| Published Application/Species/Dilution | Reference |
|---|
- immunohistochemistry - paraffin section; mouse; fig 2
- immunohistochemistry (knockout validation); mouse; fig 2
- western blot (knockout validation); mouse; 1:1000; fig 2
| Schlederer M, Mueller K, Haybaeck J, Heider S, Huttary N, Rosner M, et al. Reliable quantification of protein expression and cellular localization in histological sections. PLoS ONE. 2014;9:e100822 pubmed publisher |
- flow cytometry; mouse; fig 6E
- immunocytochemistry; mouse; 1:100; fig 6D
| Kanda M, Nagai T, Takahashi T, Liu M, Kondou N, Naito A, et al. Leukemia Inhibitory Factor Enhances Endogenous Cardiomyocyte Regeneration after Myocardial Infarction. PLoS ONE. 2016;11:e0156562 pubmed publisher |
- western blot; human; fig 2
| Segatto I, Massarut S, Boyle R, Baldassarre G, Walker D, Belletti B. Preclinical validation of a novel compound targeting p70S6 kinase in breast cancer. Aging (Albany NY). 2016;8:958-76 pubmed publisher |
- western blot; mouse; 1:1000; fig 3
| Drilon A, Somwar R, Wagner J, Vellore N, Eide C, Zabriskie M, et al. A Novel Crizotinib-Resistant Solvent-Front Mutation Responsive to Cabozantinib Therapy in a Patient with ROS1-Rearranged Lung Cancer. Clin Cancer Res. 2016;22:2351-8 pubmed publisher |
| Yang W, Ng F, Chan K, Pu X, Poston R, Ren M, et al. Coronary-Heart-Disease-Associated Genetic Variant at the COL4A1/COL4A2 Locus Affects COL4A1/COL4A2 Expression, Vascular Cell Survival, Atherosclerotic Plaque Stability and Risk of Myocardial Infarction. PLoS Genet. 2016;12:e1006127 pubmed publisher |
- western blot; human; 1:1000; fig 3
| Liu C, Lin S, Hsu H, Yang S, Lin C, Yang M, et al. Suspension survival mediated by PP2A-STAT3-Col XVII determines tumour initiation and metastasis in cancer stem cells. Nat Commun. 2016;7:11798 pubmed publisher |
- western blot; mouse; 1:1000; fig s3
| Moshfegh C, Aires L, Kisielow M, Vogel V. A gonogenic stimulated transition of mouse embryonic stem cells with enhanced control of diverse differentiation pathways. Sci Rep. 2016;6:25104 pubmed publisher |
- western blot; human; fig s5
| Yoshida T, Song L, Bai Y, Kinose F, Li J, Ohaegbulam K, et al. ZEB1 Mediates Acquired Resistance to the Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer. PLoS ONE. 2016;11:e0147344 pubmed publisher |
- western blot; human; fig 3
| Yuzugullu H, Von T, Thorpe L, Walker S, Roberts T, Frank D, et al. NTRK2 activation cooperates with PTEN deficiency in T-ALL through activation of both the PI3K-AKT and JAK-STAT3 pathways. Cell Discov. 2016;2:16030 pubmed publisher |
- western blot; human; fig 4
| Ardini E, Menichincheri M, Banfi P, Bosotti R, De Ponti C, Pulci R, et al. Entrectinib, a Pan-TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications. Mol Cancer Ther. 2016;15:628-39 pubmed publisher |
- immunohistochemistry; mouse; 1:1000; fig 1
| Senzacqua M, Severi I, Perugini J, Acciarini S, Cinti S, Giordano A. Action of Administered Ciliary Neurotrophic Factor on the Mouse Dorsal Vagal Complex. Front Neurosci. 2016;10:289 pubmed publisher |
- western blot; human; 1:100; fig 4j
- immunohistochemistry; mouse; 1:100; fig 4a
| Manda K, Tripathi P, Hsi A, Ning J, Ruzinova M, Liapis H, et al. NFATc1 promotes prostate tumorigenesis and overcomes PTEN loss-induced senescence. Oncogene. 2015;: pubmed publisher |
- western blot; mouse; fig 2c
| Görtz D, Braun G, Maruta Y, Djudjaj S, van Roeyen C, Martin I, et al. Anti-interleukin-6 therapy through application of a monogenic protein inhibitor via gene delivery. Sci Rep. 2015;5:14685 pubmed publisher |
- western blot; human; fig 8
| Pitari M, Rossi M, Amodio N, Botta C, Morelli E, Federico C, et al. Inhibition of miR-21 restores RANKL/OPG ratio in multiple myeloma-derived bone marrow stromal cells and impairs the resorbing activity of mature osteoclasts. Oncotarget. 2015;6:27343-58 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:100
| McBryan J, Fagan A, McCartan D, Bane F, Varešlija D, Cocchiglia S, et al. Transcriptomic Profiling of Sequential Tumors from Breast Cancer Patients Provides a Global View of Metastatic Expression Changes Following Endocrine Therapy. Clin Cancer Res. 2015;21:5371-9 pubmed publisher |
| Wiesauer I, Gaumannmüller C, Steinparzer I, Strobl B, Kovarik P. Promoter occupancy of STAT1 in interferon responses is regulated by processive transcription. Mol Cell Biol. 2015;35:716-27 pubmed publisher |
| Yeh J, Kreimer S, Walker S, Emori M, Krystal H, Richardson A, et al. Granulin, a novel STAT3-interacting protein, enhances STAT3 transcriptional function and correlates with poorer prognosis in breast cancer. Genes Cancer. 2015;6:153-68 pubmed |
- western blot; human; 1:1000
| Barrichon M, Hadi T, Wendremaire M, Ptasinski C, Seigneuric R, Marcion G, et al. Dose-dependent biphasic leptin-induced proliferation is caused by non-specific IL-6/NF-κB pathway activation in human myometrial cells. Br J Pharmacol. 2015;172:2974-90 pubmed publisher |
- western blot; human; 1:1000; fig 5a
| Leve F, Peres-Moreira R, Binato R, Abdelhay E, Morgado-Diaz J. LPA Induces Colon Cancer Cell Proliferation through a Cooperation between the ROCK and STAT-3 Pathways. PLoS ONE. 2015;10:e0139094 pubmed publisher |
- western blot; mouse; 1:1000
| Dicay M, Hirota C, Ronaghan N, Peplowski M, Zaheer R, Carati C, et al. Interferon-γ suppresses intestinal epithelial aquaporin-1 expression via Janus kinase and STAT3 activation. PLoS ONE. 2015;10:e0118713 pubmed publisher |
- western blot; human; fig 3
| Yang Y, Kim D, Seo Y, Park D, Jang H, Choi S, et al. Elevated O-GlcNAcylation promotes colonic inflammation and tumorigenesis by modulating NF-κB signaling. Oncotarget. 2015;6:12529-42 pubmed |
- western blot; mouse; fig 4
| Pajaud J, Ribault C, Ben Mosbah I, Rauch C, Henderson C, Bellaud P, et al. Glutathione transferases P1/P2 regulate the timing of signaling pathway activations and cell cycle progression during mouse liver regeneration. Cell Death Dis. 2015;6:e1598 pubmed publisher |
- western blot; human; 1:1000; fig 1f
| Zimmermann M, Aguilera F, Castellucci M, Rossato M, Costa S, Lunardi C, et al. Chromatin remodelling and autocrine TNFα are required for optimal interleukin-6 expression in activated human neutrophils. Nat Commun. 2015;6:6061 pubmed publisher |
- western blot; mouse; fig s5
| Cattoglio C, Zhang E, Grubisic I, Chiba K, Fong Y, Tjian R. Functional and mechanistic studies of XPC DNA-repair complex as transcriptional coactivator in embryonic stem cells. Proc Natl Acad Sci U S A. 2015;112:E2317-26 pubmed publisher |
| Zanotto-Filho A, Braganhol E, Klafke K, Figueiró F, Terra S, Paludo F, et al. Autophagy inhibition improves the efficacy of curcumin/temozolomide combination therapy in glioblastomas. Cancer Lett. 2015;358:220-31 pubmed publisher |
- western blot; mouse; fig 4c
| Zhang Y, Seo S, Bhattarai S, Bugge K, Searby C, Zhang Q, et al. BBS mutations modify phenotypic expression of CEP290-related ciliopathies. Hum Mol Genet. 2014;23:40-51 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:50
| Cordero J, Ridgway R, Valeri N, Nixon C, Frame M, Muller W, et al. c-Src drives intestinal regeneration and transformation. EMBO J. 2014;33:1474-91 pubmed publisher |
| Matsuo R, Morihara H, Mohri T, Murasawa S, Takewaki K, Nakayama H, et al. The inhibition of N-glycosylation of glycoprotein 130 molecule abolishes STAT3 activation by IL-6 family cytokines in cultured cardiac myocytes. PLoS ONE. 2014;9:e111097 pubmed publisher |
| Boin A, Couvelard A, Couderc C, Brito I, Filipescu D, Kalamarides M, et al. Proteomic screening identifies a YAP-driven signaling network linked to tumor cell proliferation in human schwannomas. Neuro Oncol. 2014;16:1196-209 pubmed publisher |
- western blot; human; 1:1000; fig s1
| Ng Y, Lee J, Supko K, Khan A, Torres S, Berwick M, et al. Pan-erbB inhibition potentiates BRAF inhibitors for melanoma treatment. Melanoma Res. 2014;24:207-18 pubmed publisher |
- western blot; human; fig 4
| Kodama T, Motoi N, Ninomiya H, Sakamoto H, Kitada K, Tsukaguchi T, et al. A novel mechanism of EML4-ALK rearrangement mediated by chromothripsis in a patient-derived cell line. J Thorac Oncol. 2014;9:1638-46 pubmed publisher |
| Kim K, Kim G, Kim J, Yun H, Lim S, Choi H. Interleukin-22 promotes epithelial cell transformation and breast tumorigenesis via MAP3K8 activation. Carcinogenesis. 2014;35:1352-61 pubmed publisher |
- immunohistochemistry; mouse; 1:1000
| Borg M, Andrews Z, Watt M. Exercise training does not enhance hypothalamic responsiveness to leptin or ghrelin in male mice. J Neuroendocrinol. 2014;26:68-79 pubmed publisher |
| Sackmann-Sala L, Chiche A, Mosquera-Garrote N, Boutillon F, Cordier C, Pourmir I, et al. Prolactin-induced prostate tumorigenesis links sustained Stat5 signaling with the amplification of basal/stem cells and emergence of putative luminal progenitors. Am J Pathol. 2014;184:3105-19 pubmed publisher |
| Kodama T, Tsukaguchi T, Yoshida M, Kondoh O, Sakamoto H. Selective ALK inhibitor alectinib with potent antitumor activity in models of crizotinib resistance. Cancer Lett. 2014;351:215-21 pubmed publisher |
- western blot; mouse; 1:1000
| Bhaskar K, Maphis N, Xu G, Varvel N, Kokiko-Cochran O, Weick J, et al. Microglial derived tumor necrosis factor-α drives Alzheimer's disease-related neuronal cell cycle events. Neurobiol Dis. 2014;62:273-85 pubmed publisher |
| Waitkus M, Chandrasekharan U, Willard B, Tee T, Hsieh J, Przybycin C, et al. Signal integration and gene induction by a functionally distinct STAT3 phosphoform. Mol Cell Biol. 2014;34:1800-11 pubmed publisher |
- western blot; mouse; 1:1000; fig 4d
| Zhang H, Hu H, Greeley N, Jin J, Matthews A, Ohashi E, et al. STAT3 restrains RANK- and TLR4-mediated signalling by suppressing expression of the E2 ubiquitin-conjugating enzyme Ubc13. Nat Commun. 2014;5:5798 pubmed publisher |
- chromatin immunoprecipitation; human
- western blot; human; 1:10000
| Xiang M, Birkbak N, Vafaizadeh V, Walker S, Yeh J, Liu S, et al. STAT3 induction of miR-146b forms a feedback loop to inhibit the NF-κB to IL-6 signaling axis and STAT3-driven cancer phenotypes. Sci Signal. 2014;7:ra11 pubmed publisher |
| Smith I, Godinez G, Singh B, McCaughey K, Alcantara R, Gururaja T, et al. Inhibition of Janus kinase signaling during controlled mechanical ventilation prevents ventilation-induced diaphragm dysfunction. FASEB J. 2014;28:2790-803 pubmed publisher |
- immunohistochemistry; mouse; 1:3,000
| Gautron L, Cravo R, Elmquist J, Elias C. Discrete melanocortin-sensitive neuroanatomical pathway linking the ventral premmamillary nucleus to the paraventricular hypothalamus. Neuroscience. 2013;240:70-82 pubmed publisher |
| Ren F, Su F, Ning H, Wang Y, Geng Y, Feng Y, et al. SIPAR negatively regulates STAT3 signaling and inhibits progression of melanoma. Cell Signal. 2013;25:2272-80 pubmed publisher |
| Scott M, Lachey J, Sternson S, Lee C, Elias C, Friedman J, et al. Leptin targets in the mouse brain. J Comp Neurol. 2009;514:518-32 pubmed publisher |
| Stairs D, Bayne L, Rhoades B, Vega M, Waldron T, Kalabis J, et al. Deletion of p120-catenin results in a tumor microenvironment with inflammation and cancer that establishes it as a tumor suppressor gene. Cancer Cell. 2011;19:470-83 pubmed publisher |
| Fiedler J, Strauss G, Wannack M, Schwiebert S, Seidel K, Henning K, et al. Two patterns of thrombopoietin signaling suggest no coupling between platelet production and thrombopoietin reactivity in thrombocytopenia-absent radii syndrome. Haematologica. 2012;97:73-81 pubmed publisher |
| Zhang W, Wang L, Wang Q, Luo X, Fang D, Chen Y, et al. CUEDC2 (CUE domain-containing 2) and SOCS3 (suppressors of cytokine signaling 3) cooperate to negatively regulate Janus kinase 1/signal transducers and activators of transcription 3 signaling. J Biol Chem. 2012;287:382-92 pubmed publisher |
| Lee S, Bookout A, Lee C, Gautron L, Harper M, Elias C, et al. Laser-capture microdissection and transcriptional profiling of the dorsomedial nucleus of the hypothalamus. J Comp Neurol. 2012;520:3617-32 pubmed publisher |
| Marotta L, Almendro V, Marusyk A, Shipitsin M, Schemme J, Walker S, et al. The JAK2/STAT3 signaling pathway is required for growth of CD44⁺CD24⁻ stem cell-like breast cancer cells in human tumors. J Clin Invest. 2011;121:2723-35 pubmed publisher |
