| Reference |
|---|
Gebregiworgis T, Kano Y, St Germain J, Radulovich N, Udaskin M, Mentes A, et al. The Q61H mutation decouples KRAS from upstream regulation and renders cancer cells resistant to SHP2 inhibitors. Nat Commun. 2021;12:6274 pubmed publisher |
Vemulapalli V, Chylek L, Erickson A, Pfeiffer A, Gabriel K, LaRochelle J, et al. Time-resolved phosphoproteomics reveals scaffolding and catalysis-responsive patterns of SHP2-dependent signaling. elife. 2021;10: pubmed publisher |
Lonic A, Gehling F, Belle L, Li X, Schieber N, Nguyen E, et al. Phosphorylation of PKCδ by FER tips the balance from EGFR degradation to recycling. J Cell Biol. 2021;220: pubmed publisher |
Hernandez Valladares M, Aasebø E, Berven F, Selheim F, Bruserud Ø. Biological characteristics of aging in human acute myeloid leukemia cells: the possible importance of aldehyde dehydrogenase, the cytoskeleton and altered transcriptional regulation. Aging (Albany NY). 2020;12:24734-24777 pubmed publisher |
Chan K, Son S, Schmid E, Fletcher D. A viral fusogen hijacks the actin cytoskeleton to drive cell-cell fusion. elife. 2020;9: pubmed publisher |
Ahlers L, Trammell C, Carrell G, Mackinnon S, Torrevillas B, Chow C, et al. Insulin Potentiates JAK/STAT Signaling to Broadly Inhibit Flavivirus Replication in Insect Vectors. Cell Rep. 2019;29:1946-1960.e5 pubmed publisher |
Lundby A, Franciosa G, Emdal K, Refsgaard J, Gnosa S, Bekker Jensen D, et al. Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites. Cell. 2019;179:543-560.e26 pubmed publisher |
Tsarouhas V, Liu D, Tsikala G, Fedoseienko A, Zinn K, Matsuda R, et al. WASH phosphorylation balances endosomal versus cortical actin network integrities during epithelial morphogenesis. Nat Commun. 2019;10:2193 pubmed publisher |
Takashi Y, Kosako H, Sawatsubashi S, Kinoshita Y, Ito N, Tsoumpra M, et al. Activation of unliganded FGF receptor by extracellular phosphate potentiates proteolytic protection of FGF23 by its O-glycosylation. Proc Natl Acad Sci U S A. 2019;116:11418-11427 pubmed publisher |
Fearnley G, Young K, Edgar J, Antrobus R, Hay I, Liang W, et al. The homophilic receptor PTPRK selectively dephosphorylates multiple junctional regulators to promote cell-cell adhesion. elife. 2019;8: pubmed publisher |
Huang X, Gan G, Wang X, Xu T, Xie W. The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance. Autophagy. 2019;15:1258-1279 pubmed publisher |
Kano Y, Gebregiworgis T, Marshall C, Radulovich N, Poon B, St Germain J, et al. Tyrosyl phosphorylation of KRAS stalls GTPase cycle via alteration of switch I and II conformation. Nat Commun. 2019;10:224 pubmed publisher |
Zhou S, Appleman V, Rose C, Jun H, Yang J, Zhou Y, et al. Chronic platelet-derived growth factor receptor signaling exerts control over initiation of protein translation in glioma. Life Sci Alliance. 2018;1:e201800029 pubmed publisher |
Jun H, Appleman V, Wu H, Rose C, Pineda J, Yeo A, et al. A PDGFRα-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine. Nat Commun. 2018;9:3116 pubmed publisher |
Bakalar M, Joffe A, Schmid E, Son S, Podolski M, Fletcher D. Size-Dependent Segregation Controls Macrophage Phagocytosis of Antibody-Opsonized Targets. Cell. 2018;174:131-142.e13 pubmed publisher |
Chadwick M, Lane A, Thomas D, Smith A, White A, Davidson D, et al. Combined mTOR and MEK inhibition is an effective therapy in a novel mouse model for angiosarcoma. Oncotarget. 2018;9:24750-24765 pubmed publisher |
Chiang C, Tworak A, Kevany B, Xu B, Mayne J, Ning Z, et al. Quantitative phosphoproteomics reveals involvement of multiple signaling pathways in early phagocytosis by the retinal pigmented epithelium. J Biol Chem. 2017;292:19826-19839 pubmed publisher |
Diaz J, Morgan C, Minogue C, Hebert A, Coon J, Wells J. A Split-Abl Kinase for Direct Activation in Cells. Cell Chem Biol. 2017;24:1250-1258.e4 pubmed publisher |
Caruso J, Carruthers N, Shin N, Gill R, Stemmer P, ROSENSPIRE A. Mercury alters endogenous phosphorylation profiles of SYK in murine B cells. BMC Immunol. 2017;18:37 pubmed publisher |
Hawse W, Boggess W, Morel P. TCR Signal Strength Regulates Akt Substrate Specificity To Induce Alternate Murine Th and T Regulatory Cell Differentiation Programs. J Immunol. 2017;199:589-597 pubmed publisher |
Mohr S, Doebele C, Comoglio F, Berg T, Beck J, Bohnenberger H, et al. Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia. Cancer Cell. 2017;31:549-562.e11 pubmed publisher |
Reckel S, Hamelin R, Georgeon S, Armand F, Jolliet Q, Chiappe D, et al. Differential signaling networks of Bcr-Abl p210 and p190 kinases in leukemia cells defined by functional proteomics. Leukemia. 2017;31:1502-1512 pubmed publisher |
Saha A, O Connor R, Thangavelu G, Lovitch S, Dandamudi D, Wilson C, et al. Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality. J Clin Invest. 2016;126:2642-60 pubmed publisher |
Sprowl J, Ong S, Gibson A, Hu S, Du G, Lin W, et al. A phosphotyrosine switch regulates organic cation transporters. Nat Commun. 2016;7:10880 pubmed publisher |
Pinto S, Nirujogi R, Rojas P, Patil A, Manda S, Subbannayya Y, et al. Quantitative phosphoproteomic analysis of IL-33-mediated signaling. Proteomics. 2015;15:532-44 pubmed publisher |
Worboys J, Sinclair J, Yuan Y, Jørgensen C. Systematic evaluation of quantotypic peptides for targeted analysis of the human kinome. Nat Methods. 2014;11:1041-4 pubmed publisher |
