| Published Application/Species/Dilution | Reference |
|---|
- immunohistochemistry - paraffin section; human; fig 6
- western blot; human; 1:500; fig 5
- western blot; mouse; 1:500; fig 4
| Peda J, Salah S, Wallace D, Fields P, Grantham C, Fields T, et al. Autocrine IL-10 activation of the STAT3 pathway is required for pathological macrophage differentiation in polycystic kidney disease. Dis Model Mech. 2016;9:1051-61 pubmed publisher |
- immunohistochemistry; human; 1:25; fig e5
| Shu S, Lin C, He H, Witwicki R, Tabassum D, Roberts J, et al. Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer. Nature. 2016;529:413-7 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; fig 5
- western blot; human; fig 3
| Tsuboki J, Fujiwara Y, Horlad H, Shiraishi D, Nohara T, Tayama S, et al. Onionin A inhibits ovarian cancer progression by suppressing cancer cell proliferation and the protumour function of macrophages. Sci Rep. 2016;6:29588 pubmed publisher |
- western blot; mouse; fig 2
| Sakamoto K, Wehde B, Rädler P, Triplett A, Wagner K. Generation of Janus kinase 1 (JAK1) conditional knockout mice. Genesis. 2016;54:582-588 pubmed publisher |
- western blot; mouse; 1:1000; fig 6
| Hammoud A, Kirstein N, Mournetas V, Darracq A, Broc S, Blanchard C, et al. Murine Embryonic Stem Cell Plasticity Is Regulated through Klf5 and Maintained by Metalloproteinase MMP1 and Hypoxia. PLoS ONE. 2016;11:e0146281 pubmed publisher |
- immunohistochemistry - free floating section; rat; 1:300
| Moravcová S, Cervena K, Pačesová D, Bendova Z. Identification of STAT3 and STAT5 proteins in the rat suprachiasmatic nucleus and the Day/Night difference in astrocytic STAT3 phosphorylation in response to lipopolysaccharide. J Neurosci Res. 2016;94:99-108 pubmed publisher |
- western blot; mouse; fig 7
| Park J, Kotani T, Konno T, Setiawan J, Kitamura Y, Imada S, et al. Promotion of Intestinal Epithelial Cell Turnover by Commensal Bacteria: Role of Short-Chain Fatty Acids. PLoS ONE. 2016;11:e0156334 pubmed publisher |
- western blot; mouse; 1:1000
| Chandler R, Damrauer J, Raab J, Schisler J, Wilkerson M, Didion J, et al. Coexistent ARID1A-PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling. Nat Commun. 2015;6:6118 pubmed publisher |
| Maliqueo M, Sundstrom Poromaa I, Vanky E, Fornes R, Benrick A, Akerud H, et al. Placental STAT3 signaling is activated in women with polycystic ovary syndrome. Hum Reprod. 2015;30:692-700 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:400
| Andreasen S, Therkildsen M, Grauslund M, Friis-Hansen L, Wessel I, Homøe P. Activation of the interleukin-6/Janus kinase/STAT3 pathway in pleomorphic adenoma of the parotid gland. APMIS. 2015;123:706-15 pubmed publisher |
- western blot; human; fig s5
| Dorosz S, Ginolhac A, Kahne T, Naumann M, Sauter T, Salsmann A, et al. Role of Calprotectin as a Modulator of the IL27-Mediated Proinflammatory Effect on Endothelial Cells. Mediators Inflamm. 2015;2015:737310 pubmed publisher |
- western blot; mouse; 1:1000
| Gopinathan G, Milagre C, Pearce O, Reynolds L, Hodivala-Dilke K, Leinster D, et al. Interleukin-6 Stimulates Defective Angiogenesis. Cancer Res. 2015;75:3098-107 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; fig 1
| Aparicio-Domingo P, Romera-Hernandez M, Karrich J, Cornelissen F, Papazian N, Lindenbergh-Kortleve D, et al. Type 3 innate lymphoid cells maintain intestinal epithelial stem cells after tissue damage. J Exp Med. 2015;212:1783-91 pubmed publisher |
- immunohistochemistry - frozen section; mouse
- western blot; mouse
| Coorey N, Shen W, Zhu L, Gillies M. Differential Expression of IL-6/gp130 Cytokines, Jak-STAT Signaling and Neuroprotection After Müller Cell Ablation in a Transgenic Mouse Model. Invest Ophthalmol Vis Sci. 2015;56:2151-61 pubmed publisher |
- immunohistochemistry; human; fig 2
| Eriksson P, Aine M, Veerla S, Liedberg F, Sjödahl G, Hoglund M. Molecular subtypes of urothelial carcinoma are defined by specific gene regulatory systems. BMC Med Genomics. 2015;8:25 pubmed publisher |
- immunocytochemistry; human; 1:100
| Itou J, Tanaka S, Sato F, Akiyama R, Kawakami Y, Toi M. An optical labeling-based proliferation assay system reveals the paracrine effect of interleukin-6 in breast cancer. Biochim Biophys Acta. 2015;1853:27-40 pubmed publisher |
- western blot; human; 1:1000; fig 1
| Hutchins A, Takahashi Y, Miranda-Saavedra D. Genomic analysis of LPS-stimulated myeloid cells identifies a common pro-inflammatory response but divergent IL-10 anti-inflammatory responses. Sci Rep. 2015;5:9100 pubmed publisher |
- immunohistochemistry; mouse; 1:800
| Dabydeen S, Kang K, Diaz-Cruz E, Alamri A, Axelrod M, Bouker K, et al. Comparison of tamoxifen and letrozole response in mammary preneoplasia of ER and aromatase overexpressing mice defines an immune-associated gene signature linked to tamoxifen resistance. Carcinogenesis. 2015;36:122-32 pubmed publisher |
- western blot; human; fig 1
| Yang L, Li Y, Bhattacharya A, Zhang Y. Inhibition of ERBB2-overexpressing Tumors by Recombinant Human Prolidase and Its Enzymatically Inactive Mutant. EBioMedicine. 2015;2:396-405 pubmed |
- western blot; rat
- immunohistochemistry; rat
| Harris R, Apolzan J. Hexosamine biosynthetic pathway activity in leptin resistant sucrose-drinking rats. Physiol Behav. 2015;138:208-18 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:100; fig 3
| Binder Gallimidi A, Fischman S, Revach B, Bulvik R, Maliutina A, Rubinstein A, et al. Periodontal pathogens Porphyromonas gingivalis and Fusobacterium nucleatum promote tumor progression in an oral-specific chemical carcinogenesis model. Oncotarget. 2015;6:22613-23 pubmed |
- western blot; human; 1:250
| Tréhoux S, Lahdaoui F, Delpu Y, Renaud F, Leteurtre E, Torrisani J, et al. Micro-RNAs miR-29a and miR-330-5p function as tumor suppressors by targeting the MUC1 mucin in pancreatic cancer cells. Biochim Biophys Acta. 2015;1853:2392-403 pubmed publisher |
- flow cytometry; mouse
- western blot; human; fig 1c
- western blot; mouse; fig 1a
- immunoprecipitation; mouse; fig 2a
| Ulaganathan V, Sperl B, Rapp U, Ullrich A. Germline variant FGFR4 p.G388R exposes a membrane-proximal STAT3 binding site. Nature. 2015;528:570-4 pubmed publisher |
| Asano S, Arvapalli R, Manne N, Maheshwari M, Ma B, Rice K, et al. Cerium oxide nanoparticle treatment ameliorates peritonitis-induced diaphragm dysfunction. Int J Nanomedicine. 2015;10:6215-25 pubmed publisher |
| He D, Chen H, Muramatsu H, Lasek A. Ethanol activates midkine and anaplastic lymphoma kinase signaling in neuroblastoma cells and in the brain. J Neurochem. 2015;135:508-21 pubmed publisher |
- immunohistochemistry - paraffin section; mouse
- western blot; mouse
| Delgado O, Batten K, Richardson J, Xie X, Gazdar A, Kaisani A, et al. Radiation-enhanced lung cancer progression in a transgenic mouse model of lung cancer is predictive of outcomes in human lung and breast cancer. Clin Cancer Res. 2014;20:1610-22 pubmed publisher |
- immunohistochemistry; mouse
| Ota M, Horiguchi M, Fang V, Shibahara K, Kadota K, Loomis C, et al. Genetic suppression of inflammation blocks the tumor-promoting effects of TGF-β in gastric tissue. Cancer Res. 2014;74:2642-51 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:50
- western blot; mouse; 1:200
| Bless E, Reddy T, Acharya K, Beltz B, Tetel M. Oestradiol and diet modulate energy homeostasis and hypothalamic neurogenesis in the adult female mouse. J Neuroendocrinol. 2014;26:805-16 pubmed publisher |
| Fiallos E, Judkins J, Matlaf L, Prichard M, DITTMER D, Cobbs C, et al. Human cytomegalovirus gene expression in long-term infected glioma stem cells. PLoS ONE. 2014;9:e116178 pubmed publisher |
| Liu B, Cao Y, Huizinga T, Hafler D, Toes R. TLR-mediated STAT3 and ERK activation controls IL-10 secretion by human B cells. Eur J Immunol. 2014;44:2121-9 pubmed publisher |
| Chang P, Wang T, Chang Y, Chu C, Lee C, Hsu H, et al. Autophagy pathway is required for IL-6 induced neuroendocrine differentiation and chemoresistance of prostate cancer LNCaP cells. PLoS ONE. 2014;9:e88556 pubmed publisher |
| Koganti S, de la Paz A, Freeman A, Bhaduri-McIntosh S. B lymphocytes from patients with a hypomorphic mutation in STAT3 resist Epstein-Barr virus-driven cell proliferation. J Virol. 2014;88:516-24 pubmed publisher |
| Waitkus M, Chandrasekharan U, Willard B, Tee T, Hsieh J, Przybycin C, et al. Signal integration and gene induction by a functionally distinct STAT3 phosphoform. Mol Cell Biol. 2014;34:1800-11 pubmed publisher |
- western blot; mouse; 1:2000
| Chucair-Elliott A, Conrady C, Zheng M, Kroll C, Lane T, Carr D. Microglia-induced IL-6 protects against neuronal loss following HSV-1 infection of neural progenitor cells. Glia. 2014;62:1418-34 pubmed publisher |
| Guerrouahen B, Pasquier J, Kaoud N, Maleki M, Beauchamp M, Yasmeen A, et al. Akt-activated endothelium constitutes the niche for residual disease and resistance to bevacizumab in ovarian cancer. Mol Cancer Ther. 2014;13:3123-36 pubmed publisher |
| Kopaliani I, Martin M, Zatschler B, Bortlik K, Müller B, Deussen A. Cell-specific and endothelium-dependent regulations of matrix metalloproteinase-2 in rat aorta. Basic Res Cardiol. 2014;109:419 pubmed publisher |
| Assi H, Espinosa J, Suprise S, SOFRONIEW M, Doherty R, Zamler D, et al. Assessing the role of STAT3 in DC differentiation and autologous DC immunotherapy in mouse models of GBM. PLoS ONE. 2014;9:e96318 pubmed publisher |
| Hou J, Xia Y, Jiang R, Chen D, Xu J, Deng L, et al. PTPRO plays a dual role in hepatic ischemia reperfusion injury through feedback activation of NF-κB. J Hepatol. 2014;60:306-12 pubmed publisher |
| McGuire D, Rowse A, Li H, Peng B, Sestero C, Cashman K, et al. CD5 enhances Th17-cell differentiation by regulating IFN-γ response and RORγt localization. Eur J Immunol. 2014;44:1137-42 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:80
| Schlederer M, Mueller K, Haybaeck J, Heider S, Huttary N, Rosner M, et al. Reliable quantification of protein expression and cellular localization in histological sections. PLoS ONE. 2014;9:e100822 pubmed publisher |
- immunohistochemistry - paraffin section; human
- immunohistochemistry - paraffin section; mouse
| Chan S, Rickert C, Vermi W, Sheehan K, Arthur C, Allen J, et al. Dysregulated STAT1-SOCS1 control of JAK2 promotes mammary luminal progenitor cell survival and drives ERα(+) tumorigenesis. Cell Death Differ. 2014;21:234-46 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:100; fig 3
- western blot; mouse; 1:1000; fig 1
| Tyzack G, Sitnikov S, Barson D, Adams-Carr K, Lau N, Kwok J, et al. Astrocyte response to motor neuron injury promotes structural synaptic plasticity via STAT3-regulated TSP-1 expression. Nat Commun. 2014;5:4294 pubmed publisher |
- chromatin immunoprecipitation; mouse
- western blot; mouse
| Chong H, Chan J, Goh C, Gounko N, Luo B, Wang X, et al. Angiopoietin-like 4 stimulates STAT3-mediated iNOS expression and enhances angiogenesis to accelerate wound healing in diabetic mice. Mol Ther. 2014;22:1593-604 pubmed publisher |
- western blot; human; 1:1,000
| Gu L, Talati P, Vogiatzi P, Romero-Weaver A, Abdulghani J, Liao Z, et al. Pharmacologic suppression of JAK1/2 by JAK1/2 inhibitor AZD1480 potently inhibits IL-6-induced experimental prostate cancer metastases formation. Mol Cancer Ther. 2014;13:1246-58 pubmed publisher |
- western blot; rat; 1:2000
| Bloomer S, Kregel K, Brown K. Heat stress stimulates hepcidin mRNA expression and C/EBPα protein expression in aged rodent liver. Arch Gerontol Geriatr. 2014;58:145-52 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:5000
| Briggs D, Lockie S, Benzler J, Wu Q, Stark R, Reichenbach A, et al. Evidence that diet-induced hyperleptinemia, but not hypothalamic gliosis, causes ghrelin resistance in NPY/AgRP neurons of male mice. Endocrinology. 2014;155:2411-22 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:100
| Kong L, Wei J, Haider A, Liebelt B, Ling X, Conrad C, et al. Therapeutic targets in subependymoma. J Neuroimmunol. 2014;277:168-75 pubmed publisher |
- western blot; mouse; 1:1000
| Taylor J, Minter M, Newman A, Zhang M, Adlard P, Crack P. Type-1 interferon signaling mediates neuro-inflammatory events in models of Alzheimer's disease. Neurobiol Aging. 2014;35:1012-23 pubmed publisher |
- immunocytochemistry; human
| Zhao Y, Park S, Bagchi M, Taylor R, Katzenellenbogen B. The coregulator, repressor of estrogen receptor activity (REA), is a crucial regulator of the timing and magnitude of uterine decidualization. Endocrinology. 2013;154:1349-60 pubmed publisher |
| Paugh B, Zhu X, Qu C, Endersby R, Diaz A, Zhang J, et al. Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas. Cancer Res. 2013;73:6219-29 pubmed publisher |
- western blot; mouse
- immunohistochemistry; mouse
| Sutherland J, Keightley R, Nixon B, Roman S, Robker R, Russell D, et al. Suppressor of cytokine signaling 4 (SOCS4): moderator of ovarian primordial follicle activation. J Cell Physiol. 2012;227:1188-98 pubmed publisher |
- immunohistochemistry - frozen section; rat; 1:100
| Tripathi R, McTigue D. Chronically increased ciliary neurotrophic factor and fibroblast growth factor-2 expression after spinal contusion in rats. J Comp Neurol. 2008;510:129-44 pubmed publisher |
- immunohistochemistry; mouse
| Syu L, El-Zaatari M, Eaton K, Liu Z, Tetarbe M, Keeley T, et al. Transgenic expression of interferon-γ in mouse stomach leads to inflammation, metaplasia, and dysplasia. Am J Pathol. 2012;181:2114-25 pubmed publisher |
| Li Y, Deuring J, Peppelenbosch M, Kuipers E, de Haar C, van der Woude C. STAT1, STAT6 and adenosine 3',5'-cyclic monophosphate (cAMP) signaling drive SOCS3 expression in inactive ulcerative colitis. Mol Med. 2012;18:1412-9 pubmed publisher |
| Freudenberg J, Ghosh S, Lackford B, Yellaboina S, Zheng X, Li R, et al. Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity. Nucleic Acids Res. 2012;40:3364-77 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:1000
| Caron E, Sachot C, Prevot V, Bouret S. Distribution of leptin-sensitive cells in the postnatal and adult mouse brain. J Comp Neurol. 2010;518:459-76 pubmed publisher |
| Hou D, Jin Y, Nie X, Zhang M, Ta N, Zhao L, et al. Derivation of Porcine Embryonic Stem-Like Cells from In Vitro-Produced Blastocyst-Stage Embryos. Sci Rep. 2016;6:25838 pubmed publisher |
| Uehara Y, Inoue M, Fukuda K, Yamakoshi H, Hosoi Y, Kanda H, et al. Inhibition of β-catenin and STAT3 with a curcumin analog suppresses gastric carcinogenesis in vivo. Gastric Cancer. 2015;18:774-83 pubmed publisher |
| Park J, Kim M, Kang S, Jannasch A, Cooper B, Patterson J, et al. Short-chain fatty acids induce both effector and regulatory T cells by suppression of histone deacetylases and regulation of the mTOR-S6K pathway. Mucosal Immunol. 2015;8:80-93 pubmed publisher |
| Haapaniemi E, Kaustio M, Rajala H, van Adrichem A, Kainulainen L, Glumoff V, et al. Autoimmunity, hypogammaglobulinemia, lymphoproliferation, and mycobacterial disease in patients with activating mutations in STAT3. Blood. 2015;125:639-48 pubmed publisher |
| Desai B, Harris R. Leptin in the hindbrain facilitates phosphorylation of STAT3 in the hypothalamus. Am J Physiol Endocrinol Metab. 2015;308:E351-61 pubmed publisher |
| Lee D, Jeong J, Chun S, Chua S, Jo Y. Interplay between glucose and leptin signalling determines the strength of GABAergic synapses at POMC neurons. Nat Commun. 2015;6:6618 pubmed publisher |
| Minter M, Main B, Brody K, Zhang M, Taylor J, Crack P. Soluble amyloid triggers a myeloid differentiation factor 88 and interferon regulatory factor 7 dependent neuronal type-1 interferon response in vitro. J Neuroinflammation. 2015;12:71 pubmed publisher |
| Grum-Schwensen B, Klingelhofer J, Beck M, Bonefeld C, Hamerlik P, Guldberg P, et al. S100A4-neutralizing antibody suppresses spontaneous tumor progression, pre-metastatic niche formation and alters T-cell polarization balance. BMC Cancer. 2015;15:1034 pubmed publisher |
| Das L, Rosenjack J, Au L, Galle P, Hansen M, Cathcart M, et al. Hyper-inflammation and skin destruction mediated by rosiglitazone activation of macrophages in IL-6 deficiency. J Invest Dermatol. 2015;135:389-99 pubmed publisher |
| Milner J, Vogel T, Forbes L, Ma C, Stray-Pedersen A, Niemela J, et al. Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations. Blood. 2015;125:591-9 pubmed publisher |
| Wang Y, Chen Q, Zhang Z, Jiang F, Meng X, Yan H. Interleukin-10 overexpression improves the function of endothelial progenitor cells stimulated with TNF-α through the activation of the STAT3 signaling pathway. Int J Mol Med. 2015;35:471-7 pubmed publisher |
| de Masson A, Bouaziz J, Le Buanec H, Robin M, O'Meara A, Parquet N, et al. CD24(hi)CD27⁺ and plasmablast-like regulatory B cells in human chronic graft-versus-host disease. Blood. 2015;125:1830-9 pubmed publisher |
| Kanagavelu S, Flores C, Termini J, Riveron R, Romero L, Chung K, et al. TIR-domain-containing adapter-inducing interferon-β (TRIF) regulates Th17-mediated intestinal immunopathology in colitis. Mucosal Immunol. 2015;8:296-306 pubmed publisher |
| Minter M, Zhang M, Ates R, Taylor J, Crack P. Type-1 interferons contribute to oxygen glucose deprivation induced neuro-inflammation in BE(2)M17 human neuroblastoma cells. J Neuroinflammation. 2014;11:43 pubmed publisher |
| Zhu W, Zhang W, Shou W, Field L. P53 inhibition exacerbates late-stage anthracycline cardiotoxicity. Cardiovasc Res. 2014;103:81-9 pubmed publisher |
| Ekyalongo R, Mukohara T, Funakoshi Y, Tomioka H, Kataoka Y, Shimono Y, et al. TYRO3 as a potential therapeutic target in breast cancer. Anticancer Res. 2014;34:3337-45 pubmed |
| Yoshida R, Nakayama H, Nagata M, Hirosue A, Tanaka T, Kawahara K, et al. Overexpression of nucleostemin contributes to an advanced malignant phenotype and a poor prognosis in oral squamous cell carcinoma. Br J Cancer. 2014;111:2308-15 pubmed publisher |
| Mano Y, Aishima S, Kubo Y, Tanaka Y, Motomura T, Toshima T, et al. Correlation between biological marker expression and fluorine-18 fluorodeoxyglucose uptake in hepatocellular carcinoma. Am J Clin Pathol. 2014;142:391-7 pubmed publisher |
| Deng J, Yuan S, Pennati A, Murphy J, Wu J, Lawson D, et al. Engineered fusokine GIFT4 licenses the ability of B cells to trigger a tumoricidal T-cell response. Cancer Res. 2014;74:4133-44 pubmed publisher |
| Vinnikov I, Hajdukiewicz K, Reymann J, Beneke J, Czajkowski R, Roth L, et al. Hypothalamic miR-103 protects from hyperphagic obesity in mice. J Neurosci. 2014;34:10659-74 pubmed publisher |
| Cheng Z, Li-Sha G, Jing-Lin Z, Wen-Wu Z, Xue-Si C, Xing-Xing C, et al. Protective role of the cholinergic anti-inflammatory pathway in a mouse model of viral myocarditis. PLoS ONE. 2014;9:e112719 pubmed publisher |
| Lin G, Yang L, Wang X, Chen Y, Tang W, Chen L, et al. STAT3 Tyr705 phosphorylation affects clinical outcome in patients with newly diagnosed supratentorial glioblastoma. Med Oncol. 2014;31:924 pubmed publisher |
| Datta S, Parajuli N, Tymoszuk P, Ottina E, Parson W, Sgonc R, et al. Replenishment of the B cell compartment after doxorubicin-induced hematopoietic toxicity is facilitated by STAT1. J Leukoc Biol. 2014;95:853-66 pubmed publisher |
| Knudsen S, Mac A, Henriksen L, van Deurs B, Grøvdal L. EGFR signaling patterns are regulated by its different ligands. Growth Factors. 2014;32:155-63 pubmed publisher |
| Isozaki H, Yasugi M, Takigawa N, Hotta K, Ichihara E, Taniguchi A, et al. A new human lung adenocarcinoma cell line harboring the EML4-ALK fusion gene. Jpn J Clin Oncol. 2014;44:963-8 pubmed publisher |
| Rosich L, Montraveta A, Xargay-Torrent S, López-Guerra M, Roldán J, Aymerich M, et al. Dual PI3K/mTOR inhibition is required to effectively impair microenvironment survival signals in mantle cell lymphoma. Oncotarget. 2014;5:6788-800 pubmed |
| Wang X, Lin G, Lin Z, Chen Y, Chen Y, Zhang J, et al. Association of pSTAT3-VEGF signaling pathway with peritumoral edema in newly diagnosed glioblastoma: an immunohistochemical study. Int J Clin Exp Pathol. 2014;7:6133-40 pubmed |
| Folgiero V, Goffredo B, Filippini P, Masetti R, Bonanno G, Caruso R, et al. Indoleamine 2,3-dioxygenase 1 (IDO1) activity in leukemia blasts correlates with poor outcome in childhood acute myeloid leukemia. Oncotarget. 2014;5:2052-64 pubmed |
| Pelosi M, De Rossi M, Barberi L, Musaro A. IL-6 impairs myogenic differentiation by downmodulation of p90RSK/eEF2 and mTOR/p70S6K axes, without affecting AKT activity. Biomed Res Int. 2014;2014:206026 pubmed publisher |
| Bagci H, Laurin M, Huber J, Muller W, Cote J. Impaired cell death and mammary gland involution in the absence of Dock1 and Rac1 signaling. Cell Death Dis. 2014;5:e1375 pubmed publisher |
| Alnaeeli M, Raaka B, Gavrilova O, Teng R, Chanturiya T, Noguchi C. Erythropoietin signaling: a novel regulator of white adipose tissue inflammation during diet-induced obesity. Diabetes. 2014;63:2415-31 pubmed publisher |
| Wang S, Chen X, Tang M. MicroRNA-216a inhibits pancreatic cancer by directly targeting Janus kinase 2. Oncol Rep. 2014;32:2824-30 pubmed publisher |
| Kim J, Sohn B, Lee H, Kim S, Yoo J, Park Y, et al. Genomic predictors for recurrence patterns of hepatocellular carcinoma: model derivation and validation. PLoS Med. 2014;11:e1001770 pubmed publisher |
| Saito Y, Yukawa A, Matozaki M, Mikami H, Yamagami T, Yamagishi N, et al. Nmi interacts with Hsp105β and enhances the Hsp105β-mediated Hsp70 expression. Exp Cell Res. 2014;327:163-70 pubmed publisher |
| Lo J, Patel V, Wang Z, Levasseur J, Kaufman S, Penninger J, et al. Angiotensin-converting enzyme 2 antagonizes angiotensin II-induced pressor response and NADPH oxidase activation in Wistar-Kyoto rats and spontaneously hypertensive rats. Exp Physiol. 2013;98:109-22 pubmed publisher |
| Mano Y, Aishima S, Fujita N, Tanaka Y, Kubo Y, Motomura T, et al. Tumor-associated macrophage promotes tumor progression via STAT3 signaling in hepatocellular carcinoma. Pathobiology. 2013;80:146-54 pubmed publisher |
| Levidou G, Siakantaris M, Papadaki T, Papadavid E, Vassilakopoulos T, Angelopoulou M, et al. A comprehensive immunohistochemical approach of AKT/mTOR pathway and p-STAT3 in mycosis fungoides. J Am Acad Dermatol. 2013;69:375-84 pubmed publisher |
| Aftimos P, Wiedig M, Langouo Fontsa M, Awada A, Ghanem G, Journe F. Sequential use of protein kinase inhibitors potentiates their toxicity to melanoma cells: a rationale to combine targeted drugs based on protein expression inhibition profiles. Int J Oncol. 2013;43:919-26 pubmed publisher |
| Liu B, Stoop J, Huizinga T, Toes R. IL-21 enhances the activity of the TLR-MyD88-STAT3 pathway but not the classical TLR-MyD88-NF-κB pathway in human B cells to boost antibody production. J Immunol. 2013;191:4086-94 pubmed publisher |
| Hyndman B, Gujral T, Krieger J, Cockburn J, Mulligan L. Multiple functional effects of RET kinase domain sequence variants in Hirschsprung disease. Hum Mutat. 2013;34:132-42 pubmed publisher |
| Luo X, Xie H, Long X, Zhou M, Xu Z, Shi B, et al. EGFRvIII mediates hepatocellular carcinoma cell invasion by promoting S100 calcium binding protein A11 expression. PLoS ONE. 2013;8:e83332 pubmed publisher |
| Specht S, Isse K, Nozaki I, Lunz J, Demetris A. SPRR2A expression in cholangiocarcinoma increases local tumor invasiveness but prevents metastasis. Clin Exp Metastasis. 2013;30:877-90 pubmed publisher |
| Zhang H, Yea K, Xie J, Ruiz D, Wilson I, Lerner R. Selecting agonists from single cells infected with combinatorial antibody libraries. Chem Biol. 2013;20:734-41 pubmed publisher |
| Rajala H, Eldfors S, Kuusanmäki H, van Adrichem A, Olson T, Lagström S, et al. Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia. Blood. 2013;121:4541-50 pubmed publisher |
| Wang H, Zhang L, Zhang I, Chen X, Da Fonseca A, Wu S, et al. S100B promotes glioma growth through chemoattraction of myeloid-derived macrophages. Clin Cancer Res. 2013;19:3764-75 pubmed publisher |
| Sevilla L, Latorre V, Sanchis A, Perez P. Epidermal inactivation of the glucocorticoid receptor triggers skin barrier defects and cutaneous inflammation. J Invest Dermatol. 2013;133:361-70 pubmed publisher |
| Lupberger J, Duong F, Fofana I, Zona L, Xiao F, Thumann C, et al. Epidermal growth factor receptor signaling impairs the antiviral activity of interferon-alpha. Hepatology. 2013;58:1225-35 pubmed publisher |
| Sadighi Akha A, Theriot C, Erb-Downward J, McDermott A, Falkowski N, Tyra H, et al. Acute infection of mice with Clostridium difficile leads to eIF2α phosphorylation and pro-survival signalling as part of the mucosal inflammatory response. Immunology. 2013;140:111-22 pubmed publisher |
| Zhu M, Pleasic-Williams S, Lin T, Wunderlich D, Cheng J, Masferrer J. pSTAT3: a target biomarker to study the pharmacology of the anti-IL-21R antibody ATR-107 in human whole blood. J Transl Med. 2013;11:65 pubmed publisher |
| Diermeier-Daucher S, Ortmann O, Buchholz S, Brockhoff G. Trifunctional antibody ertumaxomab: Non-immunological effects on Her2 receptor activity and downstream signaling. MAbs. 2012;4:614-22 pubmed publisher |
| Komohara Y, Horlad H, Ohnishi K, Fujiwara Y, Bai B, Nakagawa T, et al. Importance of direct macrophage-tumor cell interaction on progression of human glioma. Cancer Sci. 2012;103:2165-72 pubmed publisher |
| Ernst M, Wunderlich C, Hess S, Paehler M, Mesaros A, Koralov S, et al. Enhanced Stat3 activation in POMC neurons provokes negative feedback inhibition of leptin and insulin signaling in obesity. J Neurosci. 2009;29:11582-93 pubmed publisher |
| Li S, Wang N, Brodt P. Metastatic cells can escape the proapoptotic effects of TNF-α through increased autocrine IL-6/STAT3 signaling. Cancer Res. 2012;72:865-75 pubmed publisher |
| Naraoka T, Ishibashi Y, Tsuda E, Yamamoto Y, Kusumi T, Kakizaki I, et al. Time-dependent gene expression and immunohistochemical analysis of the injured anterior cruciate ligament. Bone Joint Res. 2012;1:238-44 pubmed publisher |
| Kataoka Y, Mukohara T, Tomioka H, Funakoshi Y, Kiyota N, Fujiwara Y, et al. Foretinib (GSK1363089), a multi-kinase inhibitor of MET and VEGFRs, inhibits growth of gastric cancer cell lines by blocking inter-receptor tyrosine kinase networks. Invest New Drugs. 2012;30:1352-60 pubmed publisher |
| Bauer S, Patterson P. Leukemia inhibitory factor promotes neural stem cell self-renewal in the adult brain. J Neurosci. 2006;26:12089-99 pubmed |
| Jensen T, Schmidt H, Møller H, Donskov F, Høyer M, Sjoegren P, et al. Intratumoral neutrophils and plasmacytoid dendritic cells indicate poor prognosis and are associated with pSTAT3 expression in AJCC stage I/II melanoma. Cancer. 2012;118:2476-85 pubmed publisher |
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