product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
SQSTM1/p62 (D5L7G) Mouse mAb
catalog :
88588
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
D5L7G
reactivity :
human
application :
western blot, immunocytochemistry, immunohistochemistry knockout validation, immunocytochemistry knockout validation
more info or order :
Cell Signaling Technology product webpage
citations: 9
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry knockout validation; human; loading ...; fig 1a
  • immunohistochemistry knockout validation; human; loading ...; fig 1b
Poon A, Saini H, Sethi S, O Sullivan G, Plun Favreau H, Wray S, et al. The role of SQSTM1 (p62) in mitochondrial function and clearance in human cortical neurons. Stem Cell Reports. 2021;16:1276-1289 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 7a, 7h
Li H, Zhao S, Shen L, Wang P, Liu S, Ma Y, et al. E2F2 inhibition induces autophagy via the PI3K/Akt/mTOR pathway in gastric cancer. Aging (Albany NY). 2021;13:13626-13643 pubmed publisher
  • immunocytochemistry; human; loading ...; fig a11s7b, a8s4b
  • western blot; human; loading ...; fig 3c
Wang X, Li X, Lin F, Sun H, Lin Y, Wang Z, et al. The lnc-CTSLP8 upregulates CTSL1 as a competitive endogenous RNA and promotes ovarian cancer metastasis. J Exp Clin Cancer Res. 2021;40:151 pubmed publisher
  • western blot; human; loading ...; fig 3c
Huang Z, Zhao J, Wang W, Zhou J, Zhang J. Depletion of LncRNA NEAT1 Rescues Mitochondrial Dysfunction Through NEDD4L-Dependent PINK1 Degradation in Animal Models of Alzheimer's Disease. Front Cell Neurosci. 2020;14:28 pubmed publisher
  • western blot; human; loading ...; fig 4e
Wang H, Bu L, Wang C, Zhang Y, Zhou H, Zhang X, et al. The Hsp70 inhibitor 2-phenylethynesulfonamide inhibits replication and carcinogenicity of Epstein-Barr virus by inhibiting the molecular chaperone function of Hsp70. Cell Death Dis. 2018;9:734 pubmed publisher
Tan T, Fu X, Qu J, Zhang M, Chen H, Wang Y, et al. 2,5-dimethyl celecoxib induces apoptosis and autophagy via activation of ROS/JNK axis in nasopharyngeal carcinoma cells. Aging (Albany NY). 2021;13:21483-21496 pubmed publisher
van Schie J, Faramarz A, Balk J, Stewart G, Cantelli E, Oostra A, et al. Warsaw Breakage Syndrome associated DDX11 helicase resolves G-quadruplex structures to support sister chromatid cohesion. Nat Commun. 2020;11:4287 pubmed publisher
Emami A, Shojaei S, da Silva Rosa S, Aghaei M, Samiei E, Vosoughi A, et al. Mechanisms of simvastatin myotoxicity: The role of autophagy flux inhibition. Eur J Pharmacol. 2019;862:172616 pubmed publisher
Moghadam A, da Silva Rosa S, Samiei E, Alizadeh J, Field J, Kawalec P, et al. Autophagy modulates temozolomide-induced cell death in alveolar Rhabdomyosarcoma cells. Cell Death Discov. 2018;4:52 pubmed publisher
product information
mab :
mab
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.