product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Ki-67 (D3B5) Rabbit mAb
catalog :
9129
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D3B5
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 45
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 2a
Pi xf1 eiro Hermida S, Mart xed nez P, Bosso G, Flores J, Saraswati S, Connor J, et al. Consequences of telomere dysfunction in fibroblasts, club and basal cells for lung fibrosis development. Nat Commun. 2022;13:5656 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 2c
Pascal L, Igarashi T, Mizoguchi S, Chen W, Rigatti L, Madigan C, et al. E-cadherin deficiency promotes prostate macrophage inflammation and bladder overactivity in aged male mice. Aging (Albany NY). 2022;14:2945-2965 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:2000; loading ...; fig 1f
Khadka P, Reitman Z, Lu S, Buchan G, Gionet G, Dubois F, et al. PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation. Nat Commun. 2022;13:604 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:400; loading ...; fig 2c
Heitink L, Whittle J, Vaillant F, Capaldo B, Dekkers J, Dawson C, et al. In vivo genome-editing screen identifies tumor suppressor genes that cooperate with Trp53 loss during mammary tumorigenesis. Mol Oncol. 2022;16:1119-1131 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 3d
Saha J, Bae J, Wang S, Lu H, Chappell L, Gopal P, et al. Ablating putative Ku70 phosphorylation sites results in defective DNA damage repair and spontaneous induction of hepatocellular carcinoma. Nucleic Acids Res. 2021;49:9836-9850 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 3a
Pal S, Nixon B, Glennon M, Shridhar P, Satterfield S, Su Y, et al. Replication Stress Response Modifies Sarcomeric Cardiomyopathy Remodeling. J Am Heart Assoc. 2021;10:e021768 pubmed publisher
  • immunocytochemistry; mouse; 1:500; loading ...; fig 2b
Yang S, Qu Y, Chen J, Chen S, Sun L, Zhou Y, et al. Bee Pollen Polysaccharide From Rosa rugosa Thunb. (Rosaceae) Promotes Pancreatic β-Cell Proliferation and Insulin Secretion. Front Pharmacol. 2021;12:688073 pubmed publisher
  • immunohistochemistry; mouse; 1:50; loading ...; fig 4a
Piñeiro Hermida S, Martinez P, Blasco M. Short and dysfunctional telomeres protect from allergen-induced airway inflammation. Aging Cell. 2021;20:e13352 pubmed publisher
  • immunohistochemistry; mouse; 1:400; loading ...; fig 4c
Ezan J, Moreau M, Mamo T, Shimbo M, Decroo M, Richter M, et al. Early loss of Scribble affects cortical development, interhemispheric connectivity and psychomotor activity. Sci Rep. 2021;11:9106 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig s2c
Phan T, Schink L, Mann J, Merk V, Zwicky P, Mundt S, et al. Keratinocytes control skin immune homeostasis through de novo-synthesized glucocorticoids. Sci Adv. 2021;7: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:400; loading ...; fig 6i
Break T, Oikonomou V, Dutzan N, Desai J, Swidergall M, Freiwald T, et al. Aberrant type 1 immunity drives susceptibility to mucosal fungal infections. Science. 2021;371: pubmed publisher
  • immunocytochemistry; mouse; 1:500; fig s6f
Yang J, Kitami M, Pan H, Nakamura M, Zhang H, Liu F, et al. Augmented BMP signaling commits cranial neural crest cells to a chondrogenic fate by suppressing autophagic β-catenin degradation. Sci Signal. 2021;14: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:400; loading ...; fig 6a
Chiremba T, Neufeld K. Constitutive Musashi1 expression impairs mouse postnatal development and intestinal homeostasis. Mol Biol Cell. 2021;32:28-44 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 4a
Atkins A, Xu M, Li M, Rogers N, Pryzhkova M, Jordan P. SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis. elife. 2020;9: pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 4c
Stupnikov M, Yang Y, Mori M, LU J, Cardoso W. Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation. elife. 2019;8: pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 3e
Yin M, Zhou H, Lin C, Long L, Yang X, Zhang H, et al. CD34+KLF4+ Stromal Stem Cells Contribute to Endometrial Regeneration and Repair. Cell Rep. 2019;27:2709-2724.e3 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig s2k
Lee J, Stone M, Porrett P, Thomas S, Komar C, Li J, et al. Hepatocytes direct the formation of a pro-metastatic niche in the liver. Nature. 2019;567:249-252 pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; fig 5a
Guillon J, Petit C, Moreau M, Toutain B, Henry C, Roche H, et al. Regulation of senescence escape by TSP1 and CD47 following chemotherapy treatment. Cell Death Dis. 2019;10:199 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 5a
Pan W, Moroishi T, Koo J, Guan K. Cell type-dependent function of LATS1/2 in cancer cell growth. Oncogene. 2019;38:2595-2610 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 6a
Xie H, Wang Y, Zhang H, Fan Q, Dai D, Zhuang L, et al. Tubular epithelial C1orf54 mediates protection and recovery from acute kidney injury. J Cell Mol Med. 2018;22:4985-4996 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig s6a
  • western blot; mouse; loading ...; fig s6c
Miyamoto Y, Torii T, Tago K, Tanoue A, Takashima S, Yamauchi J. BIG1/Arfgef1 and Arf1 regulate the initiation of myelination by Schwann cells in mice. Sci Adv. 2018;4:eaar4471 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 1e
Fu X, Khalil H, Kanisicak O, Boyer J, Vagnozzi R, Maliken B, et al. Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart. J Clin Invest. 2018;128:2127-2143 pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; fig 5a
Pleiner T, Bates M, Gorlich D. A toolbox of anti-mouse and anti-rabbit IgG secondary nanobodies. J Cell Biol. 2018;217:1143-1154 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig s2b
Niu X, Pi S, Baral S, Xia Y, He Q, Li Y, et al. P2Y12 Promotes Migration of Vascular Smooth Muscle Cells Through Cofilin Dephosphorylation During Atherogenesis. Arterioscler Thromb Vasc Biol. 2017;37:515-524 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:400; loading ...; fig 5a
Bosch P, Fuller L, Sleeth C, Weiner J. Akirin2 is essential for the formation of the cerebral cortex. Neural Dev. 2016;11:21 pubmed
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 4c
Zhou L, Dai H, Wu J, Zhou M, Yuan H, Du J, et al. Role of FEN1 S187 phosphorylation in counteracting oxygen-induced stress and regulating postnatal heart development. FASEB J. 2017;31:132-147 pubmed publisher
  • flow cytometry; human; 1:200; fig 4
  • immunocytochemistry; human
Titmarsh D, Glass N, Mills R, Hidalgo A, Wolvetang E, Porrello E, et al. Induction of Human iPSC-Derived Cardiomyocyte Proliferation Revealed by Combinatorial Screening in High Density Microbioreactor Arrays. Sci Rep. 2016;6:24637 pubmed publisher
  • immunocytochemistry; human; fig 4
Lalli M, Jang J, Park J, Wang Y, Guzman E, Zhou H, et al. Haploinsufficiency of BAZ1B contributes to Williams syndrome through transcriptional dysregulation of neurodevelopmental pathways. Hum Mol Genet. 2016;25:1294-306 pubmed publisher
  • immunohistochemistry; mouse; 1:400; fig 4
Zhang Y, Fan J, Ho J, Hu T, Kneeland S, Fan X, et al. Crim1 regulates integrin signaling in murine lens development. Development. 2016;143:356-66 pubmed publisher
  • immunocytochemistry; human; 1:400; fig 7a
Massey A. Multiparametric Cell Cycle Analysis Using the Operetta High-Content Imager and Harmony Software with PhenoLOGIC. PLoS ONE. 2015;10:e0134306 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 1f
Salvucci O, Ohnuki H, Maric D, Hou X, Li X, Yoon S, et al. EphrinB2 controls vessel pruning through STAT1-JNK3 signalling. Nat Commun. 2015;6:6576 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Kitajima S, Kohno S, Kondoh A, Sasaki N, Nishimoto Y, Li F, et al. Undifferentiated State Induced by Rb-p53 Double Inactivation in Mouse Thyroid Neuroendocrine Cells and Embryonic Fibroblasts. Stem Cells. 2015;33:1657-69 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; fig s9
Eikawa S, Nishida M, Mizukami S, Yamazaki C, Nakayama E, Udono H. Immune-mediated antitumor effect by type 2 diabetes drug, metformin. Proc Natl Acad Sci U S A. 2015;112:1809-14 pubmed publisher
  • immunocytochemistry; human; fig 2
Kocher B, White L, Piwnica Worms D. DAPK3 suppresses acini morphogenesis and is required for mouse development. Mol Cancer Res. 2015;13:358-67 pubmed publisher
Feng T, Dzieran J, Yuan X, Dropmann A, Maass T, Teufel A, et al. Hepatocyte-specific Smad7 deletion accelerates DEN-induced HCC via activation of STAT3 signaling in mice. Oncogenesis. 2017;6:e294 pubmed publisher
Lee J, Harris A, Holley C, Mahadevan J, Pyles K, Lavagnino Z, et al. Rpl13a small nucleolar RNAs regulate systemic glucose metabolism. J Clin Invest. 2016;126:4616-4625 pubmed publisher
Guan J, Tucker E, Wan H, Chand D, Danielson L, Ruuth K, et al. The ALK inhibitor PF-06463922 is effective as a single agent in neuroblastoma driven by expression of ALK and MYCN. Dis Model Mech. 2016;9:941-52 pubmed publisher
Zhao Y, Tu M, Wang W, Qiu J, Yu A, Yu A. Genetically engineered pre-microRNA-34a prodrug suppresses orthotopic osteosarcoma xenograft tumor growth via the induction of apoptosis and cell cycle arrest. Sci Rep. 2016;6:26611 pubmed publisher
Welker A, Jaros B, Puduvalli V, Imitola J, Kaur B, Beattie C. Standardized orthotopic xenografts in zebrafish reveal glioma cell-line-specific characteristics and tumor cell heterogeneity. Dis Model Mech. 2016;9:199-210 pubmed publisher
Yang L, Gu S, Ye W, Song Y, Chen Y. Augmented Indian hedgehog signaling in cranial neural crest cells leads to craniofacial abnormalities and dysplastic temporomandibular joint in mice. Cell Tissue Res. 2016;364:105-15 pubmed publisher
Holik A, Filby C, Pasquet J, Viitaniemi K, Ciciulla J, Sutherland K, et al. The LIM-domain only protein 4 contributes to lung epithelial cell proliferation but is not essential for tumor progression. Respir Res. 2015;16:67 pubmed publisher
Venkatraman G, Benesch M, Tang X, Dewald J, McMullen T, Brindley D. Lysophosphatidate signaling stabilizes Nrf2 and increases the expression of genes involved in drug resistance and oxidative stress responses: implications for cancer treatment. FASEB J. 2015;29:772-85 pubmed publisher
Andl T, Le Bras G, Richards N, Allison G, Loomans H, Washington M, et al. Concerted loss of TGFβ-mediated proliferation control and E-cadherin disrupts epithelial homeostasis and causes oral squamous cell carcinoma. Carcinogenesis. 2014;35:2602-10 pubmed publisher
Panopoulos A, Pacios Bras C, Choi J, Yenjerla M, Sussman M, Fotedar R, et al. Failure of cell cleavage induces senescence in tetraploid primary cells. Mol Biol Cell. 2014;25:3105-18 pubmed publisher
Engels M, Rajarajan K, Feistritzer R, Sharma A, Nielsen U, Schalij M, et al. Insulin-like growth factor promotes cardiac lineage induction in vitro by selective expansion of early mesoderm. Stem Cells. 2014;32:1493-502 pubmed publisher
product information
SKU :
9129S
Product-Name :
Ki-67 (D3B5) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R
Applications :
Flow cytometry
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
Host :
Rabbit
Target :
KI-67
Primary-Protein :
KI-67
Alt-Names :
Antigen KI-67,KI67,KIA,MKI67,antigen identified by monoclonal antibody Ki-67,proliferation-related Ki-67 antigen
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.