product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
c-Jun (60A8) Rabbit mAb
catalog :
9165
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
60A8
reactivity :
Leishmania , human, mouse, rat, dogs
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, reverse phase protein lysate microarray, other, western blot knockout validation
citations: 170
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; fig 4
Liu X, Li H, Rajurkar M, Li Q, Cotton J, Ou J, et al. Tead and AP1 Coordinate Transcription and Motility. Cell Rep. 2016;14:1169-1180 pubmed publisher
  • chromatin immunoprecipitation; mouse; fig 6l
  • western blot; mouse; fig s11c
  • chromatin immunoprecipitation; human; fig 6k
  • western blot; human; fig s11c
Wang Z, He L, Li W, Xu C, Zhang J, Wang D, et al. GDF15 induces immunosuppression via CD48 on regulatory T cells in hepatocellular carcinoma. J Immunother Cancer. 2021;9: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4a
Tan X, Tong L, Li L, Xu J, Xie S, Ji L, et al. Loss of Smad4 promotes aggressive lung cancer metastasis by de-repression of PAK3 via miRNA regulation. Nat Commun. 2021;12:4853 pubmed publisher
  • western blot; human; loading ...; fig 1c
Chen H, Padia R, Li T, Li Y, Li B, Jin L, et al. Signaling of MK2 sustains robust AP1 activity for triple negative breast cancer tumorigenesis through direct phosphorylation of JAB1. NPJ Breast Cancer. 2021;7:91 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 6a, 7e
Wu X, Shu L, Zhang Z, Li J, Zong J, Cheong L, et al. Adipocyte Fatty Acid Binding Protein Promotes the Onset and Progression of Liver Fibrosis via Mediating the Crosstalk between Liver Sinusoidal Endothelial Cells and Hepatic Stellate Cells. Adv Sci (Weinh). 2021;8:e2003721 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3g, 3h
Zhu X, Chen L, Huang B, Li X, Yang L, Hu X, et al. Efficacy and mechanism of the combination of PARP and CDK4/6 inhibitors in the treatment of triple-negative breast cancer. J Exp Clin Cancer Res. 2021;40:122 pubmed publisher
  • other; human; 1:25; fig 4d
Orlando K, Douglas A, Abudu A, Wang Y, Tessier Cloutier B, Su W, et al. Re-expression of SMARCA4/BRG1 in small cell carcinoma of ovary, hypercalcemic type (SCCOHT) promotes an epithelial-like gene signature through an AP-1-dependent mechanism. elife. 2020;9: pubmed publisher
  • western blot; human; loading ...; fig 4a
Karnan S, Ota A, Murakami H, Rahman M, Hasan M, Wahiduzzaman M, et al. Identification of CD24 as a potential diagnostic and therapeutic target for malignant pleural mesothelioma. Cell Death Discov. 2020;6:127 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 3a
Crespo M, González Terán B, Nikolic I, Mora A, Folgueira C, Rodriguez E, et al. Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism. elife. 2020;9: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 7a
Sinha N, Ordureau A, Best K, Saba J, Zinshteyn B, Sundaramoorthy E, et al. EDF1 coordinates cellular responses to ribosome collisions. elife. 2020;9: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4s1a
Grove M, Lee H, Zhao H, Son Y. Axon-dependent expression of YAP/TAZ mediates Schwann cell remyelination but not proliferation after nerve injury. elife. 2020;9: pubmed publisher
  • western blot; human; loading ...; fig 2i
Simula L, Corrado M, Accordi B, Di Rita A, Nazio F, Antonucci Y, et al. JNK1 and ERK1/2 modulate lymphocyte homeostasis via BIM and DRP1 upon AICD induction. Cell Death Differ. 2020;: pubmed publisher
  • immunocytochemistry; human; 1:400; loading ...; fig 7b
  • western blot; human; 1:500; loading ...; fig 7a
Bogucka K, Pompaiah M, Marini F, Binder H, Harms G, Kaulich M, et al. ERK3/MAPK6 controls IL-8 production and chemotaxis. elife. 2020;9: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:70; loading ...; fig 6b
  • western blot; mouse; 1:1000; loading ...; fig 6k
Tang Y, Xu A, Shao S, Zhou Y, Xiong B, Li Z. Electroacupuncture Ameliorates Cognitive Impairment by Inhibiting the JNK Signaling Pathway in a Mouse Model of Alzheimer's Disease. Front Aging Neurosci. 2020;12:23 pubmed publisher
  • western blot; dogs; 1:2000; loading ...; fig 3b
Wu Q, Li G, Wen C, Zeng T, Fan Y, Liu C, et al. Monoubiquitination of p120-catenin is essential for TGFβ-induced epithelial-mesenchymal transition and tumor metastasis. Sci Adv. 2020;6:eaay9819 pubmed publisher
  • western blot; human; fig 2d
Lynn R, Weber E, Sotillo E, Gennert D, Xu P, Good Z, et al. c-Jun overexpression in CAR T cells induces exhaustion resistance. Nature. 2019;576:293-300 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2a
Liu Y, Jiang Q, Liu X, Lin X, Tang Z, Liu C, et al. Cinobufotalin powerfully reversed EBV-miR-BART22-induced cisplatin resistance via stimulating MAP2K4 to antagonize non-muscle myosin heavy chain IIA/glycogen synthase 3β/β-catenin signaling pathway. EBioMedicine. 2019;48:386-404 pubmed publisher
  • western blot; human; loading ...; fig 3d
Jiang S, Zhang M, Zhang Y, Zhou W, Zhu T, Ruan Q, et al. WNT5B governs the phenotype of basal-like breast cancer by activating WNT signaling. Cell Commun Signal. 2019;17:109 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4a
Xiao W, Wang L, Howard J, Kolhe R, Rojiani A, Rojiani M. TIMP-1-Mediated Chemoresistance via Induction of IL-6 in NSCLC. Cancers (Basel). 2019;11: pubmed publisher
  • western blot; mouse; loading ...; fig 2i
Solis A, Bielecki P, Steach H, Sharma L, Harman C, Yun S, et al. Mechanosensation of cyclical force by PIEZO1 is essential for innate immunity. Nature. 2019;573:69-74 pubmed publisher
  • western blot; human; loading ...; fig 4h
Li Q, Lai Q, He C, Fang Y, Yan Q, Zhang Y, et al. RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling pathway and EMT in colorectal cancer. J Exp Clin Cancer Res. 2019;38:334 pubmed publisher
  • western blot; mouse; 1:5000; loading ...; fig 1a
  • western blot; human; 1:2000; loading ...; fig 5d
Rizzini L, Levine D, Perelis M, Bass J, Peek C, Pagano M. Cryptochromes-Mediated Inhibition of the CRL4Cop1-Complex Assembly Defines an Evolutionary Conserved Signaling Mechanism. Curr Biol. 2019;29:1954-1962.e4 pubmed publisher
  • western blot; human; loading ...; fig 6b
Guo M, Hartlova A, Gierlinski M, Prescott A, Castellvi J, Losa J, et al. Triggering MSR1 promotes JNK-mediated inflammation in IL-4-activated macrophages. EMBO J. 2019;38: pubmed publisher
  • western blot; human; fig 5i
Park H, Chung K, An H, Gim J, Hong J, Woo H, et al. Parkin Promotes Mitophagic Cell Death in Adult Hippocampal Neural Stem Cells Following Insulin Withdrawal. Front Mol Neurosci. 2019;12:46 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4b
Dong H, Ye X, Zhong L, Xu J, Qiu J, Wang J, et al. Role of FOXO3 Activated by HIV-1 Tat in HIV-Associated Neurocognitive Disorder Neuronal Apoptosis. Front Neurosci. 2019;13:44 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 1e
  • immunohistochemistry - paraffin section; human; loading ...; fig 1a
Schulien I, Hockenjos B, Schmitt Graeff A, Perdekamp M, Follo M, Thimme R, et al. The transcription factor c-Jun/AP-1 promotes liver fibrosis during non-alcoholic steatohepatitis by regulating Osteopontin expression. Cell Death Differ. 2019;: pubmed publisher
  • western blot; mouse; loading ...; fig 1h
Carugo A, Minelli R, Sapio L, Soeung M, Carbone F, Robinson F, et al. p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors. Cancer Cell. 2019;35:204-220.e9 pubmed publisher
  • western blot; mouse; loading ...; fig 3c
Xie C, Zhu J, Wang X, Chen J, Geng S, Wu J, et al. Tobacco smoke induced hepatic cancer stem cell-like properties through IL-33/p38 pathway. J Exp Clin Cancer Res. 2019;38:39 pubmed publisher
  • western blot; human; loading ...; fig 4c
Li Z, Mbah N, Overmeyer J, Sarver J, George S, Trabbic C, et al. The JNK signaling pathway plays a key role in methuosis (non-apoptotic cell death) induced by MOMIPP in glioblastoma. BMC Cancer. 2019;19:77 pubmed publisher
  • western blot; mouse; 1:1000; loading ...
Gerber D, Ghidinelli M, Tinelli E, Somandin C, Gerber J, Pereira J, et al. Schwann cells, but not Oligodendrocytes, Depend Strictly on Dynamin 2 Function. elife. 2019;8: pubmed publisher
  • western blot; human; loading ...; fig 5b
Idris M, Butcher N, Minchin R. The MBNL/CELF Splicing Factors Regulate Cytosolic Sulfotransferase 4A1 Protein Expression during Cell Differentiation. Drug Metab Dispos. 2019;47:314-319 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4c
Alam M, Yang D, Trivett A, Meyer T, Oppenheim J. HMGN1 and R848 Synergistically Activate Dendritic Cells Using Multiple Signaling Pathways. Front Immunol. 2018;9:2982 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig s11c
Bugaj L, Sabnis A, Mitchell A, Garbarino J, Toettcher J, Bivona T, et al. Cancer mutations and targeted drugs can disrupt dynamic signal encoding by the Ras-Erk pathway. Science. 2018;361: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2a
Cuchet Lourenço D, Eletto D, Wu C, Plagnol V, Papapietro O, CURTIS J, et al. Biallelic RIPK1 mutations in humans cause severe immunodeficiency, arthritis, and intestinal inflammation. Science. 2018;361:810-813 pubmed publisher
  • western blot; human; loading ...; fig 4d
Yang M, Li C, Zhu S, Cao L, Kroemer G, Zeh H, et al. TFAM is a novel mediator of immunogenic cancer cell death. Oncoimmunology. 2018;7:e1431086 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 1c
Rizzi C, Tiberi A, Giustizieri M, Marrone M, Gobbo F, Carucci N, et al. NGF steers microglia toward a neuroprotective phenotype. Glia. 2018;66:1395-1416 pubmed publisher
  • western blot; human; 1:1000; fig s2m
Bajikar S, Wang C, Borten M, Pereira E, Atkins K, Janes K. Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer. Dev Cell. 2017;43:418-435.e13 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 15a
Smith R, Huang Y, Tian T, Vojtasova D, Mesalles Naranjo O, Pollard S, et al. The Transcription Factor Foxg1 Promotes Optic Fissure Closure in the Mouse by Suppressing Wnt8b in the Nasal Optic Stalk. J Neurosci. 2017;37:7975-7993 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 6a
Aroor A, Habibi J, Kandikattu H, Garro Kacher M, Barron B, Chen D, et al. Dipeptidyl peptidase-4 (DPP-4) inhibition with linagliptin reduces western diet-induced myocardial TRAF3IP2 expression, inflammation and fibrosis in female mice. Cardiovasc Diabetol. 2017;16:61 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; loading ...; fig s6c
Ge Y, Gomez N, Adam R, Nikolova M, Yang H, Verma A, et al. Stem Cell Lineage Infidelity Drives Wound Repair and Cancer. Cell. 2017;169:636-650.e14 pubmed publisher
  • western blot; human; loading ...; fig 7a
Lafont E, Kantari Mimoun C, Dráber P, De Miguel D, Hartwig T, Reichert M, et al. The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death. EMBO J. 2017;36:1147-1166 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2c
Vallejo A, Perurena N, Guruceaga E, Mazur P, Martínez Canarias S, Zandueta C, et al. An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer. Nat Commun. 2017;8:14294 pubmed publisher
  • immunocytochemistry; rat; 1:500; loading ...; fig 5b
König H, Schwamborn R, Andresen S, Kinsella S, Watters O, Fenner B, et al. NF-κB regulates neuronal ankyrin-G via a negative feedback loop. Sci Rep. 2017;7:42006 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig s5g
  • immunohistochemistry; mouse; loading ...; fig s8i
  • western blot; mouse; loading ...; fig s8e
Genovese G, Carugo A, TEPPER J, Robinson F, Li L, Svelto M, et al. Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer. Nature. 2017;542:362-366 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200
  • western blot; mouse; 1:1000; fig 6c
Mindos T, Dun X, North K, Doddrell R, Schulz A, Edwards P, et al. Merlin controls the repair capacity of Schwann cells after injury by regulating Hippo/YAP activity. J Cell Biol. 2017;216:495-510 pubmed publisher
  • immunocytochemistry; human; 1:800; fig 6g
Fallahi Sichani M, Becker V, Izar B, Baker G, Lin J, Boswell S, et al. Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly dividing de-differentiated state. Mol Syst Biol. 2017;13:905 pubmed publisher
  • chromatin immunoprecipitation; human; loading ...; fig 3h
  • immunoprecipitation; human; loading ...; fig 2b
  • western blot; human; 1:1000; loading ...; fig 1e
Liu L, Guan H, Li Y, Ying Z, Wu J, Zhu X, et al. Astrocyte Elevated Gene 1 Interacts with Acetyltransferase p300 and c-Jun To Promote Tumor Aggressiveness. Mol Cell Biol. 2017;37: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 6b
Farsam V, Basu A, Gatzka M, Treiber N, Schneider L, Mulaw M, et al. Senescent fibroblast-derived Chemerin promotes squamous cell carcinoma migration. Oncotarget. 2016;7:83554-83569 pubmed publisher
  • western blot; human; loading ...; fig 4
Gong J, Tu W, Han J, He J, Liu J, Han P, et al. Hepatic SATB1 induces paracrine activation of hepatic stellate cells and is upregulated by HBx. Sci Rep. 2016;6:37717 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 3a
Flütsch A, Henry K, Mantuano E, Lam M, Shibayama M, Takahashi K, et al. Evidence that LDL receptor-related protein 1 acts as an early injury detection receptor and activates c-Jun in Schwann cells. Neuroreport. 2016;27:1305-1311 pubmed
  • western blot; mouse; 1:1000; loading ...; fig 3a
Zhang Q, Zhang Y, Parsels J, Lohse I, Lawrence T, Pasca di Magliano M, et al. Fbxw7 Deletion Accelerates KrasG12D-Driven Pancreatic Tumorigenesis via Yap Accumulation. Neoplasia. 2016;18:666-673 pubmed publisher
  • western blot; human; 1:200; fig st1
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  • western blot; mouse; fig 3
Hrdinka M, Sudan K, Just S, Drobek A, Stepanek O, Schluter D, et al. Normal Development and Function of T Cells in Proline Rich 7 (Prr7) Deficient Mice. PLoS ONE. 2016;11:e0162863 pubmed publisher
  • western blot; mouse; fig 3
Vernia S, Edwards Y, Han M, Cavanagh Kyros J, Barrett T, Kim J, et al. An alternative splicing program promotes adipose tissue thermogenesis. elife. 2016;5: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 5d
Zhang K, Cai H, Gao S, Yang G, Deng H, Xu G, et al. TNFSF15 suppresses VEGF production in endothelial cells by stimulating miR-29b expression via activation of JNK-GATA3 signals. Oncotarget. 2016;7:69436-69449 pubmed publisher
  • western blot; mouse; loading ...; fig s4a
Nadeau Vallée M, Boudreault A, Leimert K, Hou X, Obari D, Madaan A, et al. Uterotonic Neuromedin U Receptor 2 and Its Ligands Are Upregulated by Inflammation in Mice and Humans, and Elicit Preterm Birth. Biol Reprod. 2016;95:72 pubmed
  • western blot; mouse; loading ...; fig 6a
Pfister J, D Mello S. Regulation of Neuronal Survival by Nucleophosmin 1 (NPM1) Is Dependent on Its Expression Level, Subcellular Localization, and Oligomerization Status. J Biol Chem. 2016;291:20787-97 pubmed publisher
  • western blot; mouse; fig 7d
Ramo K, Sugamura K, Craige S, Keaney J, Davis R. Suppression of ischemia in arterial occlusive disease by JNK-promoted native collateral artery development. elife. 2016;5: pubmed publisher
  • western blot; human; loading ...
Lee A, Kranzusch P, Doudna J, Cate J. eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation. Nature. 2016;536:96-9 pubmed
  • western blot; mouse; loading ...; fig 4b
Wang J, Zhou J, Kho D, Reiners J, Wu G. Role for DUSP1 (dual-specificity protein phosphatase 1) in the regulation of autophagy. Autophagy. 2016;12:1791-1803 pubmed
  • western blot; human; loading ...; fig 8b
Li Y, Jiang D, Zhang Q, Liu X, Cai Z. Ubiquitin-specific protease 4 inhibits breast cancer cell growth through the upregulation of PDCD4. Int J Mol Med. 2016;38:803-11 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s3
Tambe M, Narvi E, Kallio M. Reduced levels of Dusp3/Vhr phosphatase impair normal spindle bipolarity in an Erk1/2 activity-dependent manner. FEBS Lett. 2016;590:2757-67 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 6a
Egea Jimenez A, Gallardo R, Garcia Pino A, Ivarsson Y, Wawrzyniak A, Kashyap R, et al. Frizzled 7 and PIP2 binding by syntenin PDZ2 domain supports Frizzled 7 trafficking and signalling. Nat Commun. 2016;7:12101 pubmed publisher
  • western blot; rat; 1:1000; fig 3
Liu L, Lv G, Ning C, Yang Y, Zhu J. Therapeutic effects of 1,25-dihydroxyvitamin D3 on diabetes-induced liver complications in a rat model. Exp Ther Med. 2016;11:2284-2292 pubmed
  • western blot; human; 1:1000; fig 5d
Xu Z, Bu Y, Chitnis N, Koumenis C, Fuchs S, Diehl J. miR-216b regulation of c-Jun mediates GADD153/CHOP-dependent apoptosis. Nat Commun. 2016;7:11422 pubmed publisher
  • western blot; mouse; fig 1
Tortola L, Nitsch R, Bertrand M, Kogler M, Redouane Y, Kozieradzki I, et al. The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate. Cell Rep. 2016;15:1481-1492 pubmed publisher
  • chromatin immunoprecipitation; human; fig 5
Zhang Y, He Q, Hu Z, Feng Y, Fan L, Tang Z, et al. Long noncoding RNA LINP1 regulates repair of DNA double-strand breaks in triple-negative breast cancer. Nat Struct Mol Biol. 2016;23:522-30 pubmed publisher
  • western blot; mouse; fig 2
Kim B, Silverman S, Liu Y, Wordinger R, Pang I, Clark A. In vitro and in vivo neuroprotective effects of cJun N-terminal kinase inhibitors on retinal ganglion cells. Mol Neurodegener. 2016;11:30 pubmed publisher
  • western blot; human; fig 6
An X, Zhao Z, Luo Y, Zhang R, Tang X, Hao D, et al. Netrin-1 suppresses the MEK/ERK pathway and ITGB4 in pancreatic cancer. Oncotarget. 2016;7:24719-33 pubmed publisher
  • western blot; mouse; 1:1000; fig s4
Antony A, Paillard M, Moffat C, Juskeviciute E, Correnti J, Bolon B, et al. MICU1 regulation of mitochondrial Ca(2+) uptake dictates survival and tissue regeneration. Nat Commun. 2016;7:10955 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:50; fig 4
  • western blot; human; fig 1
Bleckmann A, Conradi L, Menck K, Schmick N, Schubert A, Rietkötter E, et al. β-catenin-independent WNT signaling and Ki67 in contrast to the estrogen receptor status are prognostic and associated with poor prognosis in breast cancer liver metastases. Clin Exp Metastasis. 2016;33:309-23 pubmed publisher
  • western blot; mouse; 1:1000; fig 4c
Avgustinova A, Iravani M, Robertson D, Fearns A, Gao Q, Klingbeil P, et al. Tumour cell-derived Wnt7a recruits and activates fibroblasts to promote tumour aggressiveness. Nat Commun. 2016;7:10305 pubmed publisher
  • western blot; human; loading ...; fig 3a
Lv H, Zhang Z, Wu X, Wang Y, Li C, Gong W, et al. Preclinical Evaluation of Liposomal C8 Ceramide as a Potent anti-Hepatocellular Carcinoma Agent. PLoS ONE. 2016;11:e0145195 pubmed publisher
  • western blot; mouse; fig s1
Ni Y, Nagashimada M, Zhuge F, Zhan L, Nagata N, Tsutsui A, et al. Astaxanthin prevents and reverses diet-induced insulin resistance and steatohepatitis in mice: A comparison with vitamin E. Sci Rep. 2015;5:17192 pubmed publisher
  • western blot; human; 1:250; fig 4
Riesenberg S, Groetchen A, Siddaway R, Bald T, Reinhardt J, Smorra D, et al. MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment. Nat Commun. 2015;6:8755 pubmed publisher
  • immunohistochemistry - frozen section; human; loading ...
Thomsen E, Mich J, Yao Z, Hodge R, Doyle A, Jang S, et al. Fixed single-cell transcriptomic characterization of human radial glial diversity. Nat Methods. 2016;13:87-93 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 1c
  • western blot; mouse; loading ...; fig 1b
Trierweiler C, Hockenjos B, Zatloukal K, Thimme R, Blum H, Wagner E, et al. The transcription factor c-JUN/AP-1 promotes HBV-related liver tumorigenesis in mice. Cell Death Differ. 2016;23:576-82 pubmed publisher
  • western blot; dogs; 1:1000; fig 1b
Neumann Z, Pondenis H, Masyr A, Byrum M, Wycislo K, Fan T. The Association of Endothelin-1 Signaling with Bone Alkaline Phosphatase Expression and Protumorigenic Activities in Canine Osteosarcoma. J Vet Intern Med. 2015;29:1584-94 pubmed publisher
  • western blot; human; fig 4
Wunsch E, Milkiewicz M, Wasik U, Trottier J, Kempińska Podhorodecka A, Elias E, et al. Expression of hepatic Fibroblast Growth Factor 19 is enhanced in Primary Biliary Cirrhosis and correlates with severity of the disease. Sci Rep. 2015;5:13462 pubmed publisher
  • western blot; mouse; 1:500
He J, Quintana M, Sullivan J, L Parry T, J Grevengoed T, Schisler J, et al. MuRF2 regulates PPARγ1 activity to protect against diabetic cardiomyopathy and enhance weight gain induced by a high fat diet. Cardiovasc Diabetol. 2015;14:97 pubmed publisher
  • western blot; mouse; 1:500
Quintana M, He J, Sullivan J, Grevengoed T, Schisler J, Han Y, et al. Muscle ring finger-3 protects against diabetic cardiomyopathy induced by a high fat diet. BMC Endocr Disord. 2015;15:36 pubmed publisher
  • western blot; human; 1:1000; fig 3b
  • western blot; mouse; 1:1000; fig 3a
Zhang S, Hu Y, Huang Y, Xu H, Wu G, Dai H. Heat shock protein 27 promotes cell proliferation through activator protein-1 in lung cancer. Oncol Lett. 2015;9:2572-2576 pubmed
  • western blot; mouse; fig 4b
Lebrun Julien F, Suter U. Combined HDAC1 and HDAC2 Depletion Promotes Retinal Ganglion Cell Survival After Injury Through Reduction of p53 Target Gene Expression. ASN Neuro. 2015;7: pubmed publisher
  • immunocytochemistry; mouse; 1:100; fig 5
  • western blot; mouse; 1:1000; fig 5
Liu J, Han Q, Peng T, Peng M, Wei B, Li D, et al. The oncogene c-Jun impedes somatic cell reprogramming. Nat Cell Biol. 2015;17:856-67 pubmed publisher
  • western blot; mouse
Krokowski D, Jobava R, Guan B, Farabaugh K, Wu J, Majumder M, et al. Coordinated Regulation of the Neutral Amino Acid Transporter SNAT2 and the Protein Phosphatase Subunit GADD34 Promotes Adaptation to Increased Extracellular Osmolarity. J Biol Chem. 2015;290:17822-37 pubmed publisher
  • western blot; human
Teng Y, Radde B, Litchfield L, Ivanova M, Prough R, Clark B, et al. Dehydroepiandrosterone Activation of G-protein-coupled Estrogen Receptor Rapidly Stimulates MicroRNA-21 Transcription in Human Hepatocellular Carcinoma Cells. J Biol Chem. 2015;290:15799-811 pubmed publisher
  • western blot; mouse; 1:1000; fig 2
Ko R, Park J, Ha H, Choi Y, Lee S. Glycogen synthase kinase 3β ubiquitination by TRAF6 regulates TLR3-mediated pro-inflammatory cytokine production. Nat Commun. 2015;6:6765 pubmed publisher
  • western blot; Leishmania ; fig 2b
Isnard A, Christian J, Kodiha M, Stochaj U, McMaster W, Olivier M. Impact of Leishmania infection on host macrophage nuclear physiology and nucleopore complex integrity. PLoS Pathog. 2015;11:e1004776 pubmed publisher
  • reverse phase protein lysate microarray; human; tbl s2
  • immunocytochemistry; human; 1:800; fig 5
Fallahi Sichani M, Moerke N, Niepel M, Zhang T, Gray N, Sorger P. Systematic analysis of BRAF(V600E) melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis. Mol Syst Biol. 2015;11:797 pubmed publisher
  • western blot; human; fig 4
Li T, Su L, Lei Y, Liu X, Zhang Y, Liu X. DDIT3 and KAT2A Proteins Regulate TNFRSF10A and TNFRSF10B Expression in Endoplasmic Reticulum Stress-mediated Apoptosis in Human Lung Cancer Cells. J Biol Chem. 2015;290:11108-18 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:100
Hollis E, Ishiko N, Tolentino K, Doherty E, Rodríguez M, Calcutt N, et al. A novel and robust conditioning lesion induced by ethidium bromide. Exp Neurol. 2015;265:30-9 pubmed publisher
  • western blot; human; fig s7
Menck K, Scharf C, Bleckmann A, Dyck L, Rost U, Wenzel D, et al. Tumor-derived microvesicles mediate human breast cancer invasion through differentially glycosylated EMMPRIN. J Mol Cell Biol. 2015;7:143-53 pubmed publisher
  • western blot; human; loading ...; fig 2a
Suzuki S, Okada M, Shibuya K, Seino M, Sato A, Takeda H, et al. JNK suppression of chemotherapeutic agents-induced ROS confers chemoresistance on pancreatic cancer stem cells. Oncotarget. 2015;6:458-70 pubmed
  • western blot; human; 1:1000; fig 6
Leung C, Yeung T, Yip K, Pradeep S, Balasubramanian L, Liu J, et al. Calcium-dependent FAK/CREB/TNNC1 signalling mediates the effect of stromal MFAP5 on ovarian cancer metastatic potential. Nat Commun. 2014;5:5092 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 5
  • western blot; mouse; fig 5
Matsuyama M, Nomori A, Nakakuni K, Shimono A, Fukushima M. Secreted Frizzled-related protein 1 (Sfrp1) regulates the progression of renal fibrosis in a mouse model of obstructive nephropathy. J Biol Chem. 2014;289:31526-33 pubmed publisher
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product information
SKU :
9165L
Product-Name :
c-Jun (60A8) Rabbit mAb
Size :
300 ul
Price-(USD) :
574 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Chromatin Immunoprecipitation
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
43, 48
Host :
Rabbit
Target :
JUN
Primary-Protein :
Jun
Alt-Names :
AP-1,AP1,Activator protein 1,JUN,Jun activation domain binding protein,Proto-oncogene c-Jun,Transcription factor AP-1,V-jun avian sarcoma virus 17 oncogene homolog,c-Jun,enhancer-binding protein AP1,jun oncogene,p39,v-jun sarcoma virus 17 oncogene homolog
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.