product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Blimp-1/PRDI-BF1 (C14A4) Rabbit mAb
catalog :
9115
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
C14A4
reactivity :
human, mouse
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry
more info or order :
Cell Signaling Technology product webpage
citations: 21
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...
Ladle B, Li K, Phillips M, Pucsek A, Haile A, Powell J, et al. De novo DNA methylation by DNA methyltransferase 3a controls early effector CD8+ T-cell fate decisions following activation. Proc Natl Acad Sci U S A. 2016;113:10631-6 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4n
Kim G, Das R, Goduni L, McClellan S, Hazlett L, Mahabeleshwar G. Kruppel-like Factor 6 Promotes Macrophage-mediated Inflammation by Suppressing B Cell Leukemia/Lymphoma 6 Expression. J Biol Chem. 2016;291:21271-21282 pubmed
  • western blot; human; loading ...; fig 4e
Weiss J, Chen W, Nyuydzefe M, Trzeciak A, Flynn R, Tonra J, et al. ROCK2 signaling is required to induce a subset of T follicular helper cells through opposing effects on STATs in autoimmune settings. Sci Signal. 2016;9:ra73 pubmed publisher
  • western blot; human; fig 5
Gunasekharan V, Li Y, Andrade J, Laimins L. Post-Transcriptional Regulation of KLF4 by High-Risk Human Papillomaviruses Is Necessary for the Differentiation-Dependent Viral Life Cycle. PLoS Pathog. 2016;12:e1005747 pubmed publisher
  • immunocytochemistry; human; fig 3
Kushwaha R, Jagadish N, Kustagi M, Mendiratta G, Seandel M, Soni R, et al. Mechanism and Role of SOX2 Repression in Seminoma: Relevance to Human Germline Specification. Stem Cell Reports. 2016;6:772-783 pubmed publisher
  • western blot; mouse; fig 7
Cao J, Zhang X, Wang Q, Qiu G, Hou C, Wang J, et al. Smad4 represses the generation of memory-precursor effector T cells but is required for the differentiation of central memory T cells. Cell Death Dis. 2015;6:e1984 pubmed publisher
  • western blot; human; 1:1000; fig 8
Nawandar D, Wang A, Makielski K, Lee D, Ma S, Barlow E, et al. Differentiation-Dependent KLF4 Expression Promotes Lytic Epstein-Barr Virus Infection in Epithelial Cells. PLoS Pathog. 2015;11:e1005195 pubmed publisher
  • western blot; mouse; fig 6
Rozanski C, Utley A, Carlson L, Farren M, Murray M, Russell L, et al. CD28 Promotes Plasma Cell Survival, Sustained Antibody Responses, and BLIMP-1 Upregulation through Its Distal PYAP Proline Motif. J Immunol. 2015;194:4717-28 pubmed publisher
  • flow cytometry; human; 1:100; fig 1c
Sugawa F, Araúzo Bravo M, Yoon J, Kim K, Aramaki S, Wu G, et al. Human primordial germ cell commitment in vitro associates with a unique PRDM14 expression profile. EMBO J. 2015;34:1009-24 pubmed publisher
Fang F, Angulo B, Xia N, Sukhwani M, Wang Z, Carey C, et al. A PAX5-OCT4-PRDM1 developmental switch specifies human primordial germ cells. Nat Cell Biol. 2018;20:655-665 pubmed publisher
McHugh D, Caduff N, Barros M, Rämer P, Raykova A, Murer A, et al. Persistent KSHV Infection Increases EBV-Associated Tumor Formation In Vivo via Enhanced EBV Lytic Gene Expression. Cell Host Microbe. 2017;22:61-73.e7 pubmed publisher
Kraus R, Yu X, Cordes B, Sathiamoorthi S, Iempridee T, Nawandar D, et al. Hypoxia-inducible factor-1α plays roles in Epstein-Barr virus's natural life cycle and tumorigenesis by inducing lytic infection through direct binding to the immediate-early BZLF1 gene promoter. PLoS Pathog. 2017;13:e1006404 pubmed publisher
Nawandar D, Ohashi M, Djavadian R, Barlow E, Makielski K, Ali A, et al. Differentiation-Dependent LMP1 Expression Is Required for Efficient Lytic Epstein-Barr Virus Reactivation in Epithelial Cells. J Virol. 2017;91: pubmed publisher
Wang H, Xiang J, Zhang W, Li J, Wei Q, Zhong L, et al. Induction of Germ Cell-like Cells from Porcine Induced Pluripotent Stem Cells. Sci Rep. 2016;6:27256 pubmed publisher
Liang L, Zhang Z, Wang Y, Nong L, Zheng Y, Qu L, et al. The Genetic Deletion of 6q21 and PRDM1 and Clinical Implications in Extranodal NK/T Cell Lymphoma, Nasal Type. Biomed Res Int. 2015;2015:435423 pubmed publisher
Park Min K, Lim E, Lee M, Park S, Giannopoulou E, Yarilina A, et al. Inhibition of osteoclastogenesis and inflammatory bone resorption by targeting BET proteins and epigenetic regulation. Nat Commun. 2014;5:5418 pubmed publisher
Liang L, Nong L, Zhang S, Zhao J, Ti H, Dong Y, et al. The downregulation of PRDM1/Blimp-1 is associated with aberrant expression of miR-223 in extranodal NK/T-cell lymphoma, nasal type. J Exp Clin Cancer Res. 2014;33:7 pubmed publisher
Liu B, Stoop J, Huizinga T, Toes R. IL-21 enhances the activity of the TLR-MyD88-STAT3 pathway but not the classical TLR-MyD88-NF-?B pathway in human B cells to boost antibody production. J Immunol. 2013;191:4086-94 pubmed publisher
Cubedo E, Maurin M, Jiang X, Lossos I, Wright K. PRDM1/Blimp1 downregulates expression of germinal center genes LMO2 and HGAL. FEBS J. 2011;278:3065-75 pubmed publisher
Smith M, Maurin M, Cho H, Becknell B, Freud A, Yu J, et al. PRDM1/Blimp-1 controls effector cytokine production in human NK cells. J Immunol. 2010;185:6058-67 pubmed publisher
Desai S, Maurin M, Smith M, Bolick S, Dessureault S, Tao J, et al. PRDM1 is required for mantle cell lymphoma response to bortezomib. Mol Cancer Res. 2010;8:907-18 pubmed publisher
product information
SKU :
9115S
Product-Name :
Blimp-1/PRDI-BF1 (C14A4) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, (Mk)
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
95-100
Host :
Rabbit
Target :
PRD1
Primary-Protein :
PRDM1
Alt-Names :
B-lymphocyte-induced maturation protein 1,BLIMP-1,BLIMP1,Beta-interferon gene positive regulatory domain I-binding factor,MGC118922,MGC118923,MGC118924,MGC118925,PR domain containing 1, with ZNF domain,PR domain zinc finger protein 1,PR domain-containing protein 1,PR-domain zinc finger protein 1,PRDI-BF1,PRDI-binding factor 1,PRDI-binding factor-1,PRDM1,Positive regulatory domain I-binding factor 1,beta-interferon gene positive-regulatory domain I binding factor
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.