product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
p38 MAPK (D13E1) XP® Rabbit mAb
catalog :
8690
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D13E1
reactivity :
human, mouse, rat, pigs
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
Cell Signaling Technology product webpage
citations: 170
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 6g
Hua X, Ge S, Zhang M, Mo F, Zhang L, Zhang J, et al. Pathogenic Roles of CXCL10 in Experimental Autoimmune Prostatitis by Modulating Macrophage Chemotaxis and Cytokine Secretion. Front Immunol. 2021;12:706027 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4c
Correia de Sousa M, Calo N, Sobolewski C, Gjorgjieva M, Clement S, Maeder C, et al. Mir-21 Suppression Promotes Mouse Hepatocarcinogenesis. Cancers (Basel). 2021;13: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4e
Hu Y, Li C, Wang X, Chen W, Qian Y, Dai X. TREM2, Driving the Microglial Polarization, Has a TLR4 Sensitivity Profile After Subarachnoid Hemorrhage. Front Cell Dev Biol. 2021;9:693342 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 7d
Zuo Y, Xie J, Li X, Li Y, Thirupathi A, Zhang J, et al. Ferritinophagy-Mediated Ferroptosis Involved in Paraquat-Induced Neurotoxicity of Dopaminergic Neurons: Implication for Neurotoxicity in PD. Oxid Med Cell Longev. 2021;2021:9961628 pubmed publisher
  • western blot; human; loading ...; fig s2
Chen X, Miao M, Zhou M, Chen J, Li D, Zhang L, et al. Poly-L-arginine promotes asthma angiogenesis through induction of FGFBP1 in airway epithelial cells via activation of the mTORC1-STAT3 pathway. Cell Death Dis. 2021;12:761 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 5f
  • western blot; human; 1:1000; loading ...; fig 3f, 5d
Fan M, Zhang G, Chen W, Qi L, Xie M, Zhang Y, et al. Siglec-15 Promotes Tumor Progression in Osteosarcoma via DUSP1/MAPK Pathway. Front Oncol. 2021;11:710689 pubmed publisher
  • western blot; rat; 1:1000; fig 3i
Lin H, Guan L, Meng L, Uzui H, Guo H. SGLT1 Knockdown Attenuates Cardiac Fibroblast Activation in Diabetic Cardiac Fibrosis. Front Pharmacol. 2021;12:700366 pubmed publisher
  • western blot; human; 1:1000; fig 3e
Kulkarni N, O Neill A, Dokoshi T, Luo E, Wong G, Gallo R. Sequence determinants in the cathelicidin LL-37 that promote inflammation via presentation of RNA to scavenger receptors. J Biol Chem. 2021;297:100828 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 1a
Xu L, Humphries F, Delagic N, Wang B, Holland A, Edgar K, et al. ECSIT is a critical limiting factor for cardiac function. JCI Insight. 2021;6: pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 7a
Huang W, Liu H, Pan Y, Yang H, Lin J, Zhang H. Mechanical stretching of the pulmonary vein mediates pulmonary hypertension due to left heart disease by regulating SAC/MAPK pathway and the expression of IL-6 and TNF-α. J Cardiothorac Surg. 2021;16:127 pubmed publisher
  • western blot; mouse; loading ...; fig 6a
Zheng H, Zhang Y, He J, Yang Z, Zhang R, Li L, et al. Hydroxychloroquine Inhibits Macrophage Activation and Attenuates Renal Fibrosis After Ischemia-Reperfusion Injury. Front Immunol. 2021;12:645100 pubmed publisher
  • western blot; mouse; 1:1000; fig 6b
Shen K, Li R, Zhang X, Qu G, Li R, Wang Y, et al. Acetyl oxygen benzoate engeletin ester promotes KLF4 degradation leading to the attenuation of pulmonary fibrosis via inhibiting TGFβ1-smad/p38MAPK-lnc865/lnc556-miR-29b-2-5p-STAT3 signal pathway. Aging (Albany NY). 2021;13:13807-13821 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 1f
Chang N, Yeh C, Lin Y, Kuo K, Fong I, Kounis N, et al. Garcinol Attenuates Lipoprotein(a)-Induced Oxidative Stress and Inflammatory Cytokine Production in Ventricular Cardiomyocyte through α7-Nicotinic Acetylcholine Receptor-Mediated Inhibition of the p38 MAPK and NF-κB Signaling Pathways. Antioxidants (Basel). 2021;10: pubmed publisher
  • western blot; mouse; loading ...; fig s3
Zhang X, Gou Y, Zhang Y, Li J, Han K, Xu Y, et al. Hepcidin overexpression in astrocytes alters brain iron metabolism and protects against amyloid-β induced brain damage in mice. Cell Death Discov. 2020;6:113 pubmed publisher
  • western blot; rat; loading ...; fig 6b
Chen Y, Li J, Ma B, Li N, Wang S, Sun Z, et al. MSC-derived exosomes promote recovery from traumatic brain injury via microglia/macrophages in rat. Aging (Albany NY). 2020;12:18274-18296 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 6a, 6b
Hu J, Wang H, Li X, Liu Y, Mi Y, Kong H, et al. Fibrinogen-like protein 2 aggravates nonalcoholic steatohepatitis via interaction with TLR4, eliciting inflammation in macrophages and inducing hepatic lipid metabolism disorder. Theranostics. 2020;10:9702-9720 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 3c
Sun Z, Ji N, Ma Q, Zhu R, Chen Z, Wang Z, et al. Epithelial-Mesenchymal Transition in Asthma Airway Remodeling Is Regulated by the IL-33/CD146 Axis. Front Immunol. 2020;11:1598 pubmed publisher
  • western blot; mouse; loading ...; fig 7a
Chakrabarti M, Al Sammarraie N, Gebere M, Bhattacharya A, Chopra S, Johnson J, et al. Transforming Growth Factor Beta3 is Required for Cardiovascular Development. J Cardiovasc Dev Dis. 2020;7: pubmed publisher
  • western blot; mouse; loading ...; fig 4c
Du T, Yan Z, Zhu S, Chen G, Wang L, Ye Z, et al. QKI deficiency leads to osteoporosis by promoting RANKL-induced osteoclastogenesis and disrupting bone metabolism. Cell Death Dis. 2020;11:330 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 8f
Kong Y, Xu S. Juglanin administration protects skin against UVB‑induced injury by reducing Nrf2‑dependent ROS generation. Int J Mol Med. 2020;46:67-82 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 5a
Yan S, Ding H, Peng J, Wang X, Pang C, Wei J, et al. Down-regulation of protease-activated receptor 2 ameliorated osteoarthritis in rats through regulation of MAPK/NF-κB signaling pathway in vivo and in vitro. Biosci Rep. 2020;40: pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig s2a
Chen F, Jiang G, Liu H, Li Z, Pei Y, Wang H, et al. Melatonin alleviates intervertebral disc degeneration by disrupting the IL-1β/NF-κB-NLRP3 inflammasome positive feedback loop. Bone Res. 2020;8:10 pubmed publisher
  • western blot; mouse; loading ...; fig 4b
Xiang S, Chen K, Xu L, Wang T, Guo C. Bergenin Exerts Hepatoprotective Effects by Inhibiting the Release of Inflammatory Factors, Apoptosis and Autophagy via the PPAR-γ Pathway. Drug Des Devel Ther. 2020;14:129-143 pubmed publisher
  • western blot; human; loading ...; fig 4a
Lin L, Li Y, Liu M, Li Q, Liu Q, Li R. The Interleukin-33/ST2 axis promotes glioma mesenchymal transition, stemness and TMZ resistance via JNK activation. Aging (Albany NY). 2020;12:1685-1703 pubmed publisher
  • western blot; human; 1:400; loading ...; fig 4a
Hong Z, Wang Z, Zhou B, Wang J, Tong H, Liao Y, et al. Effects of evodiamine on PI3K/Akt and MAPK/ERK signaling pathways in pancreatic cancer cells. Int J Oncol. 2020;56:783-793 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4a
Zhou Z, Zhou Q, Wu X, Xu S, Hu X, Tao X, et al. VCAM-1 secreted from cancer-associated fibroblasts enhances the growth and invasion of lung cancer cells through AKT and MAPK signaling. Cancer Lett. 2020;473:62-73 pubmed publisher
  • western blot; rat; loading ...; fig 6a
Huang X, Ni B, Xi Y, Chu X, Zhang R, You H. Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis. Aging (Albany NY). 2019;11:12532-12545 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4d
Yuan M, Xie F, Xia X, Zhong K, Lian L, Zhang S, et al. UNC5C‑knockdown enhances the growth and metastasis of breast cancer cells by potentiating the integrin α6/β4 signaling pathway. Int J Oncol. 2019;: pubmed publisher
  • western blot; mouse; loading ...; fig s4i
Yu H, Rimbert A, Palmer A, Toyohara T, Xia Y, Xia F, et al. GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis. Cell. 2019;179:1276-1288.e14 pubmed publisher
  • western blot; mouse; loading ...; fig s13h
Moya I, Castaldo S, Van den Mooter L, Soheily S, Sansores Garcia L, Jacobs J, et al. Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice. Science. 2019;366:1029-1034 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 3g, s1w
Lu Y, Zheng Y, Coyaud E, Zhang C, Selvabaskaran A, Yu Y, et al. Palmitoylation of NOD1 and NOD2 is required for bacterial sensing. Science. 2019;366:460-467 pubmed publisher
  • western blot; mouse; loading ...; fig 6b
  • western blot; human; loading ...; fig 6a
Lai T, Wen X, Wu D, Su G, Gao Y, Chen C, et al. SIRT1 protects against urban particulate matter-induced airway inflammation. Int J Chron Obstruct Pulmon Dis. 2019;14:1741-1752 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 11a
Xu B, Lang L, Li S, Guo J, Wang J, Yang H, et al. Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure. Biomolecules. 2019;9: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5a
Zhao J, Peng W, Ran Y, Ge H, Zhang C, Zou H, et al. Dysregulated expression of ACTN4 contributes to endothelial cell injury via the activation of the p38-MAPK/p53 apoptosis pathway in preeclampsia. J Physiol Biochem. 2019;: pubmed publisher
  • western blot; human; fig 7f
Jiang C, Trudeau S, Cheong T, Guo R, Teng M, Wang L, et al. CRISPR/Cas9 Screens Reveal Multiple Layers of B cell CD40 Regulation. Cell Rep. 2019;28:1307-1322.e8 pubmed publisher
  • western blot; human; 1:1000; fig s2g
Bi J, Ichu T, Zanca C, Yang H, Zhang W, Gu Y, et al. Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling. Cell Metab. 2019;30:525-538.e8 pubmed publisher
  • western blot; human; loading ...; fig 4d
Du F, Qiao C, Li X, Chen Z, Liu H, Wu S, et al. Forkhead box K2 promotes human colorectal cancer metastasis by upregulating ZEB1 and EGFR. Theranostics. 2019;9:3879-3902 pubmed publisher
  • western blot; human; 1:5000; loading ...; fig 2h
Hari P, Millar F, Tarrats N, Birch J, Quintanilla A, Rink C, et al. The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype. Sci Adv. 2019;5:eaaw0254 pubmed publisher
  • western blot; human; 1:500; fig s10d
Genet G, Boyé K, Mathivet T, Ola R, Zhang F, Dubrac A, et al. Endophilin-A2 dependent VEGFR2 endocytosis promotes sprouting angiogenesis. Nat Commun. 2019;10:2350 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 7c
Liu X, Zhou Z, Li W, Zhang S, Li J, Zhou M, et al. Heparanase Promotes Tumor Growth and Liver Metastasis of Colorectal Cancer Cells by Activating the p38/MMP1 Axis. Front Oncol. 2019;9:216 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4g
Udden S, Kwak Y, Godfrey V, Khan M, Khan S, Loof N, et al. NLRP12 suppresses hepatocellular carcinoma via downregulation of cJun N-terminal kinase activation in the hepatocyte. elife. 2019;8: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 6d
Chang H, Di T, Wang Y, Zeng X, Li G, Wan Q, et al. Seipin deletion in mice enhances phosphorylation and aggregation of tau protein through reduced neuronal PPARγ and insulin resistance. Neurobiol Dis. 2019;127:350-361 pubmed publisher
  • western blot; human; loading ...; fig s6b
Kennedy S, Han J, Portman N, Nobis M, Hastings J, Murphy K, et al. Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer. Breast Cancer Res. 2019;21:43 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:3000; loading ...; fig s4c, s4h
Mammone T, Chidlow G, Casson R, Wood J. Improved immunohistochemical detection of phosphorylated mitogen-activated protein kinases in the injured rat optic nerve head. Histochem Cell Biol. 2019;151:435-456 pubmed publisher
  • western blot; rat; loading ...; fig s1
Hlavac N, VandeVord P. Astrocyte Mechano-Activation by High-Rate Overpressure Involves Alterations in Structural and Junctional Proteins. Front Neurol. 2019;10:99 pubmed publisher
  • western blot; human; loading ...; fig 6f
  • western blot; mouse; loading ...; fig 6a
Mentrup T, Theodorou K, Cabrera Cabrera F, Helbig A, Happ K, Gijbels M, et al. Atherogenic LOX-1 signaling is controlled by SPPL2-mediated intramembrane proteolysis. J Exp Med. 2019;: pubmed publisher
  • western blot; mouse; 1:2000; loading ...; fig 8b
  • western blot; human; 1:2000; loading ...; fig 8a
Zhang S, Liu W, Yang Y, Sun K, Li S, Xu H, et al. Tmem30a Deficiency in endothelial cells impairs cell proliferation and angiogenesis. J Cell Sci. 2019;: pubmed publisher
  • western blot; mouse; 1:3000; loading ...; fig 3a, 3c, s3d
Liu Z, Wu C, Pan Y, Liu H, Wang X, Yang Y, et al. NDR2 promotes the antiviral immune response via facilitating TRIM25-mediated RIG-I activation in macrophages. Sci Adv. 2019;5:eaav0163 pubmed publisher
  • western blot; mouse; fig 7a
Liu J, Zhu G, Jia N, Wang W, Wang Y, Yin M, et al. CD9 regulates keratinocyte migration by negatively modulating the sheddase activity of ADAM17. Int J Biol Sci. 2019;15:493-506 pubmed publisher
  • western blot; mouse; loading ...; fig s3a
Li J, Wang Y, Ma M, Jiang S, Zhang X, Zhang Y, et al. Autocrine CTHRC1 activates hepatic stellate cells and promotes liver fibrosis by activating TGF-β signaling. EBioMedicine. 2019;40:43-55 pubmed publisher
  • western blot; human; loading ...; fig s2
Zhang Z, Chen J, Huang W, Ning D, Liu Q, Wang C, et al. FAM134B induces tumorigenesis and epithelial-to-mesenchymal transition via Akt signaling in hepatocellular carcinoma. Mol Oncol. 2019;13:792-810 pubmed publisher
  • western blot; human; fig 5d
Xiao N, Li H, Yu W, Gu C, Fang H, Peng Y, et al. SUMO-specific protease 2 (SENP2) suppresses keratinocyte migration by targeting NDR1 for de-SUMOylation. FASEB J. 2019;33:163-174 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5b
Liang N, Kitts D. Chlorogenic Acid (CGA) Isomers Alleviate Interleukin 8 (IL-8) Production in Caco-2 Cells by Decreasing Phosphorylation of p38 and Increasing Cell Integrity. Int J Mol Sci. 2018;19: pubmed publisher
  • western blot; rat; loading ...; fig 6
Fu J, Yu W, Jiang D. Acidic pH promotes nucleus pulposus cell senescence through activating the p38 MAPK pathway. Biosci Rep. 2018;38: pubmed publisher
  • western blot; mouse; 1:3000; loading ...; fig s4a
Liu Z, Qin Q, Wu C, Li H, Shou J, Yang Y, et al. Downregulated NDR1 protein kinase inhibits innate immune response by initiating an miR146a-STAT1 feedback loop. Nat Commun. 2018;9:2789 pubmed publisher
  • western blot; mouse; loading ...; fig 8a
Xie H, Wang Y, Zhang H, Fan Q, Dai D, Zhuang L, et al. Tubular epithelial C1orf54 mediates protection and recovery from acute kidney injury. J Cell Mol Med. 2018;22:4985-4996 pubmed publisher
  • western blot; human; loading ...; fig 4a
Yang M, Li C, Zhu S, Cao L, Kroemer G, Zeh H, et al. TFAM is a novel mediator of immunogenic cancer cell death. Oncoimmunology. 2018;7:e1431086 pubmed publisher
  • western blot; human; loading ...; fig 1b
Zhu B, Tang L, Chen S, Yin C, Peng S, Li X, et al. Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy. Oncogene. 2018;37:4941-4954 pubmed publisher
  • western blot; mouse; loading ...; fig 3b
Salomè M, Magee A, Yalla K, Chaudhury S, Sarrou E, Carmody R, et al. A Trib2-p38 axis controls myeloid leukaemia cell cycle and stress response signalling. Cell Death Dis. 2018;9:443 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 5
Sheng X, Wang J, Guo J, Xu Y, Jiang H, Zheng C, et al. Effects of Baicalin on Diabetic Cardiac Autonomic Neuropathy Mediated by the P2Y12 Receptor in Rat Stellate Ganglia. Cell Physiol Biochem. 2018;46:986-998 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4a
Chen D, Xie J, Fiskesund R, Dong W, Liang X, Lv J, et al. Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages toward M1 phenotype. Nat Commun. 2018;9:873 pubmed publisher
  • western blot; human; loading ...; fig s5s
Schafer S, Viswanathan S, Widjaja A, Lim W, Moreno Moral A, Delaughter D, et al. IL-11 is a crucial determinant of cardiovascular fibrosis. Nature. 2017;552:110-115 pubmed publisher
  • western blot; mouse; loading ...; fig s6e
Purvis H, Clarke F, Jordan C, Blanco C, Cornish G, Dai X, et al. Protein tyrosine phosphatase PTPN22 regulates IL-1β dependent Th17 responses by modulating dectin-1 signaling in mice. Eur J Immunol. 2018;48:306-315 pubmed publisher
  • western blot; mouse; loading ...; fig s8d
Jiang Y, Lin X, Tang Z, Lee C, Tian G, Du Y, et al. Critical role of caveolin-1 in ocular neovascularization and multitargeted antiangiogenic effects of cavtratin via JNK. Proc Natl Acad Sci U S A. 2017;114:10737-10742 pubmed publisher
  • western blot; mouse; loading ...; fig 7d
Ogura H, Nagatake Kobayashi Y, Adachi J, Tomonaga T, Fujita N, Katayama R. TKI-addicted ROS1-rearranged cells are destined to survival or death by the intensity of ROS1 kinase activity. Sci Rep. 2017;7:5519 pubmed publisher
  • western blot; human; loading ...; fig 4a
Iampietro M, Younan P, Nishida A, Dutta M, Lubaki N, Santos R, et al. Ebola virus glycoprotein directly triggers T lymphocyte death despite of the lack of infection. PLoS Pathog. 2017;13:e1006397 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4l
Ng R, Hussain N, Zhang Q, Chang C, Li H, Fu Y, et al. miRNA-32 Drives Brown Fat Thermogenesis and Trans-activates Subcutaneous White Fat Browning in Mice. Cell Rep. 2017;19:1229-1246 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 6a
Zhong J, Wang H, Chen W, Sun Z, Chen J, Xu Y, et al. Ubiquitylation of MFHAS1 by the ubiquitin ligase praja2 promotes M1 macrophage polarization by activating JNK and p38 pathways. Cell Death Dis. 2017;8:e2763 pubmed publisher
  • western blot; human; fig 3a,3l
Du M, Martin A, HAYS F, Johnson J, FARJO R, Farjo K. Serum retinol-binding protein-induced endothelial inflammation is mediated through the activation of toll-like receptor 4. Mol Vis. 2017;23:185-197 pubmed
  • western blot; rat; 1:1000; loading ...; tbl 2
Han Q, Lin Q, Huang P, Chen M, Hu X, Fu H, et al. Microglia-derived IL-1? contributes to axon development disorders and synaptic deficit through p38-MAPK signal pathway in septic neonatal rats. J Neuroinflammation. 2017;14:52 pubmed publisher
  • western blot; rat; loading ...; fig 3c
Houddane A, Bultot L, Novellasdemunt L, Johanns M, Gueuning M, Vertommen D, et al. Role of Akt/PKB and PFKFB isoenzymes in the control of glycolysis, cell proliferation and protein synthesis in mitogen-stimulated thymocytes. Cell Signal. 2017;34:23-37 pubmed publisher
  • western blot; mouse; loading ...; fig 5b
  • western blot; human; loading ...; fig 5a
Ma C, Lin W, Liu Z, Tang W, Gautam R, Li H, et al. NDR1 protein kinase promotes IL-17- and TNF-α-mediated inflammation by competitively binding TRAF3. EMBO Rep. 2017;18:586-602 pubmed publisher
  • western blot; rat; 1:1000; fig 4A
Wang N, Yao F, Li K, Zhang L, Yin G, Du M, et al. Fisetin regulates astrocyte migration and proliferation in vitro. Int J Mol Med. 2017;39:783-790 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 6a
Dong Q, Fu L, Zhao Y, Tan S, Wang E. Derlin-1 overexpression confers poor prognosis in muscle invasive bladder cancer and contributes to chemoresistance and invasion through PI3K/AKT and ERK/MMP signaling. Oncotarget. 2017;8:17059-17069 pubmed publisher
  • western blot; mouse; loading ...; fig 5d
Zhang H, Qi Y, Yuan Y, Cai L, Xu H, Zhang L, et al. Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation. Sci Rep. 2017;7:41887 pubmed publisher
  • western blot; mouse; loading ...; fig 7a
Xiong X, Liu Y, Mei Y, Peng J, Wang Z, Kong B, et al. Novel Protective Role of Myeloid Differentiation 1 in Pathological Cardiac Remodelling. Sci Rep. 2017;7:41857 pubmed publisher
  • western blot; mouse; 1:1000; fig s7a
Kechele D, Blue R, Zwarycz B, Espenschied S, Mah A, Siegel M, et al. Orphan Gpr182 suppresses ERK-mediated intestinal proliferation during regeneration and adenoma formation. J Clin Invest. 2017;127:593-607 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 10d
Tamamura Y, Katsube K, Mera H, Itokazu M, Wakitani S. Irx3 and Bmp2 regulate mouse mesenchymal cell chondrogenic differentiation in both a Sox9-dependent and -independent manner. J Cell Physiol. 2017;232:3317-3336 pubmed publisher
  • western blot; rat; 1:1000; fig 1b
Grossi M, Bhattachariya A, Nordström I, Turczynska K, Svensson D, Albinsson S, et al. Pyk2 inhibition promotes contractile differentiation in arterial smooth muscle. J Cell Physiol. 2017;232:3088-3102 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3d
Su C, Gao X, Yang W, Zhao Y, Fu X, Cui X, et al. Phosphorylation of Tudor-SN, a novel substrate of JNK, is involved in the efficient recruitment of Tudor-SN into stress granules. Biochim Biophys Acta Mol Cell Res. 2017;1864:562-571 pubmed publisher
  • western blot; human; loading ...; fig 5
Ohtsuka T, Sakaguchi M, Yamamoto H, Tomida S, Takata K, Shien K, et al. Interaction of cytokeratin 19 head domain and HER2 in the cytoplasm leads to activation of HER2-Erk pathway. Sci Rep. 2016;6:39557 pubmed publisher
  • western blot; mouse; 1:1000; fig 2
Möllmann J, Kahles F, Lebherz C, Kappel B, Baeck C, Tacke F, et al. The PDE4 inhibitor roflumilast reduces weight gain by increasing energy expenditure and leads to improved glucose metabolism. Diabetes Obes Metab. 2017;19:496-508 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 6b
Farsam V, Basu A, Gatzka M, Treiber N, Schneider L, Mulaw M, et al. Senescent fibroblast-derived Chemerin promotes squamous cell carcinoma migration. Oncotarget. 2016;7:83554-83569 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 9a
Choi S, Piao Z, Jin L, Kim J, Kim G, Ryu Y, et al. Piceatannol Attenuates Renal Fibrosis Induced by Unilateral Ureteral Obstruction via Downregulation of Histone Deacetylase 4/5 or p38-MAPK Signaling. PLoS ONE. 2016;11:e0167340 pubmed publisher
  • western blot; mouse; loading ...; fig 1e
Fernández Verdejo R, Vanwynsberghe A, Essaghir A, Demoulin J, Hai T, Deldicque L, et al. Activating transcription factor 3 attenuates chemokine and cytokine expression in mouse skeletal muscle after exercise and facilitates molecular adaptation to endurance training. FASEB J. 2017;31:840-851 pubmed publisher
  • western blot; mouse; loading ...; fig s3h, s4a
Newton K, Wickliffe K, Maltzman A, Dugger D, Strasser A, Pham V, et al. RIPK1 inhibits ZBP1-driven necroptosis during development. Nature. 2016;540:129-133 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig s5d
Ulland T, Jain N, Hornick E, Elliott E, Clay G, Sadler J, et al. Nlrp12 mutation causes C57BL/6J strain-specific defect in neutrophil recruitment. Nat Commun. 2016;7:13180 pubmed publisher
  • western blot; human; loading ...; fig 3
Jiang Y, Zeng Y, Huang X, Qin Y, Luo W, Xiang S, et al. Nur77 attenuates endothelin-1 expression via downregulation of NF-κB and p38 MAPK in A549 cells and in an ARDS rat model. Am J Physiol Lung Cell Mol Physiol. 2016;311:L1023-L1035 pubmed publisher
  • western blot; mouse; loading ...; fig 3d
Huai W, Song H, Yu Z, Wang W, Han L, Sakamoto T, et al. Mint3 potentiates TLR3/4- and RIG-I-induced IFN-? expression and antiviral immune responses. Proc Natl Acad Sci U S A. 2016;113:11925-11930 pubmed
  • western blot; human; loading ...; fig 4a
Lu W, Shi J, Zhang J, Lv Z, Guo F, Huang H, et al. CXCL12/CXCR4 Axis Regulates Aggrecanase Activation and Cartilage Degradation in a Post-Traumatic Osteoarthritis Rat Model. Int J Mol Sci. 2016;17: pubmed
  • western blot; human; fig 4
Ang Z, Er J, Tan N, Lu J, Liou Y, Grosse J, et al. Human and mouse monocytes display distinct signalling and cytokine profiles upon stimulation with FFAR2/FFAR3 short-chain fatty acid receptor agonists. Sci Rep. 2016;6:34145 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 6d
Cao R, Meng Z, Liu T, Wang G, Qian G, Cao T, et al. Decreased TRPM7 inhibits activities and induces apoptosis of bladder cancer cells via ERK1/2 pathway. Oncotarget. 2016;7:72941-72960 pubmed publisher
  • western blot; human; loading ...; fig 6a
Shi Y, Yu Y, Wang Z, Wang H, Bieerkehazhi S, Zhao Y, et al. Second-generation proteasome inhibitor carfilzomib enhances doxorubicin-induced cytotoxicity and apoptosis in breast cancer cells. Oncotarget. 2016;7:73697-73710 pubmed publisher
  • western blot; mouse; loading ...; fig 6b, 6d
Janowski A, Colegio O, Hornick E, McNiff J, Martin M, Badovinac V, et al. NLRC4 suppresses melanoma tumor progression independently of inflammasome activation. J Clin Invest. 2016;126:3917-3928 pubmed publisher
  • western blot; mouse; loading ...; fig 5a
Ando Y, Oku T, Tsuji T. Platelet Supernatant Suppresses LPS-Induced Nitric Oxide Production from Macrophages Accompanied by Inhibition of NF-?B Signaling and Increased Arginase-1 Expression. PLoS ONE. 2016;11:e0162208 pubmed publisher
  • western blot; rat; fig 2
Zhang Y, Hu S, Chen Y, Guo M, Wang S. Hepatocyte growth factor inhibits hypoxia/reoxygenation-induced activation of xanthine oxidase in endothelial cells through the JAK2 signaling pathway. Int J Mol Med. 2016;38:1055-62 pubmed publisher
  • western blot; human; fig 4a
Cheng G, Gao F, Sun X, Bi H, Zhu Y. Paris saponin VII suppresses osteosarcoma cell migration and invasion by inhibiting MMP?2/9 production via the p38 MAPK signaling pathway. Mol Med Rep. 2016;14:3199-205 pubmed publisher
  • western blot; human; fig 1
Zhou Q, Yu X, Demirkaya E, Deuitch N, Stone D, Tsai W, et al. Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease. Proc Natl Acad Sci U S A. 2016;113:10127-32 pubmed publisher
  • western blot; mouse; fig 4c
Wittmann A, Lamprinaki D, Bowles K, Katzenellenbogen E, Knirel Y, Whitfield C, et al. Dectin-2 Recognizes Mannosylated O-antigens of Human Opportunistic Pathogens and Augments Lipopolysaccharide Activation of Myeloid Cells. J Biol Chem. 2016;291:17629-38 pubmed publisher
  • western blot; mouse; fig 1
Tortola L, Nitsch R, Bertrand M, Kogler M, Redouane Y, Kozieradzki I, et al. The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate. Cell Rep. 2016;15:1481-1492 pubmed publisher
  • western blot; pigs ; fig 6
Ren W, Yin J, Chen S, Duan J, Liu G, Li T, et al. Proteome analysis for the global proteins in the jejunum tissues of enterotoxigenic Escherichia coli -infected piglets. Sci Rep. 2016;6:25640 pubmed publisher
  • western blot; human; loading ...; fig 4g
Wang Y, Cao J, Fan Y, Xie Y, Xu Z, Yin Z, et al. Artemisinin inhibits monocyte adhesion to HUVECs through the NF-?B and MAPK pathways in vitro. Int J Mol Med. 2016;37:1567-75 pubmed publisher
  • western blot; human; loading ...; fig 6a
Wang X, Wang N, Li H, Liu M, Cao F, Yu X, et al. Up-Regulation of PAI-1 and Down-Regulation of uPA Are Involved in Suppression of Invasiveness and Motility of Hepatocellular Carcinoma Cells by a Natural Compound Berberine. Int J Mol Sci. 2016;17:577 pubmed publisher
  • western blot; mouse; loading ...; fig 4a
Yu Z, Chen T, Li X, Yang M, Tang S, Zhu X, et al. Lys29-linkage of ASK1 by Skp1-Cullin 1-Fbxo21 ubiquitin ligase complex is required for antiviral innate response. elife. 2016;5: pubmed publisher
  • western blot; human; fig 3
Huang W, Zhao H, Dong H, Wu Y, Yao L, Zou F, et al. High-mobility group box 1 impairs airway epithelial barrier function through the activation of the RAGE/ERK pathway. Int J Mol Med. 2016;37:1189-98 pubmed publisher
  • western blot; human; fig 7
Braley A, Kwak T, Jules J, Harja E, Landgraf R, Hudson B. Regulation of Receptor for Advanced Glycation End Products (RAGE) Ectodomain Shedding and Its Role in Cell Function. J Biol Chem. 2016;291:12057-73 pubmed publisher
  • western blot; rat; 1:1000; fig 6
Huo L, Shi W, Chong L, Wang J, Zhang K, Li Y. Asiatic acid inhibits left ventricular remodeling and improves cardiac function in a rat model of myocardial infarction. Exp Ther Med. 2016;11:57-64 pubmed
  • western blot; human; fig 4
Wu X, Yang L, Zheng Z, Li Z, Shi J, Li Y, et al. Src promotes cutaneous wound healing by regulating MMP-2 through the ERK pathway. Int J Mol Med. 2016;37:639-48 pubmed publisher
  • western blot; human; 1:1000; fig 5
Xu Y, Wu D, Zheng W, Yu F, Yang F, Yao Y, et al. Proteome profiling of cadmium-induced apoptosis by antibody array analyses in human bronchial epithelial cells. Oncotarget. 2016;7:6146-58 pubmed publisher
  • western blot; rat; 1:1000; fig 6
Chen P, Li J, Huo Y, Lu J, Wan L, Li B, et al. Orphan nuclear receptor NR4A2 inhibits hepatic stellate cell proliferation through MAPK pathway in liver fibrosis. Peerj. 2015;3:e1518 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; fig s4
Yamano S, Gi M, Tago Y, Doi K, Okada S, Hirayama Y, et al. Role of deltaNp63(pos)CD44v(pos) cells in the development of N-nitroso-tris-chloroethylurea-induced peripheral-type mouse lung squamous cell carcinomas. Cancer Sci. 2016;107:123-32 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5c
Huang X, Huang S, Guo F, Xu F, Cheng P, Ye Y, et al. Dose-dependent inhibitory effects of zoledronic acid on osteoblast viability and function in vitro. Mol Med Rep. 2016;13:613-22 pubmed publisher
  • western blot; human; loading ...; fig 2b, 2c
Zhou Q, Wang H, Schwartz D, Stoffels M, Park Y, Zhang Y, et al. Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease. Nat Genet. 2016;48:67-73 pubmed publisher
  • western blot; human; fig 5b
Giri K, Pabelick C, Mukherjee P, Prakash Y. Hepatoma derived growth factor (HDGF) dynamics in ovarian cancer cells. Apoptosis. 2016;21:329-39 pubmed publisher
  • western blot; mouse
McIlroy G, Tammireddy S, Maskrey B, Grant L, Doherty M, Watson D, et al. Fenretinide mediated retinoic acid receptor signalling and inhibition of ceramide biosynthesis regulates adipogenesis, lipid accumulation, mitochondrial function and nutrient stress signalling in adipocytes and adipose tissue. Biochem Pharmacol. 2016;100:86-97 pubmed publisher
  • western blot; human; fig s1
Elder M, Webster S, Williams D, Gaston J, Goodall J. TSLP production by dendritic cells is modulated by IL-1β and components of the endoplasmic reticulum stress response. Eur J Immunol. 2016;46:455-63 pubmed publisher
  • western blot; human; fig 3
Waye S, Naeem A, Choudhry M, Parasido E, Tricoli L, Sivakumar A, et al. The p53 tumor suppressor protein protects against chemotherapeutic stress and apoptosis in human medulloblastoma cells. Aging (Albany NY). 2015;7:854-68 pubmed
  • western blot; rat; 1:1000; fig 5a
Li W, Wei S, Liu C, Song M, Wu H, Yang Y. Regulation of the osteogenic and adipogenic differentiation of bone marrow-derived stromal cells by extracellular uridine triphosphate: The role of P2Y2 receptor and ERK1/2 signaling. Int J Mol Med. 2016;37:63-73 pubmed publisher
  • western blot; human; 1:1000; fig 6
Qiu H, Liu B, Liu W, Liu S. Interleukin-27 enhances TNF-α-mediated activation of human coronary artery endothelial cells. Mol Cell Biochem. 2016;411:1-10 pubmed publisher
  • western blot; human; fig 6
Unni A, Lockwood W, Zejnullahu K, Lee Lin S, Varmus H. Evidence that synthetic lethality underlies the mutual exclusivity of oncogenic KRAS and EGFR mutations in lung adenocarcinoma. elife. 2015;4:e06907 pubmed publisher
  • western blot; human
Nishioka C, Ikezoe T, Yang J, Yokoyama A. Tetraspanin Family Member, CD82, Regulates Expression of EZH2 via Inactivation of p38 MAPK Signaling in Leukemia Cells. PLoS ONE. 2015;10:e0125017 pubmed publisher
  • western blot; mouse; 1:1000; fig 2
Ko R, Park J, Ha H, Choi Y, Lee S. Glycogen synthase kinase 3β ubiquitination by TRAF6 regulates TLR3-mediated pro-inflammatory cytokine production. Nat Commun. 2015;6:6765 pubmed publisher
  • western blot; mouse; fig 10B
Pone E, Lam T, Lou Z, Wang R, Chen Y, Liu D, et al. B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses. J Immunol. 2015;194:3065-78 pubmed publisher
  • western blot; mouse; 1:1000; fig 5a
Wei Z, Yu D, Bi Y, Cao Y. A disintegrin and metalloprotease 17 promotes microglial cell survival via epidermal growth factor receptor signalling following spinal cord injury. Mol Med Rep. 2015;12:63-70 pubmed publisher
  • western blot; human
Lee J, Chung L, Chen Y, Feng T, Chen W, Juang H. Upregulation of B-cell translocation gene 2 by epigallocatechin-3-gallate via p38 and ERK signaling blocks cell proliferation in human oral squamous cell carcinoma cells. Cancer Lett. 2015;360:310-8 pubmed publisher
  • western blot; human; fig 1
Blanchard Z, Paul B, Craft B, ElShamy W. BRCA1-IRIS inactivation overcomes paclitaxel resistance in triple negative breast cancers. Breast Cancer Res. 2015;17:5 pubmed publisher
  • western blot; human
Rochman M, Kartashov A, Caldwell J, Collins M, Stucke E, Kc K, et al. Neurotrophic tyrosine kinase receptor 1 is a direct transcriptional and epigenetic target of IL-13 involved in allergic inflammation. Mucosal Immunol. 2015;8:785-98 pubmed publisher
  • western blot; mouse
Morioka T, Sakabe M, Ioka T, Iguchi T, Mizuta K, Hattammaru M, et al. An important role of endothelial hairy-related transcription factors in mouse vascular development. Genesis. 2014;52:897-906 pubmed publisher
  • western blot; human
Ishaq M, Evans M, Ostrikov K. Atmospheric pressure gas plasma-induced colorectal cancer cell death is mediated by Nox2-ASK1 apoptosis pathways and oxidative stress is mitigated by Srx-Nrf2 anti-oxidant system. Biochim Biophys Acta. 2014;1843:2827-37 pubmed publisher
  • western blot; mouse; fig s8
Dannappel M, Vlantis K, Kumari S, Polykratis A, Kim C, Wachsmuth L, et al. RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis. Nature. 2014;513:90-4 pubmed publisher
  • western blot; pigs ; 1:500
Zhang S, Ren M, Zeng X, He P, Ma X, Qiao S. Leucine stimulates ASCT2 amino acid transporter expression in porcine jejunal epithelial cell line (IPEC-J2) through PI3K/Akt/mTOR and ERK signaling pathways. Amino Acids. 2014;46:2633-42 pubmed publisher
  • western blot; mouse
Ren W, Duan J, Yin J, Liu G, Cao Z, Xiong X, et al. Dietary L-glutamine supplementation modulates microbial community and activates innate immunity in the mouse intestine. Amino Acids. 2014;46:2403-13 pubmed publisher
  • western blot; human
Martin V, Corso S, Comoglio P, Giordano S. Increase of MET gene copy number confers resistance to a monovalent MET antibody and establishes drug dependence. Mol Oncol. 2014;8:1561-74 pubmed publisher
  • western blot; rat; 1:1000
Huang L, Zhu G, Deng Y, Jiang W, Fang M, Chen C, et al. Hypertonic saline alleviates cerebral edema by inhibiting microglia-derived TNF-? and IL-1?-induced Na-K-Cl Cotransporter up-regulation. J Neuroinflammation. 2014;11:102 pubmed publisher
  • western blot; human
Liu B, Cao Y, Huizinga T, Hafler D, Toes R. TLR-mediated STAT3 and ERK activation controls IL-10 secretion by human B cells. Eur J Immunol. 2014;44:2121-9 pubmed publisher
  • western blot; rat
Codeluppi S, Fernández Zafra T, Sandor K, Kjell J, Liu Q, Abrams M, et al. Interleukin-6 secretion by astrocytes is dynamically regulated by PI3K-mTOR-calcium signaling. PLoS ONE. 2014;9:e92649 pubmed publisher
  • western blot; human
Singel S, Batten K, Cornelius C, Jia G, Fasciani G, Barron S, et al. Receptor-interacting protein kinase 2 promotes triple-negative breast cancer cell migration and invasion via activation of nuclear factor-kappaB and c-Jun N-terminal kinase pathways. Breast Cancer Res. 2014;16:R28 pubmed publisher
  • western blot; rat
Qian H, Shi J, Fan T, Lv J, Chen S, Song C, et al. Sophocarpine attenuates liver fibrosis by inhibiting the TLR4 signaling pathway in rats. World J Gastroenterol. 2014;20:1822-32 pubmed publisher
  • western blot; human; 1:1000
Zhong X, Wang H, Huang S. Endothelin-1 induces interleukin-18 expression in human osteoblasts. Arch Oral Biol. 2014;59:289-96 pubmed publisher
  • western blot; mouse; 1:2000; fig 8
Das R, Xu S, Quan X, Nguyen T, Kong I, Chung C, et al. Upregulation of mitochondrial Nox4 mediates TGF-?-induced apoptosis in cultured mouse podocytes. Am J Physiol Renal Physiol. 2014;306:F155-67 pubmed publisher
  • western blot; rat
Li L, Ginet V, Liu X, Vergun O, Tuittila M, Mathieu M, et al. The nNOS-p38MAPK pathway is mediated by NOS1AP during neuronal death. J Neurosci. 2013;33:8185-201 pubmed publisher
Nüchel J, Tauber M, Nolte J, Morgelin M, Türk C, Eckes B, et al. An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress. Mol Cell. 2021;: pubmed publisher
Wang Z, Li Y, Wang K, Wang L, You B, Zhao D, et al. miR-5089-5p suppresses castration-resistant prostate cancer resistance to enzalutamide and metastasis via miR-5089-5p/SPINK1/ MAPK/MMP9 signaling. Aging (Albany NY). 2020;12:14418-14433 pubmed publisher
Johnston E, Gillis T. Short-term cyclical stretch phosphorylates p38 and ERK1/2 MAPKs in cultured fibroblasts from the hearts of rainbow trout, Oncorhynchus mykiss. Biol Open. 2020;9: pubmed publisher
Qin S, Jiang C, Gao J. Transcriptional factor Nrf2 is essential for aggresome formation during proteasome inhibition. Biomed Rep. 2019;11:241-252 pubmed publisher
Kashyap A, Fernandez Rodriguez L, Zhao Y, Monaco G, Trefny M, Yoshida N, et al. GEF-H1 Signaling upon Microtubule Destabilization Is Required for Dendritic Cell Activation and Specific Anti-tumor Responses. Cell Rep. 2019;28:3367-3380.e8 pubmed publisher
Zeitz M, Calhoun P, James C, Taetzsch T, George K, Robel S, et al. Dynamic UTR Usage Regulates Alternative Translation to Modulate Gap Junction Formation during Stress and Aging. Cell Rep. 2019;27:2737-2747.e5 pubmed publisher
Zhang L, Chen J, Ning D, Liu Q, Wang C, Zhang Z, et al. FBXO22 promotes the development of hepatocellular carcinoma by regulating the ubiquitination and degradation of p21. J Exp Clin Cancer Res. 2019;38:101 pubmed publisher
Ng S, Jorge S, Malik M, Britten J, Su S, Armstrong C, et al. A-Kinase Anchoring Protein 13 (AKAP13) Augments Progesterone Signaling in Uterine Fibroid Cells. J Clin Endocrinol Metab. 2019;104:970-980 pubmed publisher
Ma F, Chang X, Wang G, Zhou H, Ma Z, Lin H, et al. Streptococcus Suis Serotype 2 Stimulates Neutrophil Extracellular Traps Formation via Activation of p38 MAPK and ERK1/2. Front Immunol. 2018;9:2854 pubmed publisher
Reis L, Ramos Sanchez E, Petitto Assis F, Nerland A, Hernandez Valladares M, Selheim F, et al. Insulin-Like Growth Factor-I as an Effector Element of the Cytokine IL-4 in the Development of a Leishmania major Infection. Mediators Inflamm. 2018;2018:9787128 pubmed publisher
He Y, Yuan X, Li Y, Zhong C, Liu Y, Qian H, et al. Loss of Gαq impairs regulatory B-cell function. Arthritis Res Ther. 2018;20:186 pubmed publisher
Wakamatsu T, Yamamoto S, Ito T, Sato Y, Matsuo K, Takahashi Y, et al. Indoxyl Sulfate Promotes Macrophage IL-1β Production by Activating Aryl Hydrocarbon Receptor/NF-κ/MAPK Cascades, but the NLRP3 inflammasome Was Not Activated. Toxins (Basel). 2018;10: pubmed publisher
Robitaille A, Caron E, Zucchini N, Mukawera E, Adam D, Mariani M, et al. DUSP1 regulates apoptosis and cell migration, but not the JIP1-protected cytokine response, during Respiratory Syncytial Virus and Sendai Virus infection. Sci Rep. 2017;7:17388 pubmed publisher
Xiao P, Huang X, Huang L, Yang J, Li A, Shen K, et al. G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling. Exp Cell Res. 2017;360:273-280 pubmed publisher
Liu Q, Zhang S, Chen G, Zhou H. E3 ubiquitin ligase Nedd4 inhibits AP-1 activity and TNF-α production through targeting p38α for polyubiquitination and subsequent degradation. Sci Rep. 2017;7:4521 pubmed publisher
Mei X, Wang H, Li J, Liu X, Lu X, Li Y, et al. Dusuqing granules (DSQ) suppress inflammation in Klebsiella pneumonia rat via NF-?B/MAPK signaling. BMC Complement Altern Med. 2017;17:216 pubmed publisher
Hudson G, Flannigan K, Erickson S, Vicentini F, Zamponi A, Hirota C, et al. Constitutive androstane receptor regulates the intestinal mucosal response to injury. Br J Pharmacol. 2017;174:1857-1871 pubmed publisher
Zhou Y, Yang Q, Xu H, Zhang J, Deng H, Gao H, et al. miRNA-221-3p Enhances the Secretion of Interleukin-4 in Mast Cells through the Phosphatase and Tensin Homolog/p38/Nuclear Factor-kappaB Pathway. PLoS ONE. 2016;11:e0148821 pubmed publisher
Hou L, Li Y, Song H, Zhang Z, Sun Y, Zhang X, et al. Protective Macroautophagy Is Involved in Vitamin E Succinate Effects on Human Gastric Carcinoma Cell Line SGC-7901 by Inhibiting mTOR Axis Phosphorylation. PLoS ONE. 2015;10:e0132829 pubmed publisher
Williams C, Bernard J, Demory Beckler M, Almohazey D, Washington M, Smith J, et al. ERBB4 is over-expressed in human colon cancer and enhances cellular transformation. Carcinogenesis. 2015;36:710-8 pubmed publisher
Martin I, Cabán Hernández K, Figueroa Santiago O, Espino A. Fasciola hepatica fatty acid binding protein inhibits TLR4 activation and suppresses the inflammatory cytokines induced by lipopolysaccharide in vitro and in vivo. J Immunol. 2015;194:3924-36 pubmed publisher
Liu J, Lin X, Yang X, Zhou L, He S, Zhuang S, et al. A novel AP-1/miR-101 regulatory feedback loop and its implication in the migration and invasion of hepatoma cells. Nucleic Acids Res. 2014;42:12041-51 pubmed publisher
Yu G, Lee Y, Cheng C, Wu C, Song J, Gallick G, et al. RSK promotes prostate cancer progression in bone through ING3, CKAP2, and PTK6-mediated cell survival. Mol Cancer Res. 2015;13:348-57 pubmed publisher
Zhou H, Guo W, Zhao Y, Wang Y, Zha R, Ding J, et al. MicroRNA-135a acts as a putative tumor suppressor by directly targeting very low density lipoprotein receptor in human gallbladder cancer. Cancer Sci. 2014;105:956-65 pubmed publisher
Dai J, Chen X, Zhu D, Wan Q, Chen C, Wang G, et al. Panax notoginseng saponins inhibit areca nut extract-induced oral submucous fibrosis in vitro. J Oral Pathol Med. 2014;43:464-70 pubmed publisher
Zeng L, Yao Y, Wang D, Chen X. Effect of microcavitary alginate hydrogel with different pore sizes on chondrocyte culture for cartilage tissue engineering. Mater Sci Eng C Mater Biol Appl. 2014;34:168-75 pubmed publisher
Sun P, Zhou K, Wang S, Li P, Chen S, Lin G, et al. Involvement of MAPK/NF-κB signaling in the activation of the cholinergic anti-inflammatory pathway in experimental colitis by chronic vagus nerve stimulation. PLoS ONE. 2013;8:e69424 pubmed publisher
Tian B, Qin A, Shao Z, Jiang T, Zhai Z, Li H, et al. OA-4 inhibits osteoclast formation and bone resorption via suppressing RANKL induced P38 signaling pathway. Curr Med Chem. 2014;21:641-9 pubmed
Cao Y, Xia D, Qi S, Du J, Ma P, Wang S, et al. Epiregulin can promote proliferation of stem cells from the dental apical papilla via MEK/Erk and JNK signalling pathways. Cell Prolif. 2013;46:447-56 pubmed publisher
product information
SKU :
8690P
Product-Name :
p38 MAPK (D13E1) XP® Rabbit mAb
Size :
40 ul
Price-(USD) :
135 USD
Species-x-Reactivity :
H, M, R, Hm, Mk, Pg, (C)
Applications :
Flow cytometry
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
40
Host :
Rabbit
Target :
p38-alpha MAPK/p38-beta MAPK/p38-gamma MAPK
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.