product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
SUV39H1 (D11B6) Rabbit mAb
catalog :
8729
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D11B6
reactivity :
human, mouse, rat, bovine
application :
western blot, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, western blot knockout validation
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; 1:1000; fig s1
Walter M, Teissandier A, Pérez Palacios R, Bourc his D. An epigenetic switch ensures transposon repression upon dynamic loss of DNA methylation in embryonic stem cells. elife. 2016;5: pubmed publisher
  • immunocytochemistry; rat; 1:200; loading ...; fig 3e
  • chromatin immunoprecipitation; mouse; loading ...; fig 6d
  • western blot; mouse; loading ...; fig 6c
Qi L, Chi X, Zhang X, Feng X, Chu W, Zhang S, et al. Kindlin-2 suppresses transcription factor GATA4 through interaction with SUV39H1 to attenuate hypertrophy. Cell Death Dis. 2019;10:890 pubmed publisher
  • chromatin immunoprecipitation; human; loading ...; fig s3
Nguyen K, Das B, Dobrowolski C, Karn J. Multiple Histone Lysine Methyltransferases Are Required for the Establishment and Maintenance of HIV-1 Latency. MBio. 2017;8: pubmed publisher
  • immunocytochemistry; mouse; 1:1000; fig 5,6
Hatanaka Y, Inoue K, Oikawa M, Kamimura S, Ogonuki N, Kodama E, et al. Histone chaperone CAF-1 mediates repressive histone modifications to protect preimplantation mouse embryos from endogenous retrotransposons. Proc Natl Acad Sci U S A. 2015;112:14641-6 pubmed publisher
  • western blot; rat; 1:1000; fig 2
Liu J, Magri L, Zhang F, Marsh N, Albrecht S, Huynh J, et al. Chromatin landscape defined by repressive histone methylation during oligodendrocyte differentiation. J Neurosci. 2015;35:352-65 pubmed publisher
  • immunocytochemistry; mouse
Hattangadi S, Martinez Morilla S, Patterson H, Shi J, Burke K, Avila Figueroa A, et al. Histones to the cytosol: exportin 7 is essential for normal terminal erythroid nuclear maturation. Blood. 2014;124:1931-40 pubmed
Tsusaka T, Kikuchi M, Shimazu T, Suzuki T, Sohtome Y, Akakabe M, et al. Tri-methylation of ATF7IP by G9a/GLP recruits the chromodomain protein MPP8. Epigenetics Chromatin. 2018;11:56 pubmed publisher
Jung H, Byun H, Jee B, Min S, Jeoun U, Lee Y, et al. The Ubiquitin-like with PHD and Ring Finger Domains 1 (UHRF1)/DNA Methyltransferase 1 (DNMT1) Axis Is a Primary Regulator of Cell Senescence. J Biol Chem. 2017;292:3729-3739 pubmed publisher
Chatterjee B, Wolff D, Jothi M, Mal M, Mal A. p38? MAPK disables KMT1A-mediated repression of myogenic differentiation program. Skelet Muscle. 2016;6:28 pubmed publisher
Maison C, Bailly D, Quivy J, Almouzni G. The methyltransferase Suv39h1 links the SUMO pathway to HP1? marking at pericentric heterochromatin. Nat Commun. 2016;7:12224 pubmed publisher
Chen C, Koche R, Sinha A, Deshpande A, Zhu N, Eng R, et al. DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia. Nat Med. 2015;21:335-43 pubmed publisher
Sone K, Piao L, Nakakido M, Ueda K, Jenuwein T, Nakamura Y, et al. Critical role of lysine 134 methylation on histone H2AX for γ-H2AX production and DNA repair. Nat Commun. 2014;5:5691 pubmed publisher
Tan Y, Tajik A, Chen J, Jia Q, Chowdhury F, Wang L, et al. Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expression. Nat Commun. 2014;5:4619 pubmed publisher
product information
SKU :
8729S
Product-Name :
SUV39H1 (D11B6) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk, (B)
Applications :
Immunoprecipitation
Product-Category :
Chromatin Regulation / Nuclear Function
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
48
Host :
Rabbit
Target :
SUV39H1
Primary-Protein :
SUV39H1
Alt-Names :
H3-K9-HMTase 1,Histone H3-K9 methyltransferase 1,Histone-lysine N-methyltransferase SUV39H1,KMT1A,Lysine N-methyltransferase 1A,MG44,Position-effect variegation 3-9 homolog,SUV39H,SUV39H1,SUV91,Su(var)3-9 homolog 1,Suppressor of variegation 3-9 homolog 1,histone-lysine N-methyltransferase, H3 lysine-9 specific 1,suppressor of variegation 3-9 homolog 1 (Drosophila)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.