product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
p44/42 MAPK (Erk1/2) (3A7) Mouse mAb
catalog :
9107S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
mouse
clone name :
3A7
reactivity :
least shrew, human, mouse, rat
application :
western blot
more info or order :
Cell Signaling Technology product webpage
citations: 14
Published Application/Species/DilutionReference
  • western blot (knockdown validation); human; fig 3
Hensel J, Duex J, Owens C, Dancik G, Edwards M, Frierson H, et al. Patient Mutation Directed shRNA Screen Uncovers Novel Bladder Tumor Growth Suppressors. Mol Cancer Res. 2015;13:1306-15 pubmed publisher
  • western blot; human
Picot N, Guerrette R, Beauregard A, Jean S, Michaud P, Harquail J, et al. Mammaglobin 1 promotes breast cancer malignancy and confers sensitivity to anticancer drugs. Mol Carcinog. 2016;55:1150-62 pubmed publisher
  • western blot; human; 1:1000; fig 6
Verbrugge S, Al M, Assaraf Y, Kammerer S, Chandrupatla D, Honeywell R, et al. Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival activation ERK/Akt/mTOR. Oncotarget. 2016;7:5240-57 pubmed publisher
  • western blot; human; 1:1000
Carthy J, Sundqvist A, Heldin A, van Dam H, Kletsas D, Heldin C, et al. Tamoxifen Inhibits TGF-β-Mediated Activation of Myofibroblasts by Blocking Non-Smad Signaling Through ERK1/2. J Cell Physiol. 2015;230:3084-92 pubmed publisher
  • western blot; rat; fig 6e
Pedros C, Gaud G, Bernard I, Kassem S, Chabod M, Lagrange D, et al. An Epistatic Interaction between Themis1 and Vav1 Modulates Regulatory T Cell Function and Inflammatory Bowel Disease Development. J Immunol. 2015;195:1608-16 pubmed publisher
  • western blot; mouse; 1:1000
Niu F, Yao H, Zhang W, Sutliff R, Buch S. Tat 101-mediated enhancement of brain pericyte migration involves platelet-derived growth factor subunit B homodimer: implications for human immunodeficiency virus-associated neurocognitive disorders. J Neurosci. 2014;34:11812-25 pubmed publisher
  • western blot; human; 1:1000; fig 4
Lin C, Chen P, Hsu L, Kuo D, Chu S, Hsieh Y. Inhibition of the invasion and migration of renal carcinoma 786‑o‑si3 cells in vitro and in vivo by Koelreuteria formosana extract. Mol Med Rep. 2014;10:3334-42 pubmed publisher
  • western blot; human; 1:1000
Pourreyron C, Chen M, McGrath J, Salas-Alanis J, South A, Leigh I. High levels of type VII collagen expression in recessive dystrophic epidermolysis bullosa cutaneous squamous cell carcinoma keratinocytes increases PI3K and MAPK signalling, cell migration and invasion. Br J Dermatol. 2014;170:1256-65 pubmed publisher
  • western blot; least shrew
Alkam T, Chebolu S, Darmani N. Cyclophosphamide causes activation of protein kinase A (PKA) in the brainstem of vomiting least shrews (Cryptotis parva). Eur J Pharmacol. 2014;722:156-64 pubmed
  • western blot; rat; 1:1000
Patki G, Solanki N, Atrooz F, Ansari A, Allam F, Jannise B, et al. Novel mechanistic insights into treadmill exercise based rescue of social defeat-induced anxiety-like behavior and memory impairment in rats. Physiol Behav. 2014;130:135-44 pubmed publisher
  • western blot; human
Yang Y, Li J, Pan X, Zhou P, Yu X, Cao H, et al. Co-culture with mesenchymal stem cells enhances metabolic functions of liver cells in bioartificial liver system. Biotechnol Bioeng. 2013;110:958-68 pubmed publisher
  • western blot; human
Abbonante V, Gruppi C, Rubel D, Gross O, Moratti R, Balduini A. Discoidin domain receptor 1 protein is a novel modulator of megakaryocyte-collagen interactions. J Biol Chem. 2013;288:16738-46 pubmed publisher
Pereira M, Martynhak B, Andreatini R, Svenningsson P. 5-HT6 receptor agonism facilitates emotional learning. Front Pharmacol. 2015;6:200 pubmed publisher
Fonseca B, Alain T, Finestone L, Huang B, Rolfe M, Jiang T, et al. Pharmacological and genetic evaluation of proposed roles of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK), extracellular signal-regulated kinase (ERK), and p90(RSK) in the control of mTORC1 protein signaling by phorbo. J Biol Chem. 2011;286:27111-22 pubmed publisher
product information
SKU :
9107S
Product-Name :
p44/42 MAPK (Erk1/2) (3A7) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Hm, Mk, Mi, Z, B, Pg
Applications :
Western blot
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
42, 44
Host :
Mouse
Target :
ERK1/ERK2
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.