardiomyopathy and enhance weight gain induced by a high fat diet. Cardiovasc Diabetol. 2015;14:97 pubmed publisher
  • western blot; mouse; fig 4b
Lebrun-Julien F, Suter U. Combined HDAC1 and HDAC2 Depletion Promotes Retinal Ganglion Cell Survival After Injury Through Reduction of p53 Target Gene Expression. ASN Neuro. 2015;7: pubmed publisher
  • western blot; mouse; 1:1000; fig 2e
Feuerborn A, Mathow D, Srivastava P, Gretz N, Grone H. Basonuclin-1 modulates epithelial plasticity and TGF-β1-induced loss of epithelial cell integrity. Oncogene. 2015;34:1185-95 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:100
Hollis E, Ishiko N, Tolentino K, Doherty E, Rodríguez M, Calcutt N, et al. A novel and robust conditioning lesion induced by ethidium bromide. Exp Neurol. 2015;265:30-9 pubmed publisher
  • western blot; mouse; 1:500
Quintana M, He J, Sullivan J, Grevengoed T, Schisler J, Han Y, et al. Muscle ring finger-3 protects against diabetic cardiomyopathy induced by a high fat diet. BMC Endocr Disord. 2015;15:36 pubmed publisher
  • western blot; human
Parseghian S, Onstead-Haas L, Wong N, Mooradian A, Haas M. Inhibition of apolipoprotein A-I expression by TNF-alpha in HepG2 cells: requirement for c-jun. J Cell Biochem. 2014;115:253-60 pubmed publisher
  • western blot; human
Lu G, Zhang Q, Huang Y, Song J, Tomaino R, Ehrenberger T, et al. Phosphorylation of ETS1 by Src family kinases prevents its recognition by the COP1 tumor suppressor. Cancer Cell. 2014;26:222-34 pubmed publisher
  • western blot; human
Bartling T, Subbaram S, Clark R, Chandrasekaran A, Kar S, Melendez J. Redox-sensitive gene-regulatory events controlling aberrant matrix metalloproteinase-1 expression. Free Radic Biol Med. 2014;74:99-107 pubmed publisher
  • western blot; mouse; 1:500; fig 3, 5
Wadosky K, Rodriguez J, Hite R, Min J, Walton B, Willis M. Muscle RING finger-1 attenuates IGF-I-dependent cardiomyocyte hypertrophy by inhibiting JNK signaling. Am J Physiol Endocrinol Metab. 2014;306:E723-39 pubmed publisher
  • western blot; mouse; fig 1
Romanov V, Brichkina A, Morrison H, Pospelova T, Pospelov V, Herrlich P. Novel mechanism of JNK pathway activation by adenoviral E1A. Oncotarget. 2014;5:2176-86 pubmed
Mojsa B, Mora S, Bossowski J, Lassot I, Desagher S. Control of neuronal apoptosis by reciprocal regulation of NFATc3 and Trim17. Cell Death Differ. 2015;22:274-86 pubmed publisher
Paul T, Schumann C, Rudiger S, Boeck S, Heinemann V, Kächele V, et al. Cytokine regulation by epidermal growth factor receptor inhibitors and epidermal growth factor receptor inhibitor associated skin toxicity in cancer patients. Eur J Cancer. 2014;50:1855-63 pubmed publisher
Berghoff A, Birner P, Streubel B, Kenner L, Preusser M. ALK gene aberrations and the JUN/JUNB/PDGFR axis in metastatic NSCLC. APMIS. 2014;122:867-72 pubmed publisher
Katsuyama M, Ibi M, Matsumoto M, Iwata K, Ohshima Y, Yabe-Nishimura C. Clioquinol increases the expression of VGF, a neuropeptide precursor, through induction of c-Fos expression. J Pharmacol Sci. 2014;124:427-32 pubmed
Shiheido H, Aoyama T, Takahashi H, Hanaoka K, Abe T, Nishida E, et al. Novel CD3-specific antibody induces immunosuppression via impaired phosphorylation of LAT and PLCγ1 following T-cell stimulation. Eur J Immunol. 2014;44:1770-80 pubmed publisher
Björkblom B, Maple-Grødem J, Puno M, Odell M, Larsen J, Møller S. Reactive oxygen species-mediated DJ-1 monomerization modulates intracellular trafficking involving karyopherin β2. Mol Cell Biol. 2014;34:3024-40 pubmed publisher
Tomé M, Sepúlveda J, Delgado M, Andrades J, Campisi J, Gonzalez M, et al. miR-335 correlates with senescence/aging in human mesenchymal stem cells and inhibits their therapeutic actions through inhibition of AP-1 activity. Stem Cells. 2014;32:2229-44 pubmed publisher
Szmydynger-Chodobska J, Gandy J, Varone A, Shan R, Chodobski A. Synergistic interactions between cytokines and AVP at the blood-CSF barrier result in increased chemokine production and augmented influx of leukocytes after brain injury. PLoS ONE. 2013;8:e79328 pubmed publisher
Zou T, Yang Y, Xia F, Huang A, Gao X, Fang D, et al. Resveratrol Inhibits CD4+ T cell activation by enhancing the expression and activity of Sirt1. PLoS ONE. 2013;8:e75139 pubmed publisher
Lan R, Geng H, Polichnowski A, Singha P, Saikumar P, McEwen D, et al. PTEN loss defines a TGF-β-induced tubule phenotype of failed differentiation and JNK signaling during renal fibrosis. Am J Physiol Renal Physiol. 2012;302:F1210-23 pubmed publisher
Ono Y, Hayashida T, Konagai A, Okazaki H, Miyao K, Kawachi S, et al. Direct inhibition of the transforming growth factor-β pathway by protein-bound polysaccharide through inactivation of Smad2 signaling. Cancer Sci. 2012;103:317-24 pubmed publisher
Tokunaga F, Sakata S, Saeki Y, Satomi Y, Kirisako T, Kamei K, et al. Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation. Nat Cell Biol. 2009;11:123-32 pubmed publisher
Wang Q, Na B, Ou J, Pulliam L, Yen T. Hepatitis B virus alters the antioxidant system in transgenic mice and sensitizes hepatocytes to Fas signaling. PLoS ONE. 2012;7:e36818 pubmed publisher
Ouyang J, Juszczynski P, Rodig S, Green M, O'Donnell E, Currie T, et al. Viral induction and targeted inhibition of galectin-1 in EBV+ posttransplant lymphoproliferative disorders. Blood. 2011;117:4315-22 pubmed publisher
Kim M, Ju J, Jang K, Oh S, Song J, Kim C, et al. Protein kinase Cδ negatively regulates Notch1-dependent transcription via a kinase-independent mechanism in vitro. Biochim Biophys Acta. 2012;1823:387-97 pubmed publisher
Xu B, Chen H, Xu W, Zhang W, Buckley S, Zheng S, et al. Molecular mechanisms of MMP9 overexpression and its role in emphysema pathogenesis of Smad3-deficient mice. Am J Physiol Lung Cell Mol Physiol. 2012;303:L89-96 pubmed publisher
product information
SKU :
9165L
Product-Name :
c-Jun (60A8) Rabbit mAb
Size :
300 ul
Price-(USD) :
574 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Chromatin Immunoprecipitation
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
43, 48
Host :
Rabbit
Target :
JUN
Primary-Protein :
Jun
Alt-Names :
AP-1,AP1,Activator protein 1,JUN,Jun activation domain binding protein,Proto-oncogene c-Jun,Transcription factor AP-1,V-jun avian sarcoma virus 17 oncogene homolog,c-Jun,enhancer-binding protein AP1,jun oncogene,p39,v-jun sarcoma virus 17 oncogene homolog
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.