MEK1/2 (D1A5) Rabbit mAb | Cell Signaling Technology 8727 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

MEK1/2 (D1A5) Rabbit mAb

catalog :

8727

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

D1A5

reactivity :

human, mouse

application :

western blot, immunocytochemistry, flow cytometry

more info or order :

Cell Signaling Technology product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:1000; loading ...; fig 8a	Stavoe A, Gopal P, Gubas A, Tooze S, Holzbaur E. Expression of WIPI2B counteracts age-related decline in autophagosome biogenesis in neurons. elife. 2019;8: pubmed publisher
western blot; human; loading ...; fig 4a	Qiang L, Wang J, Zhang Y, Ge P, Chai Q, Li B, et al. Mycobacterium tuberculosis Mce2E suppresses the macrophage innate immune response and promotes epithelial cell proliferation. Cell Mol Immunol. 2018;: pubmed publisher
western blot; human; 1:1000; loading ...; fig 1e	Vlachogiannis G, Hedayat S, Vatsiou A, Jamin Y, Fernández Mateos J, Khan K, et al. Patient-derived organoids model treatment response of metastatic gastrointestinal cancers. Science. 2018;359:920-926 pubmed publisher
western blot; mouse; fig 5a	Ambrogio C, Köhler J, Zhou Z, Wang H, Paranal R, Li J, et al. KRAS Dimerization Impacts MEK Inhibitor Sensitivity and Oncogenic Activity of Mutant KRAS. Cell. 2018;172:857-868.e15 pubmed publisher
western blot; mouse; loading ...; fig s3b	Kunimoto H, Meydan C, Nazir A, Whitfield J, Shank K, Rapaport F, et al. Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity. Cancer Cell. 2018;33:44-59.e8 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 7b	Bai X, Hong W, Cai P, Chen Y, Xu C, Cao D, et al. Valproate induced hepatic steatosis by enhanced fatty acid uptake and triglyceride synthesis. Toxicol Appl Pharmacol. 2017;324:12-25 pubmed publisher
western blot; human; 1:1000; loading ...; fig 5f	Zimmermann M, Arachchige Don A, Donaldson M, Patriarchi T, Horne M. Cyclin G2 promotes cell cycle arrest in breast cancer cells responding to fulvestrant and metformin and correlates with patient survival. Cell Cycle. 2016;15:3278-3295 pubmed
western blot; human; fig 2	Kuramoto K, Wang N, Fan Y, Zhang W, Schoenen F, Frankowski K, et al. Autophagy activation by novel inducers prevents BECN2-mediated drug tolerance to cannabinoids. Autophagy. 2016;12:1460-71 pubmed publisher
western blot; mouse; fig 4	Yang C, Lowther K, Lalioti M, Seli E. Embryonic Poly(A)-Binding Protein (EPAB) Is Required for Granulosa Cell EGF Signaling and Cumulus Expansion in Female Mice. Endocrinology. 2016;157:405-16 pubmed publisher
western blot; human; fig 4	McCormack R, de Armas L, Shiratsuchi M, Fiorentino D, Olsson M, Lichtenheld M, et al. Perforin-2 is essential for intracellular defense of parenchymal cells and phagocytes against pathogenic bacteria. elife. 2015;4: pubmed publisher
western blot; human; loading ...; fig 2g	Yoda A, Adelmant G, Tamburini J, Chapuy B, Shindoh N, Yoda Y, et al. Mutations in G protein Î² subunits promote transformation and kinase inhibitor resistance. Nat Med. 2015;21:71-5 pubmed publisher
western blot; human	Hast B, Cloer E, Goldfarb D, Li H, Siesser P, Yan F, et al. Cancer-derived mutations in KEAP1 impair NRF2 degradation but not ubiquitination. Cancer Res. 2014;74:808-17 pubmed publisher
	Dasgupta M, Unal H, Willard B, Yang J, Karnik S, Stark G. Critical role for lysine 685 in gene expression mediated by transcription factor unphosphorylated STAT3. J Biol Chem. 2014;289:30763-71 pubmed publisher
	Cao Y, Xia D, Qi S, Du J, Ma P, Wang S, et al. Epiregulin can promote proliferation of stem cells from the dental apical papilla via MEK/Erk and JNK signalling pathways. Cell Prolif. 2013;46:447-56 pubmed publisher
	Nakdimon I, Walser M, Fröhli E, Hajnal A. PTEN negatively regulates MAPK signaling during Caenorhabditis elegans vulval development. PLoS Genet. 2012;8:e1002881 pubmed publisher

product information

SKU :

8727S

Product-Name :

MEK1/2 (D1A5) Rabbit mAb

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

H, M, R, Mk, (Hm), Dm, (X, Z, B, Dg, Pg, Ce)

Applications :

Flow cytometry

Product-Category :

MAP Kinase Signaling

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

Host :

Rabbit

Target :

MEK1/MEK2

more info or order :

Cell Signaling Technology product webpage