Estrogen Receptor α (D8H8) Rabbit mAb | Cell Signaling Technology 8644 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Estrogen Receptor α (D8H8) Rabbit mAb

catalog :

8644

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

D8H8

reactivity :

human, rat

application :

western blot, immunoprecipitation, chromatin immunoprecipitation

more info or order :

Cell Signaling Technology product webpage

citations: 16

Published Application/Species/Sample/Dilution	Reference
chromatin immunoprecipitation; human; 1:200; loading ...; fig 3b western blot; human; loading ...	Tsoi H, Man E, Chau K, Khoo U. Targeting the IL-6/STAT3 Signalling Cascade to Reverse Tamoxifen Resistance in Estrogen Receptor Positive Breast Cancer. Cancers (Basel). 2021;13: pubmed publisher
western blot; human; loading ...; fig 3a	Xia X, Huang C, Liao Y, Liu Y, He J, Shao Z, et al. The deubiquitinating enzyme USP15 stabilizes ERα and promotes breast cancer progression. Cell Death Dis. 2021;12:329 pubmed publisher
western blot; human; 1:1000; loading ...; fig 1a, 2c, 3e, 7g	Chen X, Wang K, Guo W, Li L, Yu P, Sun X, et al. UCH-L1-mediated Down-regulation of Estrogen Receptor α Contributes to Insensitivity to Endocrine Therapy for Breast Cancer. Theranostics. 2020;10:1833-1848 pubmed publisher
western blot; human; loading ...; fig 1a	Jiang S, Zhang M, Zhang Y, Zhou W, Zhu T, Ruan Q, et al. WNT5B governs the phenotype of basal-like breast cancer by activating WNT signaling. Cell Commun Signal. 2019;17:109 pubmed publisher
western blot; human; loading ...; fig s2	Greer Y, Gilbert S, Gril B, Narwal R, Peacock Brooks D, Tice D, et al. MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgrowth of metastatic triple-negative breast cancer. Breast Cancer Res. 2019;21:27 pubmed publisher
western blot; human; loading ...; fig 4a	SÃ¡nchez Morgan N, Kirsch K, Trackman P, Sonenshein G. UXT Is a LOX-PP Interacting Protein That Modulates Estrogen Receptor Alpha Activity in Breast Cancer Cells. J Cell Biochem. 2017;118:2347-2356 pubmed publisher
immunoprecipitation; human; loading ...; fig ED8g western blot; human; 1:500; loading ...; fig 2c, 4b, 4e,ED4b	Britschgi A, Duss S, Kim S, Couto J, Brinkhaus H, Koren S, et al. The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα. Nature. 2017;541:541-545 pubmed publisher
western blot; human; 1:1000; loading ...; fig 4C	Yu H, Jiang Y, Liu L, Shan W, Chu X, Yang Z, et al. Integrative genomic and transcriptomic analysis for pinpointing recurrent alterations of plant homeodomain genes and their clinical significance in breast cancer. Oncotarget. 2017;8:13099-13115 pubmed publisher
western blot; human; loading ...; fig 2g	Kang M, Jeong K, Kim W, Lee H, Gong G, Suh N, et al. Musashi RNA-binding protein 2 regulates estrogen receptor 1 function in breast cancer. Oncogene. 2017;36:1745-1752 pubmed publisher
western blot; human; 1:1000; tbl s6	Mair B, Konopka T, Kerzendorfer C, Sleiman K, Salic S, Serra V, et al. Gain- and Loss-of-Function Mutations in the Breast Cancer Gene GATA3 Result in Differential Drug Sensitivity. PLoS Genet. 2016;12:e1006279 pubmed publisher
western blot; rat; 1:500; fig s2	Radhika N, Govindaraj V, Sarangi S, Rao A. Neonatal exposure to 17Î²-estradiol down-regulates the expression of synaptogenesis related genes in selected brain regions of adult female rats. Life Sci. 2015;141:1-7 pubmed publisher
western blot; human; fig 1	Zhang Y, Wei X, Liang Y, Chen W, Zhang F, Bai J, et al. Over-Expressed Twist Associates with Markers of Epithelial Mesenchymal Transition and Predicts Poor Prognosis in Breast Cancers via ERK and Akt Activation. PLoS ONE. 2015;10:e0135851 pubmed publisher
western blot; human	Ohoka N, Nagai K, Hattori T, Okuhira K, Shibata N, Cho N, et al. Cancer cell death induced by novel small molecules degrading the TACC3 protein via the ubiquitin-proteasome pathway. Cell Death Dis. 2014;5:e1513 pubmed publisher
western blot; human	Li L, Wang Q, Lv X, Sha L, Qin H, Wang L, et al. Expression and localization of estrogen receptor in human breast cancer and its clinical significance. Cell Biochem Biophys. 2015;71:63-8 pubmed publisher
	Antognelli C, Palumbo I, Aristei C, Talesa V. Glyoxalase I inhibition induces apoptosis in irradiated MCF-7 cells via a novel mechanism involving Hsp27, p53 and NF-?B. Br J Cancer. 2014;111:395-406 pubmed publisher
	Pedroni S, Turban S, Kipari T, Dunbar D, McInnes K, Saunders P, et al. Pregnancy in obese mice protects selectively against visceral adiposity and is associated with increased adipocyte estrogen signalling. PLoS ONE. 2014;9:e94680 pubmed publisher

product information

SKU :

8644S

Product-Name :

Estrogen Receptor α (D8H8) Rabbit mAb

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

Applications :

Chromatin Immunoprecipitation

Product-Category :

Nuclear Receptor Signaling

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

Host :

Rabbit

Target :

ER-alpha

Primary-Protein :

ER-alpha

Alt-Names :

DKFZp686N23123,ER,ER-alpha,ESR,ESR1,ESRA,Era,Estradiol receptor,Estrogen receptor,NR3A1,Nuclear receptor subfamily 3 group A member 1,estrogen receptor 1,estrogen receptor alpha delta 3*,4,5,6,7*/819-2 isoform,estrogen receptor alpha delta 4 +49 isoform,estrogen receptor alpha delta 4*,5,6,7*/654 isoform

more info or order :

Cell Signaling Technology product webpage