product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-SEK1/MKK4 (Ser257/Thr261) Antibody
catalog :
9156
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:250; loading ...; fig 1a
  • western blot; mouse; 1:250; loading ...; fig 2b, 3b
Ma J, Goodwani S, Acton P, Buggia Prevot V, Kesler S, Jamal I, et al. Inhibition of dual leucine zipper kinase prevents chemotherapy-induced peripheral neuropathy and cognitive impairments. Pain. 2021;162:2599-2612 pubmed publisher
  • western blot; mouse; loading ...; fig 4g
Fu Y, Ding Y, Wang Q, Zhu F, Tan Y, Lu X, et al. Blood-stage malaria parasites manipulate host innate immune responses through the induction of sFGL2. Sci Adv. 2020;6:eaay9269 pubmed publisher
  • western blot; human; loading ...; fig 4d
Li Z, Mbah N, Overmeyer J, Sarver J, George S, Trabbic C, et al. The JNK signaling pathway plays a key role in methuosis (non-apoptotic cell death) induced by MOMIPP in glioblastoma. BMC Cancer. 2019;19:77 pubmed publisher
  • western blot; mouse; loading ...; fig 5a
Tormos A, Rius Pérez S, Jorques M, Rada P, Ramírez L, Valverde A, et al. p38α regulates actin cytoskeleton and cytokinesis in hepatocytes during development and aging. PLoS ONE. 2017;12:e0171738 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 2-s1
Walker L, Summers D, Sasaki Y, Brace E, Milbrandt J, DiAntonio A. MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2. elife. 2017;6: pubmed publisher
  • western blot; human; 1:200; fig st1
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
Brunen D, Garcia Barchino M, Malani D, Jagalur Basheer N, Lieftink C, Beijersbergen R, et al. Intrinsic resistance to PIM kinase inhibition in AML through p38?-mediated feedback activation of mTOR signaling. Oncotarget. 2016;7:37407-37419 pubmed publisher
product information
SKU :
9156S
Product-Name :
Phospho-SEK1/MKK4 (Ser257/Thr261) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R, Dm, (X, Z)
Applications :
Western blot
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
44
Host :
Rabbit
Target :
MKK4 (Ser257/Thr261) phosphate
Primary-Protein :
MKK4
Alt-Names :
Dual specificity mitogen-activated protein kinase kinase 4,JNK activating kinase 1,JNK-activated kinase 1,JNK-activating kinase 1,JNKK,JNKK1,MAP kinase kinase 4,MAP2K4,MAPK/ERK kinase 4,MAPKK 4,MAPKK4,MEK 4,MEK4,MKK4,MP2K4,PRKMK4,SAPK/ERK kinase 1,SEK1,SERK1,c-Jun N-terminal kinase kinase 1,mitogen-activated protein kinase kinase 4
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.