product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
IκBα (L35A5) Mouse mAb (Amino-terminal Antigen) (Alexa Fluor® 647 Conjugate)
catalog :
8993
clonality :
monoclonal
host :
mouse
conjugate :
AF647
clone name :
L35A5
reactivity :
human, mouse, rat, cow
application :
flow cytometry
citations: 13
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; fig 5
Pannu J, Belle J, Förster M, Duerr C, Shen S, Kane L, et al. Ubiquitin specific protease 21 is dispensable for normal development, hematopoiesis and lymphocyte differentiation. PLoS ONE. 2015;10:e0117304 pubmed publisher
Tavares R, Pathak S. Helicobacter pylori protein JHP0290 exhibits proliferative and anti-apoptotic effects in gastric epithelial cells. PLoS ONE. 2015;10:e0124407 pubmed publisher
Shoda T, Futamura K, Kobayashi F, Saito H, Matsumoto K, Matsuda A. Expression of thymus and activation-regulated chemokine (TARC) by human dermal cells, but not epidermal keratinocytes. J Dermatol Sci. 2014;76:90-5 pubmed publisher
Beswick E, Johnson J, Saada J, Humen M, House J, Dann S, et al. TLR4 activation enhances the PD-L1-mediated tolerogenic capacity of colonic CD90+ stromal cells. J Immunol. 2014;193:2218-29 pubmed publisher
Wong S, Chan S, Wong W, Wong P, Lai M. Andrographolide attenuates interleukin-1?-stimulated upregulation of chemokine CCL5 and glial fibrillary acidic protein in astrocytes. Neuroreport. 2014;25:881-6 pubmed publisher
Meeker S, Seamons A, Paik J, Treuting P, Brabb T, Grady W, et al. Increased dietary vitamin D suppresses MAPK signaling, colitis, and colon cancer. Cancer Res. 2014;74:4398-408 pubmed publisher
Dedoni S, Olianas M, Ingianni A, Onali P. Type I interferons up-regulate the expression and signalling of p75 NTR/TrkA receptor complex in differentiated human SH-SY5Y neuroblastoma cells. Neuropharmacology. 2014;79:321-34 pubmed publisher
Nomura J, Busso N, Ives A, Tsujimoto S, Tamura M, So A, et al. Febuxostat, an inhibitor of xanthine oxidase, suppresses lipopolysaccharide-induced MCP-1 production via MAPK phosphatase-1-mediated inactivation of JNK. PLoS ONE. 2013;8:e75527 pubmed publisher
Ma C, Zuo W, Wang X, Wei L, Guo Q, Song X. Lapatinib inhibits the activation of NF-?B through reducing phosphorylation of I?B-? in breast cancer cells. Oncol Rep. 2013;29:812-8 pubmed publisher
Sugimoto J, ROMANI A, Valentin Torres A, Luciano A, Ramirez Kitchen C, Funderburg N, et al. Magnesium decreases inflammatory cytokine production: a novel innate immunomodulatory mechanism. J Immunol. 2012;188:6338-46 pubmed publisher
Kuiken H, Egan D, Laman H, Bernards R, Beijersbergen R, Dirac A. Identification of F-box only protein 7 as a negative regulator of NF-kappaB signalling. J Cell Mol Med. 2012;16:2140-9 pubmed publisher
Chattopadhyay M, Kodela R, Nath N, Barsegian A, Boring D, Kashfi K. Hydrogen sulfide-releasing aspirin suppresses NF-?B signaling in estrogen receptor negative breast cancer cells in vitro and in vivo. Biochem Pharmacol. 2012;83:723-32 pubmed publisher
Wu Y, Lousberg E, Moldenhauer L, Hayball J, Coller J, Rice K, et al. Inhibiting the TLR4-MyD88 signalling cascade by genetic or pharmacological strategies reduces acute alcohol-induced sedation and motor impairment in mice. Br J Pharmacol. 2012;165:1319-29 pubmed publisher
product information
SKU :
8993S
Product-Name :
IκBα (L35A5) Mouse mAb (Amino-terminal Antigen) (Alexa Fluor® 647 Conjugate)
Size :
100 ul
Price-(USD) :
291 USD
Species-x-Reactivity :
H, M, R, Mk, B, Pg, GP
Applications :
Flow cytometry
Product-Category :
Immunology and Inflammation
Shipping-Temp :
COLD
Storage-Temp :
4°C
Product-Type :
Monoclonal Antibody
Host :
Mouse
Target :
IkB-a
Primary-Protein :
IkB-alpha
Alt-Names :
I-kappa-B-alpha,IKBA,IkB-alpha,IkappaBalpha,MAD-3,MAD3,Major histocompatibility complex enhancer-binding protein MAD3,NF-kappa-B inhibitor alpha,NFKBI,NFKBIA,nuclear factor of kappa light chain gene enhancer in B-cells,nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.