product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Axl (C89E7) Rabbit mAb
catalog :
8661
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
C89E7
reactivity :
black ferret, human, mouse
application :
western blot, immunohistochemistry, flow cytometry, other
more info or order :
Cell Signaling Technology product webpage
citations: 17
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig s1c
Greer Y, Gilbert S, Gril B, Narwal R, Peacock Brooks D, Tice D, et al. MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgrowth of metastatic triple-negative breast cancer. Breast Cancer Res. 2019;21:27 pubmed publisher
  • immunohistochemistry; black ferret; 1:100; loading ...; fig 11
Hutchinson E, Chatterjee M, Reyes L, Djankpa F, Valiant W, Dardzinski B, et al. The effect of Zika virus infection in the ferret. J Comp Neurol. 2019;527:1706-1719 pubmed publisher
  • other; human; loading ...; fig 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 1f
Chen J, Yang Y, Yang Y, Zou P, Chen J, He Y, et al. AXL promotes Zika virus infection in astrocytes by antagonizing type I interferon signalling. Nat Microbiol. 2018;3:302-309 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 7d
Caino M, Seo J, Wang Y, Rivadeneira D, Gabrilovich D, Kim E, et al. Syntaphilin controls a mitochondrial rheostat for proliferation-motility decisions in cancer. J Clin Invest. 2017;127:3755-3769 pubmed publisher
  • western blot; human; loading ...; fig 1a
Baumann C, Ullrich A, Torka R. GAS6-expressing and self-sustaining cancer cells in 3D spheroids activate the PDK-RSK-mTOR pathway for survival and drug resistance. Mol Oncol. 2017;11:1430-1447 pubmed publisher
  • western blot; human; loading ...; fig s5b
Retallack H, Di Lullo E, Arias C, Knopp K, Laurie M, Sandoval Espinosa C, et al. Zika virus cell tropism in the developing human brain and inhibition by azithromycin. Proc Natl Acad Sci U S A. 2016;113:14408-14413 pubmed
  • western blot; human; 1:1000; fig 2
Lehmann W, Mossmann D, Kleemann J, Mock K, Meisinger C, Brummer T, et al. ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types. Nat Commun. 2016;7:10498 pubmed publisher
Hoj J, Mayro B, Pendergast A. A TAZ-AXL-ABL2 Feed-Forward Signaling Axis Promotes Lung Adenocarcinoma Brain Metastasis. Cell Rep. 2019;29:3421-3434.e8 pubmed publisher
Pujhari S, Brustolin M, Macias V, Nissly R, Nomura M, Kuchipudi S, et al. Heat shock protein 70 (Hsp70) mediates Zika virus entry, replication, and egress from host cells. Emerg Microbes Infect. 2019;8:8-16 pubmed publisher
Li W, Xiong X, Abdalla A, Alejo S, Zhu L, Lu F, et al. HGF-induced formation of the MET-AXL-ELMO2-DOCK180 complex promotes RAC1 activation, receptor clustering, and cancer cell migration and invasion. J Biol Chem. 2018;293:15397-15418 pubmed publisher
Alimonti J, Ribecco Lutkiewicz M, Sodja C, Jezierski A, Stanimirovic D, Liu Q, et al. Zika virus crosses an in vitro human blood brain barrier model. Fluids Barriers CNS. 2018;15:15 pubmed publisher
Zhang G, Wu L, Mender I, Barzily Rokni M, Hammond M, Ope O, et al. Induction of Telomere Dysfunction Prolongs Disease Control of Therapy-Resistant Melanoma. Clin Cancer Res. 2018;24:4771-4784 pubmed publisher
Merilahti J, Ojala V, Knittle A, Pulliainen A, Elenius K. Genome-wide screen of gamma-secretase-mediated intramembrane cleavage of receptor tyrosine kinases. Mol Biol Cell. 2017;28:3123-3131 pubmed publisher
von Mässenhausen A, Brägelmann J, Billig H, Thewes B, Queisser A, Vogel W, et al. Implication of the Receptor Tyrosine Kinase AXL in Head and Neck Cancer Progression. Int J Mol Sci. 2016;18: pubmed publisher
Ohno S, Itano K, Harada Y, Asada K, Oikawa K, Kashiwazako M, et al. Development of Novel Small Hairpin RNAs That do not Require Processing by Dicer or AGO2. Mol Ther. 2016;24:1278-89 pubmed publisher
Cheng P, Phillips E, Kim S, Taylor D, Hielscher T, Puccio L, et al. Kinome-wide shRNA screen identifies the receptor tyrosine kinase AXL as a key regulator for mesenchymal glioblastoma stem-like cells. Stem Cell Reports. 2015;4:899-913 pubmed publisher
product information
SKU :
8661S
Product-Name :
Axl (C89E7) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, Mk
Applications :
Flow cytometry
Product-Category :
RTK
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
138
Host :
Rabbit
Target :
Axl
Primary-Protein :
Axl
Alt-Names :
AXL,AXL oncogene,AXL receptor tyrosine kinase,AXL transforming sequence/gene,JTK11,Tyrosine-protein kinase receptor UFO,UFO,oncogene AXL
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.