product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Cleaved Caspase-3 (Asp175) (D3E9) Rabbit mAb (Pacific Blue™ Conjugate)
catalog :
8788
clonality :
monoclonal
host :
rabbit
conjugate :
Pacific Blue
clone name :
D3E9
reactivity :
human, mouse, rat, cow
application :
flow cytometry
more info or order :
Cell Signaling Technology product webpage
citations: 6
Reference
Vercoulen Y, Kondo Y, Iwig J, Janssen A, White K, Amini M, et al. A Histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1. elife. 2017;6: pubmed publisher
Cheung J, Dickinson D, Moss J, Schuler M, Spellman R, Heard P. Histone markers identify the mode of action for compounds positive in the TK6 micronucleus assay. Mutat Res Genet Toxicol Environ Mutagen. 2015;777:7-16 pubmed publisher
Abdi J, Garssen J, Faber J, Redegeld F. Omega-3 fatty acids, EPA and DHA induce apoptosis and enhance drug sensitivity in multiple myeloma cells but not in normal peripheral mononuclear cells. J Nutr Biochem. 2014;25:1254-62 pubmed publisher
Abdi J, Mutis T, Garssen J, Redegeld F. Toll-like receptor (TLR)-1/2 triggering of multiple myeloma cells modulates their adhesion to bone marrow stromal cells and enhances bortezomib-induced apoptosis. PLoS ONE. 2014;9:e96608 pubmed publisher
Bryce S, Bemis J, Mereness J, Spellman R, Moss J, Dickinson D, et al. Interpreting in vitro micronucleus positive results: simple biomarker matrix discriminates clastogens, aneugens, and misleading positive agents. Environ Mol Mutagen. 2014;55:542-55 pubmed publisher
Migliardi G, Sassi F, Torti D, Galimi F, Zanella E, Buscarino M, et al. Inhibition of MEK and PI3K/mTOR suppresses tumor growth but does not cause tumor regression in patient-derived xenografts of RAS-mutant colorectal carcinomas. Clin Cancer Res. 2012;18:2515-25 pubmed publisher
product information
SKU :
8788S
Product-Name :
Cleaved Caspase-3 (Asp175) (D3E9) Rabbit mAb (Pacific Blue™ Conjugate)
Size :
100 ul
Price-(USD) :
291 USD
Species-x-Reactivity :
H, (M, R, Mk, B, Pg)
Applications :
Flow cytometry
Product-Category :
Apoptosis
Shipping-Temp :
COLD
Storage-Temp :
4°C
Product-Type :
Monoclonal Antibody
Host :
Rabbit
Target :
Casp3 (Asp175) cleaved
Primary-Protein :
Casp3
Alt-Names :
Apopain,CASP-3,CASP3,CPP-32,CPP32,CPP32B,Caspase-3,Caspase-3 subunit p12,Caspase-3 subunit p17,Cysteine protease CPP32,PARP cleavage protease,Protein Yama,SCA-1,SREBP cleavage activity 1,Yama,caspase 3, apoptosis-related cysteine peptidase,caspase 3, apoptosis-related cysteine protease,procaspase3
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.