| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunohistochemistry - paraffin section; human; fig 8d
- western blot; human; loading ...; fig 3d, 8e
| Zhu H, Su Z, Ning J, Zhou L, Tan L, Sayed S, et al. Transmembrane protein 97 exhibits oncogenic properties via enhancing LRP6-mediated Wnt signaling in breast cancer. Cell Death Dis. 2021;12:912 pubmed publisher |
- western blot; mouse; 1:5000; loading ...; fig 9c
| Ma X, Takahashi Y, Wu W, Liang W, Chen J, Chakraborty D, et al. ADAM17 mediates ectodomain shedding of the soluble VLDL receptor fragment in the retinal epithelium. J Biol Chem. 2021;297:101185 pubmed publisher |
- western blot; human; loading ...; fig 3d
| Mygland L, Brinch S, Strand M, Olsen P, Aizenshtadt A, Lund K, et al. Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines. iScience. 2021;24:102807 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 6j
| Arnold F, Mahaddalkar P, Kraus J, Zhong X, Bergmann W, Srinivasan D, et al. Functional Genomic Screening During Somatic Cell Reprogramming Identifies DKK3 as a Roadblock of Organ Regeneration. Adv Sci (Weinh). 2021;8:2100626 pubmed publisher |
- immunocytochemistry; human; 1:200; loading ...; fig 3e
- western blot; human; 1:2000; loading ...; fig 1k, 2e
- immunohistochemistry - paraffin section; rat; 1:200; loading ...; fig 7c
| Shen J, Sun Y, Liu X, Zhu Y, Bao B, Gao T, et al. EGFL6 regulates angiogenesis and osteogenesis in distraction osteogenesis via Wnt/β-catenin signaling. Stem Cell Res Ther. 2021;12:415 pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig 7b
| Wang Y, Su Y, Yu G, Wang X, Chen X, Yu B, et al. Reduced Oligodendrocyte Precursor Cell Impairs Astrocytic Development in Early Life Stress. Adv Sci (Weinh). 2021;8:e2101181 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig s4d
| Zhao D, Zhong G, Li J, Pan J, Zhao Y, Song H, et al. Targeting E3 Ubiquitin-Ligase WWP1 Prevents Cardiac Hypertrophy Through Destabilizing DVL2 via Inhibition of K27-Linked Ubiquitination. Circulation. 2021;: pubmed publisher |
- western blot; mouse; loading ...; fig 1b, 6a
| Ianni A, Hofmann M, Kumari P, Tarighi S, Al tamari H, Görgens A, et al. Depletion of Numb and Numblike in Murine Lung Epithelial Cells Ameliorates Bleomycin-Induced Lung Fibrosis by Inhibiting the β-Catenin Signaling Pathway. Front Cell Dev Biol. 2021;9:639162 pubmed publisher |
- western blot; human; fig 7b
- western blot; mouse; loading ...; fig 4a
| Srivastava S, Zhou H, Setia O, Liu B, Kanasaki K, Koya D, et al. Loss of endothelial glucocorticoid receptor accelerates diabetic nephropathy. Nat Commun. 2021;12:2368 pubmed publisher |
- immunohistochemistry; mouse; 1:1600; loading ...; fig s8-2a
| Zewdu R, Mehrabad E, Ingram K, Fang P, Gillis K, Camolotto S, et al. An NKX2-1/ERK/WNT feedback loop modulates gastric identity and response to targeted therapy in lung adenocarcinoma. elife. 2021;10: pubmed publisher |
- western blot; mouse; loading ...; fig 1a
| Waaler J, Mygland L, Tveita A, Strand M, Solberg N, Olsen P, et al. Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models. Commun Biol. 2020;3:196 pubmed publisher |
- western blot; human; loading ...; fig 5i
| Rinastiti P, Ikeda K, Rahardini E, Miyagawa K, Tamada N, Kuribayashi Y, et al. Loss of family with sequence similarity 13, member A exacerbates pulmonary hypertension through accelerating endothelial-to-mesenchymal transition. PLoS ONE. 2020;15:e0226049 pubmed publisher |
- immunohistochemistry; human; loading ...; fig 6a
| Kluz P, Kolb R, Xie Q, Borcherding N, Liu Q, Luo Y, et al. Cancer cell-intrinsic function of CD177 in attenuating β-catenin signaling. Oncogene. 2020;39:2877-2889 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 9b
| Xing T, Benderman L, Sabu S, Parker J, Yang J, Lu Q, et al. Tight Junction Protein Claudin-7 Is Essential for Intestinal Epithelial Stem Cell Self-Renewal and Differentiation. Cell Mol Gastroenterol Hepatol. 2020;9:641-659 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 7e
- western blot; mouse; 1:1000; loading ...; fig s7d
| Quach C, Song Y, Guo H, Li S, Maazi H, Fung M, et al. A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice. Nat Commun. 2019;10:5681 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig s2a
| Eyre R, Alferez D, Santiago Gómez A, Spence K, McConnell J, Hart C, et al. Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling. Nat Commun. 2019;10:5016 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:800; loading ...; fig 3s2c
- western blot; human; 1:1000; loading ...; fig 8s1d
| Diaz Osterman C, Ozmadenci D, Kleinschmidt E, Taylor K, Barrie A, Jiang S, et al. FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy. elife. 2019;8: pubmed publisher |
- immunohistochemistry; mouse; fig 6b
- western blot; mouse; loading ...; fig 6a
| Huang K, Ru B, Zhang Y, Chan W, Chow S, Zhang J, et al. Sertoli cell-specific coxsackievirus and adenovirus receptor knockout regulates cell adhesion and gene transcription via β-catenin inactivation and Cdc42 activation. FASEB J. 2019;33:7588-7602 pubmed publisher |
- western blot; human; loading ...; fig 6b
| Wei X, Guo J, Li Q, Jia Q, Jing Q, Li Y, et al. Bach1 regulates self-renewal and impedes mesendodermal differentiation of human embryonic stem cells. Sci Adv. 2019;5:eaau7887 pubmed publisher |
- western blot; mouse; loading ...; fig 5e
| Hwang J, Kim A, Kim K, Il Park J, Oh H, Moon S, et al. TAZ couples Hippo/Wnt signalling and insulin sensitivity through Irs1 expression. Nat Commun. 2019;10:421 pubmed publisher |
- immunohistochemistry - frozen section; mouse; loading ...; fig 4g
| Koren E, Yosefzon Y, Ankawa R, Soteriou D, Jacob A, Nevelsky A, et al. ARTS mediates apoptosis and regeneration of the intestinal stem cell niche. Nat Commun. 2018;9:4582 pubmed publisher |
- immunocytochemistry; human; 1:1000; loading ...; fig 4d
| Mangolini M, Götte F, Moore A, Ammon T, Oelsner M, Lutzny Geier G, et al. Notch2 controls non-autonomous Wnt-signalling in chronic lymphocytic leukaemia. Nat Commun. 2018;9:3839 pubmed publisher |
- immunohistochemistry; human; 1:100; loading ...; fig s4c
- other; mouse; 1:500; loading ...; fig 8j
- western blot; mouse; 1:2000; loading ...; fig 8g
| Hsu J, Xia W, Hsu Y, Chan L, Yu W, Cha J, et al. STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion. Nat Commun. 2018;9:1908 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 4b
| Qin L, Ma K, Wang Z, Hu Z, Matas E, Wei J, et al. Social deficits in Shank3-deficient mouse models of autism are rescued by histone deacetylase (HDAC) inhibition. Nat Neurosci. 2018;21:564-575 pubmed publisher |
- western blot; mouse; loading ...; fig 1e
| Macdougall C, Wood E, Loschko J, Scagliotti V, Cassidy F, Robinson M, et al. Visceral Adipose Tissue Immune Homeostasis Is Regulated by the Crosstalk between Adipocytes and Dendritic Cell Subsets. Cell Metab. 2018;27:588-601.e4 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 1a
| Frey J, Kim S, Li Z, Wolfgang M, Riddle R. β-Catenin Directs Long-Chain Fatty Acid Catabolism in the Osteoblasts of Male Mice. Endocrinology. 2018;159:272-284 pubmed publisher |
- western blot; mouse; loading ...; fig 3g
| Matsumoto Y, La Rose J, Lim M, Adissu H, Law N, Mao X, et al. Ubiquitin ligase RNF146 coordinates bone dynamics and energy metabolism. J Clin Invest. 2017;127:2612-2625 pubmed publisher |
- immunocytochemistry; mouse; loading ...; fig 5b
- western blot; mouse; loading ...; fig 5c
| Dogan A, Demirci S, Apdik H, Bayrak O, Gulluoglu S, Tuysuz E, et al. A new hope for obesity management: Boron inhibits adipogenesis in progenitor cells through the Wnt/β-catenin pathway. Metabolism. 2017;69:130-142 pubmed publisher |
- western blot; human; loading ...; fig 4a
| Domingues M, Martinez Sanz J, Papon L, Larue L, Mouawad L, Bonaventure J. Structure-based mutational analysis of ICAT residues mediating negative regulation of ?-catenin co-transcriptional activity. PLoS ONE. 2017;12:e0172603 pubmed publisher |
- western blot; mouse; loading ...; fig 5c
| Le Dour C, Macquart C, Sera F, Homma S, Bonne G, Morrow J, et al. Decreased WNT/?-catenin signalling contributes to the pathogenesis of dilated cardiomyopathy caused by mutations in the lamin a/C gene. Hum Mol Genet. 2017;26:333-343 pubmed publisher |
- immunocytochemistry; mouse; 1:100; loading ...; fig s5h
| Beyer S, Pontis J, Schirwis E, Battisti V, Rudolf A, Le Grand F, et al. Canonical Wnt signalling regulates nuclear export of Setdb1 during skeletal muscle terminal differentiation. Cell Discov. 2016;2:16037 pubmed |
- western blot; human; 1:5000; loading ...; fig 1b
| Gammons M, Rutherford T, Steinhart Z, Angers S, Bienz M. Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay. J Cell Sci. 2016;129:3892-3902 pubmed |
- western blot; human; loading ...; fig 6a
| Kong X, Liu F, Gao J. MiR-155 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells through the activation of PI3K/SGK3/β-catenin signaling pathways. Oncotarget. 2016;7:66051-66060 pubmed publisher |
- immunocytochemistry; mouse; loading ...; fig 6c
| Hofbauer P, Jung J, McArdle T, Ogle B. Simple Monolayer Differentiation of Murine Cardiomyocytes via Nutrient Deprivation-Mediated Activation of β-Catenin. Stem Cell Rev. 2016;12:731-743 pubmed |
- western blot; human; 1:4000; fig 6
| Jiang S, Chen G, Feng L, Jiang Z, Yu M, Bao J, et al. Disruption of kif3a results in defective osteoblastic differentiation in dental mesenchymal stem/precursor cells via the Wnt signaling pathway. Mol Med Rep. 2016;14:1891-900 pubmed publisher |
- western blot; mouse; fig 2
| Fagnocchi L, Cherubini A, Hatsuda H, Fasciani A, Mazzoleni S, Poli V, et al. A Myc-driven self-reinforcing regulatory network maintains mouse embryonic stem cell identity. Nat Commun. 2016;7:11903 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 4e
| Jacobsen A, Heijmans N, Verkaar F, Smit M, Heringa J, van Amerongen R, et al. Construction and Experimental Validation of a Petri Net Model of Wnt/β-Catenin Signaling. PLoS ONE. 2016;11:e0155743 pubmed publisher |
- immunohistochemistry - paraffin section; human; 0.5 ug/ml; fig st1
- western blot; human; fig 2
| Kaur A, Webster M, Marchbank K, Behera R, Ndoye A, Kugel C, et al. sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance. Nature. 2016;532:250-4 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:400; fig s7
- immunocytochemistry; mouse; 1:800; fig s7
| Beyaz S, Mana M, Roper J, Kedrin D, Saadatpour A, Hong S, et al. High-fat diet enhances stemness and tumorigenicity of intestinal progenitors. Nature. 2016;531:53-8 pubmed publisher |
- western blot; human; loading ...; fig 5a
| Cui H, Wang S, Miao J, Fu Z, Feng F, Wu J, et al. CD147 regulates cancer migration via direct interaction with Annexin A2 and DOCK3-β-catenin-WAVE2 signaling. Oncotarget. 2016;7:5613-29 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:250; loading ...; fig 6d
| Goodnough L, Dinuoscio G, ATIT R. Twist1 contributes to cranial bone initiation and dermal condensation by maintaining Wnt signaling responsiveness. Dev Dyn. 2016;245:144-56 pubmed publisher |
- western blot; mouse; 1:500; fig 2a
| Abshagen K, Senne M, Genz B, Thomas M, Vollmar B. Differential Effects of Axin2 Deficiency on the Fibrogenic and Regenerative Response in Livers of Bile Duct-Ligated Mice. Eur Surg Res. 2015;55:328-340 pubmed |
- western blot; human; 1:1000; fig 3c
| Ma S, Yang L, Niu T, Cheng C, Zhong L, Zheng M, et al. SKLB-677, an FLT3 and Wnt/β-catenin signaling inhibitor, displays potent activity in models of FLT3-driven AML. Sci Rep. 2015;5:15646 pubmed publisher |
- western blot; human; 1:1000; fig 3a
| MartÃnez Revollar G, Garay E, Martín Tapia D, Nava P, Huerta M, Lopez Bayghen E, et al. Heterogeneity between triple negative breast cancer cells due to differential activation of Wnt and PI3K/AKT pathways. Exp Cell Res. 2015;339:67-80 pubmed publisher |
- immunocytochemistry; human
- immunohistochemistry; human
- western blot; human; fig 4
| Xiong W, Zhang L, Yu L, Xie W, Man Y, Xiong Y, et al. Estradiol promotes cells invasion by activating β-catenin signaling pathway in endometriosis. Reproduction. 2015;150:507-16 pubmed publisher |
- immunocytochemistry; human; fig 3C
| Mathur R, Sehgal L, Braun F, Berkova Z, Romaguerra J, Wang M, et al. Targeting Wnt pathway in mantle cell lymphoma-initiating cells. J Hematol Oncol. 2015;8:63 pubmed publisher |
- western blot; mouse; 1:1000; fig 2e
| Dow L, Fisher J, O Rourke K, Muley A, Kastenhuber E, Livshits G, et al. Inducible in vivo genome editing with CRISPR-Cas9. Nat Biotechnol. 2015;33:390-394 pubmed publisher |
- blocking or activating experiments; human; loading ...; fig 5b
| Traenkle B, Emele F, Anton R, Poetz O, Haeussler R, Maier J, et al. Monitoring interactions and dynamics of endogenous beta-catenin with intracellular nanobodies in living cells. Mol Cell Proteomics. 2015;14:707-23 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; fig 4
- western blot; mouse; fig 4
| Matsuyama M, Nomori A, Nakakuni K, Shimono A, Fukushima M. Secreted Frizzled-related protein 1 (Sfrp1) regulates the progression of renal fibrosis in a mouse model of obstructive nephropathy. J Biol Chem. 2014;289:31526-33 pubmed publisher |
- immunohistochemistry - paraffin section; mouse
| Valkenburg K, Yu X, De Marzo A, Spiering T, Matusik R, Williams B. Activation of Wnt/β-catenin signaling in a subpopulation of murine prostate luminal epithelial cells induces high grade prostate intraepithelial neoplasia. Prostate. 2014;74:1506-20 pubmed publisher |
| Aripaka K, Gudey S, Zang G, Schmidt A, Åhrling S, Österman L, et al. TRAF6 function as a novel co-regulator of Wnt3a target genes in prostate cancer. EBioMedicine. 2019;: pubmed publisher |
| MacDougall M, Clarke R, Merrill B. Intracellular Ca2+ Homeostasis and Nuclear Export Mediate Exit from Naive Pluripotency. Cell Stem Cell. 2019;: pubmed publisher |
| Lun X, Szklarczyk D, Gábor A, Dobberstein N, Zanotelli V, Saez Rodriguez J, et al. Analysis of the Human Kinome and Phosphatome by Mass Cytometry Reveals Overexpression-Induced Effects on Cancer-Related Signaling. Mol Cell. 2019;74:1086-1102.e5 pubmed publisher |
| Knight M, Karuppaiah K, Lowe M, Mohanty S, Zondervan R, Bell S, et al. R-spondin-2 is a Wnt agonist that regulates osteoblast activity and bone mass. Bone Res. 2018;6:24 pubmed publisher |
| Latifi Z, Fattahi A, Hamdi K, Ghasemzadeh A, Karimi P, Nejabati H, et al. Wnt Signaling Pathway in Uterus of Normal and Seminal Vesicle Excised Mated Mice during Pre-implantation Window. Geburtshilfe Frauenheilkd. 2018;78:412-422 pubmed publisher |
| Hadjadj D, Kim S, Denecker T, Ben Driss L, Cadoret J, Maric C, et al. A hypothesis-driven approach identifies CDK4 and CDK6 inhibitors as candidate drugs for treatments of adrenocortical carcinomas. Aging (Albany NY). 2017;9:2695-2716 pubmed publisher |
| Wang H, Ren Y, Hu X, Ma M, Wang X, Liang H, et al. Effect of Wnt Signaling on the Differentiation of Islet ?-Cells from Adipose-Derived Stem Cells. Biomed Res Int. 2017;2017:2501578 pubmed publisher |
| Ragni C, Diguet N, Le Garrec J, Novotova M, Resende T, Pop S, et al. Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth. Nat Commun. 2017;8:14582 pubmed publisher |
| Softic S, Boucher J, Solheim M, Fujisaka S, Haering M, Homan E, et al. Lipodystrophy Due to Adipose Tissue-Specific Insulin Receptor Knockout Results in Progressive NAFLD. Diabetes. 2016;65:2187-200 pubmed publisher |
| Kaushal G, Rognoni E, Lichtenberger B, Driskell R, Kretzschmar K, Hoste E, et al. Fate of Prominin-1 Expressing Dermal Papilla Cells during Homeostasis, Wound Healing and Wnt Activation. J Invest Dermatol. 2015;135:2926-2934 pubmed publisher |
| Arthur S, Zwetsloot K, Lawrence M, Nieman D, Lila M, Grace M, et al. Ajuga turkestanica increases Notch and Wnt signaling in aged skeletal muscle. Eur Rev Med Pharmacol Sci. 2014;18:2584-92 pubmed |
| Gauger K, Bassa L, Henchey E, Wyman J, Ser Dolansky J, Shimono A, et al. The effects of diet induced obesity on breast cancer associated pathways in mice deficient in SFRP1. Mol Cancer. 2014;13:117 pubmed publisher |
