product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-cdc2 (Tyr15) Antibody
catalog :
9111L
quantity :
300 ul
price :
658 USD
clonality :
polyclonal
host :
rabbit
antigen modification :
phosphorylated
reactivity :
African green monkey, human, mouse, rat
application :
western blot, ELISA, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 16
Published Application/Species/DilutionReference
  • western blot; mouse; 1:500; fig 3
Brosh R, Hrynyk I, Shen J, Waghray A, Zheng N, Lemischka I. A dual molecular analogue tuner for dissecting protein function in mammalian cells. Nat Commun. 2016;7:11742 pubmed publisher
  • western blot; human; fig 5
Chen X, Stauffer S, Chen Y, Dong J. Ajuba Phosphorylation by CDK1 Promotes Cell Proliferation and Tumorigenesis. J Biol Chem. 2016;: pubmed
  • western blot; mouse; fig s3
Diril M, Bisteau X, Kitagawa M, Caldez M, Wee S, Gunaratne J, et al. Loss of the Greatwall Kinase Weakens the Spindle Assembly Checkpoint. PLoS Genet. 2016;12:e1006310 pubmed publisher
  • western blot; human; fig 5
Zhang M, Linghu E, Zhan Q, He T, Cao B, Brock M, et al. Methylation of DACT2 accelerates esophageal cancer development by activating Wnt signaling. Oncotarget. 2016;7:17957-69 pubmed publisher
  • western blot; mouse; 1:1000
Sun D, Buttitta L. Protein phosphatase 2A promotes the transition to G0 during terminal differentiation in Drosophila. Development. 2015;142:3033-45 pubmed publisher
  • western blot; human
  • western blot; mouse
Vassilopoulos A, Tominaga Y, Kim H, Lahusen T, Li B, Yu H, et al. WEE1 murine deficiency induces hyper-activation of APC/C and results in genomic instability and carcinogenesis. Oncogene. 2015;34:3023-35 pubmed publisher
  • western blot; human
Li X, Liang Q, Liu W, Zhang N, Xu L, Zhang X, et al. Ras association domain family member 10 suppresses gastric cancer growth by cooperating with GSTP1 to regulate JNK/c-Jun/AP-1 pathway. Oncogene. 2015;: pubmed publisher
  • western blot; human; 1:1000
Zanotto-Filho A, Braganhol E, Klafke K, Figueiró F, Terra S, Paludo F, et al. Autophagy inhibition improves the efficacy of curcumin/temozolomide combination therapy in glioblastomas. Cancer Lett. 2015;358:220-31 pubmed publisher
  • western blot; human
Pattabiraman C, Hong S, Gunasekharan V, Pranatharthi A, Bajaj J, Srivastava S, et al. CD66+ cells in cervical precancers are partially differentiated progenitors with neoplastic traits. Cancer Res. 2014;74:6682-92 pubmed publisher
  • western blot; human
de Graaf E, Kaplon J, Zhou H, Heck A, Peeper D, Altelaar A. Phosphoproteome dynamics in onset and maintenance of oncogene-induced senescence. Mol Cell Proteomics. 2014;13:2089-100 pubmed publisher
  • western blot; African green monkey
Kobayashi H, Saito T, Sato K, Furusawa K, Hosokawa T, Tsutsumi K, et al. Phosphorylation of cyclin-dependent kinase 5 (Cdk5) at Tyr-15 is inhibited by Cdk5 activators and does not contribute to the activation of Cdk5. J Biol Chem. 2014;289:19627-36 pubmed publisher
  • western blot; human; fig s9
Kim M, Kim M, Lee M, Kim C, Lim D. The MST1/2-SAV1 complex of the Hippo pathway promotes ciliogenesis. Nat Commun. 2014;5:5370 pubmed publisher
  • western blot; mouse; fig 4
Diril M, Ratnacaram C, Padmakumar V, Du T, Wasser M, Coppola V, et al. Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration. Proc Natl Acad Sci U S A. 2012;109:3826-31 pubmed publisher
Chang S, Chang C, Lee D, Lee P, Yeh Y, Yeh C, et al. Tumor cell cycle arrest induced by shear stress: Roles of integrins and Smad. Proc Natl Acad Sci U S A. 2008;105:3927-32 pubmed publisher
Ma D, Yu H, Lin D, Sun Y, Liu L, Liu Y, et al. S6K1 is involved in polyploidization through its phosphorylation at Thr421/Ser424. J Cell Physiol. 2009;219:31-44 pubmed publisher
Bartucci M, Svensson S, Romania P, Dattilo R, Patrizii M, Signore M, et al. Therapeutic targeting of Chk1 in NSCLC stem cells during chemotherapy. Cell Death Differ. 2012;19:768-78 pubmed publisher
product information
SKU :
9111L
Product-Name :
Phospho-cdc2 (Tyr15) Antibody
Size :
300 ul
Price-(USD) :
658 USD
Species-x-Reactivity :
H, M, R, Mk, Dm, X
Applications :
Immunoprecipitation
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
34
Host :
Rabbit
Target :
Cdc2 (Tyr15) phosphate
Primary-Protein :
CDK1
Alt-Names :
CDC2,CDC28A,CDK1,Cell division control protein 2 homolog,Cyclin-dependent kinase 1,DKFZp686L20222,MGC111195,P34CDC2,cell cycle controller CDC2,cell division cycle 2,cell division cycle 2, G1 to S and G2 to M,p34 protein kinase
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.